Abstracts tagged "Hepatitis"

Abstract Number: 2454 • 2018 ACR/ARHP Annual Meeting
Virus Reactivation Rate in Rheumatoid Arthritis Using Tofacitinib
Yukitomo Urata, Rheumatology, Tsugaru General Hospital, United Municipalities of Tsugaru, Gosyogawara, Japan
Background/Purpose: Although the increase in the incidence of Herpes Zoster by tofacitinib(TOF) in rheumatoid arthritis (RA) is well known, the reactivation rate of other viruses…
Abstract Number: 369 • 2017 ACR/ARHP Annual Meeting
Hepatitis A Virus Vaccination in Juvenile-Onset Systemic Lupus Erythematosus
Sevinc Mertoglu¹, Sezgin Sahin¹, Omer Faruk Beser², Amra Adrovic¹, Kenan Barut¹, Pelin Yuksel³, Soner Sazak⁴, Bekir Kocazeybek⁵ and Ozgur Kasapcopur¹, ¹Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ²Pediatric Gastroenterology, Department of Pediatrics, Okmeydani Education and Training Hospital, Istanbul, Turkey, ³Microbiology, Istanbul University, Cerrahpasa Medical School, Department of Microbiology, Istanbul, Turkey, ⁴Pediatrics, Department of Pediatrics, Okmeydani Education and Training Hospital, Istanbul, Turkey, ⁵Istanbul University, Cerrahpasa Medical School, Department of Microbiology, Istanbul, Turkey
Background/Purpose: Various infections play significant roles in flares of systemic lupus erythematosus (SLE). Hepatitis A virus is one of these infectious agents that has high…
Abstract Number: 384 • 2017 ACR/ARHP Annual Meeting
Protection Against Hepatitis B in Immunocompromised Pediatric Rheumatology and Gastroenterology Patients
Najla Aljaberi¹, Emily A. Smitherman², Enas Ghulam³, Allen Watts², Dana MH Dykes⁴ and Jennifer L. Huggins⁵, ¹Pediatric rheumatology, Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Environmental health and biostatistics, Department of Environmental Health, University of Cincinnati, Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ⁴Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Hepatitis B infection remains a significant public health challenge, particularly for patients on chronic immunosuppressive therapy, due to a considerable mortality risk associated with…
Abstract Number: 385 • 2017 ACR/ARHP Annual Meeting
Reliable Implementation of a Hepatitis B Serology Screening and Vaccination Process for Immunocompromised Pediatric Rheumatology Patients
Emily A. Smitherman¹, Adam Furnier², Allen Watts¹, Sandra Kramer¹, Elizabeth Joy Baker¹, Dana MH Dykes³, Rebecca Brady⁴ and Jennifer L. Huggins⁵, ¹Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Vaccine-preventable infections, including reactivation of hepatitis B virus, are a leading cause of morbidity and mortality in immunocompromised patients. Guidelines recommend that all immunosuppressed…
Abstract Number: 1099 • 2017 ACR/ARHP Annual Meeting
Hepatitis B Reactivation in Rheumatologic Patients
Yassir Daghistani¹, Fergus To², Patrick Doyle^3,4, Hin Hin Ko⁵, Mel Krajden^3,4, Jason Kur², Alnoor Ramji⁶, Kam Shojania², Edward Tam⁵, John Wade², Eric Yoshida⁵, Graham Reid², Siegfried Erb⁵ and Mollie Carruthers², ¹Medicine, University of British Columbia, Vancouver, BC, Canada, ²Rheumatology, University of British Columbia, Vancouver, BC, Canada, ³Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada, ⁴BC Centre for Disease Control, Vancouver, BC, Canada, ⁵Gastroenterology, University of British Columbia, Vancouver, BC, Canada, ⁶Gatroenterology, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: The widespread usage of biologic disease modifying anti-rheumatic drugs (bDMARDs) in rheumatology has increased the risk of hepatitis B virus (HBV) re-activation. The prevalence…
Abstract Number: 2385 • 2017 ACR/ARHP Annual Meeting
High Incidence of Hepatitis Related to HBV Reactivation in Rheumatoid Arthritis Patients with Resolved Hepatitis B Infection during Rituximab Treatment
Ming-Han Chen¹, Yen-Po Tsao², Yi-Hsiang Huang³, Chung-Tei Chou⁴ and Chang Youh Tsai², ¹Division of Allergy- Immunology- Rheumatology, Department of Medicine, Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ²Division of Allergy- Immunology- Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ³Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ⁴Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
AbstractBackground/Purpose: Rituximab-based chemotherapy can induce hepatitis B virus (HBV) reactivation (HBVr) in patients with hematological malignancies who have been exposed to HBV infection. However, informative…
Abstract Number: 10 • 2016 ACR/ARHP Annual Meeting
The Utility of Screening for Infectious Diseases in Recipients of Anti-TNF-α Therapy
Kristal Choi¹, Lester Mertz², Russell Heigh³, James Yiannias⁴ and Janis Blair⁵, ¹Internal Medicine, Mayo Clinic Arizona, Scottsdale, AZ, ²Rheumatology, Mayo Clinic Arizona, Scottsdale, AZ, ³Gastroenterology, Mayo Clinic Arizona, Scottsdale, AZ, ⁴Dermatology, Mayo Clinic Arizona, Scottsdale, AZ, ⁵Infectious Diseases, Mayo Clinic Arizona, Scottsdale, AZ
The Utility of Screening for Infectious Diseases in Recipients of Anti-TNF-α Therapy Choi, Kristal, Mertz, Lester, Heigh, Russell, Yiannias, James, Blair, Janis Background/Purpose: Tumor…
Abstract Number: 431 • 2016 ACR/ARHP Annual Meeting
Wide Variations in Hepatitis B Screening Practices for Patients Receiving Rituximab
Gabriela Schmajuk¹, Chris Tonner², Laura Trupin³, Jing Li⁴ and Jinoos Yazdany³, ¹San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA, ²Rheumatology, University of California, San Francisco, San Francisco, CA, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ⁴University of California, San Francisco, San Francisco, CA
Background/Purpose: Hepatitis B reactivation in the setting of rituximab use is a potentially fatal but preventable event. The rate of hepatitis B screening in patients…
Abstract Number: 433 • 2016 ACR/ARHP Annual Meeting
The Prevalence of Latent Tuberculosis and Hepatitis B Found after Systematic Screening of Patients Starting with Biological Therapy in a Low-Endemic Area
Marin de Jong^1,2, Danielle Roosen¹, Andy Peters¹, Valerie Verstraeten³, Marieke Pierik¹ and A. van Tubergen⁴, ¹Department of Internal Medicine, division of Gastroenterology, Maastricht University Medical Centre, Maastricht, Netherlands, ²NUTRIM – School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Maastricht, Netherlands, ³Department of Dermatology, Maastricht University Medical Centre, Maastricht, Netherlands, ⁴Department of Internal Medicine, Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Biologicals are a powerful treatment option for moderate to severe immune-mediated inflammatory diseases (IMID). Since biologicals modulate the immune system, the risk for reactivation…
Abstract Number: 502 • 2015 ACR/ARHP Annual Meeting
Decreased Vaccine Responses in Rheumatoid Arthritis Patients Receiving Anti-TNF Treatment and Relationship to B Cell Subsets
Jennifer Barnard¹, Nida Meednu², Kelly Callahan¹, Karen Boyle³, Lynette Keyes-Elstein³, Beverly Welch⁴, Ellen Goldmuntz⁵ and Jennifer H. Anolik¹, ¹University of Rochester Medical Center, Rochester, NY, ²Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ³Rho Federal Systems, Inc., Chapel Hill, NC, ⁴6610 Rockledge Dr., NIAID/NIH, Bethesda, MD, ⁵DAIT, NIAID/NIH, Bethesda, MD
Background/Purpose: TNF is a key pro-inflammatory cytokine in normal immune responses and pathologically in the rheumatoid arthritis (RA) synovium, thus representing a key treatment target…
Abstract Number: 1358 • 2015 ACR/ARHP Annual Meeting
Detection of a Unique Viral Infection in Salivary Glands of Sjögren’s Syndrome Patients and Viral-Mediated Recapitulation of Disease in Vivo
Melodie Weller¹, Matthew Gardner¹, Zoe Bogus¹, Michael Smith¹, Elisa Astorri², Drew Michael¹, Changyu Zheng¹, Peter Burbelo³, Paul A. Wilson⁴, Zhennan Lai¹, Bill Swaim¹, Beverly Handelman¹, Sandra Afione¹, Michele Bombardieri² and John A. Chiorini¹, ¹Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, ²Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom, ³Clinical Dental Research Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, ⁴National Intramural Database, Division of Enterprise and Custom Applications, Center for Information Technology, National Institutes of Health, Bethesda, MD
Background/Purpose: A viral infection is thought to be one of the triggers in the development of primary Sjögren’s syndrome (pSS). Multiple studies have shown stimulation…
Abstract Number: 1576 • 2015 ACR/ARHP Annual Meeting
Effect of Conventional Synthetic and Biological Disease Modifying Anti-Rheumatic Drugs on the Immunogenicity of Hepatitis B Vaccine in Patients with Rheumatoid Arthritis
Samanan Intongkam¹, Rattapol Pakchotanon², Sumapa Chaiamnuay², Paijit Asavatanabodee² and Pongthorn Narongroeknawin², ¹Internal medicine, Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand, ²Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand
Background/Purpose: Immunogenicity of pneumococcal and influenza vaccine in patients with rheumatoid arthritis (RA) have been assessed in many studies. However, the humoral immune response of…
Abstract Number: 484 • 2014 ACR/ARHP Annual Meeting
Reactivation of Hepatitis B Virus in Patients with Rheumatoid Arthritis after Anti-TNF Therapy
Seung Min Jung¹, Hong Ki Min¹, Jung Hee Koh¹, Jin Young Kang¹, Jennifer Lee¹, Seung-Ki Kwok², Ji Hyeon Ju¹, Hyeok-Jae Ko³, Kyung-Su Park⁴, Ho-Youn Kim¹ and Sung-Hwan Park¹, ¹Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, St. Mary’s hospital, The Catholic University of Korea, Seoul, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Daejeon, South Korea, ⁴Internal Medicine, St. Vincent Hospital, SuWon Gyeonggi-do, South Korea
Background/Purpose: Anti-TNF therapy was known to increase the risk of certain infection. There are only limited data about the reactivation of hepatitis B virus (HBV)…
Abstract Number: 483 • 2014 ACR/ARHP Annual Meeting
Risk of HBV Reactivation in Rheumatoid Arthritis Patients Undergoing Treatment with Newer Biological Dmards, Tocilizumab and Abatacept: A Single-Center Real Life Experience
Francesca De Nard¹, Vittorio Grosso², Monica Todoerti³, Carlomaurizio Montecucco⁴ and Roberto Caporali⁵, ¹Division of Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, ²Division of Rheumatology, University of Pavia, Foundation IRCCS Policlinico S. Matteo, Pavia, Italy, ³Rheumatology, University of Pavia, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, ⁴Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy, ⁵Division of Rheumatology, Rheumatology and Translational Immunology Research Laboratories (LaRIT), Division of Rheumatology, IRCCS Policlinico S.Matteo Foundation/University of Pavia, Pavia, Italy
Background/Purpose HBV infection represents a major issue in patients with rheumatoid arthritis (RA) undergoing biological disease-modifying anti-rheumatic drugs (bDMARDs) (1). While the risk of hepatitis…
Abstract Number: 2164 • 2014 ACR/ARHP Annual Meeting
Self-Phospholipids Regulate Inflammation Via Activation of CD1d-Restricted T-cells and Induction of ‘anti-inflammatory’ Myeloid-Derived Suppressor Cells (MDSC)
Ram Raj Singh^1,2,3,4, Cynthia Tran¹, Priti Prasad¹, Jing Wang⁵, Dirk Zajonc⁵ and Ramesh Halder¹, ¹Autoimmunity and Tolerance Laboratory, Department of Medicine/Rheumatology, UCLA, Los Angeles, CA, ²Interdepartmental Program in Molecular Toxicology, UCLA, Los Angeles, CA, ³Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA, ⁴Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ⁵La Jolla Institute of Allergy and Immunology, La Jolla, CA
Background/Purpose Self-lipids play an increasingly appreciated role in immunity and inflammation. Lipid antigens are presented by CD1d and CD1a-d molecules in mouse and human, respectively,…

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