Abstracts tagged "Heart disease"

Abstract Number: 1886 • 2015 ACR/ARHP Annual Meeting
Myocardial Fibrosis Detected By Magnetic Resonance Imaging Is a Predictor of Heart Failure in Systemic Sclerosis (SSc) Patients
Tatiana Sofia Rodriguez-Reyna¹, Martha Morelos-Guzmán², Pamela Mercado Velazquez³, Pablo Henrandez-Reyes⁴, Karla Montero-Duarte⁵, Cynthia Martinez-Reyes⁶, Carlos Reyes-Utrera⁶ and Carlos Nunez Alvarez³, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Radiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ³Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico, ⁴Department of Cardiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁵Department of Imaging and Radiology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico, ⁶Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
Background/Purpose: In previous studies we showed that prevalence of myocardial fibrosis in SSc patients is 45% and is associated to diffuse disease (dcSSc) and lower…
Abstract Number: 1923 • 2015 ACR/ARHP Annual Meeting
The Role of Inflammatory Myeloid Cell Compartment in Myocardial Fibrogenesis and Remodelling in Systemic Sclerosis
Veronika Haunerdinger¹, Przemyslaw Blyszczuk², Elena Pachera¹, Rucsandra Dobrota³, Britta Maurer¹, Ulrich Grabmaier⁴, Karl Sotlar⁵, Oliver Distler¹ and Gabriela Kania¹, ¹Research of Systemic Autoimmune Diseases, Division of Rheumatology, University Hospital Zurich, 8952 Schlieren, Switzerland, ²Cardioimmunology, Center of Molecular Cardiology, University of Zurich, 8952 Schlieren, Switzerland, ³Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁴Medical Clinic und Polyclinic I, Campus Großhadern, Maximilians University Munich, 81377 Munich, Germany, ⁵Institute of Pathology, Ludwig Maximilians University Munich, 81377 Munich, Germany
Background/Purpose: During the last years, there was a shift in systemic sclerosis (SSc)-related causes of death, indicating cardiac involvement and inflammatory dilated cardiomyopathy (iDCM) as…
Abstract Number: 2586 • 2015 ACR/ARHP Annual Meeting
Cardiac Magnetic Resonance Imaging Reveals Myocardial Damage in Patients with Active Rheumatoid Arthritis
Miia Holmström¹, Riitta Koivuniemi², Tarja Tiippana-Kinnunen², Antti Kuuliala³, Marjatta Leirisalo-Repo² and Sari Kivistö¹, ¹Radiology, HUS Medical Imaging Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ²Rheumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland, ³Bacteriology and Immunology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Background/Purpose: In rheumatoid arthritis (RA), cardiac involvement is common and frequently subclinical. We used cardiac MRI to identify myocardial abnormalities in patients with active RA,…
Abstract Number: 2964 • 2015 ACR/ARHP Annual Meeting
Influences of Various Factors on Survival of Patients Treated with Pulmonary Arterial Hypertension-Specific Drugs Combination Therapy in Patients with Connective Tissue Diseases
Sumiaki Tanaka¹, Yu Matsueda², Eisuke Ogawa¹, Jun Okada³ and Shunsei Hirohata¹, ¹Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, ²Rheumatology and Infectious diseases, Kitasato University School of Medicine, Kanagawa, Japan, ³Rheumatology, Kitasato University Hospital, Sagamihara, Japan
Background/Purpose: In patients with connective tissue disease (CTD), especially systemic sclerosis (SSc), several mechanisms have been implicated for the development of pulmonary hypertension (PH), including…
Abstract Number: 2991 • 2015 ACR/ARHP Annual Meeting
Evaluation of Serum Levels of Adipokines and Interleukines in Pericardial Effusion Related to Systemic Sclerosis
Angela Chialà¹, Cinzia Rotondo¹, Maria Grazia Anelli¹, Emanuela Praino¹, Luca Cantarini², Crescenzio Scioscia¹, Margherita Giannini¹, Giovanni Lapadula¹ and Florenzo Iannone¹, ¹DIM, Rheumatology Unit, Bari, Italy, ²Univ Siena, Siena, Italy
Background/Purpose: Pericardial involvement is common in rheumatic disease, as rheumatoid arthritis, lupus erythematosus, mixed connective disease and systemic sclerosis. Few data are available about pathogenesis…
Abstract Number: 2905 • 2014 ACR/ARHP Annual Meeting
The IL-6/Th17 Axis Promotes Autoantibody-Associated Autoimmune Valvular Carditis in Mice
Jennifer L. Auger¹, Brianna J. Engelson², Yaya Wang³, Erik J. Peterson⁴ and Bryce A. Binstadt⁵, ¹Center for Immunology and Department of Pediatrics, University of Minnesota, Minneapolis, MN, ²Pediatrics, University of Minnesota, Minneapolis, MN, ³Medicine, University of Minnesota, Minneapolis, MN, ⁴University of Minnesota, Minneapolis, MN, ⁵Pediatric Rheumatology, University of Minnesota, Minneapolis, MN
Background/Purpose: Autoimmune valvular carditis occurs in patients with systemic lupus erythematosus, rheumatoid arthritis and rheumatic fever, but the pathogenic mechanisms remain incompletely defined. Spontaneous autoimmune…
Abstract Number: 1909 • 2014 ACR/ARHP Annual Meeting
Incidence of Congestive Heart Failure in Subjects with Rheumatoid Arthritis Receiving Anti-Tumour Necrosis Factor Drugs: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis
Alper van Sijl¹, Mamas Mamas², Mark Lunt^3,4, . BSRBR Control Centre Consortium³, Kath Watson⁵, Deborah P. Symmons^3,6 and Kimme L. Hyrich⁷, ¹Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ²Manchester Heart Centre, Manchester Royal Infirmary, Oxford Road, Manchester, UK; Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom, ⁵Arthritis Research UK Epidemiology Unit, Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, ⁶Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ⁷Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom
Background/Purpose Subjects with rheumatoid arthritis (RA) are at a higher risk of developing cardiovascular (CV) disease compared to the general population, with an increased incidence…
Abstract Number: 1681 • 2014 ACR/ARHP Annual Meeting
Heart Transplantation in 6 Patients with Systemic Sclerosis and a Primary Cardiac Involvement
Alena Ikic¹, Emmanuel Chatelus², Eric Epailly³, Hélène Kremer³, Jean Sibilia², Jacques Gottenberg⁴, Sabine Pattier⁵, Erwan Flecher⁶, Céline Goeminne⁷ and Thierry Martin¹, ¹Strasbourg University Hospital, Strasbourg, France, ²Division of Rheumatology, University Hospital of Strasbourg, Strasbourg, France, ³Cardiology, Strasbourg University Hospital, Strasbourg, France, ⁴Rheumatology, Strasbourg University Hospital, Strasbourg, France, ⁵Cardiology, Nantes University Hospital, Nantes, France, ⁶Cardiac Surgey, Rennes University Hospital, Rennes, France, ⁷Cardiology, Lille University Hospital, Lille, France
Background/Purpose: There is no specific treatment for primary cardiac involvement in SSc. Even if heart transplantation is an option, only 1 case have been reported1.…
Abstract Number: 1253 • 2014 ACR/ARHP Annual Meeting
Anakinra – a Promising New Therapy for Idiopathic Recurrent Pericarditis
Sonia Jain¹, Charat Thongprayoon², Raul Espinosa¹, Sharonne Hayes¹, Kyle Klarich¹, Kevin Moder³, Nandan Anavekar¹, Jae Oh¹ and Eric L. Matteson⁴, ¹Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ²Department of Medicine, Mayo clinic, Rochester, MN, ³Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose Idiopathic recurrent pericarditis (IRP) is a debilitating condition that can be recalcitrant to conventional therapy. Some patients develop steroid dependency with the attendant risks…
Abstract Number: 738 • 2014 ACR/ARHP Annual Meeting
Troponin T as a Diagnostic and Prognostic Biomarker of Primary Cardiac Involvement in Systemic Sclerosis
Silvia Laura Bosello, Giacomo De Luca, Federico Parisi, Giorgia Berardi, Manuela Rucco, Giovanni Canestrari and Gianfranco Ferraccioli, Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose .Heart involvement is common in Systemic Sclerosis (SSc), even if often clinically silent, and represents one of the leading cause of death in these…
Abstract Number: 2830 • 2013 ACR/ARHP Annual Meeting
First Stage Of a Simon’s Two-Stage Optimal Approach Supports Placental Transfer Of Hydroxychloroquine and a Reduced Recurrence Rate Of The Cardiac Manifestations Of Neonatal Lupus
Peter M. Izmirly¹, Nathalie Costedoat-Chalumeau², Amit Saxena³, Amanda Zink⁴, Zoey Smith³, Deborah Friedman⁵ and Jill P. Buyon¹, ¹Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Internal Medicine, Hopital Cochin, Paris, France, ³Rheumatology, New York University School of Medicine, New York, NY, ⁴NYU Hospital for Joint Diseases, New York University School of Medicine, New York, NY, ⁵Division of Pediatric Cardiology, New York Medical College, Valhalla, NY
Background/Purpose: A previous case control study suggested that hydroxychloroquine (HCQ) might prevent the development of cardiac Neonatal Lupus (cardiac NL) in anti-SSA/Ro antibody (ab) exposed…
Abstract Number: 2834 • 2013 ACR/ARHP Annual Meeting
Maternal data Analysis Of The French Registry Of 205 Cases Of Immune Congenital Heart Block (neonatal lupus)
Kateri Levesque¹, Nathalie Morel², Gaëlle Guettrot-Imbert³, Mohamed Hamidou⁴, Jean Loup Pennaforte⁵, Pauline Orquevaux⁵, Jean-Charles Piette⁶, Christophe Deligny⁷, Zahir Amoura⁸, Olivier Meyer⁹, Olivier Fain¹⁰, Agathe Masseau¹¹, Holly Bezanahary¹², Pascal Cathebras¹³, Elizabeth Diot¹⁴, Yves Dulac¹⁵, Loic Guillevin¹⁶, Eric Hachulla¹⁷, Jean-Louis Pasquali¹⁸, Anne Besancon-Bergelin¹⁹, Bernard Bonnotte²⁰, Jérome Lebidois²¹, Alice Maltret²², Elisabeth Villain²² and Nathalie Costedoat-Chalumeau²³, ¹Medicine Interne, Hopital Cochin, Paris, France, ²Internal Medicine, COCHIN, Paris, France, ³Internal Medicine, Centre Hospitalier de Clermont-Ferrand, Clermont-Ferrand, France, ⁴CHU Hôtel Dieu, Nantes, Nantes, France, ⁵Hu Robert Debre, CHU Reims, Reims, France, ⁶Department of Internal Medicine 1., CHU Pitié-Salpêtrière, Paris, France, ⁷Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, ⁸Department of Internal Medicine 2. Referal center for SLE/APS, CHU Pitié-Salpêtrière, Paris, France, ⁹Rheumatology, Bichat University Hospital, Paris, France, ¹⁰Internal Medicine, Jean Verdier Hospital, Bondy, France, ¹¹Internal Medicine Department, Nantes University Hospital, Nantes, France, ¹²Internal Medicine, University Hospital of Limoges, Limoges, France, ¹³Internal Medicine, University Hospital St Etienne, St Etienne, France, ¹⁴Department of Internal Medicine, Hôpital Bretonneau, Centre Hospitalier Régional Universitaire de Tours, Tours, France, Tours, France, ¹⁵University Hospital Toulouse, Paris, France, ¹⁶Internal Medicine, Hôpital Cochin, University Paris Descartes, Paris, France, ¹⁷Internal Medicine, University Hospital Lilles, Lille CEDEX, France, ¹⁸Strasbourg University, Hospital, CNRS UPR 3572, Strasbourg, France, ¹⁹Internal Medicine, Le Mans Hospital, Le Mans, France, ²⁰Department of Internal Medicine, Centre Hospitalier de Dijon, Dijon, France, ²¹Cardiac Institute, Paris, France, ²²Cardiology, Groupe Hospitalier Necker - Enfants Malades, Paris, France, ²³Internal Medicine, Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France
Background/Purpose: Congenital heart block (CHB) occurs in 1 to 2 % of pregnancies exposed to anti-SSA antibodies. Few data are available regarding the risk of…
Abstract Number: 2589 • 2013 ACR/ARHP Annual Meeting
Scleroderma Patients With Pulmonary Hypertension and Increased Pulmonary Capillary Wedge Pressure In The Pulmonary Hypertension Assessment and Recognition Of Outcomes In Scleroderma (PHAROS) Cohort
Matthew R. Lammi^1,2, Lesley Ann Saketkoo^3,4, Jessica K. Gordon⁵, Paula Lauto⁶ and Virginia D. Steen⁷, ¹Section of Pulmonary and Critical Care Medicine, LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ²Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, ³Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, ⁴LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, ⁵Rheumatology, Hospital for Special Surgery, New York, NY, ⁶Pulmonary and Critical Care Medicine, LSU Health Sciences Center, New Orleans, LA, ⁷Department of Rheumatology, Georgetown University Medical Center, Washington, DC
Background/Purpose: Systemic sclerosis (SSc) commonly leads to pulmonary hypertension (PH), which may be associated with left heart disease and an elevated pulmonary capillary wedge pressure…
Abstract Number: 2038 • 2013 ACR/ARHP Annual Meeting
Congenital Heart Block Related With Maternal Autoimmune Diseases: Descriptive Analysis Of a Series Of 17 Cases
Pamela Inés Doti¹, Ona Escoda², Sergi Cesar-Diaz³, Narcís Masoller⁴, Irene Teixidó⁴, Josep Maria Martinez⁴, Georgia Sarquella-Brugada⁵ and Gerard Espinosa², ¹Department of Autoimmune Diseases, Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, ²Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, ³Arrhythmia Unit, Cardiology Section, Arrhythmia Unit, Cardiology Section, Hospital Sant Joan de Déu, Barcelona, Barcelona, Spain, ⁴Maternal Fetal Medicine Department, Hospital Clínic, Bacelona, Barcelona, Spain, ⁵Arrhythmia Unit, Cardiology Section, Hospital Sant Joan de Déu, Barcelona, Barcelona, Spain
Background/Purpose: To describe the clinical characteristics of maternal autoimmune-mediated fetal congenital heart block (CHB) in a cohort of pregnant women from an Autoimmune Diseases Pregnancy…
Abstract Number: 1277 • 2013 ACR/ARHP Annual Meeting
A Pilot Study Of Young Adults With Juvenile Dermatomyositis With Decreased Nailfold Capillary End Row Loops: Brachial Artery Reactivity and Oxidized Lipids
Lauren M. Pachman^1,2, Maureen A. McMahon³, Tamar Polonsky⁴, Gabrielle A. Morgan¹, Maria Amoruso⁵ and Chiang-Ching Huang⁶, ¹Cure JM Myositis Center, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, IL, ²Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁴Cardiology, University of Chicago Medicine, Chicago, IL, ⁵Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Cure JM Myositis Center, Chicago, IL, ⁶Zilber School of Public Health, University of Wisconsin at Milwaukee, Milwaukee, WI
Background/Purpose: Our center previously reported increased carotid intima media thickness, and lower high-density lipoprotein (HDL) levels in young or middle-age adults with a history of…

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