ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "Heart disease"

  • Abstract Number: 0345 • ACR Convergence 2022

    Association Between Cumulated Hydroxychloroquine in Systemic Lupus Erythematosus and Development of Cardiac Conduction Alterations: A Multiple Logistic Regression Analysis

    Alba Herrero-Morant1, Jon Zubiaur-Zamacola2, Adrián Margarida-De Castro2, Raquel Pérez-Barquín2, Miguel Ángel González-Gay3 and Ricardo Blanco4, 1Hospital Universitario Marqués de Valdecilla, Ontinyent, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 4Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Hydroxychloroquine (HCQ) is a widely used drug in Systemic Lupus Erythematosus (SLE). It may cause cardiac alterations which includes short term arrhythmic events (via…
  • Abstract Number: 1596 • ACR Convergence 2022

    The Role of Coronary Calcium Screening in Patients with Lupus Who Appear to Be at Low Cardiovascular Risk

    Sarah Stoots1, Joshua Baker1 and Joan Von Feldt2, 1University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Wilmington, DE

    Background/Purpose: Patients with Systemic Lupus Erythematosus (SLE) are at elevated cardiovascular risk. However, common risk calculators such as the atherosclerotic cardiovascular disease (ASCVD) risk estimator…
  • Abstract Number: 0679 • ACR Convergence 2022

    Outcomes of Antiphospholipid Antibody Syndrome and Acute Coronary Syndrome: Analysis of National Inpatient Sample 

    Faria Sami, Dennis Kumi and Shilpa Arora, John H. Stroger, Jr. Hospital of Cook County, Chicago, IL

    Background/Purpose: Antiphospholipid antibody syndrome (APLS) is strongly associated with the risk of cardiovascular events including acute coronary syndrome (ACS). However, there is limited data on…
  • Abstract Number: 1623 • ACR Convergence 2022

    Combined Single-Cell, Bulk RNA Sequencing and Proteomics Analysis Reveals New Candidate Targets Involved in Myocardial Fibrogenesis

    Ievgeniia Kocherova1, Elena Pachera2, Daria Nurzynska3, Franca Di Meglio3, Oliver Distler4, Przemysław Błyszczuk2 and Gabriela Kania2, 1Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Schlieren, Switzerland, 2Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 3Department of Public Health, University of Naples "Federico II", Naples, Italy, 4Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland

    Background/Purpose: Inflammatory dilated cardiomyopathy (iDCM) often leads to heart failure (HF), which is the main cause of cardiac mortality in patients with systemic autoimmune diseases.…
  • Abstract Number: 0741 • ACR Convergence 2022

    Prescribing Patterns of SGLT2 Inhibitors for Patients with Autoimmune Rheumatic Disease

    Emily G Oakes1, Jack Ellrodt1, May Choi2, Hongshu Guan1 and Karen Costenbader1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada

    Background/Purpose: Sodium-glucose co-transporter 2 inhibitors (SGLT2i, dapagliflozin, canagliflozin, and empagliflozin) are a class of oral hypoglycemic medication for management of Type II diabetes mellitus (T2D),…
  • Abstract Number: 1789 • ACR Convergence 2022

    Gout in Heart Failure Patients with Left Ventricular Assist Device Therapy in a Tertiary Academic Hospital

    Aakriti Arora1, Lakshmi Jayaram2, TEFERA ESHETU3 and FLORINA CONSTANTINESCU3, 1MedStar Washington Hospital Center, Georgetown University, Washington, DC, 2McGaw Medical Center, Northwestern University, Chicago, IL, 3MedStar Washington Hospital Center, Washington, DC

    Background/Purpose: Gout is one of the most common inflammatory joint diseases and is a disabling complication in patients with heart failure. Patients with gout and…
  • Abstract Number: 0805 • ACR Convergence 2022

    Rheumatic Fever and Streptococcal Cutaneous Infection: A Case-control Study in the Loyalty Islands, New Caledonia

    Quentin AMIC-DESVAUD1, Olivier MAILLARD2, Sylvia IACOBELLI3, Thomas BARDIN4 and Yves-Marie DUCROT5, 1Province des îles Loyauté, Lifou, New Caledonia, 2Centre Hospitalier Universitaire de la Reunion, Saint-Denis, France, 3Centre Hospitalier Universitaire, Saint Dénis de la Réunion, France, 4Université de Paris, Paris, France, 5Province des îles Loyauté, We, Lifou Island, New Caledonia

    Background/Purpose: Acute Rheumatic Fever (ARF) and Rheumatic Heart Disease (RHD) remain major public health problems in the South Pacific. Triggering by group A beta hemolytic…
  • Abstract Number: 1815 • ACR Convergence 2022

    Consistent Colchicine Use Is Associated with Decreased Major Adverse Cardiovascular Events in Patients with Gout and Established Cardiovascular Disease

    Gary Ho1, Michael Toprover2, Daria Crittenden3, binita Shah4 and Michael Pillinger5, 1New York University Grossman School of Medicine, VA New York Harbor Health Care System, Brooklyn, NY, 2Division of Rheumatology, New York University Grossman School of Medicine and Rheumatology Section, New York Harbor Health Care System, New York Campus of the U.S. Department of Veterans Affairs, New York, NY, 3CymaBay Therapeutics, New York University Grossman School of Medicine, Newark, CA, 4New York University Grossman School of Medicine, VA New York Harbor Health Care System, New York, NY, 5NYU Grossman School of Medicine, New York, NY

    Background/Purpose: Patients with gout are more likely than those without to have traditional risk factors for cardiovascular (CV) disease. Furthermore, the chronic, low-level inflammation experienced…
  • Abstract Number: 0896 • ACR Convergence 2022

    Screening of Lipids in Patients with Rheumatoid Arthritis: Academic Rheumatology Practice Quality Improvement Analysis

    Sukhraj Singh1 and Gurjit S. Kaeley2, 1University of Florida-Jacksonville, Jacksonville, FL, 2UF COM-J, Ponte Vedra Beach, FL

    Background/Purpose: Patients with Rheumatoid Arthritis (RA) have 50% increased risk of cardiovascular disease (CVD) mortality compared with the general population. The American College of Cardiology/American…
  • Abstract Number: 1871 • ACR Convergence 2022

    Hospitalization Outcomes for Acute Myocardial Infraction and Acute Heart Failure in Patients with Idiopathic Inflammatory Myopathies (IIM) from 2016-2019 National Inpatient Sample (NIS)

    Zi Ying Li1, Siyi Huang2, Kevin Xi3, Deepan Dalal4 and Anthony Reginato5, 1Roger Williams Medical Center, Providence, RI, 2UCSF Fresno, Fresno, CA, 3Brown University, Providence, 4Brown University School of Medicine, Providence, RI, 5Brown University, Providence, RI

    Background/Purpose: Cardiovascular disease was encountered in 15% of hospital admission from 2016-2017 for patients with idiopathic inflammatory myopathies (IIM) based on the National Inpatient Sample…
  • Abstract Number: 0898 • ACR Convergence 2022

    Risk of Aortic Stenosis and Undergoing Aortic Valve Replacement in Rheumatoid Arthritis: An Underrecognized Cardiovascular Complication

    Tate Johnson1, Yangyuna Yang2, Chetaj Mahabir2, Andrew Goldsweig2, Punyasha Roul3, Joshua Baker4, Brian Sauer5, Grant Cannon6, Ted Mikuls7 and Bryant England2, 1University of Nebraska Medical Center, Elkhorn, NE, 2University of Nebraska Medical Center, Omaha, NE, 3UNMC, Omaha, NE, 4University of Pennsylvania, Philadelphia, PA, 5Salt Lake City VA/University of Utah, Salt Lake City, UT, 6Retired, Salt Lake City, UT, 7Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Valvular carditis is reported as a rare extra-articular manifestation of rheumatoid arthritis (RA). In animal models with coexistent inflammatory arthritis, pro-inflammatory infiltrates of T…
  • Abstract Number: 1963 • ACR Convergence 2022

    Lipid Screening and Statin Use in Rheumatoid Arthritis Patients in an Underserved Population

    Colleen O'Neill1 and Veena Patel2, 1Dell Medical School - UTHealth Austin, Austin, TX, 2Dell Medical School - UT Health Austin, Austin, TX

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of atherosclerotic cardiovascular disease (ASCVD) compared to the general population and RA is considered a…
  • Abstract Number: 0981 • ACR Convergence 2022

    QTc Prolongation in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Treated with Hydroxychloroquine – Preliminary Results from a Single Center Study

    Tanmayee Bichile1, Susan Manzi2 and Tarun Sharma3, 1Allegheny Health Network, Gibsonia, PA, 2Allegheny Health Network, Lupus Center of Excellence, Wexford, PA, 3Allegheny Health Network, Pittsburgh, PA

    Background/Purpose: The effect of hydroxychloroquine (HCQ) on QTc interval in patients with rheumatic diseases is under scrutiny since the COVID-19 pandemic, however studies have shown…
  • Abstract Number: 2169 • ACR Convergence 2022

    Cardiac Rhythm and Conduction Abnormalities in Systemic Sclerosis-meta-analysis

    Drashti Antala1, Angkawipa Trongtorsak1, Qingqing Meng1, Akshaya Ramachandran1, Aanshi Patel2, Pabitra Adhikari1, Prasun Pudasainee1 and Krutarth Pandya3, 1Ascension Saint Francis hospital, Evanston, IL, 2B.J. Medical College, Ahmedabad, Ahmedabad, India, 3Trumbull Regional Medical Centre, Warren, OH

    Background/Purpose: Systemic sclerosis( SSc) can primarily cause repeated focal ischaemic insults in the myocardium and result in irreversible myocardial fibrosis. Myocardial involvement, when becomes clinically…
  • Abstract Number: 0983 • ACR Convergence 2022

    Hydroxychloroquine Use and Heart Failure with Preserved Ejection Fraction in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis

    Jake Altier, Fedelis Mutiso, Paul Nietert, Sheldon Litwin and Jim Oates, Medical University of South Carolina, Charleston, SC

    Background/Purpose: Initially used as an antimalarial, hydroxychloroquine (HCQ) is standard of care treatment for systemic lupus erythematosus (SLE) and is used as monotherapy or adjunct…
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