ACR Meeting Abstracts

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Abstracts tagged "imaging techniques"

  • Abstract Number: 046 • 2020 Pediatric Rheumatology Symposium

    Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare

    Richard Bell 1, Homaira Rahimi2, H. Mark Kenney 2, Ronald Wood 2, Alicia Lieberman 3, Edward Schwarz 4 and Christopher Ritchlin 5, 1University of Rochester Medical Center, Rochester, 2University of Rochester, Rochester, 3Batavia, 4University of Rochester, Rochester, NY, USA, Rochester, 5University of Rochester Medical Center, Canandaigua

    Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis have established abnormal lymphatic vessel (LV) function during…
  • Abstract Number: 1972 • 2019 ACR/ARP Annual Meeting

    Identification of Distinct Lipidomic Profiles in Synovial Membranes from Inflammatory Arthritis by Mass Spectrometry Imaging

    Beatriz Rocha1, Berta Cillero-Pastor 2, Cristina Ruiz-Romero 3, Andrea Cuervo 4, Ron M A Heeren 2, Juan Cañete 5 and Francisco J. Blanco 6, 1Proteomics Group-ProteoRed/ISCIII, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain, A Coruña, Galicia, Spain, 2The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, The Netherlands., Maastricht, Limburg, Netherlands, 3Proteomics Group-ProteoRed/ISCIII, CIBER-BBN, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain., A Coruña, Spain, 4Arthritis Unit, Rheumatology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain., Barcelona, Catalonia, Spain, 5Rheumatology Department, Hospital Clínic and IDIBAPS,, Barcelona, Spain, 6Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain

    Background/Purpose: Early diagnosis of inflammatory arthritis is associated with improved patient outcomes. However, accurate diagnosis can be challenging because of their complexity and heterogeneous nature.…
  • Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting

    Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis

    Kaitlin Quinn1, Joel S. Rosenblum 2, Casey A. Rimland 3, K Bates Gribbons 4, Mark A. Ahlman 5 and Peter C. Grayson 6, 1Georgetown University Hospital/National Institutes of Health, Washington, DC, 2National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, 3National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, 4National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 5Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, 6National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD

    Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV).  Conventionally PET…
  • Abstract Number: 715 • 2019 ACR/ARP Annual Meeting

    Imaging Technique (R)evolution to Measure the Digital Microcirculatory Flow in Systemic Sclerosis: A Systematic Review

    Karin Melsens1, Amber Vanhaecke 1, Wies Van Eenoo 2, Maurizio Cutolo 3 and Vanessa Smith 4, 1Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, 2Faculty of Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, 3Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genoa, Italy, 4Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium, Gent, Belgium

    Background/Purpose: Systemic sclerosis (SSc) is a chronic, auto-immune disease characterised by a widespread vasculopathy. There is a high need to obtain validated outcome measures for…
  • Abstract Number: 901 • 2019 ACR/ARP Annual Meeting

    Sensitivity of Dual-Energy CT, Ultrasound, and X-Ray for Pseudogout: A Pilot Study

    Sara K. Tedeschi1, Daniel Solomon 2, Kathleen Vanni 3, Dong Suh 3 and Stacy Smith 4, 1Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, 2Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Brigham and Women's Hospital, Boston

    Background/Purpose: Advanced imaging modalities such as ultrasound (US) and dual-energy CT (DECT) can help diagnose crystalline arthritis. DECT is a highly sensitive and specific modality…
  • Abstract Number: 1075 • 2018 ACR/ARHP Annual Meeting

    Automated Multiparameter Microscopy and Image Analysis: Next Generation Synovial Tissue Histology

    William Murray-Brown1, Helen Weedon1, Amanda Aloia2, Susan Lester3, Susanna Proudman4, Malcolm D. Smith5, Jenny Walker1 and Mihir D Wechalekar1,3, 1Rheumatology, Flinders University, Adelaide, Australia, 2Cellular Imaging, Flinders University, Adelaide, Australia, 3Royal Adelaide Hospital, Adelaide, Australia, 4Royal Adelaide Hospital, Rheumatology Unit and University of Adelaide, Discipline of Medicine, Adelaide, Australia, 5Rheumotology, Flinders University, Adelaide, Australia

    Background/Purpose: Currently, histological assessment of synovial tissue (ST) in Rheumatoid Arthritis (RA) is hampered by 3 main factors: 1) tissue is a finite resource, 2)…
  • Abstract Number: 1337 • 2018 ACR/ARHP Annual Meeting

    Myocardial Fatty Acid Metabolism and Perfusion Mismatch in Scintigraphy Predicts Worse Prognosis in Clinically Amyopathic Dermatomyositis

    Harunobu Iida1, Hironari Hanaoka1, Kana Ishimori2, Tomofumi Kiyokawa1, Yukiko Takakuwa1 and Kimito Kawahata1, 1Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, 2Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Clinically amyopathic dermatomyositis (CADM) patients are frequently manifested by rapidly progressive interstitial lung disease (ILD) and associated with a poor prognosis. Recently cardiac involvement…
  • Abstract Number: 2207 • 2018 ACR/ARHP Annual Meeting

    Detecting Hand Joint Ankylosis in Radiographic Images Using Deep Learning: A Step in Development of Automatic Radiographic Scoring System for Bone Destruction

    Keisuke Izumi1,2, Masahiro Hashimoto3, Kanata Suzuki4, Toshio Endoh4, Kentaro Doi5, Yuki Iwai5, Masahiro Jinzaki3, Shigeru Ko6 and Tsutomu Takeuchi1, 1Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 2Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, 3Department of Radiology, Keio University School of Medicine, Tokyo, Japan, 4Machine Learning Technology Project, Artificial Intelligence Laboratory, FUJITSU LABORATORIES LTD., Kawasaki, Japan, 5SOLUTIONS DEVELOPMENT DEPT.I, MEDICAL SOLUTIONS DIV.V, Healthcare Solutions Unit. II, FUJITSU LTD., Tokyo, Japan, 6Department of Systems Medicine, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose:  Artificial intelligence (AI) techniques including deep learning have been rapidly evolving and shown good performance in many fields over recent years. However, there are…
  • Abstract Number: 2208 • 2018 ACR/ARHP Annual Meeting

    Novel Fluorescence Optical Imaging Scoring System of Inflammation in the Hand and Wrist Is in Patients with Rheumatoid Arthritis – Agreement with Ultrasonography and Sensitivity to Change

    Mads Ammitzbøll-Danielsen1, Daniel Glinatsi1, Lene Terslev2 and Mikkel Østergaard3,4, 1Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 2Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, 3Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 4Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Fluorescence optical imaging (FOI) has been used for assessment of inflammation in the hands and has in several cross sectional studies been compared with…
  • Abstract Number: 2321 • 2018 ACR/ARHP Annual Meeting

    Dickkopf-1 Serum Levels in Patients with Systemic Sclerosis and Correlation with Trabecular Bone Score

    Barbara Ruaro1, Andrea Casabella2, Sabrina Paolino1, Carmen Pizzorni2, Vanessa Smith3, Chiara Seriolo4, Luigi Molfetta4, Patrizio Odetti4 and Maurizio Cutolo2, 1Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, 2Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, 3Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 4Centro di Ricerca su Osteoporosi e Patologie Osteoarticolari CROPO, Di.M.I., Genoa, Italy, Genoa, Italy

    Background/Purpose: Dickkopf-1 (DKK1) is a natural inhibitor of Wnt signaling pathway that could be involved in promoting osteoclastogenesis through suppression of osteoprotegerin (1,2). Systemic sclerosis…
  • Abstract Number: 248 • 2017 ACR/ARHP Annual Meeting

    Validation of Objective Quantification System for Disease Progression in Patients with Juvenile Idiopathic Arthritis

    Olga Kubassova1, N Tzaribachev2, Romiesa Hagoug3 and Mikael Boesen4, 1R&D, Image Analysis Group, London, England, 2University Medical Center Schleswig-Holstein, Bad Bramstedt, Germany, 3Imaging, Image Analysis Group, London, United Kingdom, 4Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiskberg, Denmark

    Background/Purpose: Imaging as outcome measure has been studied and extensively used in the assessment of treatment for adult patients with rheumatoid arthritis (RA)1. In children…
  • Abstract Number: 256 • 2017 ACR/ARHP Annual Meeting

    Tracking Digital Ulcers in Systemic Sclerosis: Feasibility Study Assessing Lesion Area from Patient-Recorded Smartphone Photographs

    Graham Dinsdale1, Tonia Moore2, Joanne Manning2, Andrea Murray1, Ross Atkinson3, Karen Ousey4, Mark Dickinson5, Christopher Taylor6 and Ariane L. Herrick1,7, 1Division of Musculoskeletal & Dermatological Sciences, University of Manchester, Salford Royal Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom, 2Salford Royal Hospital NHS Foundation Trust, Salford, UK, Salford, United Kingdom, 3School of Health Sciences, Division of Nursing, Midwifery & Social Work, University of Manchester, Manchester, UK, Manchester, United Kingdom, 4Division of Podiatry and Clinical Sciences, University of Huddersfield, Huddersfield, UK, Huddersfield, United Kingdom, 5Photon Science Institute, School of Physics and Astronomy, University of Manchester, Manchester, UK, Manchester, United Kingdom, 6Centre for Imaging Sciences, Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK, Manchester, United Kingdom, 7NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom

    Background/Purpose: Approximately 50% of patients with systemic sclerosis (SSc) will develop painful digital (finger) ulcers (DUs) at some point during their disease course. These lesions…
  • Abstract Number: 592 • 2017 ACR/ARHP Annual Meeting

    Which Imaging Outcomes for AxSpA Are Most Sensitive to Change? a 5-Year Analysis of the DESIR Cohort

    Alexandre Sepriano1, Sofia Ramiro2, Désirée van der Heijde1, Maxime Dougados3, Pascal Claudepierre4, Antoine Feydy5, M. Reijnierse6, Damien Loeuille7 and Robert B.M. Landewé8, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, 3Paris-Descartes University,, Paris, France, 4Hôpital Henri Mondor, Créteil, France, 5Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, 6Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 8University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands

    Background/Purpose: Several imaging outcomes have become available to assess inflammation and structural damage over time in patients with axial spondyloarthris (axSpA). However, no formal comparison…
  • Abstract Number: 791 • 2017 ACR/ARHP Annual Meeting

    Aortic Dilatation in Patients with Large Vessel Vasculitis: A Longitudinal Case Control Study Using Positron Emission Tomography/Computed Tomography

    Filippo Crescentini1, Francesco Muratore2, Lucia Spaggiari3, Giulia Pazzola1, Luigi Boiardi1, Nicolò Pipitone1 and Carlo Salvarani4, 1Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio Emilia, Italy, 3Radiology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 4Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy

    Background/Purpose: To evaluate aortic diameter and predictors of aortic dilatation using FDG-PET/CT in a longitudinally followed cohort of patients with large vessel vasculitis (LVV) compared…
  • Abstract Number: 1287 • 2017 ACR/ARHP Annual Meeting

    Cone Beam Computed Tomography for the Assessment of Linear Scleroderma of the Face

    Francesco Zulian1, Chiara Di Giovanni2, Stafano Puggina3, Alessandra Meneghel1, Sabina Trainito4 and Giorgia Martini2, 1University of Padua, Department of Woman and Child Health, Padua, Italy, 2Department of Woman and Child Health, University of Padua, Padua, Italy, 3Unix Radiology Service, Affidea Group inc., Piove di Sacco, Italy, 4Division of Physical Medicine and Rehabilitation, University of Padua, Padua, Italy

    Background/Purpose: Linear scleroderma of the face (LSF) is a very disabling condition and, to date, standardized and validated methods for assessing and monitoring the disease…
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