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Abstracts tagged "Imaging"

  • Abstract Number: 131 • 2016 ACR/ARHP Annual Meeting

    Analysis of Correlation and Causes for Discrepancy Between Quantitative and Semi Quantitative Doppler Scores in Synovitis in Rheumatoid Arthritis

    Hamed Rezaei1,2,3, Erik af Klint4, Hilde B. Hammer5, Lene Terslev6, MA d'Agostino7,8, Yogan Kisten3 and Laurent Arnaud9, 1Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden, 2The Karolinska Institute, Stockholm, Sweden, 3Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, 4Medicine, Rheumatology Unit, Department of Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden, 5Dept. of Rheumtology, Diakonhjemmet Hospital, Oslo, Norway, 6Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, 7Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, 8Department of Rheumatology, Ambroise Paré Hospital, Boulogne-Billancourt, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital, Boulogne-Billancourt, Paris, France, Paris, France, 9Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Dept. of Medicine, Karolinska institutet, Stockholm, Sweden

    Background/Purpose:  Doppler ultrasound plays an increasing role for monitoring disease activity in rheumatoid arthritis (RA). This study aimed to evaluate the association between two semi-quantitative…
  • Abstract Number: 1289 • 2016 ACR/ARHP Annual Meeting

    Comparison of Clinical Parameters and PET/MRI in Juvenile Idiopathic Arthritis

    Kathleen Jo Corbin1, Emily von Scheven1, Youngho Seo2, Spencer Behr2 and John MacKenzie3, 1Division of Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 2Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, 3Section of Pediatric Radiology, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Positron emission tomography (PET) can be used to identify inflammation using 18F-fluorodeoxyglucose (18F-FDG).  18F-FDG uptake correlates with clinical and laboratory markers of disease activity…
  • Abstract Number: 135 • 2016 ACR/ARHP Annual Meeting

    The 8-Joint Ultrasound Score Is a Useful Marker for Monitoring Therapeutic Response in Rheumatoid Arthritis

    Ryusuke Yoshimi1, Yukihiro Toyota1, Naomi Tsuchida1, Yumiko Sugiyama1, Yosuke Kunishita1, Daiga Kishimoto1, Reikou Kamiyama1, Kaoru Minegishi2, Maasa Tamura1, Yukiko Asami1, Yohei Kirino1, Shigeru Ohno2 and Hideaki Nakajima1, 1Department of Hematology and Clinical Immunology, Yokohama City University School of Medicine, Yokohama, Japan, 2Center for Rheumatic Disease, Yokohama City University Medical Center, Yokohama, Japan

    Background/Purpose: Musculoskeletal ultrasonography (US) is one of the standard tools for the diagnosis and monitoring of rheumatoid arthritis (RA). Although we and other groups have…
  • Abstract Number: 1296 • 2016 ACR/ARHP Annual Meeting

    Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion Volume in Knee Osteoarthritis

    Lena Franziska Schaefer1, Ming Yin1, Meera Sury2, Scott Jamieson1, Jamie E. Collins3, Stacy Smith4 and Jeffrey Duryea1, 1Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, 2Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, 3Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, 4Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA

    Quantitative Measurements of Cartilage, Osteophyte, and Bone Marrow Lesion volume in Knee Osteoarthritis Schaefer L.F., Yin M., Sury, M., Jamieson S., Collins J., Smith S.,…
  • Abstract Number: 162 • 2016 ACR/ARHP Annual Meeting

    Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative

    Gwenael Guillard1, Graham R. Vincent1, Philip G. Conaghan2, Alan Brett3 and Michael A Bowes1, 1Imorphics Ltd, Manchester, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 3Imorphics Ltd, MANCHESTER, United Kingdom

    Automated Segmentation of Cartilage Provides Comparable Accuracy and Better Responsiveness Than Manual Segmentation: Data from the Osteoarthritis Initiative *Guillard G., *Vincent G.R., *Brett, A., **Conaghan,…
  • Abstract Number: 1304 • 2016 ACR/ARHP Annual Meeting

    2D and 3D Measurements of Osteoarthritis Joint Space Width Have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from the Osteoarthritis Initiative

    Aaron Ray1, Michael A Bowes2, Bright Dube1, Elizabeth M.A. Hensor1, Andrew J Barr1 and Philip G. Conaghan1, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2Imorphics Ltd, Manchester, United Kingdom

    2D and 3D Measurements of Osteoarthritis Joint Space Width have Good Agreement in Radiographically Normal Knees but Poor Agreement with Advancing Kellgren-Lawrence Grade: Data from…
  • Abstract Number: 169 • 2016 ACR/ARHP Annual Meeting

    Ultrasound and Magnetic Resonance Imaging Fusion of Images and B-Flow Evaluation of Tenosynovitis  – a Pilot Study on New Imaging Techniques in Rheumatoid Arthritis Patients

    Mads Ammitzbøll-Danielsen1,2, Daniel Glinatsi2,3, Søren Torp-Pedersen4, Esperanza Naredo5, Mikkel Ostergaard2 and Lene Terslev6, 1Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark, 2Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, 3Center for Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Glostrup, Denmark, 4Department of Diagnostics, Rigshospitalet, Glostrup, Copenhagen, Denmark, 5Rheumatology, Hospital General Universitario Gregorio Marañón and Universidad Complutense, Madrid, Spain, 6Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Copenhagen Center for Arthritis Research (COPECARE), Copenhagen, Denmark

      Background/Purpose: Image fusion is an advanced imaging technology, which enables fusion of ultrasound (US) and magnetic resonance imaging (MRI). This fusion gives for each…
  • Abstract Number: 1328 • 2016 ACR/ARHP Annual Meeting

    Infective Endocarditis with Septic Arthritis: A Single-Center Experience

    Sarah B. Lieber1, Robert Shmerling2, Andy Moore3, Mary Louise Fowler4, Kunwal Nasrullah5 and Ziv Paz1, 1Beth Israel Deaconess Medical Center, Boston, MA, 2Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA, 3Division of Rheumatology, Cambridge Health Alliance, Harvard Medical School, Boston, MA, 4Boston University School of Medicine, Boston, MA, 5Boston University Medical School, BOSTON, MA

    Background/Purpose: Echocardiogram is frequently performed on patients presenting with septic arthritis (SA) but rarely demonstrates evidence of infective endocarditis (IE). Similarly, while patients with IE…
  • Abstract Number: 173 • 2016 ACR/ARHP Annual Meeting

    S100A8/A9, a Potent Serum and Molecular Imaging Biomarker for Synovial Inflammation and Joint Destruction in Seronegative Experimental Arthritis

    Edwin J. W. Geven1, Martijn H. J. van den Bosch1, Shahla Abdolahi-Roodsaz1, Annet W. Sloetjes1, Sven Hermann2, Michael Schäfers2, Marije I. Koenders1, Dirk Föll3, Johannes Roth4, Thomas Vogl4 and Peter L. E. M. van Lent1, 1Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 2European Institute for Molecular Imaging, University of Münster, Münster, Germany, 3Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, 4Institute of Immunology, University of Münster, Münster, Germany

    Background/Purpose: Seronegative joint diseases, including psoriatic arthritis and juvenile idiopathic arthritis, are characterized by the lack of autoantibodies, which are relevant biomarkers for predicting disease…
  • Abstract Number: 1444 • 2016 ACR/ARHP Annual Meeting

    Differential Expression of Wnt Inhibitors before and after Joint Inflammation Onset in Rat Arthritis Could Partly Explain Paradoxical Effect of Sclerostin Inhibition

    Guillaume Courbon1, Raphaelle Lamarque2, Marie-Thérèse Linossier2, Norbert Laroche2, Thierry Thomas3, Laurence Vico2 and Hubert Marotte3, 1SAINBIOSE INSERM U1059, University of Lyon, Saint-Etienne, France, 2SAINBIOSE INSERM U1059, University of Lyon, Saint Etienne, France, 3SAINBIOSE INSERM U1059 and Rheumatology department, University of Lyon and University Hospital of Saint Etienne, Saint Etienne, France

    Background/Purpose:  Periarticular bone loss in rheumatoid arthritis is considered to be mainly related to synovial inflammation, leading to uncoupling between decreased bone formation and increased…
  • Abstract Number: 257 • 2016 ACR/ARHP Annual Meeting

    CNS Manifestations of Patients with Muckle-Wells Syndrome

    sara Sebnem KILIC1, sukru cekic2 and Juan Aróstegui3, 1Pedaitric Rheumatology, Prof Dr, Bursa, Turkey, 2Dr, Bursa, Turkey, 3Prof, Barcelona, Spain

    Background/Purpose: CAPS is a rare autoinflammatory disease associated with mutations in the NLRP3 gene that result in overactivation of the inflammasome, increased secretion of IL-1beta…
  • Abstract Number: 1577 • 2016 ACR/ARHP Annual Meeting

    An Investigation of Translocator Protein As a Tissue and Peripheral Blood Biomarker of Inflammation in Rheumatoid Arthritis

    Nehal Narayan1, Francesco Carlucci2 and Peter C. Taylor3, 1Rheumatology, University of Oxford, Oxford, United Kingdom, 2The Botnar Research Centre, University of Oxford, oxford, United Kingdom, 3Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom

    Background/Purpose: Translocator protein (TSPO) is a mitochondrial cholesterol transporter, utilised in diseases as a Positron Emission Tomography (PET) imaging marker of macrophage infiltration. Recent observations…
  • Abstract Number: 678 • 2016 ACR/ARHP Annual Meeting

    Additional Information from CT or MRI Imaging Can Increase Rheumatologists’ Consensus on Grading Sacroiliitis By Radiography: Results of the Trimage Project

    Nigil Haroon1, Xenofon Baraliakos2, Anne Grethe Jurik3, Gercek Can4, Ali Balcı5, Muhammet Cinar6, Ediz Dalkilic7, Salim Donmez8, Omer Nuri Pamuk9, Yavuz Pehlivan10, Salih Pay11, Handan Yarkan12, Gokce Kenar13 and Nurullah Akkoc13, 1Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, 4Department of Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 5Radiology, Dokuz Eylul University, Izmir, Turkey, 6Division of Rheumatology, Gülhane Military Medical Academy, School of Medicine, Ankara, Turkey, 7Department of Rhematology, Uludag University Faculty of Medicine, Bursa, Turkey, 8Department of Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, 9Rheumatology, Trakya University Faculty of Medicine, Edirne, Turkey, 10Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, 11Rheumatology, Yüksek Ihtisas University, Special Koru Hospital, Ankara, Turkey, 12Rheumatology, Dokuz Eylul University Faculty of Medicine, İzmir, Turkey, 13Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey

    Background/Purpose:  The diagnosis of ankylosing spondylitis (AS) is anchored on definitive changes of sacroiliits by radiography. This is relevant not only to clinical diagnosis, but…
  • Abstract Number: 1720 • 2016 ACR/ARHP Annual Meeting

    Predictive Value of Different Tools for Detection of Psoriatic Arthritis in Patients with Psoriasis in Daily Routine Care Using Questionnaires for Diagnosis of Psoriatic Arthritis and Fluorescence-Optical Imaging Technique

    Michaela Koehm1, Tanja Rossmanith2, Hans-Eckhard Langer3, GR Burmester4, Siegfried Wassenberg5, Benjamin Köhler6, Ulrich Kaesser7, Marina Backhaus8, Harald Burkhardt9 and Frank Behrens9, 1Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt/Main, Germany, 2Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Frankfurt, Germany, 3RHIO (Rheumatology, Immunology, Osteology) Duesseldorf, Duesseldorf, Germany, 4Charité – University Medicine Berlin, Berlin, Germany, 5Rheumazentrum, Ratingen, Germany, 6Rheumazentrum Ratingen, Ratingen, Germany, 76Internistische Praxisgemeinschaft am Krankenhaus Balserische Stiftung Gießen, Gießen, Germany, 8Rheumatology, Park-Klinik Weissensee, Berlin, Germany, 9Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt, Germany

    Background/Purpose: Psoriasis (Pso) is one of the most common chronic inflammatory skin disease in Europe. Psoriatic arthritis (PsA) is closely associated to Pso; the skin…
  • Abstract Number: 863 • 2016 ACR/ARHP Annual Meeting

    Arterial Lesions in Giant Cell Arteritis

    Tanaz A. Kermani1, Sehriban Diab2, Antoine Sreih3, David Cuthbertson4, Renee Borchin5, Simon Carette6, Lindsy J. Forbess7, Gary S. Hoffman8, Curry L. Koening9, Carol A. McAlear10, Paul A. Monach11, Larry W. Moreland12, Christian Pagnoux13, Philip Seo14, Robert F. Spiera15, Kenneth J. Warrington16, Steven R. Ytterberg17, Carol A. Langford18, Nader A. Khalidi19 and Peter A. Merkel20, 1Rheumatology, University of California Los Angeles, Santa Monica, CA, 2St. Joseph’s Healthcare, McMaster University, Hamilton, ON, Canada, 3Department of Rheumatology, University of Pennsylvania, Philadelphia, PA, 4Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, FL, 5University of South Florida, Tampa, FL, 6Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 7Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 8Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, 9Rheumatology, University of Utah, Salt Lake City, UT, 10University of Pennsylvania, Philadelphia, PA, 11Rheumatology, Boston University School of Medicine, Boston, MA, 12Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 13Division of Rheumatology, Mount Sinai Hospital, University Health Network, University of Toronto, Toronto, Canada, Toronto, ON, Canada, 14Medicine, Johns Hopkins University, Baltimore, MD, 15Hospital for Special Surgery, Cornell, New York, NY, 16Rheumatology, University of California Los Angeles, CA, USA Mayo, Rochester, MN, 17Rheumatology, Mayo Clinic, Rochester, MN, 18Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 19Division of Rheumatology, St. Joseph’s Health Care, McMaster University, Hamilton, ON, Canada, 20Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

       Background/Purpose: This study aimed to describe large arterial lesions among patients with giant cell arteritis (GCA) and to understand what clinical characteristics are associated…
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