Abstracts tagged "Imaging"

Abstract Number: 2293 • 2016 ACR/ARHP Annual Meeting
Cardiometabolic Risk and Subclinical Urate Deposits in Patients with Symptomatic Hyperuricemia and Metabolic Syndrome
Seoyoung C. Kim¹, Rajesh Garg², Stacy Smith³, Alyssa Wohlfahrt⁴, Anarosa Campos⁵, Kathleen Vanni⁴, Lauren K Lee⁶, Penny Wang⁶, Zhi Yu⁷, Marcelo Di Carli⁸ and Daniel H. Solomon⁹, ¹Rheumatology, Immunology and Allergy; Pharmacoepidemiologyand Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ²Endocrinology, Brigham & Women's Hospital, Boston, MA, ³Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, ⁸Div. of Nuclear Medicine, Brigham and Women's Hospital, Boston, MA, ⁹Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Elevated serum uric acid (sUA) levels, with and without gout, are associated with systemic inflammation, coronary artery disease (CAD), chronic kidney disease, and diabetes.…
Abstract Number: 875 • 2016 ACR/ARHP Annual Meeting
Pericardial Involvement in Biopsy-Proven Giant-Cell Arteritis (GCA) Patients Detected By CT Angiography (CTA): Prevalence at Diagnosis and Outcome with Glucocorticoid (GC) Treatment
Javier Marco-Hernández¹, Sergio Prieto-González², Rosa Gilabert³, Pedro Arguis⁴, Georgina Espígol-Frigolé⁵, Ana García-Martínez⁶, Ester Planas-Rigol⁵, Marc Corbera-Bellalta², Nekane Terrades-Garcia², Jose Hernández-Rodríguez² and Maria C. Cid⁷, ¹Internal Medicine, Hospital Clínic, Barcelona, Spain, ²Vasculitis Research Unit. Department of Autoimmune Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ³Center for Diagnostic Imaging, Hospital Clínic, Barcelona, Spain, ⁴Center for Diagnostic Imaging, Hospital Clínic. IDIBAPS. University of Barcelona, Barcelona, Spain, ⁵Department of Autoimmune and Systemic Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ⁶Emergeny Department, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain, ⁷Autoimmune and Systemic Diseases, Hospital Clínic. University of Barcelona. IDIBAPS, Barcelona, Spain
Background/Purpose: In GCA, cranial artery involvement is particularly frequent and underlies the classical manifestations and complications of the disease. Symptomatic pericarditis has been occasionally described…
Abstract Number: 3097 • 2016 ACR/ARHP Annual Meeting
Osteoclast Precursor Frequency and Imaging Findings Associated with Arthritis Onset in a Psoriasis Longitudinal Cohort
Ralf G. Thiele¹, Yahui Grace Chiu², Francisco Tausk³, Bethany A. Marston⁴, Changyong Feng⁵, Gregory Dieudonne⁶, Vaseem Chengazi⁶, Sharon Moorehead⁷, Debbie Campbell⁷ and Christopher T. Ritchlin⁸, ¹Medicine, University of Rochester Medical Center, Rochester, NY, ²Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, ³Dermatology, University of Rochester, Rochester, NY, ⁴Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁵Statistics, University of Rochester, Rochester, NY, ⁶Radiology, University of Rochester, Rochester, NY, ⁷Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, ⁸Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Psoriasis (Ps) precedes joint inflammation by an average of 10 years psoriatic arthritis (PsA) patients. Reports have demonstrated abnormal musculoskeletal imaging findings in psoriasis…
Abstract Number: 892 • 2016 ACR/ARHP Annual Meeting
FDG-PET CT Evaluation By Visual Grading Is Not Sufficiently Discriminative to Assess Disease Activity in Takayasu’s Arteritis Patients with ‘Persistent’ Disease
Ali Ugur Unal¹, Fuat Dede², Tanju Yusuf Erdil², Tunc Ones², Fatma Alibaz-Oner³ and Haner Direskeneli⁴, ¹Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ²Department of Nuclear Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey, ³Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: Takayasu arteritis (TAK) is a large-vessel vasculitis in which assessment of disease activity is challenging. Recent studies support that 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed…
Abstract Number: 3133 • 2016 ACR/ARHP Annual Meeting
Association Between Quantitatively Measured Infrapatellar Fat Pad High Signal Intensity Alteration and Knee Structural and Symptomatic Abnormalities in Patients with Symptomatic Knee Osteoarthritis
WEIYU HAN¹, Graeme Jones² and Changhai Ding², ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: Infrapatellar fat pad (IPFP), a local adipose tissue, may have important contributions to knee osteoarthritis (OA). IPFP signal intensity alterations on MRI may represent…
Abstract Number: 934 • 2016 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging (MRI) Joint Space Narrowing Is an Independent Predictor of Radiographic and MRI Damage Progression in Patients with Early Rheumatoid Arthritis
Signe Møller-Bisgaard¹, Bo Jannik Ejbjerg², Iris Eshed³, Kim Hørslev-Petersen⁴, Merete Lund Hetland^5,6, Anne Grethe Jurik⁷, Henrik S Thomsen⁸, Trine Torfing⁹, Kristian Stengaard-Pedersen¹⁰, Peter Junker¹¹, Niels Steen Krogh¹², Tine Lottenburger¹³, Torkell Ellingsen¹⁴, Lis Smedegaard Andersen¹⁵, Henrik Skjødt¹⁶, Anders Svendsen¹⁴, Ulrik Tarp¹⁰, Ib Tønder Hansen¹⁰, Jan Pødenphant¹⁵, Jens Kristian Pedersen¹⁴, Hanne Lindegaard¹⁴, Aage Vestergaard¹⁷, Daniel Glinatsi¹⁶ and Mikkel Østergaard¹⁶, ¹Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ²Department of Rheumatology, Slagelse University Hospital, Slagelse, Denmark, ³Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, ⁴King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵Danish Rheumatologic Biobank and DANBIO registry, Rigshospitalet, Glostrup, Gentofte and Herlev University Hospital, Copenhagen, Denmark, ⁶Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark,, Copenhagen, Denmark, ⁷Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁸Department of Radiology, Herlev University Hospital, Copenhagen, Denmark, ⁹Department of Radiology, Odense University Hospital, Odense, Denmark, ¹⁰Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ¹¹University of Southern Denmark, Odense, Denmark, ¹²ZiteLab ApS, Copenhagen, Denmark, ¹³Department of Medicine, Vejle Regional Hospital, Vejle, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁵Department of Rheumatology, Gentofte University Hospital, Gentofte, Denmark, ¹⁶Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, ¹⁷Department of Radiology, Hvidovre University Hospital, Denmark, Hvidovre, Denmark
Background/Purpose: Magnetic Resonance Imaging (MRI) osteitis and synovitis have been identified as predictors of structural damage progression in rheumatoid arthritis (RA)1,2, but the predictive value…
Abstract Number: 3177 • 2016 ACR/ARHP Annual Meeting
Targeted Nuclear Imaging for the Early Detection of Lung Involvement in Systemic Sclerosis
Janine Schniering¹, Stephanie Haller², Zhongning Guo¹, Martina Benesova^2,3, Carol A. Feghali-Bostwick⁴, Roger Schibli^2,3, Oliver Distler⁵, Cristina Müller^2,3 and Britta Maurer⁵, ¹Department of Rheumatology, University Hospital Zurich, Schlieren, Switzerland, ²Center for Radiopharmaceutical Sciences ETH-PSI-USZ, Paul Scherrer Institute, Villigen PSI, Switzerland, ³Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland, ⁴Medicine, Medical University of South Carolina, Charleston, SC, ⁵Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
Background/Purpose: Interstitial lung disease (ILD) is one of the main causes of systemic sclerosis (SSc)-related deaths. Since routine diagnostics such as high resolution computed tomography…
Abstract Number: 1276 • 2016 ACR/ARHP Annual Meeting
Sensitive SPECT/CT Imaging of Fibroblast Activation Protein Expression after Anti-IL-22 Treatment in Experimental Arthritis
Debbie M. Roeleveld¹, Tessa van der Geest², Birgitte Walgreen¹, Monique M. Helsen¹, Tapan K. Nayak³, Christian Klein⁴, Martin Hegen⁵, Peter Laverman², Otto C. Boerman² and Marije I. Koenders¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Radiology & Nuclear Medicine, Radboud university medical center, Nijmegen, Netherlands, ³Research & Early development, Roche Pharmaceutical, Basel, Switzerland, ⁴Research & Early Development, Roche Pharmaceutical, Schlieren, Switzerland, ⁵Immunoscience Research Unit, Pfizer, Cambridge, MA
Background/Purpose: Rheumatoid arthritis (RA) synovial tissue has been demonstrated to express high levels of fibroblast activation protein (FAP) using anti-FAP-antibody 28H1. In addition, RA patients…
Abstract Number: 1279 • 2016 ACR/ARHP Annual Meeting
Imaging of Ankylosing Spondylitis By [18f]Fluoride PET-CT to Assess Bone Formation Activity and to Monitor Anti-TNF Therapy
Stefan Bruijnen¹, Nicki Verweij², Leonie van Duivenvoorde³, Dominique Baeten⁴, Christiaan van Denderen⁵, Joost Bot⁶, Otto Hoekstra⁷, Pieter Raijmakers⁶, Irene van der Horst - Bruinsma⁸ and Conny van der Laken², ¹Dept. of Rheumtaology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ²Dept. of Rheumatology, Amsterdam Rheumatology and immunology Center - location VU University Medical Center, Amsterdam, The Netherlands, Amsterdam, Netherlands, ³Amsterdam Rheumatology and immunology Center, Academic Medical Center, Amsterdam, Netherlands, ⁴Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, ⁵READE, Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, ⁶Department of Radiology & Nuclear Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁷Nuclear medicine and PET research, VU University Medical Center, Amsterdam, Netherlands, ⁸Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands
Background/Purpose: Bone formation is an important hallmark of ankylosing spondylitis (AS). Recently, we demonstrated that axial bone formation activity in AS patients can be visualized…
Abstract Number: 1281 • 2016 ACR/ARHP Annual Meeting
Feasibility and Reliability of the Spondyloarthritis Research Consortium of Canada Sacroiliac Joint Inflammation Score for Children with Spondyloarthritis
Nancy A. Chauvin¹, Walter P. Maksymowych^2,3, Robert G. Lambert⁴, Jacob Jaremko⁵, David M. Biko¹, Timothy G. Brandon⁶, Joel Paschke² and Pamela F. Weiss^7,8, ¹Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ²CaRE Arthritis, Edmonton, AB, Canada, ³Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ⁸Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: We lack a method to quantify severity of inflammation in the pediatric sacroiliac joint. We evaluated the reliability and construct validity of the Spondyloarthritis…
Abstract Number: 1324 • 2015 ACR/ARHP Annual Meeting
Simplified Larsen Erosion Score Is Compatible with the Classic Larsen Score but Less Time Consuming in Practice
Michael Ziegelasch¹, Alf Kastbom², Thomas Skogh³, Kristina Forslind⁴ and Alf Kastbom, ¹Rheumatology Department, Rheumatology/AIR, Linkoping, Sweden, ²Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, ³IKE/Rheumatology, Linköping University, Linköping, Sweden, ⁴Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden
Background/Purpose: Untreated rheumatoid arthritis (RA) often leads to joint space narrowing (JSN) and erosions in synovial joints. Scoring systems like Sharp van der Heijde and…
Abstract Number: 2405 • 2015 ACR/ARHP Annual Meeting
Knee Sounds May Predict Osteoarthritis Severity, Symptoms and Function: Pilot Investigation Toward a Novel Dynamic Imaging System
Victoria Manning¹, Costas Yiallourides², Mads Brevadt¹, Alastair Moore², Edouard Auvinet¹, Patrick Naylor² and Justin Cobb¹, ¹Musculoskeletal Lab, Imperial College London, London, United Kingdom, ²Communications and Signal Processing Group, Imperial College London, London, United Kingdom
Background/Purpose: Knee sounds (KS) may provide a low-cost, risk-free means of identifying presence and severity of knee osteoarthritis (KOA). Unlike static imaging, KS during dynamic…
Abstract Number: 1327 • 2015 ACR/ARHP Annual Meeting
Five-Year Follow-up of Radiographic Sacroiliitis: Progression As Well As Improvement?
Alexandre Sepriano^1,2, Martin Rudwaleit³, Joachim Sieper^4,5, Rosaline van den Berg⁶, Robert B. M. Landewé⁷ and Désirée van der Heijde⁸, ¹Rheumatology, Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands, Leiden, Netherlands, ²Rheumatology, Hospital de Egas Moniz - CHLO, Lisbon, Portugal, Lisbon, Portugal, ³Rheumatology, Dept of Medicine, Charité - Campus Benjamin Franklin, Berlin, Germany, Berlin, Germany, ⁴German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ⁵Rheumatology, Charité - Campus Benjamin Franklin, Berlin, Germany, Berlin, Germany, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁸University Hospital, Maastricht, Netherlands
Background/Purpose: Detecting sacroiliitis on plain pelvic X-rays is known to be difficult, resulting in large variability regarding presence/absence of radiographic sacroiliitis. In addition, the number…
Abstract Number: 3255 • 2015 ACR/ARHP Annual Meeting
Brain White Matter Integrity: A Future Biomarker for Rheumatoid Arthritis Related Fatigue?
Neil Basu¹, Marayam Alsyedalhashem², Mariella D'Allesandro³, Alison D. Murray², Daniel J. Clauw⁴ and Gordon D. Waiter², ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ³Muscloskeletal Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Fatigue is a major burden among patients with rheumatoid arthritis (RA). The identification of reliable biomarkers would greatly enhance research in this challenging field. …
Abstract Number: 1336 • 2015 ACR/ARHP Annual Meeting
To PET or Not to PET in General Rheumatology Practice
Kavina Shah, Roshni Doshi, Joshua Balogun-Lynch, Henry Penn and Shahir Hamdulay, Rheumatology, Northwick Park Hospital, Middlesex, United Kingdom
Background/Purpose: Fluoro-deoxy-glucose positron emission tomography with computerised tomography (PET/CT) is an imaging modality which identifies tissues with high metabolic activity. It is used in the…

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