Abstracts tagged "Imaging"

Abstract Number: 1213 • ACR Convergence 2025
Transitional Changes on High Resolution Computed Tomography (HRCT) in idiopathic inflammatory Myopathy- Associated Interstitial Lung Disease (IIM-ILD)
Sangmee Bae¹, Grace Kim², Jihey Lee², Daniela Markovic², Donald Tashkin², Jonathan Goldin², Rohit Aggarwal³ and Christina Charles-Schoeman⁴, ¹UCLA Rheumatology, Los Angeles, CA, ²UCLA, Los Angeles, ³University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA, ⁴UCLA Medical Center, Santa Monica, CA
Background/Purpose: HRCT is used as a surrogate for important histopathological findings when evaluating patients with interstitial lung disease (ILD). Quantitative imaging analysis (QIA) using CT…
Abstract Number: 0759 • ACR Convergence 2025
Distinct differences between giant cell arteritis diagnosed by fluorodeoxyglucose (FDG) positron emission tomography (PET) versus temporal artery biopsy-a comparative cohort study
Sehreen Mumtaz¹, Lerone Clark², Archit Srivastava², Hannah Langenfeld³, Andrew C. Hanson³, Cynthia Crowson⁴, Andy Abril², Nouran Eshak⁵, Megan Sullivan⁶, Matthew Koster³ and Kenneth Warrington³, ¹Mayo Clinic Florida, Jacksonville, FL, ²Mayo Clinic, Florida, Jacksonville, FL, ³Mayo Clinic, Rochester, MN, ⁴Mayo Clinic, Stewartvillle, MN, ⁵Mayo Clinic, Arizona, Scottsdale, AZ, ⁶Mayo Clinic Arizona, Scottsdale, AZ
Background/Purpose: Giant cell arteritis (GCA) is clinically heterogenous, and the presenting manifestations may influence diagnostic testing. The aim of this study was to evaluate the…
Abstract Number: 0227 • ACR Convergence 2025
Malignancy Screening of Dermatomyositis Patients in the Penn State Registry of Inflammatory Myopathies (PRIMO)
Katrina Gonzales¹, William DeKryger², Deepika Pugalenthi Saravanan², Esha Tulsian², Peri Newman³, Jacob Colello², Galen Foulke⁴ and Nancy Olsen⁵, ¹Penn State College of Medicine, Hummelstown, PA, ²Penn State College of Medicine, Hershey, PA, ³Penn State Health/ Penn State College of Medicine, Hershey, PA, ⁴Penn State Health, Hershey, PA, ⁵Penn State University/Milton S Hershey, Hershey, PA
Background/Purpose: Dermatomyositis (DM) is an immune-mediated myopathy characterized by muscle weakness and skin rash that carries an elevated risk of associated malignancy within 5 years…
Abstract Number: 2613 • ACR Convergence 2025
Ga-FAPI-04 PET/CT reveals increased fibroblast activation in synovial and enthesial tissues of psoriasis patients with arthralgia and predicts the development of psoriatic arthritis
Giulia Corte¹, Koray Tascilar², armin Atzinger³, Alp Temiz², Melek Yalcin Mutlu⁴, Rita Noversa de Sousa⁵, Maria Gabriella Raimondo⁶, Andreas Ramming⁷, Sara Bayat², Michael Sticherling⁸, Torsten Kuwert⁹, Christian Schmidkonz⁹, Georg Schett¹⁰ and Filippo Fagni¹¹, ¹- Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ²Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany, ³Department of Nuclear Medicine, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ⁴Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, erlangen, ⁵Department of Internal Medicine ³, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, ⁶Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, ⁷Department of Internal Medicine ³, Rheumatology & Immunology, Friedrich-Alexander-University (FAU) & Universitätsklinikum Erlangen, Erlangen, Germany, ⁸Department of Dermatology, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, ⁹Department of Nuclear Medicine, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, ¹⁰Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, ¹¹Department of Medicine ³ - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Bayern, Germany
Background/Purpose: 68Ga-FAPI-04 PET/CT reveals fibroblast activation in vivo and is increasingly used to assess rheumatic diseases, including inflammatory arthritides. (1,2) We previously demonstrated that the…
Abstract Number: 2081 • ACR Convergence 2025
Radiologic surveillance in the Phase II RCT of LEVI-04, a novel neurotrophin-3 inhibitor, in people with knee osteoarthritis: exclusions at screening
Ali Guermazi¹, Philip Conaghan², C Michael Perkins³, Claire Herholdt⁴, Iwona Bombelka⁵ and Simon Westbrook⁶, ¹Boston University, West Roxbury, MA, ²University of Leeds, Leeds, United Kingdom, ³Levicept, Sandwich, United Kingdom, ⁴Levicept Ltd, Ashtead, United Kingdom, ⁵Levicept, Sandwich, Kent, United Kingdom, ⁶Levicept Ltd, Sandwich, United Kingdom
Background/Purpose: LEVI-04 is a first-in-class fusion protein (p75NTR-Fc) that supplements the endogenous p75NTR binding protein, providing analgesia via inhibition of NT-3 activity. Like p75NTR, LEVI-04…
Abstract Number: 1951 • ACR Convergence 2025
Quantitative HRCT Analysis in Sjögren’s Disease-associated ILD: CALIPER-Derived Imaging Biomarkers for Prognostic Assessment
Gaetano La Rocca¹, Francesco Ferro², Vincenzo Uggenti³, Beatrice Dei⁴, Giovanni Fulvio⁴, Michele Moretti⁴, Marta Mosca⁵, Chiara Romei³ and Chiara Baldini⁵, ¹University of Pisa, Rheumatology Unit, Pisa, Pisa, Italy, ²Clinical and Experimental Medicine Department, Azienda Ospedaliero-Universitaria Pisana, Pisa, Pisa, Italy, ³University of Pisa, ²nd Radiology Unit, Pisa, Italy, ⁴Rheumatology Unit, University of Pisa, Pisa, Toscana, Italy, ⁵University of Pisa, Pisa, Pisa, Italy
Background/Purpose: Interstitial Lung Disease (ILD) is a frequent manifestation of Sjögren’s Disease (SjD), associated with significant morbidity and mortality. However, data on the prevalence of…
Abstract Number: 1664 • ACR Convergence 2025
Cardiac Sarcoidosis Response to Steroid-Sparing Immunosuppression
Alexia Zagouras¹, Sammy Pickell¹, Yuhan Liu¹, Ronald Witteles¹ and Matthew Charles Baker², ¹Stanford University, Stanford, CA, ²Stanford University, Menlo Park, CA
Background/Purpose: There are no FDA-approved therapies for cardiac sarcoidosis (CS), a disease associated with high morbidity and mortality. Treatment typically consists of glucocorticoids and off-label…
Abstract Number: 1205 • ACR Convergence 2025
Real-time MRI for assessment of swallowing impairment in inclusion body myositis and oculopharyngeal muscular dystrophy.
Rachel Zeng¹, Anke Rietveld², Omar Al-Bourini¹, Rosemarie HMJM Kroon², Arno Olthoff¹, Matthias Weidenmüller¹, Per-Ole Carstens¹, Isabel Kommerell¹, Saskia G Schütz¹, Corinne GC Horlings³, Johanna G Kalf³, Bert JM de Swart³, Baziel GM van Engelen², Tim Friede¹, Sabine Hofer¹, Jens Frahm⁴, Ali Seif Amir Hosseini¹, Jens Schmidt⁵ and Christiaan GJ Saris², ¹University Medical Center Göttingen, Göttingen, Germany, ²Radboudumc Research Institute for Medical Innovation, Nijmegen, Netherlands, ³Radboudumc Research Institute for Medical Innovation, Nijmegen, Germany, ⁴Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany, ⁵Immanuel University Hospital Rüdersdorf, Brandenburg Medical School, Rüdersdorf bei Berlin, Germany
Background/Purpose: Swallowing dysfunction -dysphagia- is a frequent and debilitating symptom in neuromuscular disorders, leading to malnutrition, cachexia, aspiration pneumonia and death. Identification of the underlying…
Abstract Number: 0755 • ACR Convergence 2025
Sex Differences in Subtypes of Vascular Involvement and Clinical Manifestations in Giant Cell Arteritis
Natalia Lopez Juanes, Carlota Ureta, Irene Monjo Henry, Maria-Eugenia Miranda-Carus, Chamaida Plasencia-Rodríguez and Eugenio de Miguel, Hospital Universitario La Paz, Madrid, Spain
Background/Purpose: Recognizing gender-specific differences in diseases is critical to improve diagnostic and therapeutic strategies. Giant cell arteritis (GCA) has been traditionally considered a predominantly female…
Abstract Number: 0186 • ACR Convergence 2025
Validation of Asynchronous Telehealth Visit for Adults and Children with Inflammatory Arthritis and Feasibility of Applying Thermal Imaging during Visits
Jenna Thomason¹, Rajdeep Pooni², Erin Sullivan³, Adriel Liau³, Sadie Van den Bogaerde¹, Iris Hamilton³, Sriya Paluvayi³, Megan Tran⁴, Janeth Robles-Navarro⁴, Ian Muse⁵, Audrey Luey⁴, Ava Klein³, Debosmita Biswas⁴, Savannah Partridge⁴, Tzielan Lee⁶, Alison Bays¹, Grant Hughes⁷, Elizabeth Ferucci⁸ and Yongdong (Dan) Zhao⁹, ¹University of Washington, Seattle, WA, ²Stanford University, Berkeley, CA, ³Seattle Children's Hospital, Seattle, ⁴University of Washington, Seattle, ⁵University of Washington, Department of Pediatrics, Seattle Children's Hospital, Seattle, ⁶Stanford University School of Medicine, Palo Alto, CA, ⁷University of Washington, Lynnwood, WA, ⁸Alaska Native Tribal Health Consortium, Anchorage, AK, ⁹Seattle Children’s Research Institute, Redmond, WA
Background/Purpose: Use of telemedicine has increased substantially. Our overall goal was to assess the utility of a standardized video joint exam and infrared thermal imaging…
Abstract Number: 2611 • ACR Convergence 2025
Exploring the Role of a Lung Ultrasound Score in the Assessment of Severity of Connective Tissue Disease-Related Interstitial Lung Disease
jin ding¹, ying zhang¹, Linxuan Pang¹, ning guo² and zhaohui zheng¹, ¹Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China (People's Republic), ²Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China (People's Republic)
Background/Purpose: The role of lung ultrasound (LUS) in assessing disease severity of interstitial lung disease (ILD) remains unclear. We employed a semiquantitative scoring system to…
Abstract Number: 1971 • ACR Convergence 2025
Intracranial Arterial Stenosis in Antiphospholipid Syndrome: A Neglected Vascular Involvement?
Yuying Fan¹, Jinyi Qian¹, Xiaohan Wei², Haoyu Pan¹, Shuyi Yu¹, Zhixia Yang¹, Shiyan Gu¹, Jianzhou Wu¹, Cenyi Wang¹, Tiancheng Zhou¹ and Hui Shi³, ¹Department of Rheumatology and Immunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Shanghai, Shanghai, China (People's Republic), ²Shanghai JiaoTong University, Shanghai, China (People's Republic), ³Shanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China (People's Republic)
Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by thrombotic events and obstetric complications. While macrovascular and microvascular manifestations have been increasingly acknowledged—particularly…
Abstract Number: 1950 • ACR Convergence 2025
Pericoronary fat enhancement in rheumatoid arthritis differs from controls and associates with coronary atherosclerosis independently of epicardial fat volume
Frederik Enevoldsen¹, Sarah Ormseth², Dzenan Masic¹, Matthew Budoff³, Ellen-Margrethe Hauge¹ and George Karpouzas³, ¹Aarhus University, Aarhus, Denmark, ²The Lundquist Institute for Biomedical Innovation, Torrance, CA, ³Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Pericoronary adipose tissue attenuation (PCATa) reflects the composition of the fat directly surrounding the coronary arteries and is associated with coronary wall inflammation. In…
Abstract Number: 1632 • ACR Convergence 2025
PET/CT-Based Distribution of Arterial Involvement and Its Association With Clinical Outcomes in Takayasu Arteritis
Tokio Katakura¹, Tsuyoshi Shirai², Kentaro Mori¹, Mikihiro Takahashi¹, Yuito Tanno³, Soshi Okazaki³, So Itoi³, Yosuke Hoshi³, Tomoaki Machiyama³, Yusho Ishii³, Hiroko Sato³ and Hiroshi Fujii³, ¹Department of Rheumatology, Tohoku University Hospital, Sendai, Japan, ²Department of Rheumatology, Tohoku University Hospital, Sendai, Miyagi, Japan, ³Department of Rheumatology, Tohoku University Hospital, Sendai

Background/Purpose: PET/CT enables assessment of active vascular inflammation in Takayasu arteritis (TAK), which is often difficult to evaluate with conventional imaging. Although the distribution of…
Abstract Number: 1204 • ACR Convergence 2025
Validity and reliability of a new ultrasound-based semiquantitative echogenicity grading scale for myositis.
Takeshi Yoshida¹, Didem Saygin² and Jemima Albayda³, ¹Johns Hopkins Hospital, Baltimore, MD, ²Rush University Medical Center, Chicago, IL, ³Johns Hopkins University, Baltimore, MD
Background/Purpose: The Heckmatt grading scale has been widely used as a semiquantitative assessment method for grading muscle echo intensity (EI) on ultrasound; however, this was…

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