Abstracts tagged "imaging techniques"

Abstract Number: 046 • 2020 Pediatric Rheumatology Symposium
Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare
Richard Bell ¹, Homaira Rahimi², H. Mark Kenney ², Ronald Wood ², Alicia Lieberman ³, Edward Schwarz ⁴ and Christopher Ritchlin ⁵, ¹University of Rochester Medical Center, Rochester, ²University of Rochester, Rochester, ³Batavia, ⁴University of Rochester, Rochester, NY, USA, Rochester, ⁵University of Rochester Medical Center, Canandaigua
Background/Purpose: Near infrared (NIR) imaging studies of subdermal indocyanine green (ICG) in murine models of inflammatory arthritis have established abnormal lymphatic vessel (LV) function during…
Abstract Number: 715 • 2019 ACR/ARP Annual Meeting
Imaging Technique (R)evolution to Measure the Digital Microcirculatory Flow in Systemic Sclerosis: A Systematic Review
Karin Melsens¹, Amber Vanhaecke ¹, Wies Van Eenoo ², Maurizio Cutolo ³ and Vanessa Smith ⁴, ¹Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ²Faculty of Medicine, Ghent University, Ghent, Belgium, Ghent, Belgium, ³Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genoa, Italy, ⁴Dept. of Rheumatology, Ghent University Hospital, Ghent, Belgium; Dept. of Internal Medicine, Ghent University, Ghent, Belgium; Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Ghent, Belgium, Gent, Belgium
Background/Purpose: Systemic sclerosis (SSc) is a chronic, auto-immune disease characterised by a widespread vasculopathy. There is a high need to obtain validated outcome measures for…
Abstract Number: 901 • 2019 ACR/ARP Annual Meeting
Sensitivity of Dual-Energy CT, Ultrasound, and X-Ray for Pseudogout: A Pilot Study
Sara K. Tedeschi¹, Daniel Solomon ², Kathleen Vanni ³, Dong Suh ³ and Stacy Smith ⁴, ¹Brigham and Women's Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ²Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston
Background/Purpose: Advanced imaging modalities such as ultrasound (US) and dual-energy CT (DECT) can help diagnose crystalline arthritis. DECT is a highly sensitive and specific modality…
Abstract Number: 1972 • 2019 ACR/ARP Annual Meeting
Identification of Distinct Lipidomic Profiles in Synovial Membranes from Inflammatory Arthritis by Mass Spectrometry Imaging
Beatriz Rocha¹, Berta Cillero-Pastor ², Cristina Ruiz-Romero ³, Andrea Cuervo ⁴, Ron M A Heeren ², Juan Cañete ⁵ and Francisco J. Blanco ⁶, ¹Proteomics Group-ProteoRed/ISCIII, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain, A Coruña, Galicia, Spain, ²The Maastricht Multimodal Molecular Imaging Institute (M4I), Division of Imaging Mass Spectrometry, Maastricht University, The Netherlands., Maastricht, Limburg, Netherlands, ³Proteomics Group-ProteoRed/ISCIII, CIBER-BBN, Grupo de Investigación de Reumatología (GIR), INIBIC – Hospital Universitario de A Coruña, A Coruña, Spain., A Coruña, Spain, ⁴Arthritis Unit, Rheumatology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain., Barcelona, Catalonia, Spain, ⁵Rheumatology Department, Hospital Clínic and IDIBAPS,, Barcelona, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain
Background/Purpose: Early diagnosis of inflammatory arthritis is associated with improved patient outcomes. However, accurate diagnosis can be challenging because of their complexity and heterogeneous nature.…
Abstract Number: 2922 • 2019 ACR/ARP Annual Meeting
Imaging Acquisition Technique Influences Interpretation of Positron Emission Tomography Vascular Activity in Large-Vessel Vasculitis
Kaitlin Quinn¹, Joel S. Rosenblum ², Casey A. Rimland ³, K Bates Gribbons ⁴, Mark A. Ahlman ⁵ and Peter C. Grayson ⁶, ¹Georgetown University Hospital/National Institutes of Health, Washington, DC, ²National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ³National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁵Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: 18F-flurodeoxyglucose (FDG) positron emission tomography (PET) is one of several imaging modalities used in the assessment of patients with large-vessel vasculitis (LVV). Conventionally PET…
Abstract Number: 1075 • 2018 ACR/ARHP Annual Meeting
Automated Multiparameter Microscopy and Image Analysis: Next Generation Synovial Tissue Histology
William Murray-Brown¹, Helen Weedon¹, Amanda Aloia², Susan Lester³, Susanna Proudman⁴, Malcolm D. Smith⁵, Jenny Walker¹ and Mihir D Wechalekar^1,3, ¹Rheumatology, Flinders University, Adelaide, Australia, ²Cellular Imaging, Flinders University, Adelaide, Australia, ³Royal Adelaide Hospital, Adelaide, Australia, ⁴Royal Adelaide Hospital, Rheumatology Unit and University of Adelaide, Discipline of Medicine, Adelaide, Australia, ⁵Rheumotology, Flinders University, Adelaide, Australia
Background/Purpose: Currently, histological assessment of synovial tissue (ST) in Rheumatoid Arthritis (RA) is hampered by 3 main factors: 1) tissue is a finite resource, 2)…
Abstract Number: 1337 • 2018 ACR/ARHP Annual Meeting
Myocardial Fatty Acid Metabolism and Perfusion Mismatch in Scintigraphy Predicts Worse Prognosis in Clinically Amyopathic Dermatomyositis
Harunobu Iida¹, Hironari Hanaoka¹, Kana Ishimori², Tomofumi Kiyokawa¹, Yukiko Takakuwa¹ and Kimito Kawahata¹, ¹Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ²Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Clinically amyopathic dermatomyositis (CADM) patients are frequently manifested by rapidly progressive interstitial lung disease (ILD) and associated with a poor prognosis. Recently cardiac involvement…
Abstract Number: 2207 • 2018 ACR/ARHP Annual Meeting
Detecting Hand Joint Ankylosis in Radiographic Images Using Deep Learning: A Step in Development of Automatic Radiographic Scoring System for Bone Destruction
Keisuke Izumi^1,2, Masahiro Hashimoto³, Kanata Suzuki⁴, Toshio Endoh⁴, Kentaro Doi⁵, Yuki Iwai⁵, Masahiro Jinzaki³, Shigeru Ko⁶ and Tsutomu Takeuchi¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ³Department of Radiology, Keio University School of Medicine, Tokyo, Japan, ⁴Machine Learning Technology Project, Artificial Intelligence Laboratory, FUJITSU LABORATORIES LTD., Kawasaki, Japan, ⁵SOLUTIONS DEVELOPMENT DEPT.I, MEDICAL SOLUTIONS DIV.V, Healthcare Solutions Unit. II, FUJITSU LTD., Tokyo, Japan, ⁶Department of Systems Medicine, Keio University School of Medicine, Tokyo, Japan
Background/Purpose: Artificial intelligence (AI) techniques including deep learning have been rapidly evolving and shown good performance in many fields over recent years. However, there are…
Abstract Number: 2208 • 2018 ACR/ARHP Annual Meeting
Novel Fluorescence Optical Imaging Scoring System of Inflammation in the Hand and Wrist Is in Patients with Rheumatoid Arthritis – Agreement with Ultrasonography and Sensitivity to Change
Mads Ammitzbøll-Danielsen¹, Daniel Glinatsi¹, Lene Terslev² and Mikkel Østergaard^3,4, ¹Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ²Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ³Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Fluorescence optical imaging (FOI) has been used for assessment of inflammation in the hands and has in several cross sectional studies been compared with…
Abstract Number: 2321 • 2018 ACR/ARHP Annual Meeting
Dickkopf-1 Serum Levels in Patients with Systemic Sclerosis and Correlation with Trabecular Bone Score
Barbara Ruaro¹, Andrea Casabella², Sabrina Paolino¹, Carmen Pizzorni², Vanessa Smith³, Chiara Seriolo⁴, Luigi Molfetta⁴, Patrizio Odetti⁴ and Maurizio Cutolo², ¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genova, Italy, ²Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, San Martino Polyclinic Hospital, Genoa, Italy, Genoa, Italy, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Centro di Ricerca su Osteoporosi e Patologie Osteoarticolari CROPO, Di.M.I., Genoa, Italy, Genoa, Italy
Background/Purpose: Dickkopf-1 (DKK1) is a natural inhibitor of Wnt signaling pathway that could be involved in promoting osteoclastogenesis through suppression of osteoprotegerin (1,2). Systemic sclerosis…
Abstract Number: 2973 • 2017 ACR/ARHP Annual Meeting
Detection of Clinical Signs of Arthritis and Subclinical Evidence of Inflammation in Psoriasis Patients with Risk for Arthritis: Value of Clinical Examination, Ultrasound and Fluorescence-Optical Imaging – Results from the Prospective Multicentre Xciting Study
Michaela Koehm¹, Tanja Rossmanith², Hans-Eckhard Langer³, Marina Backhaus⁴, Gerd R. Burmester⁵, Siegfried Wassenberg⁶, Benjamin Köhler⁶, Harald Burkhardt⁷ and Frank Behrens⁸, ¹Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt/Main, Germany, ²Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Frankfurt, Germany, ³RHIO (Rheumatology, Immunology, Osteology) Duesseldorf, Duesseldorf, Germany, ⁴Rheumatology, Park-Klinik Weissensee, Berlin, Germany, ⁵Department of Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Free University and Humboldt University Berlin, Berlin, Germany, ⁶Rheumazentrum Ratingen, Ratingen, Germany, ⁷Division of Rheumatology and Fraunhofer IME-Project-Group Translational Medicine and Pharmacology, Goethe University, Frankfurt, Germany, ⁸Clinical Research Rheumatology and Fraunhofer Institute IMETranslation, Goethe University, Frankfurt, Germany
Background/Purpose: Psoriasis (Pso) is one of the most common chronic inflammatory skin diseases in Europe. Psoriatic arthritis (PsA) is closely associated to Pso whereas the…
Abstract Number: 248 • 2017 ACR/ARHP Annual Meeting
Validation of Objective Quantification System for Disease Progression in Patients with Juvenile Idiopathic Arthritis
Olga Kubassova¹, N Tzaribachev², Romiesa Hagoug³ and Mikael Boesen⁴, ¹R&D, Image Analysis Group, London, England, ²University Medical Center Schleswig-Holstein, Bad Bramstedt, Germany, ³Imaging, Image Analysis Group, London, United Kingdom, ⁴Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiskberg, Denmark
Background/Purpose: Imaging as outcome measure has been studied and extensively used in the assessment of treatment for adult patients with rheumatoid arthritis (RA)1. In children…
Abstract Number: 256 • 2017 ACR/ARHP Annual Meeting
Tracking Digital Ulcers in Systemic Sclerosis: Feasibility Study Assessing Lesion Area from Patient-Recorded Smartphone Photographs
Graham Dinsdale¹, Tonia Moore², Joanne Manning², Andrea Murray¹, Ross Atkinson³, Karen Ousey⁴, Mark Dickinson⁵, Christopher Taylor⁶ and Ariane L. Herrick^1,7, ¹Division of Musculoskeletal & Dermatological Sciences, University of Manchester, Salford Royal Hospital NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom, ²Salford Royal Hospital NHS Foundation Trust, Salford, UK, Salford, United Kingdom, ³School of Health Sciences, Division of Nursing, Midwifery & Social Work, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁴Division of Podiatry and Clinical Sciences, University of Huddersfield, Huddersfield, UK, Huddersfield, United Kingdom, ⁵Photon Science Institute, School of Physics and Astronomy, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁶Centre for Imaging Sciences, Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK, Manchester, United Kingdom, ⁷NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK, Manchester, United Kingdom
Background/Purpose: Approximately 50% of patients with systemic sclerosis (SSc) will develop painful digital (finger) ulcers (DUs) at some point during their disease course. These lesions…
Abstract Number: 592 • 2017 ACR/ARHP Annual Meeting
Which Imaging Outcomes for AxSpA Are Most Sensitive to Change? a 5-Year Analysis of the DESIR Cohort
Alexandre Sepriano¹, Sofia Ramiro², Désirée van der Heijde¹, Maxime Dougados³, Pascal Claudepierre⁴, Antoine Feydy⁵, M. Reijnierse⁶, Damien Loeuille⁷ and Robert B.M. Landewé⁸, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Department of Rheumatology, LUMC, Leiden, Netherlands, Leiden, Netherlands, ³Paris-Descartes University,, Paris, France, ⁴Hôpital Henri Mondor, Créteil, France, ⁵Univ. Paris Descartes, PRES Sorbonne Paris Cité, Service de radiologie B, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, Paris, France, ⁶Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, ⁸University of Amsterdam and Atrium Medical Center, Amsterdam, Netherlands
Background/Purpose: Several imaging outcomes have become available to assess inflammation and structural damage over time in patients with axial spondyloarthris (axSpA). However, no formal comparison…
Abstract Number: 791 • 2017 ACR/ARHP Annual Meeting
Aortic Dilatation in Patients with Large Vessel Vasculitis: A Longitudinal Case Control Study Using Positron Emission Tomography/Computed Tomography
Filippo Crescentini¹, Francesco Muratore², Lucia Spaggiari³, Giulia Pazzola¹, Luigi Boiardi¹, Nicolò Pipitone¹ and Carlo Salvarani⁴, ¹Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, ²Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio Emilia, Italy, ³Radiology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, ⁴Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy
Background/Purpose: To evaluate aortic diameter and predictors of aortic dilatation using FDG-PET/CT in a longitudinally followed cohort of patients with large vessel vasculitis (LVV) compared…

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