Abstracts tagged "Imaging"

Abstract Number: 2150 • 2014 ACR/ARHP Annual Meeting
The Craniocervical Junction in Ankylosing Spondylitis: A Computed Tomography Based Study
Gleb Slobodin¹, Arsen Shpigelman², Hanna Dawood³, Doron Rimar⁴, Simona Croitoru³, Nina Boulman⁴, Michael Rozenbaum⁴, Lisa Kaly¹, Itzhak Rosner¹ and Majed Odeh³, ¹Rheumatology, Bnai Zion Medical Center, Haifa, Israel, ²Orthopedic Surgery, Bnai Zion Medical Center, Haifa, Israel, ³Bnai Zion Medical Center, Haifa, Israel, ⁴Rheumatology, Bnai Zion Medical Center / Technion Faculty of Medicine, Haifa, Israel
Background/Purpose Available studies of craniocervical junction (CCJ) involvement in ankylosing spondylitis (AS) are based on conventional radiography, which has limited ability in the definition of…
Abstract Number: 908 • 2014 ACR/ARHP Annual Meeting
Ultrasound-Detected Tenosynovitis Independently Associates with Flare in Patients with Rheumatoid Arthritis in Clinical Remission
Emanuela Bellis¹, Greta Carrara², Carlo Alberto Scirè², Alessandra Bortoluzzi³, Alberto Batticciotto⁴, Antonella Adinolfi⁵, Giovanni Cagnotto⁶, Marta Caprioli⁷, Marco Canzoni⁸, Francesco Cavatorta⁹, Fulvia Ceccarelli¹⁰, Orazio De Lucia¹¹, Valentina Di Sabatino¹², Antonella Draghessi¹³, Georgios Filippou¹², Ilaria Farina³, Maria Cristina Focherini¹⁴, Paola Frallonardo¹⁵, Alessandra Gabba¹⁶, Angelica Gattamelata¹⁰, Marwin Gutierrez¹³, Luca Idolazzi¹⁷, Filippo Luccioli¹⁸, Pierluigi Macchioni¹⁹, Marco Massarotti²⁰, Claudio Mastaglio²¹, Luana Menza²¹, Giulia Mirabelli¹⁸, Maurizio Muratore²², Simone Parisi²³, Valentina Picerno¹², Matteo Piga²⁴, Roberta Ramonda²⁵, Bernd Raffeiner²⁶, Daniela Rossi²⁷, Paola Rossini²⁸, Garifallia Sakellariou^29,30, Crescenzio Scioscia³¹, Carlo Venditti³², Annamaria Iagnocco¹⁰ and Marco Matucci-Cerinic³³, ¹Rheumatology, Ospedale Mauriziano, Turin, Italy, ²Italian Society for Rheumatology, Milan, Italy, ³A.O.U. S.Anna di Cona, Ferrara, Italy, ⁴L.Sacco University Hospital, Milan, Italy, ⁵Policlinico le Scotte, Siena, Italy, ⁶IRCCS Policlinico San Matteo, Pavia, Italy, ⁷Istituto di Cura Città di Pavia, Pavia, Italy, ⁸A.O. Sant'Andrea, Rome, Italy, ⁹A.O.U.P. Santa Chiara, Trento, Italy, ¹⁰Sapienza University of Rome, Rome, Italy, ¹¹Rheumatology, Orthopedic Institute Gaetano Pini, Milano, Italy, ¹²University of Siena, Siena, Italy, ¹³Università Politecnica delle Marche, Jesi, Italy, ¹⁴Ospedale Infermi, Rimini, Italy, ¹⁵Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ¹⁶A.O.U. di Cagliari, Cagliari, Italy, ¹⁷Ospedale Civile Maggiore, Verona, Italy, ¹⁸University of Perugia, Perugia, Italy, ¹⁹Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ²⁰Istituto Clinico Humanitas, Rozzano, Italy, ²¹Moriggia-Pelascini, Gravedona, Italy, ²²Department of Rheumatology, Hospital Galateo, San Cesario di Lecce, Italy, ²³A.O. Città della Salute e della Scienza di Torino, Turin, Italy, ²⁴Unit and Chair of Rheumatology, University Hospital of Cagliari, Cagliari, Italy, ²⁵Rheumatology Unit, Department of Medicine, University of Padua, Padova, Italy, ²⁶Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Italy, ²⁷University of Turin, Turin, Italy, ²⁸P.O. “Destra Secchia”, Pieve di Coriano, Italy, ²⁹Division of Rheumatology, University of Pavia School of Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, ³⁰Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy, ³¹University of Bari, Bari, Italy, ³²A.O. Rummo, Benevento, Italy, ³³Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Background/Purpose Clinical remission is now an achievable goal in patients with rheumatoid arthritis (RA). Much has been done in order to better understand and define…
Abstract Number: 2133 • 2014 ACR/ARHP Annual Meeting
Efficacy of Tocilizumab Therapy in Patients with Rheumatoid Arthritis Based on FDG-PET/CT
Koichi Okamura¹, Yukio Yonemoto¹, Chisa Okura² and Kenji Takagishi¹, ¹Orthopaedic Surgery, Gunma University, Maebashi, Japan, ²Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan
Background/Purpose: A humanized anti-interleukin-6 receptor (anti-IL-6R) antibody, tocilizumab (TCZ), is one of the biologics and the C-reactive protein (CRP) level and erythrocyte sedimentation rate (ESR)…
Abstract Number: 828 • 2014 ACR/ARHP Annual Meeting
Extent of Urate Deposition in Asymptomatic Hyperuricemia and Symptomatic Gout: A Dual Energy Computed Tomography Study
Nicola Dalbeth¹, Meaghan House¹, Opetaia Aati¹, Paul Tan², Christopher Franklin², Anne Horne¹, Gregory Gamble¹, Lisa K. Stamp³, Anthony Doyle² and Fiona M. McQueen⁴, ¹Department of Medicine, University of Auckland, Auckland, New Zealand, ²University of Auckland, Auckland, New Zealand, ³University of Otago, Christchurch, New Zealand, ⁴Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
Background/Purpose: Recent studies have reported that ultrasound features of urate crystal deposition are present in some asymptomatic individuals with hyperuricemia, suggesting that subclinical urate deposition…
Abstract Number: 2136 • 2014 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Erosion Detection and Measurement in Longitudinal Datasets Using High-Resolution Peripheral Quantitative Computed Tomography
Stephanie Finzel¹, Cheryl Barnabe², Kathryn Stok³, A. Scharmga⁴, Andrew J. Burghardt⁵, Ellen-Margrethe Hauge⁶, Hubert Marotte⁷, Stephanie Boutroy⁸, Klaus Engelke⁹, Dominique Toepfer¹⁰, Sebastian Kraus¹¹, Roland Kocijan¹², Xiaojuan Li¹³ and J. de Jong⁴, ¹Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ³Hpi F 26, Worfgang-Paul Str. 1, ETH Zurich Institute for Biomechanics, Zurich, Switzerland, ⁴Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁵Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁶Reumatologisk Afdeling, Aarhus Universitetshospital, Aarhus C, Denmark, ⁷Rheumatology, University Hospital of Saint Etienne, Saint Etienne, France, ⁸INSERM U1033 and University of Lyon, Hôpital Edouard Herriot, Lyon, France, ⁹Henkestr. 91, Institute of Medcial Physics Synarc, Hamburg, Germany, ¹⁰Institute of Medical Physics, University of Erlangen-Nuremberg, Erlangen, Germany, ¹¹Internal Medicine 3, Rheumatology and Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ¹²Medical Department II, St. Vincent Hospital, Vienna, Austria, ¹³Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose An operational case definition for identification of erosions imaged by HR-pQCT was achieved and tested in a first reliability exercise (RELEX-1) using cross-sectional data.…
Abstract Number: 797 • 2014 ACR/ARHP Annual Meeting
PET/CT for the Diagnosis of Giant Cell Arteritis: A Prospective Study
Alison Clifford¹, Elana Murphy¹, Steven Burrell², Matthew Bligh³, Godfrey Heathcote³, Mathieu Castonguay³, Kara Thompson⁴ and John G. Hanly⁵, ¹Rheumatology, Dalhousie University and Capital Health, Halifax, NS, Canada, ²Diagnostic imaging, Dalhousie University and Capital Health, Halifax, NS, Canada, ³Dalhousie University and Capital Health, Halifax, NS, Canada, ⁴Department of Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, ⁵Division of Rheumatology, Dalhousie University and Capital Health, Halifax, NS, Canada
Background/Purpose: Temporal artery (TA) biopsies are negative in up to 50% of patients with giant cell arteritis (GCA). In such cases, increased uptake in large…
Abstract Number: 1086 • 2013 ACR/ARHP Annual Meeting
The Straight Neck in Fibromyalgia
Robert S. Katz¹ and Anthony Farkasch², ¹Rush Medical College, Chicago, IL, ²Rheumatology Associates, Chicago, IL
Background/Purpose: In patients with fibromyalgia a straight neck is based on calculating the Cobb angle, a standard radiographic measurement, of lateral view radiographs of the…
Abstract Number: 2889 • 2013 ACR/ARHP Annual Meeting
Bone Marrow Edema and Structural Lesions In The Sacroiliac Joint In a Large Cohort Of Patients With Axial Spondyloarthritis, Chronic Low Back Pain and Healthy Controls
L. van Hoeven^1,2, J.J. Luime², P.D.M. de Buck³, J.M.W. Hazes² and A.E.a.M. Weel⁴, ¹Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, MC Haaglanden, Den Haag, Netherlands, ⁴Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands
Background/Purpose: MRI of the sacroiliac joint (SIJ) is included in the ASAS classification criteria for axial spondyloarthritis (axSpA) to identify patients at an earlier stage of…
Abstract Number: 863 • 2013 ACR/ARHP Annual Meeting
Romosozumab Administration Is Associated With Significant Improvements In Lumbar Spine and Hip Volumetric Bone Mineral Density and Content Compared With Teriparatide
H K Genant¹, S Boonen², M A Bolognese³, C Mautalen⁴, J P Brown⁵, C Recknor⁶, S Goemaere⁷, K Engelke⁸, Y-C Yang⁹, M Austin⁹, A Grauer⁹ and C Libanati⁹, ¹UCSF & Synarc Inc., San Francisco, CA, ²Leuven University Division of Geriatric Medicine, Leuven, Belgium, ³The Bethesda Health Research Center, Bethesda, MD, ⁴Centro de Osteopatias Medicas, Buenos Aires, Argentina, ⁵CHU de Québec Research Centre and Laval University, Québec, QC, Canada, ⁶United Osteoporosis Centers, Gainesville, GA, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Synarc Germany, Hamburg, Germany, ⁹Amgen Inc., Thousand Oaks, CA
Background/Purpose: Sclerostin is an osteocyte-derived inhibitor of osteoblast activity. Romosozumab, a monoclonal antibody to sclerostin stimulates bone formation and decreases bone resorption. In a phase…
Abstract Number: 2820 • 2013 ACR/ARHP Annual Meeting
Disease-Regulated Local Interleukin-10 Gene Therapy Diminishes Synovitis and Articular Cartilage Damage In Experimental Arthritis
Eline A. Vermeij¹, Mathijs G.A. Broeren¹, Miranda B. Bennink¹, Onno J. Arntz², Inger Gjertsson³, Wim B. van den Berg¹ and Fons A.J. van de Loo¹, ¹Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, Gothenburg, Sweden
Background/Purpose: Rheumatoid arthritis (RA) is a chronic destructive autoimmune disease and in most patients the disease follows an intermittent course with periods of exacerbation and…
Abstract Number: 615 • 2013 ACR/ARHP Annual Meeting
Relationship Between 25-Hydroxyvitamin D [25(OH)D] and Risk For Cardiovascular Events In Systemic Lupus Erythematosus Over 11 Years In An Inception Cohort
Apinya Lertratanakul¹, Peggy Wu², Alan Dyer¹, Dafna D. Gladman³, Murray B. Urowitz³, Paul R. Fortin⁴, Dominique Ibanez³, Rosalind Ramsey-Goldman⁵ and for the Systemic Lupus International Collaborating Clinics (SLICC)⁶, ¹Northwestern University, Chicago, IL, ²Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Medicine, Centre de Recherche du Chu de Québec et Université Laval, Quebec City, QC, Canada, ⁵Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Toronto Western Hospital, Division of Rheumatology, University of Toronto, Toronto Western Hospital (Coordinating Center), Toronto, ON, Canada
Background/Purpose: 25(OH)D deficiency has been associated with increased cardiovascular disease (CVD) in the general population. We investigated the relationship between 25(OH)D and CVD events in…
Abstract Number: 2801 • 2013 ACR/ARHP Annual Meeting
Comparative Longitudinal Analysis Of Periarticular Bone Structure In Patients Treated With Methotrexate In Combination Of Either TNF Blockers Or Tocilizumab
Sebastian Kraus¹, Matthias Englbrecht¹, Juergen Rech², Roland Kocijan¹, Georg A. Schett¹ and Stephanie Finzel¹, ¹Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ²Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany
Background/Purpose: Inhibition of tumor necrosis factor alpha (TNFi) and interleukin-6 receptor (IL6Ri, tocilzumab) are among the most potent therapeutic strategies in patients with rheumatoid arthritis…
Abstract Number: 307 • 2013 ACR/ARHP Annual Meeting
Abnormal Imaging and Increased Osteoclast Precursors In a Psoriasis Cohort Are Associated with New Onset of Psoriatic Arthritis
Ralf G. Thiele¹, Yahui Grace Chiu¹, Francisco A. Tausk², Bethany A. Marston¹, Gregory Dieudonne³, Vaseem Chengazi³, Michelle Smith¹, Sharon Moorehead¹, Rick Barrett¹ and Christopher T. Ritchlin¹, ¹Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ²Dermatology, University of Rochester, Rochester, NY, ³Radiology, University of Rochester, Rochester, NY
Background/Purpose: Psoriasis (Ps) precedes joint inflammation by about 10 years in patients who develop psoriatic arthritis (PsA). Several studies have documented abnormal musculoskeletal imaging findings…
Abstract Number: 2604 • 2013 ACR/ARHP Annual Meeting
Longitudinal Assessment Of Scleroderma Skin By Optical Coherence Tomography: Preliminary Validation Of Sensitivity To Change Over-Time
Giuseppina Abignano¹, Lesley-Anne Bissell¹, Jason Britton², Daniel Woods³, Maya H. Buch¹, Dennis McGonagle¹, Paul Emery¹ and Francesco Del Galdo¹, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ²Medical Physics Department, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ³Michelson Diagnostics Ltd, Kent, United Kingdom
Background/Purpose: Optical coherence tomography (OCT) has been shown to be a quantitative reliable tool to assess skin involvement in Systemic Sclerosis (SSc) (1). However the…
Abstract Number: 240 • 2013 ACR/ARHP Annual Meeting
Longitudinal Femorotibial Cartilage Thickness Increase In Young Athletes At The End Of Adolescence
Felix Eckstein¹, Heide Boeth², Gerd Diederichs³, Wolfgang Wirth¹, Martin Hudelmaier⁴, Sebastian Cotofana⁵ and Georg Duda⁶, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Center for Sports Science and Sports Medicine, Julius Wolff Institute, Charité – Universitätsmedizin Berlin, Berlin, Germany, ³Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Paracelsus Medical University, Salzburg, Austria, ⁵Musculoskeletal Anatomy, Paracelsus Medical University, Salzburg, Austria, ⁶Julius Wolff Institute, Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Anterior or posterior cruciate ligament (ACL/PCL) ruptures are thought to lead to early knee osteoarthritis (KOA) and thus considered scientifically valuable “models” of pre-radiographic…

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