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Abstracts tagged "IgG4 Related Disease"

  • Abstract Number: 0128 • ACR Convergence 2022

    Advantages of Alternate-Day Glucocorticoid Treatment Strategy for IgG4-Related Disease: A Preliminary Retrospective Study ID: 1287015

    Sho Fukui1, Takehiro Nakai2, Satoshi Kawaai3, Yukihiko Ikeda2, Masei Suda4, Atsushi Nomura5, Hiromichi Tamaki2, Mitsumasa Kishimoto6, Sachiko Ohde7 and Masato Okada2, 1Kyorin University Hospital, Tokyo, Japan, 2St. Luke's International Hospital, Tokyo, Japan, 3St. Luke's International Hospital, Chuo-ku, Tokyo, Japan, 4Suwa Central Hospital, Nagano, Japan, 5St. Luke's International Hospital, Nagareyama, Japan, 6Kyorin University School of Medicine, Yokohama, Japan, 7Center for Clinical Epidemiology, St.Luke's International University, Tokyo, Japan

    Background/Purpose: Alternate-day glucocorticoid (GC) treatment is an effective treatment option that can reduce GC-associated adverse events in patients with rheumatoid arthritis and other autoimmune rheumatic…
  • Abstract Number: 0144 • ACR Convergence 2022

    The Association of Hypocomplementemia with Organ Involvement and Serum IgG4 in IgG4-related Disease

    Guy Katz1, Amelia S. Cogan1, Grace McMahon1, Sebastian Perez-Espina1, Ana Fernandes1, Cory Perugino1, Zachary Wallace1, John Atkinson2, Alfred Kim2 and John Stone3, 1Massachusetts General Hospital, Boston, MA, 2Washington University School of Medicine, St. Louis, MO, 3Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease that can affect nearly every organ in the body. Hypocomplementemia is common in some patients with…
  • Abstract Number: 0147 • ACR Convergence 2022

    Rituximab in IgG4-Related Diseae: An Open-Label Non-Randomized Observational Study

    Jens Vikse1, Oyvind Midtvedt2, Oyvind Molberg3, Bjørg Tilde Svanes Fevang4, Oyvind Palm2, Torhild Garen2, Katrine Brække Norheim5, Gunnstein Bakland6, Marianne Wallenius7 and Anna-Maria Hoffmann-Vold2, 1University of Bergen, Stavanger, Norway, 2Oslo University Hospital, Oslo, Norway, 3Oslo University Hospital, Oslo, Nepal, 4Haukeland University Hospital, Bergen, Norway, 5Stavanger University Hospital, Stavanger, Norway, 6University Hospital of North-Norway, Tromsø, Norway, 7St. Olav University Hospital, Trondheim, Norway

    Background/Purpose: IgG4-related disease (IgG4-RD) is a rare, heterogenous and potentially severe disease. An open-label trial demonstrated efficacy of rituximab (RTX) in IgG4-RD. Recently, four distinct…
  • Abstract Number: 0815 • ACR Convergence 2022

    Hyper-IgG4 in Patients with Systemic Autoinflammatory Disease

    Brianne Navetta-Modrov and QingPing Yao, Stony Brook University, Stony Brook, NY

    Background/Purpose: Hyper-immunoglobulin G4 (IgG4) has been reported in various conditions including autoimmune disease, gastrointestinal disorders, lymphoproliferative/granulomatous diseases and solid tumors. IgG4-related disease is an immune-mediated…
  • Abstract Number: 1570 • ACR Convergence 2022

    Memory CD4+T Cell Signature Is Associated with Unfavorable Prognosis in IgG4-related Disease: Risk Stratification by Machine-learning

    Yuxue Nie1, zheng liu1, Wei Cao2, Taisheng Li2 and Wen Zhang3, 1Department of Rheumatology, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 2Department of Infectious Diseases, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 3Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: IgG4-related disease (IgG4-RD) is a chronic immune-mediated disease with significant heterogeneity. A better understanding of the variance in the immune signature of IgG4-RD will…
  • Abstract Number: 1571 • ACR Convergence 2022

    Coronary Arteritis and Periarteritis Secondary to IgG4-related Disease in a Large, Single-center Cohort

    Guy Katz1, sandeep hedgire1, James Stone2, Sebastian Perez-Espina1, Ana Fernandes1, Cory Perugino1, Zachary Wallace1 and John Stone3, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Reading, MA, 3Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic autoimmune fibroinflammatory disease capable of affecting most organ systems. Large-vessel vasculitis is a well-described manifestation of the disease.…
  • Abstract Number: 1576 • ACR Convergence 2022

    Clinical Presentation and Outcome of Patients with Chronic Abdominal Periaortitis

    Umar Ghaffar1, Hannah Langenfeld2, Cynthia Crowson3, Tanaz Kermani4, Michelle Burke1, Boyd Viers1, Aaron Potretzke1, Haraldur Bjarnason1, Kenneth J. Warrington1 and Matthew J. Koster1, 1Mayo Clinic, Rochester, MN, 2Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, 3Mayo Clinic, Eyota, MN, 4University of California Los Angeles, West Hills, CA

    Background/Purpose: To evaluate the presentation features and outcomes of patients with chronic abdominal periaortitis in a large referral cohort. Methods: Using a proprietary medical text…
  • Abstract Number: 1840 • ACR Convergence 2022

    The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease Perform Lower Than Expected: Data from a Norwegian Cohort

    Jens Vikse1, Oyvind Midtvedt2, Oyvind Molberg3, Bjørg Tilde Svanes Fevang4, Oyvind Palm2, Torhild Garen2, Katrine Brække Norheim5, Gunnstein Bakland6, Marianne Wallenius7 and Anna-Maria Hoffmann-Vold2, 1University of Bergen, Stavanger, Norway, 2Oslo University Hospital, Oslo, Norway, 3Oslo University Hospital, Oslo, Nepal, 4Haukeland University Hospital, Bergen, Norway, 5Stavanger University Hospital, Stavanger, Norway, 6University Hospital of North-Norway, Tromsø, Norway, 7St. Olav University Hospital, Trondheim, Norway

    Background/Purpose: Milestones in the field of IgG4-related disease (IgG4-RD) include the 2011 Comprehensive Diagnostic Criteria (CDC), the 2019 ACR/EULAR classification criteria, and the recent identification…
  • Abstract Number: 0209 • ACR Convergence 2021

    IgG4 Related Disease: Response to Immunosuppressive Therapy – A Single Centre Retrospective Study in the United Kingdom

    Shirish Sangle1, Neil Morton2, Alina Casian2, Louise Nel2, Jennifer Hannah3 and David D'Cruz4, 1Guy's and St Thomas' Hospital NHS Trust, London, United Kingdom, 2Guys and St Thomas' NHS Trust, London, United Kingdom, 3Kings College Hospital, London, United Kingdom, 4Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom

    Background/Purpose: IgG4 related disease (IgG4-RD) is a rare immune-mediated condition, increasingly being recognised as a multi-organ disorder. It is a relatively new entity and the…
  • Abstract Number: 0621 • ACR Convergence 2021

    Case Series of IgG4-related Disease in African American Patients at Two Large Academic Centers

    Jonathan Thaler1, Sunita Dia2 and Florina Constantinescu2, 1MedStar Georgetown University Hospital, Washington, DC, 2Medstar Washington Hospital Center, Washington, DC

    Background/Purpose: IgG4-related Disease (IgG4-rD) is a fibroinflammatory disease with highly variable manifestations that can be difficult to diagnose. Response to treatment with prednisone and/or rituximab…
  • Abstract Number: 1102 • ACR Convergence 2021

    Comorbidities and Causes of Hospitalizations in a Cohort of IgG4-Related Disease Patients from a Single Center

    David Faz-Muñoz, Eduardo Martin-Nares, Alejandra Hernández-Delgado and Gabriela Hernandez-Molina, Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: The frequency and types of comorbidities, causes of hospitalization, and the differences among clinical phenotypes in patients with IgG4-related disease (IgG4-RD) have not been…
  • Abstract Number: 1103 • ACR Convergence 2021

    Disease Associations with Very High Serum IgG4 Concentrations: A Retrospective Multi-Center Study

    Matthew Baker1, Claire Cook2, Xiaoqing Fu3, Cory Perugino3, John Stone4 and Zachary Wallace5, 1Stanford University, Menlo Park, CA, 2Division of Rheumatology, Allergy, and Immunology, Mass General Hospital, Boston, MA, 3Massachusetts General Hospital, Boston, MA, 4Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, 5Massachusetts General Hospital, Newton, MA

    Background/Purpose: Serum IgG4 concentrations are used as part of the evaluation for suspected IgG4-related disease (IgG4-RD), but the specificity of this test, especially at very…
  • Abstract Number: 1113 • ACR Convergence 2021

    Validation of the 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease in a Latin American Cohort

    Eduardo Martin-Nares1, Gabriela Hernandez-Molina1, Diego Baenas2, Jesús Delgado-de la Mora3, Francisco Caeiro4, Pamela Wurmann Kiblisky5, Victor Pimentel-Quiroz6, Valery Ascuña Valdivia7, David Faz-Muñoz1, Emanuel Saad8, Ernesto Cairoli9, Sergio Elgueta Pinochet10, Hugo Madariaga Charaja11, Daniel Montante-Montes de Oca3, Jesica Gallo12, Manuel Ugarte-Gil6, Oscar Neira13, Paula Burgos14 and Sergio Paira15, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 2Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, 3Department of Pathology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Servicio de Reumatología, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 5Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago, Chile, 6Hospital Guillermo Almenara Irigoyen, Essalud/Universidad Científica del Sur, Lima, Peru, 7Uveitis and Inflammatory Eye Diseases Area, Instituto Oftalmosalud, Arequipa, Peru, 8Departamento de Clínica Médica, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, 9Autoimmune Diseases Unit, Centro Asistencial del Sindicato Médico del Uruguay (CASMU) and Hospital Evangélico, Montevideo, Uruguay, 10Departamento de Medicina, Sección Reumatología, Hospital Clínico de la Universidad de Chile, Santiago, Chile, 11Rheumatology Department, Hospital Essalud Yanahuara, Arequipa, Peru, 12Sección de Reumatología, Hospital Central de Reconquista, Reconquista, Argentina, 13Hospital del Salvador, Universidad de ChileSección Reumatología, Hospital del Salvador, Universidad de Chile, Santiago, Chile, 14Departamento de Inmunología Clínica y Reumatología, Pontificia Universidad Católica de Chile, Santiago, Chile, 15Sección de Reumatología, Hospital José María Cullen, Santa Fe, Argentina

    Background/Purpose: The 2019 ACR/EULAR classification criteria (2019 AECC) for IgG4-related disease (IgG4-RD) have been validated in cohorts mainly composed of Caucasian and Asian patients. Its…
  • Abstract Number: 1879 • ACR Convergence 2021

    Delayed Diagnosis of IgG4 Related Disease Is Associated with Worse Outcome: A Retrospective, Real-life Observational Study

    Elisheva Pokroy-Shapira1, Iftach Sagy2, Katya Meridor3 and Yair Molad4, 1Institute of Rheumatology, Rabin Medical Center, Beilinson Hospital, and Tel Aviv University, Petach Tikva, Israel, 2Clinical Research Center, Soroka University Medical Center, Beer Sheva and Ben Gurion University of the Negev, DVIRA, Israel, 3Tel Aviv Sourasky Medical Center, Kfar Saba, Israel, 4Rabin Medical Center, Beilinson Hospital, and Tel Aviv University, Petah-Tikva, Israel

    Background/Purpose: The purpose of this study was to characterize clinical and pathological features as well as disease outcome of an Israeli incident cohort of patients…
  • Abstract Number: 1888 • ACR Convergence 2021

    Usefulness of 2019 ACR/EULAR Classification Criteria (AECC) for IgG4-Related Disease Differs Between Clinical Phenotypes of IgG4-RD

    Gözde Kübra Yardımcı1, Bayram Farisogulları2, Gizem Ayan1, Levent Kilic1, Sule Apraş Bilgen1 and Omer Karadag3, 1Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 2Division of Rheumatology, Department of Internal Medicine Faculty of Medicine, Hacettepe University, Ankara, Turkey, 3Hacettepe University, Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Ankara, Turkey

    Background/Purpose: ACR/EULAR Classification criteria for IgG4-related disease (IgG4-RD) newly published [1]. On the other hand, four distinctive phenotypes of IgG4-RD have been described [2]. We…
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