Abstracts tagged "Heart disease"

Abstract Number: 1500 • ACR Convergence 2020
Electrocardiographic QT Intervals in Infants Exposed to Hydroxychloroquine Throughout Gestation
Deborah Friedman¹, Mimi Kim², Nathalie Costedoat-Chalumeau³, Robert Clancy⁴, Joshua Copel⁵, Colin Phoon⁶, Bettina Cuneo⁷, Rebecca Cohen⁶, Mala Masson⁶, Benjamin Wainwright⁶, Noel Zahr⁸, Amit Saxena⁴, Peter Izmirly⁹ and Jill Buyon¹⁰, ¹New York Medical College, Valhalla, ²Albert Einstein College of Medicine, Bronx, ³APHP, Université de Paris, Paris, France, ⁴NYU School of Medicine, New York, ⁵Yale School of Medicine, New Haven, ⁶New York University School of Medicine, New York, ⁷University of Colorado School of Medicine, Aurora, ⁸Pitié-Salpêtrière University Hospital, Paris, France, ⁹Department of Medicine, New York University School of Medicine, New York, NY, ¹⁰Department of Medicine, NYU School of Medicine, New York, NY
Background/Purpose: Based on inhibition of viral replication and limited reports on clinical efficacy, hydroxychloroquine (HCQ) was initially considered as a prophylaxis and treatment of COVID-19. …
Abstract Number: 1667 • ACR Convergence 2020
Development of Autoimmune Diseases and HLA Associations in Children with Neonatal Lupus and Their Unaffected Siblings
Amit Saxena¹, Aaron Garza Romero², Daniel Gratch³, Peter Izmirly⁴, Hannah Ainsworth⁵, Miranda Marion⁵, Carl Langefeld⁶, Robert Clancy⁷ and Jill Buyon⁸, ¹NYU School of Medicine, New York, ²Gonzaba Medical Group, San Antonio, ³NYU Langone Health, New York, ⁴Department of Medicine, New York University School of Medicine, New York, NY, ⁵Wake Forest School of Medicine, Winston-Salem, ⁶Wake Forest School of Medicine, Winston Salem, NC, ⁷New York University School of Medicine, New York, NY, ⁸Department of Medicine, NYU School of Medicine, New York, NY
Background/Purpose: Neonatal Lupus (NL) is a model of passively acquired autoimmunity conferred by exposure to maternal anti-Ro antibodies with major manifestations being congenital heart block…
Abstract Number: 1687 • ACR Convergence 2020
Kawasaki Disease Shock Syndrome in the Intensive Care Unit: A Single Center Cohort
Monica Bray¹, Jennifer Rammel², Andrea Ramirez¹, Kristen Sexson¹, Fong Lam¹, Eyal Muscal³ and Marietta DeGuzman³, ¹Baylor College of Medicine, Houston, TX, ²University of Florida Health Jacksonville, Jacksonville, FL, ³Baylor College of Medicine, Houston
Background/Purpose: Kawasaki disease (KD), a well described vasculitis of childhood, is the leading cause of acquired heart disease in developed countries. Kawasaki disease shock syndrome…
Abstract Number: 0433 • ACR Convergence 2020
Racial Disparities and New SLE-Specific Predictors of Stroke and Ischemic Heart Disease in Patients with Lupus
Shivani Garg¹, Christie Bartels², Gaobin Bao³, Cristina Drenkard⁴ and S. Sam Lim³, ¹UW Madison, Madison, WI, ²University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI, ³Emory University, Atlanta, GA, ⁴Division of Rheumatology, Department of Medicine, Emory School of Medicine, Atlanta, GA
Background/Purpose: In the US, cardiovascular disease (CVD) is the leading cause of disparities in life expectancy between black and white populations. We recently reported a…
Abstract Number: 0562 • ACR Convergence 2020
The Relationship Between Heart Disease Risk Profile and Osteoarthritis, Overall and by Multi-/Single-Joint Involvement
Anthony Perruccio¹, Shatabdy Zahid², Calvin Yip³, J Denise Power², Mayilee Canizares², George Heckman⁴ and Elizabeth Badley¹, ¹Krembil Research Institute, UHN; University of Toronto, Toronto, ON, Canada, ²Krembil Research Institute, University Health Network, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴University of Waterloo, Waterloo, ON, Canada
Background/Purpose: Osteoarthritis (OA) and heart disease (HD) are among the most common chronic conditions. Several studies have shown that OA increases the risk of HD…
Abstract Number: 0657 • ACR Convergence 2020
Gout and Heart Failure in the US
Gurkipal Singh¹, Maanek Sehgal² and Alka Mithal³, ¹Stanford University, Stanford, CA, ²UCLA, Los Angeles, CA, ³ICORE, Woodside, CA
Background/Purpose: Heart failure (HF) is the eighth leading cause of death in the US, with a 38% increase in the number of deaths due to…
Abstract Number: 0664 • ACR Convergence 2020
Uric Acid Level Is Associated with Severity of Heart Failure with Preserved Ejection Fraction
Ana B. Arevalo¹, Alba Munoz², Faris Haddadin², Karan Sud², Gustavo Contreras², Shane Murray², Yousaf Ali² and Edgar Argulian², ¹Mount Sinai St. Luke's-West/ Icahn School of Medicine, New York, NY, ²Mount Sinai St. Luke's-West/ Icahn School of Medicine, New York
Background/Purpose: Hyperuricemia (HUC) has been shown to have an impact in the left atrium and left ventricle remodeling leading to the development of heart failure…
Abstract Number: 1183 • ACR Convergence 2020
Factors Associated with Incident Heart Failure Subtypes in Patients with Rheumatoid Arthritis Using Electronic Health Record Data
Sicong Huang¹, Tianrun Cai¹, Brittany Weber¹, Zeling He¹, Kumar Dahal¹, Chuan Hong², Andrew Cagan³, Jacob Joseph⁴, Seoyoung Kim¹, Daniel H Solomon¹, Tianxi Cai² and Katherine Liao¹, ¹Brigham and Women's Hospital, Boston, MA, ²Harvard Medical School; Harvard T.H. Chan School of Public Health, Boston, MA, ³Partners Healthcare, Somerville, MA, ⁴Brigham and Women's Hospital; Veterans Affairs Boston Healthcare System, Boston, MA
Background/Purpose: Heart failure (HF) is a major cause of mortality in rheumatoid arthritis (RA) and is broadly categorized into two subtypes, each with distinct pathophysiology:…
Abstract Number: 1184 • ACR Convergence 2020
In a Prospective RA Cohort, Higher Baseline Disease Activity Is an Independent Predictor of Decline in Left Ventricular Diastolic Function
Elizabeth Park¹, Kazato Ito², Christopher Depender¹, Jon Giles¹ and Joan Bathon¹, ¹Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, ²Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY
Background/Purpose: Rheumatoid Arthritis (RA) patients are at nearly 50% increased risk of heart failure (HF) compared to non-RA patients, despite adjusting for the presence of…
Abstract Number: 1187 • ACR Convergence 2020
Red Cell Distribution Width Is Associated with ASCVD Risk Score and CVD in RA After Initiation of Methotrexate
Ibtissam Gad¹, Sofi Damjanovska², Lenche Kostadinova³, Alyssa Lange⁴, Christopher Burant⁴, Brigid Wilson⁵, Taissa Bej⁵, Nora Singer⁶, Maya Mattar⁷, David Zidar⁸ and Donald Anthony⁹, ¹Case Western Reserve/ Cleveland VA Medical Center, Cleveland Heights, OH, ²Case Western Reserve University/Cleveland VA Medical Center, Cleveland Heights, OH, ³(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Highland Heights, OH, ⁴Case Western Reserve University, Cleveland, ⁵Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, ⁶The MetroHealth System, Case Western Reserve University School of Medicine, Cleveland, OH, ⁷Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, ⁸Case Western Reserve University/Cleveland VA Medical Center, Cleveland, ⁹Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH
Background/Purpose: Rheumatoid arthritis (RA) has been shown to be associated with increased risk of cardiovascular disease (CVD) and mortality. Red cell distribution width (RDW) represents…
Abstract Number: 377 • 2019 ACR/ARP Annual Meeting
Novel Approach to the Treatment of Cardiac Sarcoidosis with TNF-alpha Inhibition
Matthew Baker¹, Khushboo Sheth ¹, Julia Simard ², Stanford Shoor ¹ and Mark Genovese ³, ¹Stanford University, Palo Alto, CA, ²Stanford University School of Medicine, Palo Alto, CA, ³Stanford University, Stanford, CA
Background/Purpose: Sarcoidosis is a systemic inflammatory disease characterized by the presence of noncaseating granulomas. When it affects the myocardium, it can result in electrical conduction…
Abstract Number: 587 • 2019 ACR/ARP Annual Meeting
Increased Prevalence of Cardiac Disorders in Dutch Ankylosing Spondylitis Patients: The CARDAS Study
Milad Baniaamam¹, Sjoerd Heslinga ², Thelma Konings ³, Otto Kamp ³, Vokko van Halm ³, Irene van der Horst-Bruinsma ² and Mike Nurmohamed ⁴, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Reade, Amsterdam|Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ³Amsterdam University Medical Center, location VUmc, Department of Cardiology, Amsterdam, Amsterdam, Netherlands, ⁴Amsterdam Rheumatology and immunology Center location Reade and Amsterdam UMC location VU medical center, Amsterdam, Netherlands
Background/Purpose: The overall mortality rate in ankylosing spondylitis (AS) patients is increased by 60–90% compared with the general population. This higher mortality rate is predominately…
Abstract Number: 1564 • 2019 ACR/ARP Annual Meeting
Renal Arteriosclerosis Predicts Cardiovascular Disease in Lupus Nephritis
Shivani Garg¹, Sarah Panzer ², Karen Hansen ³, Callie Plafkin ⁴, Maureen Smith ² and Christie Bartels ¹, ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²UW-Madison, Madison, ³UW Madison, Madison, ⁴UW Health, Madison
Background/Purpose: Patients with lupus nephritis (LN) have a 9-fold higher risk of cardiovascular disease (CVD), highlighting the urgent need to target CVD prevention. Studies in…
Abstract Number: 2330 • 2019 ACR/ARP Annual Meeting
Factors Associated with Differing Types of Heart Failure in Patients with Rheumatoid Arthritis
Sicong Huang¹, Tianrun Cai ², Daniel Solomon ³, Zeling He ¹, Kumar Dahal ², Chuan Hong ⁴, Andrew Cagan ⁵, Seoyoung C. Kim ⁶, Jacob Joseph ⁷, Tianxi Cai ⁸ and Katherine Liao ², ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, ³Brigham and Women´s Hospital, Div. of Rheumatology, Immunology and Allergy, Boston, MA, ⁴Harvard Medical School, Boston, MA, ⁵Research Information Science and Computing, Partners Healthcare, Boston, ⁶Brigham and Women’s Hospital and Harvard Medical School, Boston, ⁷Veterans Affairs Boston Healthcare System and Brigham and Women’s Hospital, Boston, MA, ⁸Harvard T.H. Chan School of Public Health, Boston
Background/Purpose: For patients with rheumatoid arthritis (RA), heart failure (HF) is a significant cause of morbidity and mortality. HF is further classified into 2 subtypes…
Abstract Number: 1527 • 2018 ACR/ARHP Annual Meeting
Tofacitinib Improves Left Ventricular Mass and Cardiac Output in Rheumatoid Arthritis Patients with Chronic Heart Failure
Kensuke Kume¹, Kanzo Amano², Susumu Yamada³, Toshikatsu Kanazawa³ and Kazuhiko Hatta⁴, ¹Rheumatology, Hiroshima Clinic, Hiroshima, Japan, ²rheumatology., hiroshima clinic, Hiroshima, Japan, ³rheumatology, hiroshima clinic, hiroshima, Japan, ⁴Rheumatology, Hatta Clinic, Kure, Japan
Background/Purpose: Rheumatologists need to develop primary and secondary prevention strategies for cardiovascular disease (CVD) in rheumatoid arthritis (RA) patients. We reported tofacitinib (Tofa) (with or…

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