Abstracts tagged "Heart disease"

Abstract Number: 2934 • 2018 ACR/ARHP Annual Meeting
Myocardial Microscopic Fibrosis Assessed By T1 Mapping Sequences on Cardiac Magnetic Resonance Imaging Predicts Cardiac Events in Systemic Sclerosis: Data from a Prospective Cohort Study on 40 Patients
Benjamin Terrier¹, Agnès Dechartres², Hervé Gouya³, Alexis Régent⁴, Bertrand Dunogué⁵, Pascal Cohen⁶, Alice Berezne⁷, Claire Le Jeunne⁸, Paul Legmann³, Olivier Vignaux³ and Luc Mouthon⁹, ¹National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France, ²Epidemiology, Hotel Dieu, Paris, France, ³Radiology, Cochin hospital, Paris, France, ⁴Department of Internal Medicine, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes, Paris, France, ⁵Internal Medicine, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁶Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, Hôpital Cochin, Université Paris Descartes, Sorbonne Paris Cité, Paris, France, ⁷Internal Medicine, CH Annecy, Annecy, France, ⁸Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, ⁹Department of Internal Medicine, INSERM Unité 1016, Centre de Référence pour les Maladies Auto-immunes Rares, National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France
Background/Purpose: Studies have shown that myocardial involvement may occur in systemic sclerosis (SSc) and lead to cardiac failure. We showed previously that cardiac magnetic resonance…
Abstract Number: 123 • 2018 ACR/ARHP Annual Meeting
Non-Hematopoietic Derived TNF Drives Pulmonary Vasculopathy: A New Model of CTD-Associated Pulmonary Hypertension
Richard Bell¹, Maria de la Luz Garcia-Hernandez², Javier Rangel-Moreno³, Christopher T. Ritchlin², Homaira Rahimi⁴ and Edward Schwarz⁵, ¹Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ²Division of Allergy/Immunology and Rheumatology and Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester Medical School, Rochester, New York, USA, Rochester, NY, ³Division of Allergy, Immunology and Rheumatology and Center for Musculoskeletal Research School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, ⁴Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY
Background/Purpose: Cardiopulmonary disease is a severe comorbidity in many connective tissue diseases (CTD). Rheumatoid arthritis, systemic sclerosis, and systemic lupus patients are all at increased…
Abstract Number: 496 • 2018 ACR/ARHP Annual Meeting
Heart Failure Risk Among Patients with Rheumatoid Arthritis: Association with Anti-Rheumatic Drugs
Michael Ahlers¹, C. Michael Stein², Cecilia P. Chung², Michelle J. Ormseth³, Eric Farber-Eger³ and Deepak Gupta⁴, ¹4906 illinois avenue, Vanderbilt University School of Medicine, Nashville, TN, ²Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, ³Vanderbilt University Medical Center, Nashville, TN, ⁴Internal Medicine - Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased risk of coronary artery disease (CAD), but the association with heart failure (HF) is less characterized. We…
Abstract Number: 507 • 2018 ACR/ARHP Annual Meeting
Echocardiographic Markers of Right Ventricle Dysfunction in Hispanic Patients with Rheumatoid Arthritis: A Case-Control Study
José R. Azpiri-López¹, Dionicio A. Galarza-Delgado², Iris J. Colunga-Pedraza³, Jose A. Davila-Jimenez⁴, Estefania E. Abundis-Marquez⁴, Andres H. Guillen-Lozoya⁴, Francisco J. Torres-Quintanilla⁴, Aldo Valdovinos-Bañuelos⁴, Ray Ramos-Cázares⁴, Raymundo Vera-Pineda⁴, Jesus A. Cardenas-de la Garza⁴, Rosa I. Arvizu-Rivera⁴ and Adrián Martínez-Moreno⁴, ¹Cardiology, Hospital Universitario, UANL, Monterrey, Mexico, ²Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, ³Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, ⁴Hospital Universitario, UANL, Monterrey, Mexico
Background/Purpose: Screening for cardiovascular (CV) disease in patients with rheumatoid arthritis (RA) remains controversial, however, there is agreement in considering echocardiography as the most immediate…
Abstract Number: 508 • 2018 ACR/ARHP Annual Meeting
Non-Invasive Evaluation of Left Atrial Pressure in Hispanic Patients with Rheumatoid Arthritis: A Case-Control Study
José R. Azpiri-López¹, Dionicio A. Galarza-Delgado², Iris J. Colunga-Pedraza³, Jose A. Davila-Jimenez⁴, Estefania E. Abundis-Marquez⁴, Andres H. Guillen-Lozoya⁴, Francisco J. Torres-Quintanilla⁴, Aldo Valdovinos-Bañuelos⁴, Ray Ramos-Cázares⁴, Raymundo Vera-Pineda⁴, Jesus A. Cardenas-de la Garza⁴, Rosa I. Arvizu-Rivera⁴ and Adrián Martínez-Moreno⁴, ¹Cardiology, Hospital Universitario, UANL, Monterrey, Mexico, ²Chief of Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, ³Rheumatology, Hospital Universitario, UANL, Monterrey, Mexico, ⁴Hospital Universitario, UANL, Monterrey, Mexico
Background/Purpose: In the last several years a higher prevalence of heart failure has been described in Rheumatoid arthritis (RA) patients, particularly heart failure with preserved…
Abstract Number: 804 • 2018 ACR/ARHP Annual Meeting
Prevalence of Echocardiographic Abnormalities in Patients with Systemic Sclerosis
Judit Lluch¹, Francisco Javier Narváez², Pablo Juárez¹ and Joan Miquel Nolla¹, ¹Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²Rheumatology Department, Hospital Universitario de Bellvitge, Idibell, Barcelona, Spain
Background/Purpose: To determine the prevalence of echocardiographic abnormalities and to identify associated clinical and laboratory features in a large systemic sclerosis (SSc) cohort. Methods: The…
Abstract Number: 1119 • 2017 ACR/ARHP Annual Meeting
Uncontrolled Gout Patients with Higher Heart Failure Hospitalization Rates in US
Robert Morlock¹, Pierre Chevalier², An-Chen Fu³ and Douglas C.A. Taylor³, ¹YourCareChoice, Ann Arbor, MI, ²IMS Health, Zaventem, Belgium, ³Ironwood Pharmaceuticals, Inc., Cambridge, MA
Background/Purpose: Gout is the most common form of inflammatory arthritis and is caused by elevated serum uric acid (sUA). Elevated sUA is associated with worsened…
Abstract Number: 1301 • 2017 ACR/ARHP Annual Meeting
Congenital Heart Defects in Children Born to Mothers with Rheumatic Disease and Anti-Ro and/or Anti-La Antibodies
Julie Couture¹, Linda T Hiraki², Franklin Silverio¹, Deepika Sharma¹ and Earl Silverman³, ¹Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ²Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, ³Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Transplacental passage of maternal anti-Ro IgG is thought to be critical in initiating inflammation leading to congenital heart block in neonatal lupus erythematosus (NLE).…
Abstract Number: 1486 • 2016 ACR/ARHP Annual Meeting
Associations Between Heart Rate Adjusted ST Segment and Heart Rate Variability in Patients with Rheumatoid Arthritis
Ahmad Osailan^1,2, Jet JJCS Veldhuijzen van Zanten^2,3, Joan Duda¹, Sally Fenton^1,2, Peter Rouse⁴, Nikos Ntoumanis⁵, George D. Kitas^1,2 and George Metsios^2,6, ¹School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, ²Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ³School of Sport, Exercise and Rehabilitation, University of Birmingham, Dudley, United Kingdom, ⁴Department for Health, University of Bath, Bath, United Kingdom, ⁵School of Psychology & Speech Pathology, Curtin University, Perth, Australia, ⁶Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for myocardial infarction (MI), which is often silent. Heart rate adjusted ST segment (ST/HR index)…
Abstract Number: 1494 • 2016 ACR/ARHP Annual Meeting
Myocardial Structure, Function, and Fibrosis in Patients with Rheumatoid Arthritis and Matched Control Subjects
Michelle J. Ormseth¹, William Bradham², Comfort Elumogo³, Srikanth Palanisamy⁴, Chia Liu⁵, Mark Lawson², Jonathan Soslow², Nadine Kawel⁶, David A. Bluemke⁷ and C Michael Stein², ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Vanderbilt University Medical Center, Nashville, TN, ³National Institutes of Health, Bethesada, MD, ⁴Cornell University, Ithaca, NY, ⁵National Institutes of Health, Bethsada, MD, ⁶National Institutes of Health, Bethsada, TN, ⁷National Institutes of Health, Bethesda, MD
Background/Purpose: The prevalence of heart failure is increased 2-fold in RA; this is not explained by ischemic heart disease or other risk factors for heart…
Abstract Number: 1727 • 2016 ACR/ARHP Annual Meeting
Association Between Biologic Therapies and Major Adverse Cardiac Events or Cardiac Heart Failure in Psoriatic Arthritis or Psoriasis: A Meta-Analysis
Benedicte Champs, Rheumatology, Medecine Toulouse Purpan Hospital, Lescure d'albigeois, France
Association between biologic therapies and major adverse cardiac events or cardiac heart failure in psoriatic arthritis or psoriasis: a meta-analysis. 1Champs B, 1Degboe Y, 1Ruyssen-Witrand…
Abstract Number: 1853 • 2016 ACR/ARHP Annual Meeting
Klf5+/-;Fli1+/- Mice Recapitulate Protracted Wound Healing and Cardiac and Intestinal Involvement Associated with Systemic Sclerosis
Kouki Nakamura¹, Yoshihide Asano², Takuya Miyagawa³, Megumi Hirabayashi³, Takashi Yamashita³, Ryosuke Saigusa¹, Shunsuke Miura², Tetsuo Toyama^3,4, Takehiro Takahashi¹, Yohei Ichimura¹, Takashi Taniguchi¹, Ayumi Yoshizaki³, Maria Trojanowska⁴ and Shinichi Sato¹, ¹Dermatology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan, ²University of Tokyo Graduate School of Medicine, Tokyo, Japan, ³Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, ⁴Arthritis Center, Boston University, Arthritis Center, Boston, MA
Background/Purpose: Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by vasculopathy and tissue fibrosis. Although the most recognizable manifestation is skin disease, SSc can…
Abstract Number: 1940 • 2016 ACR/ARHP Annual Meeting
High Prevalence of Inflammatory Heart Disease in Eosinophillic Granulomatosis with Polyangiitis (Churg Strauss) Patients
Eloi Garcia Vives¹, Len Harty² and David Jayne³, ¹Vall d'Hebrón Hospital, Barcelona, Spain, ²Vasculitis & Lupus, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom, ³Vasculitis and Lupus Clinic, Addenbrookes Hospital University of Cambridge, Cambridge, United Kingdom
Background/Purpose: To establish EGPA/Churg Strauss inflammatory heart disease prevalence and develop an algorithm for heart disease screening in EGPA patients. Methods: An audit of all…
Abstract Number: 1923 • 2015 ACR/ARHP Annual Meeting
The Role of Inflammatory Myeloid Cell Compartment in Myocardial Fibrogenesis and Remodelling in Systemic Sclerosis
Veronika Haunerdinger¹, Przemyslaw Blyszczuk², Elena Pachera¹, Rucsandra Dobrota³, Britta Maurer¹, Ulrich Grabmaier⁴, Karl Sotlar⁵, Oliver Distler¹ and Gabriela Kania¹, ¹Research of Systemic Autoimmune Diseases, Division of Rheumatology, University Hospital Zurich, 8952 Schlieren, Switzerland, ²Cardioimmunology, Center of Molecular Cardiology, University of Zurich, 8952 Schlieren, Switzerland, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Medical Clinic und Polyclinic I, Campus Großhadern, Maximilians University Munich, 81377 Munich, Germany, ⁵Institute of Pathology, Ludwig Maximilians University Munich, 81377 Munich, Germany
Background/Purpose: During the last years, there was a shift in systemic sclerosis (SSc)-related causes of death, indicating cardiac involvement and inflammatory dilated cardiomyopathy (iDCM) as…
Abstract Number: 2586 • 2015 ACR/ARHP Annual Meeting
Cardiac Magnetic Resonance Imaging Reveals Myocardial Damage in Patients with Active Rheumatoid Arthritis
Miia Holmström¹, Riitta Koivuniemi², Tarja Tiippana-Kinnunen², Antti Kuuliala³, Marjatta Leirisalo-Repo² and Sari Kivistö¹, ¹Radiology, HUS Medical Imaging Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ²Rheumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ³Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Background/Purpose: In rheumatoid arthritis (RA), cardiac involvement is common and frequently subclinical. We used cardiac MRI to identify myocardial abnormalities in patients with active RA,…

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