Abstracts tagged "imaging techniques"

Abstract Number: 046 • 2020 Pediatric Rheumatology Symposium
Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare
Richard Bell ¹, Homaira Rahimi², H. Mark Kenney ², Ronald Wood ², Alicia Lieberman ³, Edward Schwarz ⁴ and Christopher Ritchlin ⁵, ¹University of Rochester Medical Center, Rochester, ²University of Rochester, Rochester, ³Batavia, ⁴University of Rochester, Rochester, NY, USA, Rochester, ⁵University of Rochester Medical Center, Canandaigua
Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis have established abnormal lymphatic vessel (LV) function during…
Abstract Number: 715 • 2019 ACR/ARP Annual Meeting
Imaging Technique (R)evolution to Measure the Digital Microcirculatory Flow in Systemic Sclerosis: A Systematic Review
Karin Melsens¹, Amber Vanhaecke ¹, Wies Van Eenoo ², Maurizio Cutolo ³ and Vanessa Smith ⁴, ¹Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ²Faculty of Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ³Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genoa, Italy, ⁴Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium, Gent, Belgium
Background/Purpose: Systemic sclerosis (SSc) is a chronic, auto-immune disease characterised by a widespread vasculopathy. There is a high need to obtain validated outcome measures for…
Abstract Number: 901 • 2019 ACR/ARP Annual Meeting
Sensitivity of Dual-Energy CT, Ultrasound, and X-Ray for Pseudogout: A Pilot Study
Sara K. Tedeschi¹, Daniel Solomon ², Kathleen Vanni ³, Dong Suh ³ and Stacy Smith ⁴, ¹Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ²Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston
Background/Purpose: Advanced imaging modalities such as ultrasound (US) and dual-energy CT (DECT) can help diagnose crystalline arthritis. DECT is a highly sensitive and specific modality…
Abstract Number: 1972 • 2019 ACR/ARP Annual Meeting
Identification of Distinct Lipidomic Profiles in Synovial Membranes from Inflammatory Arthritis by Mass Spectrometry Imaging
Beatriz Rocha¹, Berta Cillero-Pastor ², Cristina Ruiz-Romero ³, Andrea Cuervo ⁴, Ron M A Heeren ², Juan Cañete ⁵ and Francisco J. Blanco ⁶, ¹Proteomics Group-ProteoRed/ISCIII, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain, A Coruña, Galicia, Spain, ²The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, The Netherlands., Maastricht, Limburg, Netherlands, ³Proteomics Group-ProteoRed/ISCIII, CIBER-BBN, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain., A Coruña, Spain, ⁴Arthritis Unit, Rheumatology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain., Barcelona, Catalonia, Spain, ⁵Rheumatology Department, Hospital Clínic and IDIBAPS,, Barcelona, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain
Background/Purpose: Early diagnosis of inflammatory arthritis is associated with improved patient outcomes. However, accurate diagnosis can be challenging because of their complexity and heterogeneous nature.…
Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting
Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis
Kaitlin Quinn¹, Joel S. Rosenblum ², Casey A. Rimland ³, K Bates Gribbons ⁴, Mark A. Ahlman ⁵ and Peter C. Grayson ⁶, ¹Georgetown University Hospital/National Institutes of Health, Washington, DC, ²National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ³National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV). Conventionally PET…
Abstract Number: 1075 • 2018 ACR/ARHP Annual Meeting
Automated Multiparameter Microscopy and Image Analysis: Next Generation Synovial Tissue Histology
William Murray-Brown¹, Helen Weedon¹, Amanda Aloia², Susan Lester³, Susanna Proudman⁴, Malcolm D. Smith⁵, Jenny Walker¹ and Mihir D Wechalekar^1,3, ¹Rheumatology, Flinders University, Adelaide, Australia, ²Cellular Imaging, Flinders University, Adelaide, Australia, ³Royal Adelaide Hospital, Adelaide, Australia, ⁴Royal Adelaide Hospital, Rheumatology Unit and University of Adelaide, Discipline of Medicine, Adelaide, Australia, ⁵Rheumotology, Flinders University, Adelaide, Australia
Background/Purpose: Currently, histological assessment of synovial tissue (ST) in Rheumatoid Arthritis (RA) is hampered by 3 main factors: 1) tissue is a finite resource, 2)…
Abstract Number: 1337 • 2018 ACR/ARHP Annual Meeting
Myocardial Fatty Acid Metabolism and Perfusion Mismatch in Scintigraphy Predicts Worse Prognosis in Clinically Amyopathic Dermatomyositis
Harunobu Iida¹, Hironari Hanaoka¹, Kana Ishimori², Tomofumi Kiyokawa¹, Yukiko Takakuwa¹ and Kimito Kawahata¹, ¹Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ²Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Clinically amyopathic dermatomyositis (CADM) patients are frequently manifested by rapidly progressive interstitial lung disease (ILD) and associated with a poor prognosis. Recently cardiac involvement…
Abstract Number: 2207 • 2018 ACR/ARHP Annual Meeting
Detecting Hand Joint Ankylosis in Radiographic Images Using Deep Learning: A Step in Development of Automatic Radiographic Scoring System for Bone Destruction
Keisuke Izumi^1,2, Masahiro Hashimoto³, Kanata Suzuki⁴, Toshio Endoh⁴, Kentaro Doi⁵, Yuki Iwai⁵, Masahiro Jinzaki³, Shigeru Ko⁶ and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ³Department of Radiology, Keio University School of Medicine, Tokyo, Japan, ⁴Machine Learning Technology Project, Artificial Intelligence Laboratory, FUJITSU LABORATORIES LTD., Kawasaki, Japan, ⁵SOLUTIONS DEVELOPMENT DEPT.I, MEDICAL SOLUTIONS DIV.V, Healthcare Solutions Unit. II, FUJITSU LTD., Tokyo, Japan, ⁶Department of Systems Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Artificial intelligence (AI) techniques including deep learning have been rapidly evolving and shown good performance in many fields over recent years. However, there are…
Abstract Number: 2208 • 2018 ACR/ARHP Annual Meeting
Novel Fluorescence Optical Imaging Scoring System of Inflammation in the Hand and Wrist Is in Patients with Rheumatoid Arthritis – Agreement with Ultrasonography and Sensitivity to Change
Mads Ammitzbøll-Danielsen¹, Daniel Glinatsi¹, Lene Terslev² and Mikkel Østergaard^3,4, ¹Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Fluorescence optical imaging (FOI) has been used for assessment of inflammation in the hands and has in several cross sectional studies been compared with…
Abstract Number: 2321 • 2018 ACR/ARHP Annual Meeting
Dickkopf-1 Serum Levels in Patients with Systemic Sclerosis and Correlation with Trabecular Bone Score
Barbara Ruaro¹, Andrea Casabella², Sabrina Paolino¹, Carmen Pizzorni², Vanessa Smith³, Chiara Seriolo⁴, Luigi Molfetta⁴, Patrizio Odetti⁴ and Maurizio Cutolo², ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Centro di Ricerca su Osteoporosi e Patologie Osteoarticolari CROPO, Di.M.I., Genoa, Italy, Genoa, Italy
Background/Purpose: Dickkopf-1 (DKK1) is a natural inhibitor of Wnt signaling pathway that could be involved in promoting osteoclastogenesis through suppression of osteoprotegerin (1,2). Systemic sclerosis…
Abstract Number: 1287 • 2017 ACR/ARHP Annual Meeting
Cone Beam Computed Tomography for the Assessment of Linear Scleroderma of the Face
Francesco Zulian¹, Chiara Di Giovanni², Stafano Puggina³, Alessandra Meneghel¹, Sabina Trainito⁴ and Giorgia Martini², ¹University of Padua, Department of Woman and Child Health, Padua, Italy, ²Department of Woman and Child Health, University of Padua, Padua, Italy, ³Unix Radiology Service, Affidea Group inc., Piove di Sacco, Italy, ⁴Division of Physical Medicine and Rehabilitation, University of Padua, Padua, Italy
Background/Purpose: Linear scleroderma of the face (LSF) is a very disabling condition and, to date, standardized and validated methods for assessing and monitoring the disease…
Abstract Number: 2007 • 2017 ACR/ARHP Annual Meeting
Disturbances of the Acral Perfusion Detected By Fluorescence Optical Imaging Are Associated with the Development of Ischemic Complications in Patients with Systemic Sclerosis
Stefanie Friedrich^1,2, Susanne Lueders³, Stephanie Werner^3,4, Anne-Marie Glimm⁵, Gabriela Schmittat⁵, Gerd R. Burmester⁶, Gabriela Riemekasten⁷, Marina Backhaus⁸ and Sarah Ohrndorf⁹, ¹Department of of Rheumatology and Clinical Immunology, Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin; Germany, Berlin, Germany, ²Department of Radiology, Department of Radiology, Charité University Hospital, Berlin; Germany, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin; Germany, Berlin, Germany, ⁴Department of Rheumatology, Helios St. Johannes Clinic, Duisburg, Germany, ⁵Department of Rheumatology and Clinical Immunology, Charité University Medicine Berlin, Berlin, Germany, ⁶Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, ⁷Department of Rheumatology, Universitatsklinikum Schleswig-Holstein, Lubeck, Germany, ⁸Rheumatology, Park-Klinik Weissensee, Berlin, Germany, ⁹Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany
Background/Purpose: Systemic sclerosis (SSc) is a condition causing impaired microcirculation with the risk of ischemic complications such as digital ulcers and pitting scars (DU/PS). Fluorescence…
Abstract Number: 2025 • 2017 ACR/ARHP Annual Meeting
Potential Clinical Utility of Manu-Scan, the Novel Optical Molecular Imaging, in Patients with Hand Rheumatoid Arthritis
Dong Jin Go¹, Sang Jin Lee^1,2, Sang Hyun Joo³, Eun Hye Park⁴, Gi Jeong Cheon⁵, Sung Hwan Hong⁶ and Yeong Wook Song^1,4, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Seoul National University, Seoul, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Hospital, Seoul, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, Jungang Medical Foundation, Jeju, Korea, Republic of (South), ⁴Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ⁵Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South), ⁶Department of Radiology, Seoul National University Hospital, Seoul, Korea, Republic of (South)
Background/Purpose: Recently, optical molecular imaging is expected to serve as the new technique for early diagnosis and treatment monitoring of rheumatoid arthritis (RA). "Manu-Scan" is…
Abstract Number: 2889 • 2017 ACR/ARHP Annual Meeting
Aminaphtone Ameliorates Clinical Symptoms and Increases Skin Blood Perfusion in Patients with Both Primary and Secondary Raynaud Phenomenon: A Six-Month Open Study
Alberto Sulli¹, Maurizio Cutolo², Carmen Pizzorni², Sabrina Paolino², Elisa Alessandri², Emanuele Gotelli² and Barbara Ruaro², ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genova, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genoa, Italy
Background/Purpose: Current treatments for Raynaud's phenomenon (RP) have limited efficacy, which was mainly demonstrated by physician/patient reported outcomes. Aminaphtone is a vasoactive drug recently suggested…
Abstract Number: 2973 • 2017 ACR/ARHP Annual Meeting
Detection of Clinical Signs of Arthritis and Subclinical Evidence of Inflammation in Psoriasis Patients with Risk for Arthritis: Value of Clinical Examination, Ultrasound and Fluorescence-Optical Imaging – Results from the Prospective Multicentre Xciting Study
Michaela Koehm¹, Tanja Rossmanith², Hans-Eckhard Langer³, Marina Backhaus⁴, Gerd R. Burmester⁵, Siegfried Wassenberg⁶, Benjamin Köhler⁶, Harald Burkhardt⁷ and Frank Behrens⁸, ¹Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt/Main, Germany, ²Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Frankfurt, Germany, ³RHIO (Rheumatology, Immunology, Osteology) Duesseldorf, Duesseldorf, Germany, ⁴Rheumatology, Park-Klinik Weissensee, Berlin, Germany, ⁵Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, ⁶Rheumazentrum Ratingen, Ratingen, Germany, ⁷Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt, Germany, ⁸Clinical Research Rheumatology and Fraunhofer Institute IMETranslation, Goethe University, Frankfurt, Germany
Background/Purpose: Psoriasis (Pso) is one of the most common chronic inflammatory skin diseases in Europe. Psoriatic arthritis (PsA) is closely associated to Pso whereas the…

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