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Abstracts tagged "HLA-SE"

  • Abstract Number: 0519 • ACR Convergence 2021

    The Relationship of Genetics and Clinically Suspect Arthralgia in RA Development Assessed Using HC, CSA and RA Patients

    Marc Maurits, Fenne Wouters, Ellis Niemantsverdriet, Tom WJ Huizinga, Annette H.M van der Helm-van Mil and Rachel Knevel, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The identification of a pre-RA stage of patients with clinically suspect arthralgia (CSA) has proven to be beneficial in the early detection of Rheumatoid…
  • Abstract Number: 0522 • ACR Convergence 2021

    Genetics of Rheumatoid Arthritis Remission; HLA-SE Associated with Remission in Anti-CCP Positive Patients

    Marc Maurits1, Samantha Jurado Zapata1, Yann Abraham2, Erik van den Akker1, Anne Barton3, Philip Brown4, Andrew P Cope5, Isidoro Gonzalez-Alvaro6, Carl Goodyear7, Annette H.M van der Helm-van Mil1, Xinli Hu8, Tom WJ Huizinga1, Martina Johannesson9, Lars Klareskog10, Dennis Lendrem11, Iain McInnes12, Fraser Morton7, Caron Paterson7, Duncan Porter13, Arthur Pratt11, Luis Rodriguez Rodriguez14, Daniela Sieghart15, Paul Studenic16, Suzanne Verstappen17, Leonid Padyukov9, Aaron Winkler18, John Isaacs19 and Rachel Knevel1, 1Leiden University Medical Center, Leiden, Netherlands, 2Janssen Pharmaceutical Companies of Johnson & Johnson, Beerse, Belgium, 3University of Manchester, Manchester, United Kingdom, 4Newcastle University, Newcastle, United Kingdom, 5King's College London, London, United Kingdom, 6Rheumatology Service. La Princesa University Hospital, Madrid, Spain, 7University of Glasgow, Glasgow, United Kingdom, 8Pfizer, Saint Peters, MO, 9Karolinska Institutet, Stockholm, Sweden, 10Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 11Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom, 12University of Glasgow, School of Medicine, Glasgow, Scotland, United Kingdom, 13University of Glasgow, Bearsden, United Kingdom, 14Hospital Clinico San Carlos, Madrid, Spain, 15Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 16Karolinska Institute; & Medical University of Vienna, Stockholm, Sweden, 17School of Social Sciences, The University of Manchester, Manchester, United Kingdom, 18Pfizer, Cambridge, MA, 19Newcastle University, Newcastle upon Tyne, United Kingdom

    Background/Purpose: Rheumatoid Arthritis (RA) patients capable of reaching clinical remission potentially have a specific genetic profile that allows them to regain immune tolerance. The identification…

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