ACR Meeting Abstracts

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Abstracts tagged "Imaging"

  • Abstract Number: 2119 • ACR Convergence 2024

    IL-17 Blockade Therapy Improves Symptoms in Patients with Active Axial Spondyloarthritis Without Occurrence of New Vertebral Fractures

    Chloe Heiting1, Donald McMahon1, Douglas Mintz1, Weijia Yuan1, Insa Mannstadt1, Linda A Russell1, Emily Stein1, Dalit Ashany2 and Susan Goodman3, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Scarsdale, NY, 3Hospital for Special Surgery, New York 10025, NY

    Background/Purpose: Axial spondyloarthritis (AxSpA) is characterized by abnormal bone formation and, paradoxically, bone loss accompanied by increased bone fragility and vertebral fracture risk. Tumor necrosis…
  • Abstract Number: 0218 • ACR Convergence 2024

    Incidental Findings on Whole Body 18F-FDG PET/CT in a Rheumatoid Arthritis Clinical Trial Population

    Christina Costeas1, Daniel Solomon2, Katherine Liao3, Jon Giles4, Joan Bathon5 and Jane Kang6, and the TARGET Trial Consortium, 1Columbia University Irving Medical Center, New York, NY, 2Brigham and Women's Hospital, Newton, MA, 3Brigham and Women's Hospital, Boston, MA, 4Cedars Sinai Medical Center, Los Angeles, CA, 5Columbia University, NEW YORK, NY, 6Columbia University Medical Center, New York, NY

    Background/Purpose: Performing whole body imaging inevitably reveals incidental findings in the majority of cases. A clinical trial was conducted to determine whether different treatment strategies…
  • Abstract Number: 0633 • ACR Convergence 2024

    Novel LINE-1 Reverse Transcriptase Inhibitors Can Suppress Type I Interferon Responses and Are Promising Therapeutics for Lupus

    Wenyan Miao1, Digna de Bruin2, Cedric Arisdakessian1, Jannik Rousel2, Jared Steranka1, Matthijs Moerland2, Eric Jacobson1, Mehrnaz Gharaee-Kermani3, Liyang Diao1, Craig Dobry3, Nafeeza Hafeez1, Brian Desrosiers1, J. Michelle Kahlenberg3, Heike Keilhack1, Robert Rissmann2, Keith M Wilcoxen1 and Tessa Niemeyer-van der Kolk2, 1Rome Therapeutics, Boston, MA, 2Centre for Human Drug Research, Leiden, Netherlands, 3University of Michigan, Ann Arbor, MI

    Background/Purpose: Long Interspersed Element-1 (LINE-1) retrotransposon encodes for two proteins, ORF1p and ORF2p. ORF1p is a chaperone protein while ORF2p contains reverse transcriptase (RT) and…
  • Abstract Number: 1092 • ACR Convergence 2024

    Chronic Kidney Disease Is Associated with Increased Glucose Uptake-associated Metabolic Activity of Visceral Adipose and Subcutaneous Adipose Tissue in Gout Patients

    Shunya Kaneshita1, Sho Fukui2, Soheil Niku3, KWANGHOON LEE4, Ernest Belezzuoli3, Robert Terkeltaub5 and Monica Guma6, 1UCSD, Miyazu city, Kyoto, Japan, 2Brigham and Women's Hospital, Brookline, MA, 3UCSD, La Jolla, 4UCSD, San Diego, CA, 5Retired, San Diego, CA, 6UCSD, La Jolla, CA

    Background/Purpose: Gout, a condition characterized by elevated uric acid levels, is linked to multiple complications, including coronary artery disease, hypertension, and type 2 diabetes mellitus.…
  • Abstract Number: 1567 • ACR Convergence 2024

    Systemic Sclerosis Is Associated with Sub-Clinical Abnormalities in Myocardial Energetics, Perfusion and Increased Fibrosis

    Chin Yit Soo1, Nicholas Jex2, Stefano Di Donato3, Lucy Elizabeth Thornton4, Vishal Kakkar5, Riccardo Bixio6, Raluca Tomoaia1, Thomas Anderton2, May Lwin2, Christel Kamani2, Amrit Chowdhary2, Henry Procter1, Sharmaine Thirunavukarasu1, Sindhoora Kotha2, Marilena Giannoudi2, Eylem Levelt2, Sven Plein1, Francesco Delgado6 and Lesley-Anne Bissell7, 1Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, England, United Kingdom, 2Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 31. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 41. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 5University of Leeds, Leeds, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 7Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Primary cardiac involvement in systemic sclerosis (SSc) is heterogenous, poorly defined and associated with significant cardiac morbidity and mortality. The underlying mechanism is not…
  • Abstract Number: 1962 • ACR Convergence 2024

    Utility of 18 FDG-PET/CT Scans in the Diagnosis of Polyarteritis Nodosa and Other Medium Vessel Vasculitis

    Nouran Eshak1, Kristina Yancey2, Felipe Martinez3, Lester Mertz1, carolyn mead harvey4, Kenneth Warrington5, Matthew Koster5 and Megan Sullivan1, 1Mayo Clinic Arizona, Scottsdale, AZ, 2Mayo Clinic Arizona, Phoenix, AZ, 3Mayo Clinic Arizona, Phoenix, 4Mayo Clinic Florida, Jacksonville, FL, 5Mayo Clinic, Rochester, MN

    Background/Purpose: Medium vessel vasculitis (MVV), including polyarteritis nodosa (PAN), presents significant diagnostic challenges with patients frequently exhibiting non-specific systemic manifestations. While 18F-fluorodeoxyglucose PET/CT (PET/CT) is…
  • Abstract Number: 2136 • ACR Convergence 2024

    Distal Radius Correlation with Femur and Lumbar Spine T-scores: A Comprehensive Analysis

    Monder Lafi1, Hamzah Amin2, Muhammed Aqib Khan3 and Marwan Bukhari4, 1LANCASTER UNIVERSITY, Liverpool, United Kingdom, 2Lancaster University, Lancaster, United Kingdom, 3Lancaster Medical School, Lancaster, United Kingdom, 4University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom

    Background/Purpose: Osteoporosis, defined by the WHO as a BMD reduction of 2.5 standard deviations below that of a young healthy adult, is a major public…
  • Abstract Number: 0220 • ACR Convergence 2024

    Ultrasound-assessed Dactylitis as a Biomarker in the Early Diagnosis of Psoriatic Arthritis

    Otto Olivas-Vergara1, Raquel Largo2, Lina Martínez-Estupiñán3, Fredeswinda Romero-Bueno4, Olga Sánchez-Pernaute3, Javier R. Godo3, Maria del Carmen Fariña-Sabaris5, Belen Ruffin Vicente5, Carmen Herencia6, Aránzazu Mediero2, Agustina Criado Alcazar7, Pablo E. Borges1, Sheila Recuero-Díaz1, Andrea Alvear-Torres3, Amalia Gil3, Antía García-Fernández3, Ana Elena Hoyo Fernandez8, M. Isabel Sanchez-Barba8, M. Belen Ortega Trompeta8, Cristina Vazquez-Carballo9, Gabriel Herrero-Beaumont3 and ESPERANZA NAREDO10, 1Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD, Madrid, Spain, 2Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, Madrid, Spain, 3Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 4Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 5Department of Dermatology.Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 6Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, M, Spain, 7Primary Care..Centro de Salud Paseo Imperial, Madrid, Spain, 8Primary Care.Centro de Salud Paseo Imperial, Madrid, Spain, 9Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz. Autonomous University of Madrid, Madrid, Spain, 10Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain

    Background/Purpose: The primary objective of this prospective, longitudinal, observational study was to evaluate the predictive value of ultrasound (US)-detected elementary lesions of dactylitis together with…
  • Abstract Number: 0643 • ACR Convergence 2024

    Using FDG PET Brain Scans and Deep Learning Analyses to Identify a Specific Network Correlated with Cognitive Impairment in SLE

    Nha Nguyen1, An Vo1, Chris Tang1, Erik Anderson2, Cynthia Aranow2, Betty Diamond3, David Eidelberg1 and Meggan Mackay4, 1Feinstein Institutes, Manhasset, NY, 2Feinstein Institutes for Medical Research, New York, NY, 3The Feinstein Institutes for Medical Research, Manhasset, NY, 4Feinstein Institutes for Medical Research, Manhasset, NY

    Background/Purpose: Cognitive impairment (CI) is a debilitating, untreatable problem for up to 80% of individuals with SLE and human and mouse data suggest multiple SLE-related…
  • Abstract Number: 1100 • ACR Convergence 2024

    Coronary Dual-Energy Computed Tomography for the Detection of Monosodium Urate Crystal Deposition in the Arteries of Individuals with and Without Gout (CORODECT): A Multi-Center Prospective Imaging Study

    Chio Yokose1, Tristan Pascart2, Mangun Randhawa3, Padraic Kennedy4, Christoph Schwabl5, saiajay chigurupati3, Bohang Jiang3, Leo Lu6, Julia Held5, Gerlig Widmann5, F. Joseph Simeone3, Brian Ghoshhajra3, Adnan Sheikh4, Kamran Shojania4, Gudrun Feuchtner5, Andrea Klauser5, Savvas Nicolaou4, Jean-François Budzik2, Fabio Becce7 and Hyon K. Choi8, 1Massachusetts General Hospital, Waltham, MA, 2Lille Catholic University, Lille, France, 3Massachusetts General Hospital, Boston, MA, 4Vancouver General Hospital, Vancouver, Canada, 5Medical University Innsbruck, Innsbruck, Austria, 6Arthritis Research Canada, Vancouver, BC, Canada, 7Lausanne University Hospital (CHUV), Lausanne, Switzerland, 8Massachusetts General Hospital, Lexington, MA

    Background/Purpose: Prior dual-energy CT (DECT) studies have suggested that monosodium urate (MSU) crystals may be present in the coronary arteries of patients with gout. However,…
  • Abstract Number: 1588 • ACR Convergence 2024

    Validation of a Lung Ultrasound Interpretation Criteria for Interstitial Lung Disease Screening in Systemic Sclerosis and Inflammatory Myopathy

    Robert Fairchild1, Diane Mar2, Mariani Deluna3, Henry Guo3, David Fiorentino4 and Lorinda Chung5, 1Stanford University, San Francisco, CA, 2VA Palo Alto / Stanford, Palo Alto, CA, 3Stanford University, Palo Alto, CA, 4Stanford University, Menlo Park, CA, 5Stanford University, Woodside, CA

    Background/Purpose: Interstitial lung disease (ILD) is a common complication of connective tissue disease (CTD) with a high prevalence in SSc and inflammatory myopathy (IM). Early…
  • Abstract Number: 1964 • ACR Convergence 2024

    Comparison of Knee Minimum Joint Space Width Measurements Using Deep Learning in Patients with Rheumatoid Arthritis and Osteoarthritis Undergoing Total Knee Arthroplasty

    Kellen Mulford1, Elizabeth Kaji1, Austin Grove1, Ronnie Sebro2, Cody Wyles1, John Davis1 and Cynthia Crowson1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL

    Background/Purpose: While large joint damage is a hallmark of both Osteoarthritis (OA) and Rheumatoid Arthritis (RA), the mechanisms of degradation are substantially different. Minimum joint…
  • Abstract Number: 2208 • ACR Convergence 2024

    Clinical, Imaging and Treatment Characteristics of Patients with Progressive Systemic Autoimmune Rheumatic Disease-related Interstitial Lung Diseases (SARD-ILDs) in the ILD-PRO Registry

    Aparna Swaminathan1, Jeremy Weber2, Jamie Todd3, Scott Palmer3, Megan Neely3, Peide Li4 and Ann Chauffe5, and on behalf of the ILD-PRO Registry investigators, 1Duke Clinical Research Institute, Durham, North Carolina, USA; Duke University Medical Center, Durham, North Carolina, USA, Durham, NC, 2Duke Clinical Research Institute, Durham, NC, 3Duke Clinical Research Institute, Durham, North Carolina, USA; Duke University Medical Center, Durham, North Carolina, USA, Durham, 4Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA, Ridgefield, 5Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut, USA, Ridgefield, CT

    Background/Purpose: The ILD-PRO Registry is a multicenter US registry of patients with progressive fibrosing interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF). We…
  • Abstract Number: 0221 • ACR Convergence 2024

    The Significance of Tenderness with or Without Swelling of Finger Joints in Relation to Magnetic-resonance-imaging, Ultrasound and X-ray in Psoriatic Arthritis

    Victoria Furer1, iris Eshed2, Moshe iluz1, Ori Elkayam3 and Ari Polachek4, 1Tel-Aviv Medical Center, Tel-Aviv, Israel, 2Sheba Medical Center, Tel Hashomer affiliated with School of medicine, Tel Aviv University, Department of Diagnostic Imaging, Tel Aviv, Israel, 3Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 4Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel

    Background/Purpose: The musculoskeletal involvement in psoriatic arthritis (PsA) can involve both articular and extra articular structures manifested by inflammatory and structural lesions. The relationship between…
  • Abstract Number: 0696 • ACR Convergence 2024

    MRI DAVIX Index Is an Imaging Biomarker for Endothelial Damage of Systemic Sclerosis Digital Ulcers

    Stefano Di Donato1, Rebecca Ross2, Yassir El-Sherbiny3, Riccardo Bixio4, Marco Minerba5, Christopher Wasson6, Jun Li7, Jochen SCHMITZ8, Sudha Visvanathan9 and Francesco Del Galdo6, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 2Medicine and Health, University of Leeds, Leeds, United Kingdom, 3Nottingham Trent University, Nottingham, United Kingdom, 4University of Verona, Verona, Verona, Italy, 51. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 6University of Leeds, Leeds, United Kingdom, 7Boehringer Ingelheim, Danbury, CT, 8Boehringer-Ingelheim, Ridgefield, CT, 9Boehringer-Ingelheim Pharmaceuticals, Ridgefield, CT

    Background/Purpose: Circulating endothelial cells (CEC) and their precursors have been shown to correlate to the severity of vascular manifestations in Systemic sclerosis1, such as Digital…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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