Abstracts tagged "Imaging"

Abstract Number: 1646 • ACR Convergence 2023
The Real-World Experience of Combined Cranial and Large Vessel FDG-PET/CT in the Investigation of Giant Cell Arteritis
Keren Port¹, Ivan Ho Shon¹, Sally Ayesa¹, Rachel Langford¹, Olivia Bennett¹, Andrew Csillag¹, Stacey Fredericks¹, Luz Palacios-Derflingher², Eva Wegner¹ and Anthony Sammel¹, ¹The Prince of Wales Hospital, Sydney, Australia, ²University of New South Wales, Sydney, Australia
Background/Purpose: GCA is a systemic medium-large vessel vasculitis (M-LVV) involving the cranial arteries, aorta and its major branches. Recent studies have shown that PET/CT including…
Abstract Number: 1891 • ACR Convergence 2023
Effect of Apremilast on Disease Interception in Patients with Psoriasis at Increased Risk of Developing PsA – Results of the Prospective Interventional Epos Trial
David Simon¹, Ioanna Minopoulou¹, Sara Bayat¹, Koray Tascilar¹, Melek Yalcin Mutlu¹, Filippo Fagni¹, Georg Schett² and Arnd Kleyer³, ¹Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology / Deutsches Zentrum Immuntherapie, Erlangen, Germany, ²Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ³Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Entheseal bone changes occur in a substantial proportion of psoriasis patients [1] and are associated with an increased risk of developing psoriatic arthritis (PsA)…
Abstract Number: 2398 • ACR Convergence 2023
FDG Uptake in Limb Arteries at Diagnosis of Giant Cell Arteritis and Risk of Relapse: An Observational Cohort Study
Geoffroy Peyrac¹, Arthur Mageau², Augustin Gaudemer², Khadija Benali¹, Jean-Francois Alexandra¹, Andrey Strukov¹, Sebastien Ottaviani¹, Thomas Papo² and Karim Sacre², ¹Assistance Publique Hopitaux de Paris, Paris, France, ²Université Paris Cité, Paris, France
Background/Purpose: Steroids and anti-IL6 biotherapy are highly effective in obtaining remission in patients with giant cell arteritis (GCA) but the risk of relapses remains high,…
Abstract Number: 0749 • ACR Convergence 2023
Impact of Sprifermin on Denuded Areas of Subchondral Bone (dABs): A Post Hoc Analysis of the FORWARD Study
Felix Eckstein¹, Wolfgang Wirth², Philip Conaghan³, Marc Hochberg⁴, Ali Guermazi⁵, Jade Andrade⁶, Luping Zhao⁶ and Niti Goel⁷, ¹Paracelsus Medical University, Institute of Anatomy & Ludwig Boltzmann Institute, and Chondrometrics GmbH, Salzburg, Austria, ²Paracelsus Medical University, Institute of Anatomy & Ludwig Boltzmann Institute, and Chondrometrics GmbH, Freilassing, Germany, ³University of Leeds, Leeds, United Kingdom, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Boston University, Boston, MA, ⁶TrialSpark, New York, NY, ⁷TrialSpark, Duke University, Durham, NC
Background/Purpose: Sprifermin, recombinant human fibroblast growth factor 18 (rhFGF-18), is being investigated as a potential disease-modifying osteoarthritis drug. The Phase 2 FORWARD study demonstrated that…
Abstract Number: 1115 • ACR Convergence 2023
EULAR Recommendations for the Use of Imaging in the Diagnosis and Management of Crystal-induced Arthropathies in Clinical Practice
Peter Mandl¹, Maria-Antonietta D'Agostino², Victoria Navarro-Compán³, Irina Gessl¹, Garifallia Sakellariou⁴, Abhishek Abhishek⁵, Fabio Becce⁶, Nicola Dalbeth⁷, Hang-Korng Ea⁸, Emilio Filippucci⁹, Hilde Berner Hammer¹⁰, Annamaria Iagnocco¹¹, Annette De Thurah¹², Esperanza Naredo¹³, Sebastien Ottaviani¹⁴, Tristan Pascart¹⁵, Fernando Perez-Ruiz¹⁶, Irene Pitsillidou¹⁷, Fabian Proft¹⁸, Juergen Rech¹⁹, Wolfgang Schmidt²⁰, Luca Sconfienza²¹, Lene Terslev²², Brigitte Wildner²³, Pascal Zufferey²⁴ and Georgios Filippou²⁵, ¹Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Universita Cattolica del Sacro Cuore Rome, Courbevoie, France, ³Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ⁴Department of Internal Medicine and Therapeutics, Università di Pavia, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy, ⁵University of Nottingham, Nottingham, United Kingdom, ⁶Lausanne University Hospital (CHUV), Lausanne, Switzerland, ⁷University of Auckland, Auckland, New Zealand, ⁸Hôpital Lariboisière, APHP-Nord, Service de Rhumatologie, Université de Paris Cité, Paris, France, ⁹Polytechnic University of Marche, Jesi, Italy, ¹⁰Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway AND University of Oslo, Faculty of Medicine, Oslo, Norway, ¹¹University of Turin, Roma, Italy, ¹²Aarhus University Hospital, Aarhus, Denmark, ¹³Hospital Fundación, Madrid, Spain, ¹⁴Assistance Publique Hopitaux de Paris, Paris, France, ¹⁵Department of Rheumatology, Saint-Philibert Hospital, Lille Catholic University, Lille, France, ¹⁶Rheumatology Division, Osakidetza, OSI-EE Cruces, Cruces University Hospital, Barakaldo, Spain, ¹⁷EULAR Patient Research Partner, Executive Secretary of Cyprus League Against Rheumatism, Nicosia, Cyprus, ¹⁸Department of Gastroenterology, Infectiology and Rheumatology (including Nutrition Medicine), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ¹⁹University Clinic Erlangen, Erlangen, Germany, ²⁰Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany, ²¹Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano AND IRCCS Istituto Ortopedico Galeazzi, 20161, Milan, Italy, ²²Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ²³University Library, Medical University of Vienna, Vienna, Austria, ²⁴Rheumatology Department, University of Lausanne, CHUV, Lausenne, Switzerland, ²⁵IRCCS Galeazzi - Sant'Ambrogio Hospital, Milan, Italy
Background/Purpose: The multifaceted clinical presentation in crystal-induced arthropathies (CiA) poses challenges to imaging. Our goal was to formulate evidence-based recommendations on the use of imaging…
Abstract Number: 1647 • ACR Convergence 2023
Association Between Vascular FDG Uptake at Diagnosis and Evolution in Aortic Dimensions in Giant Cell Arteritis: A Prospective Study
Lien Moreel¹, Walter Coudyzer², Lennert Boeckxstaens³, Albrecht Betrains¹, Geert Molenberghs⁴, Steven Vanderschueren¹, Eveline Claus², Koen Van Laere⁵ and Daniel Blockmans¹, ¹Department of General Internal Medicine, University Hospitals Leuven, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium, ²Department of Radiology, University Hospitals Leuven, Leuven, Belgium, ³Department of Nuclear Medicine, University Hospitals Leuven, Leuven, Belgium, ⁴Interuniversity Institute for Biostatistics and Statistical Bioinformatics (I-BioStat), University of Leuven and Hasselt University, Leuven, Belgium, ⁵Department of Nuclear Medicine, University Hospitals Leuven,Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, KU Leuven, Leuven, Belgium
Background/Purpose: Patients with giant cell arteritis (GCA) have an increased risk of developing thoracic aortic aneurysms. Retrospective studies have shown that 18F-fluorodeoxyglucose (FDG) uptake in…
Abstract Number: 1892 • ACR Convergence 2023
Sacroiliac Bone Marrow Oedema on Postpartum MRI Does Not Result in Significant SpA-like Structural Lesions: Results of a 5-year Follow-up Study
De Meester Liesbet¹, Gaelle Varkas², Manouk de Hooge³, Ann-Sophie De Craemer⁴, Nele Herregods⁵, Lennart Jans⁵, Philippe Carron⁶, Dirk Elewaut⁷ and Filip Van den Bosch⁸, ¹Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ²Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium, ³Ghent University Hospital, Hesperange, Luxembourg, ⁴Ghent University Hospital, Gent, Belgium, ⁵Department of Radiology, Ghent University Hospital, Ghent, Belgium, ⁶UZ Gent, Gent, Belgium, ⁷Ghent University and VIB Center for Inflammation Research, Ghent, Belgium, ⁸Department of Internal Medicine and Pediatrics, Ghent University and VIB Center for Inflammation Research, Ghent, Belgium
Background/Purpose: Sacroiliac bone marrow oedema (BMO) on MRI, immediately after childbirth, has been observed in a large proportion of postpartum women and appears to be…
Abstract Number: 2403 • ACR Convergence 2023
Systole and Diastole Ultrasound Wall Thickness Shows Significant Differences That Affect the Diagnosis and Assessment of Giant Cell Arteritis
Emma Brugarolas¹, Elisa Fernandez-Fernandez², Irene Monjo³ and Eugenio De Miguel⁴, ¹Hospital Universitari de Bellvitge, Girona, Spain, ²La Paz University Hospital, Madrid, Spain, ³University Hospital La Paz, Madrid, Spain, ⁴Hospital Universitario La Paz, Madrid, Spain
Background/Purpose: In the last few years, several cut-off points for the intima-media thickness (IMT) of temporal arteries (TA) and large vessels (LV) have been proposed…
Abstract Number: 0750 • ACR Convergence 2023
Multispectral Optoacoustic Tomography of the Entheses Reveals Common Metabolic and Architectural Tissue Patterns in Psoriasis and Psoriatic Arthritis Independent of Inflammation
Filippo Fagni¹, Koray Tascilar¹, Rita Noversa de Sousa², Sara Bayat¹, Lukas Sollfrank³, Arnd Kleyer⁴, Michael Sticherling⁵, Adrian Regensburger⁶, Ferdinand Knieling⁶, Georg Schett⁷, Maximilian Waldner⁸ and David Simon¹, ¹Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology / Deutsches Zentrum Immuntherapie, Erlangen, Germany, ²Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, ³Department Dermatology, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, ⁴University Hospital Erlangen, Erlangen, Germany, ⁵Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Dermatology, Erlangen, Germany, ⁶Department of Pediatrics and Adolescent Medicine, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, ⁷Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ⁸Department of Internal Medicine 1, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Multispectral optoacoustic tomography (MSOT) is a novel imaging platform that combines ultrasound (US) with optoacoustic imaging to allow non-invasive in vivo quantification of key…
Abstract Number: 1193 • ACR Convergence 2023
The Association of Peak Forces and Loading Rates During Walking with MRI-Based Structural Worsening of the Knee: The Multicenter Osteoarthritis Study
Lauren Sara¹, David Felson¹, Michael LaValley², Gabriela Rabasa¹, Beth Lewis³, John Lynch⁴, Neil Segal⁵, Ali Guermazi¹, Frank Roemer⁶, Joshua Stefanik⁷ and Cara Lewis¹, ¹Boston University, Boston, MA, ²Boston University School of Public Health, Arlington, MA, ³University of Alabama at Birimingham, Birmingham, AL, ⁴University of California San Francisco, San Francisco, CA, ⁵University of Kansas, Kansas City, KS, ⁶Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany, ⁷Northeastern University, Boston, MA
Background/Purpose: Mechanical loading is an important, modifiable risk factor for knee osteoarthritis (OA). Walking loads have been previously proposed as a risk factor for developing…
Abstract Number: 1648 • ACR Convergence 2023
EULAR Recommendations for the Use of Imaging in Large Vessel Vasculitis in Clinical Practice: 2023 Update
Christian Dejaco¹, Sofia Ramiro², Milena Bond³, Philipp Bosch⁴, Cristina Ponte⁵, Sarah Mackie⁶, Thorsten Bley⁷, Daniel Blockmans⁸, Sara Brolin⁹, Ertugrul Cagri Bolek¹⁰, Rebecca Cassie¹¹, Maria C Cid¹², Juan Molina-Collada¹³, Bhaskar Dasgupta¹⁴, Berit Dalsgaard Nielsen¹⁵, Eugenio De Miguel¹⁶, Haner Direskeneli¹⁷, Christina Duftner¹⁸, Alojzija Hocevar¹⁹, Anna Molto²⁰, Valentin Sebastian Schäfer²¹, Luca Seitz²², Riemer H.J.A. Slart²³ and Wolfgang Schmidt²⁴, ¹Azienda Sanitaria Alto Adige, Brunico, Italy, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Azienda sanitaria dell'Alto Adige, Merano, Italy, ⁴Medical University of Graz, Graz, Austria, ⁵Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, ⁶Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁷Institute of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, ⁸Department of General Internal Medicine, University Hospitals Leuven, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium, ⁹Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden, ¹⁰1-Hacettepe University Vasculitis Research Centre, Ankara, Turkey/ 2-Vasculitis Translational Research Program, NIAMS, NIH, US, Ankara, Turkey, ¹¹n/a, Leicester, United Kingdom, ¹²Hospital Clinic Barcelona, Barcelona, Spain, ¹³Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹⁴Mid & South Essex University Hospitals NHS Foundation Trust; Southend University Hospital, Westcliff-on-sea, United Kingdom, ¹⁵Department of Internal Medicine, Horsens, Denmark, ¹⁶Hospital Universitario La Paz, Madrid, Spain, ¹⁷Division of Rheumatology, Medical School, Marmara University, Istanbul, Turkey, ¹⁸Medical University Innsbruck, Innsbruck, Austria, ¹⁹Department of Rheumatology, Universitiy Medical Centre Ljubljana, Ljubljana, Slovenia, ²⁰HOPITAL COCHIN AP-HP, Service de Rhumatologie, Paris, France, ²¹Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, ²²Rheumatology and Immunology, Inselspital University Hospital Bern, Bern, Switzerland, ²³University of Twente, Enschede, Netherlands, ²⁴Rheumatology, Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany
Background/Purpose: Imaging recommendations for primary large vessel vasculitis (LVV) were developed in 2018. Several new studies have emerged since then, and an update of the…
Abstract Number: 1893 • ACR Convergence 2023
Abnormalities Detected with [18F]-FDG-PET/CT Imaging in VEXAS Syndrome
Albrecht Betrains¹, Vincent Jachiet², Yannick Dieudonne³, Jérémie Dion⁴, Estibaliz Lazaro⁵, Claire De Moreuil⁶, Samuel Ardois⁷, Sylvie Grosleron⁸, Jean-benoit Arlet⁹, Cécile-Audrey Durel¹⁰, Laure Delaval¹¹, Sylvain Audia¹², Cécile Golden¹³, Barbara Nicolas¹³, Vincent Langlois¹⁴, Antoinette Perlat⁷, Frédéric Vandergheynst¹⁵, Thomas Moulinet¹⁶, Maxime Samson¹⁷, Daniel Blockmans¹, Olivier Kosmider¹⁸, Sophie Georgin-Lavialle¹⁹, Arsène Mekinian²⁰ and Benjamin Terrier²¹, ¹Department of General Internal Medicine, University Hospitals Leuven, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium, ²Service de médecine interne et Inflammation-Immunopathology-Biotherapy Department (DMU i3), Sorbonne Université, AP-HP, Hôpital Saint Antoine, Paris, France, ³Department of Clinical Immunology and Internal Medicine, National Reference Centre for Systemic Autoimmune Diseases (CNR RESO), Strasbourg University Hospital, Strasbourg, France, ⁴Internal Medicine Department, Toulouse University Hospital, Toulouse, France, ⁵Bordeaux Hospital University, Pessac, France, ⁶CHU de Brest, Brest, France, ⁷CHU Rennes, Rennes, France, ⁸CH Agen-Nérac, Agen, France, ⁹Hôpital Georges-Pompidou APHP, Paris, France, ¹⁰CHU Lyon, Lyon, France, ¹¹Hôpital Bichat APHP, Paris, France, ¹²Department of Internal Medicine and Clinical Immunology, Dijon-Bourgogne University Hospital, Dijon, France, ¹³CHU Dijon, Dijon, France, ¹⁴Service de Médecine Interne, Hôpital Jacques Monod, Le Havre, France, ¹⁵Université Libre de Bruxelles, Bruxelles, Belgium, ¹⁶Department of Internal Medicine, Centre hospitalier universitaire de Nancy, Nancy, France, ¹⁷Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, ¹⁸Hôpital Cochin APHP, Paris, France, ¹⁹AP-HP, Tenon hospital, Paris, France, ²⁰Department of Internal Medicine, Hôpital Saint-Antoine, AP-HP, Paris, France, ²¹Department of Internal Medicine, Hôpital Cochin, AP-HP, Paris, France
Background/Purpose: VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is anautoinflammatory syndrome caused by somatic mosaicism in the UBA1 gene. [18F]-FDG-PET/CT is often performed during…
Abstract Number: 2411 • ACR Convergence 2023
C-X-C Motif Chemokine Receptor 4-targeted Molecular Imaging in Giant Cell Arteritis – a Head-to-head Comparison with FDG PET
Matthias Froehlich¹, Sebastian E. Serfling², Michael Gernert³, Konstanze V. Guggenberger⁴, Takahiro Higuchi², Samuel Samnick², Marc Schmalzing⁵, Andreas K. Buck², Thorsten Bley⁴ and Rudolf A. Werner², ¹Rheumatology/Clinical Immunology, Department of Internal Medicine II, University of Würzburg, Würzburg, Germany, ²Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany, ³Medical Department II, Rheumatology, University Hospital Würzburg, Würzburg, Germany, ⁴Institute of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, ⁵University Hospital, Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany
Background/Purpose: 2-[18F]fluoro-2-deoxy-D-glucose(FDG) is the reference PET radiotracer for detecting inflammation in giant cell arteritis (GCA). C-X-C motif chemokine receptor 4 (CXCR4)-directed PET, however, allows for…
Abstract Number: 0812 • ACR Convergence 2023
Length of Synovial Fluid Monosodium Urate Crystals According to Sonographic Articular Deposits: Advancing in the Crystallization Process
Elena Sansano¹, Mª Carmen López-González², Cristina Rodríguez-Alvear³, Irene Calabuig-Sais³, Agustín Martínez-Sanchís³, Eliseo Pascual³ and Mariano Andrés³, ¹Miguel Hernandez University, Alicante, Spain, ²General University Hospital Dr. Balmis, Alacante, Spain, ³Dr Balmis Alicante General University Hospital-ISABIAL, Alicante, Spain
Background/Purpose: We described bands of fibers having deposited orderly arrayed monosodium urate (MSU) crystals suggesting the need for protein templates to start crystallization [PMID 9709185].…
Abstract Number: 1194 • ACR Convergence 2023
Extent of Subregional Involvement of Subchondral Bone Marrow Lesions in Incident Knee OA Is Associated with Weight-Bearing Knee Pain
Kent Kwoh¹, Frank Roemer², Erin Ashbeck³ and Ali Guermazi⁴, ¹University of Arizona, Tucson, AZ, ²Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany, ³University of Arizona Arthritis Center, Tucson, AZ, ⁴Boston University, Boston, MA
Background/Purpose: Subchondral bone marrow lesions (BMLs) have been associated with incident and progressive pain and reported to fluctuate along with concurrent fluctuations in symptoms. While…

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