Abstracts tagged "IgG4 Related Disease"

Abstract Number: 1840 • ACR Convergence 2022
The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease Perform Lower Than Expected: Data from a Norwegian Cohort
Jens Vikse¹, Oyvind Midtvedt², Oyvind Molberg³, Bjørg Tilde Svanes Fevang⁴, Oyvind Palm², Torhild Garen², Katrine Brække Norheim⁵, Gunnstein Bakland⁶, Marianne Wallenius⁷ and Anna-Maria Hoffmann-Vold², ¹University of Bergen, Stavanger, Norway, ²Oslo University Hospital, Oslo, Norway, ³Oslo University Hospital, Oslo, Nepal, ⁴Haukeland University Hospital, Bergen, Norway, ⁵Stavanger University Hospital, Stavanger, Norway, ⁶University Hospital of North-Norway, Tromsø, Norway, ⁷St. Olav University Hospital, Trondheim, Norway
Background/Purpose: Milestones in the field of IgG4-related disease (IgG4-RD) include the 2011 Comprehensive Diagnostic Criteria (CDC), the 2019 ACR/EULAR classification criteria, and the recent identification…
Abstract Number: 0128 • ACR Convergence 2022
Advantages of Alternate-Day Glucocorticoid Treatment Strategy for IgG4-Related Disease: A Preliminary Retrospective Study ID: 1287015
Sho Fukui¹, Takehiro Nakai², Satoshi Kawaai³, Yukihiko Ikeda², Masei Suda⁴, Atsushi Nomura⁵, Hiromichi Tamaki², Mitsumasa Kishimoto⁶, Sachiko Ohde⁷ and Masato Okada², ¹Kyorin University Hospital, Tokyo, Japan, ²St. Luke's International Hospital, Tokyo, Japan, ³St. Luke's International Hospital, Chuo-ku, Tokyo, Japan, ⁴Suwa Central Hospital, Nagano, Japan, ⁵St. Luke's International Hospital, Nagareyama, Japan, ⁶Kyorin University School of Medicine, Yokohama, Japan, ⁷Center for Clinical Epidemiology, St.Luke's International University, Tokyo, Japan
Background/Purpose: Alternate-day glucocorticoid (GC) treatment is an effective treatment option that can reduce GC-associated adverse events in patients with rheumatoid arthritis and other autoimmune rheumatic…
Abstract Number: 0144 • ACR Convergence 2022
The Association of Hypocomplementemia with Organ Involvement and Serum IgG4 in IgG4-related Disease
Guy Katz¹, Amelia S. Cogan¹, Grace McMahon¹, Sebastian Perez-Espina¹, Ana Fernandes¹, Cory Perugino¹, Zachary Wallace¹, John Atkinson², Alfred Kim² and John Stone³, ¹Massachusetts General Hospital, Boston, MA, ²Washington University School of Medicine, St. Louis, MO, ³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA
Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease that can affect nearly every organ in the body. Hypocomplementemia is common in some patients with…
Abstract Number: 0147 • ACR Convergence 2022
Rituximab in IgG4-Related Diseae: An Open-Label Non-Randomized Observational Study
Jens Vikse¹, Oyvind Midtvedt², Oyvind Molberg³, Bjørg Tilde Svanes Fevang⁴, Oyvind Palm², Torhild Garen², Katrine Brække Norheim⁵, Gunnstein Bakland⁶, Marianne Wallenius⁷ and Anna-Maria Hoffmann-Vold², ¹University of Bergen, Stavanger, Norway, ²Oslo University Hospital, Oslo, Norway, ³Oslo University Hospital, Oslo, Nepal, ⁴Haukeland University Hospital, Bergen, Norway, ⁵Stavanger University Hospital, Stavanger, Norway, ⁶University Hospital of North-Norway, Tromsø, Norway, ⁷St. Olav University Hospital, Trondheim, Norway
Background/Purpose: IgG4-related disease (IgG4-RD) is a rare, heterogenous and potentially severe disease. An open-label trial demonstrated efficacy of rituximab (RTX) in IgG4-RD. Recently, four distinct…
Abstract Number: 0815 • ACR Convergence 2022
Hyper-IgG4 in Patients with Systemic Autoinflammatory Disease
Brianne Navetta-Modrov and QingPing Yao, Stony Brook University, Stony Brook, NY
Background/Purpose: Hyper-immunoglobulin G4 (IgG4) has been reported in various conditions including autoimmune disease, gastrointestinal disorders, lymphoproliferative/granulomatous diseases and solid tumors. IgG4-related disease is an immune-mediated…
Abstract Number: 0209 • ACR Convergence 2021
IgG4 Related Disease: Response to Immunosuppressive Therapy – A Single Centre Retrospective Study in the United Kingdom
Shirish Sangle¹, Neil Morton², Alina Casian², Louise Nel², Jennifer Hannah³ and David D'Cruz⁴, ¹Guy's and St Thomas' Hospital NHS Trust, London, United Kingdom, ²Guys and St Thomas' NHS Trust, London, United Kingdom, ³Kings College Hospital, London, United Kingdom, ⁴Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
Background/Purpose: IgG4 related disease (IgG4-RD) is a rare immune-mediated condition, increasingly being recognised as a multi-organ disorder. It is a relatively new entity and the…
Abstract Number: 0621 • ACR Convergence 2021
Case Series of IgG4-related Disease in African American Patients at Two Large Academic Centers
Jonathan Thaler¹, Sunita Dia² and Florina Constantinescu², ¹MedStar Georgetown University Hospital, Washington, DC, ²Medstar Washington Hospital Center, Washington, DC
Background/Purpose: IgG4-related Disease (IgG4-rD) is a fibroinflammatory disease with highly variable manifestations that can be difficult to diagnose. Response to treatment with prednisone and/or rituximab…
Abstract Number: 1102 • ACR Convergence 2021
Comorbidities and Causes of Hospitalizations in a Cohort of IgG4-Related Disease Patients from a Single Center
David Faz-Muñoz, Eduardo Martin-Nares, Alejandra Hernández-Delgado and Gabriela Hernandez-Molina, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: The frequency and types of comorbidities, causes of hospitalization, and the differences among clinical phenotypes in patients with IgG4-related disease (IgG4-RD) have not been…
Abstract Number: 1103 • ACR Convergence 2021
Disease Associations with Very High Serum IgG4 Concentrations: A Retrospective Multi-Center Study
Matthew Baker¹, Claire Cook², Xiaoqing Fu³, Cory Perugino³, John Stone⁴ and Zachary Wallace⁵, ¹Stanford University, Menlo Park, CA, ²Division of Rheumatology, Allergy, and Immunology, Mass General Hospital, Boston, MA, ³Massachusetts General Hospital, Boston, MA, ⁴Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ⁵Massachusetts General Hospital, Newton, MA
Background/Purpose: Serum IgG4 concentrations are used as part of the evaluation for suspected IgG4-related disease (IgG4-RD), but the specificity of this test, especially at very…
Abstract Number: 1113 • ACR Convergence 2021
Validation of the 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease in a Latin American Cohort
Eduardo Martin-Nares¹, Gabriela Hernandez-Molina¹, Diego Baenas², Jesús Delgado-de la Mora³, Francisco Caeiro⁴, Pamela Wurmann Kiblisky⁵, Victor Pimentel-Quiroz⁶, Valery Ascuña Valdivia⁷, David Faz-Muñoz¹, Emanuel Saad⁸, Ernesto Cairoli⁹, Sergio Elgueta Pinochet¹⁰, Hugo Madariaga Charaja¹¹, Daniel Montante-Montes de Oca³, Jesica Gallo¹², Manuel Ugarte-Gil⁶, Oscar Neira¹³, Paula Burgos¹⁴ and Sergio Paira¹⁵, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, ³Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁴Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, ⁵Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago, Chile, ⁶Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, ⁷Uveitis and Inflammatory Eye Diseases Area, Instituto Oftalmosalud, Arequipa, Peru, ⁸Departamento de Clínica Médica, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, ⁹Autoimmune Diseases Unit, Centro Asistencial del Sindicato Médico del Uruguay (CASMU) and Hospital Evangélico, Montevideo, Uruguay, ¹⁰Departamento de Medicina, Sección Reumatología, Hospital Clínico de la Universidad de Chile, Santiago, Chile, ¹¹Rheumatology Department, Hospital Essalud Yanahuara, Arequipa, Peru, ¹²Sección de Reumatología, Hospital Central de Reconquista, Reconquista, Argentina, ¹³Hospital del Salvador, Universidad de ChileSección Reumatología, Hospital del Salvador, Universidad de Chile, Santiago, Chile, ¹⁴Departamento de Inmunología Clínica y Reumatología, Pontificia Universidad Católica de Chile, Santiago, Chile, ¹⁵Sección de Reumatología, Hospital José María Cullen, Santa Fe, Argentina
Background/Purpose: The 2019 ACR/EULAR classification criteria (2019 AECC) for IgG4-related disease (IgG4-RD) have been validated in cohorts mainly composed of Caucasian and Asian patients. Its…
Abstract Number: 1879 • ACR Convergence 2021
Delayed Diagnosis of IgG4 Related Disease Is Associated with Worse Outcome: A Retrospective, Real-life Observational Study
Elisheva Pokroy-Shapira¹, Iftach Sagy², Katya Meridor³ and Yair Molad⁴, ¹Institute of Rheumatology, Rabin Medical Center, Beilinson Hospital, and Tel Aviv University, Petach Tikva, Israel, ²Clinical Research Center, Soroka University Medical Center, Beer Sheva and Ben Gurion University of the Negev, DVIRA, Israel, ³Tel Aviv Sourasky Medical Center, Kfar Saba, Israel, ⁴Rabin Medical Center, Beilinson Hospital, and Tel Aviv University, Petah-Tikva, Israel
Background/Purpose: The purpose of this study was to characterize clinical and pathological features as well as disease outcome of an Israeli incident cohort of patients…
Abstract Number: 1888 • ACR Convergence 2021
Usefulness of 2019 ACR/EULAR Classification Criteria (AECC) for IgG4-Related Disease Differs Between Clinical Phenotypes of IgG4-RD
Gözde Kübra Yardımcı¹, Bayram Farisogulları², Gizem Ayan¹, Levent Kilic¹, Sule Apraş Bilgen¹ and Omer Karadag³, ¹Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ²Division of Rheumatology, Department of Internal Medicine Faculty of Medicine, Hacettepe University, Ankara, Turkey, ³Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey
Background/Purpose: ACR/EULAR Classification criteria for IgG4-related disease (IgG4-RD) newly published [1]. On the other hand, four distinctive phenotypes of IgG4-RD have been described [2]. We…
Abstract Number: 0078 • ACR Convergence 2020
Retrospective Analysis of Clinical Characteristics and Classification Criteria Performance in a Single Center Cohort of 114 Patients Diagnosed with IgG4-Related Disease
Robert Spandorfer¹, Madiha Ahmad² and Arezou Khosroshahi³, ¹Emory University School of Medicine, Atlanta, GA, ²Emory University, Decatur, ³Emory University, Atlanta, GA
Background/Purpose: Immunoglobulin G4 Related Disease (IgG4-RD) is a fibroinflammatory condition that can involve almost any organ system. Diagnosis is made based on correlation of clinical,…
Abstract Number: 0416 • ACR Convergence 2020
IgG4-related Retroperitoneal Fibrosis. Retrospective Cohort
Ernestina Angarola¹, Federico Jauk², Verónica Peuchot³, Maria Orlova¹, Melina Valeo², Javier Pollan¹ and Hernán Garcia Rivello², ¹Department of Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ²Department of Pathology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ³Internal Medicine Research Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
Background/Purpose: The spectrum of IgG4-related disease (IgG4-RD) includes many diseases that were thought to be confined to a single organ, as the retroperitoneal fibrosis. Many…
Abstract Number: 0417 • ACR Convergence 2020
Different Immunophenotypes Characterized IgG4-Related Disease Clinical Phenotypes
Eduardo Martin-Nares¹, Janette Furuzawa-Carballeda¹, Ángel Alexis Priego-Ranero¹, Isela Chan-Campos¹, Gladys Sulikey Herrera-Noguera¹, Fidel López-Verdugo¹ and Gabriela Hernandez-Molina¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Distrito Federal, Mexico
Background/Purpose: Patients with IgG4-related disease (IgG4-RD) can be classified in clinical phenotypes which differ in terms of demographics, clinical and serological features. Whether there are…

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