ACR Meeting Abstracts

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Abstracts tagged "Heart disease"

  • Abstract Number: 0641 • ACR Convergence 2024

    Predictive Validity of Coronary Artery Calcium Scoring in Low Risk Systemic Lupus Erythematous Patients

    Katherine Chakrabarti1, Apurba Chakrabarti2, Emily Lewis2 and William McCune3, 1University of Michigan, Ann Arbor, MI, 2University of Michigan Hospital, Ann Arbor, MI, 3U Michigan, Ann Arbor, MI

    Background/Purpose: Traditionally, a coronary artery calcium (CAC) score of zero is associated with low rates (0.1-0.2% annualized risk) of major adverse cardiovascular outcomes (MACE). While…
  • Abstract Number: 2227 • ACR Convergence 2024

    Worrisome Mortality Trends over 20 Years Among Patients with Underlying Ischemic Heart Disease and Rheumatoid Arthritis

    Yukthi Mudiam1 and Shreyas Singireddy2, 1Apollo Institute of Medical Sciences and Research, Richmond, TX, 2Department of Cardiology, University of Illinois College of Medicine, Peoria, IL

    Background/Purpose: Ischemic heart disease (IHD) is one of the leading causes of death in the United States. Rheumatoid arthritis (RA), a chronic inflammatory condition affecting…
  • Abstract Number: 0675 • ACR Convergence 2024

    Hydroxychloroquine Induced Cardiomyopathy: A Biopsy Proven Case Series

    Swetapadma Tripathy1, Davina Chen2, Lanny DiFranza3 and Bibi Ayesha4, 1Montefiore Medical Center, Forest Hills, NY, 2Montefiore Medical Center, New Rochelle, NY, 3Montefiore Medical Center, New York City, NY, 4Montefiore Medical Center, Metuchen, NJ

    Background/Purpose: Cardiomyopathy is a rare, life-threatening adverse effect of hydroxychloroquine (HCQ) use. There is a paucity in literature regarding treatment and prognosis in these cases. The aim…
  • Abstract Number: 2429 • ACR Convergence 2024

    Impact of Hydroxychloroquine Level on ECG QTC Interval in Patients with Rheumatic Systemic Autoimmune Diseases: A Real-life Study

    Carmen Raya-Santos1, José Rosas-Gómez de Salazar2, Mariana Marco3, Ana Pons-Bas3, Rocío Gallego Campuzano4, Juan Carlos Cortes4, Lara Pons-Canet3, Maruan Shalabi3, José Miguel Senabre3, José Antonio Bernal5, Gregorio Santos-Soler6, Xavier Barber7 and Jose Alberto Garcia Gomez7, 1Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 2Hospital Marina Baixa, PALMA DE MALLORCA, Comunidad Valenciana, Spain, 3Hospital Marina Baixa, Villajoyosa, Spain, 4Hospital Marina Baixa, Villajoyosa, Comunidad Valenciana, Spain, 5Hospital Marina Baixa (Villajoyosa), Alicante, Spain, 6Hospital Marina Baixa, Villajoyosa, 7Miguel Hernandez University, Villajoyosa, Spain

    Background/Purpose: The administration of hydroxychloroquine-sulphate (HCQ) can lead to the risk of QTc prolongation and cardiac arrhythmias. We evaluated the HCQ concentration and the incidence…
  • Abstract Number: 0683 • ACR Convergence 2024

    Prognostic Value of Systemic Sclerosis-associated Primary Heart Involvement

    Caya Gharibian1, Vanessa Lupi1, Alexander Gotschy1, Mike Becker2, Rucsandra Dobrota1, Muriel Elhai3, Sinziana Muraru1, Suzana Jordan1, Anna-Maria Hoffmann-Vold4, Oliver Distler5, Robert Manka1, Cosimo Bruni1 and Carina Mihai1, 1University Hospital Zurich, University of Zurich, Zurich, Switzerland, 2Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 3University Hospital zurich, Zürich, Switzerland, 4Oslo University Hospital, Oslo, Norway, 5Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: A definition of primary heart involvement (pHI) in systemic sclerosis (SSc) was recently developed (Bruni C et al. J Scleroderma Relat Disord. 2022;7:24-32). Cardiac…
  • Abstract Number: 0689 • ACR Convergence 2024

    Arrhythmic Burden, Myocardial Markers, and Long-term Survival in Distinct Cardiac Magnetic Resonance Subsets of Systemic Sclerosis

    Silvia Laura Bosello1, Enrico De Lorenzis2, Giacomo De Luca3, Antonio Tonutti4, veronica Batani5, Pier Giacomo Cerasuolo6, Gerlando Natalello7, Lucia Lanzo6, Gabriella Alonzi6, Silvia Fiore6, Stefano Di Murro6, Andrea Zoli6, Valentina Boni6, Riccardo Marano8, Francesca Augusta Gabrielli9, Francesco Del Galdo10, Dan Knight11, Vivek Muthurangu11, Christopher Denton12, Maria De Santis4, Marco Matucci Cerinic5 and Maria Antonietta D'Agostino13, 1Unit of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 2Catholic University of the Sacred Heart, Roma, Rome, Italy, 3Vita-Salute San Raffaele University & IRCCS San Raffaele Hospital, Milan, Milan, Italy, 4Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy, 5Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, 6Division of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 7Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, 8Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy, 9Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 10University of Leeds, Leeds, United Kingdom, 11UCL Department of Cardiac MRI, University College London (Royal Free Campus), London, United Kingdom, 12University College London, Northwood, United Kingdom, 13Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy

    Background/Purpose: Cardiac involvement in Systemic Sclerosis (SSc) is widely recognized as heterogeneous and, when clinically evident, it is associated with a poor prognosis. Recently, five…
  • Abstract Number: 0705 • ACR Convergence 2024

    Identification of Risk Factors for Incident Cardiomyopathy in Patients with Systemic Sclerosis

    Ji Soo Kim1, Rachel Wallwork1, Carrie Richardson2, Adrianne Woods3, Monica Mukherjee4, Steven Hsu4, Julie Paik1, Christopher Mecoli1, Laura Hummers5, Fredrick Wigley6, Scott Zeger1 and Ami Shah7, 1Johns Hopkins University, Baltimore, MD, 2Northwestern University, Chicago, 3Johns Hopkins University Division of Rheumatology, Baltimore, MD, 4Johns Hopkins University Division of Cardiology, Baltimore, MD, 5Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Ellicott City, MD, 6Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Baltimore, MD, 7Division of Rheumatology, Johns Hopkins University, Ellicott City, MD

    Background/Purpose: Cardiac involvement in systemic sclerosis (SSc) is one of the leading causes of scleroderma-associated death. There are limited data examining risk factors for incident…
  • Abstract Number: 0712 • ACR Convergence 2024

    Efficacy of Sacubitril/Valsartan in Patients with Systemic Sclerosis and Heart Failure: A Retrospective Analysis

    Nouran Eshak1, Mahmoud Abdelnabi2, Jaxon Quillen1, Michael Pham1, Joseph Hentz1 and Vivek Nagaraja1, 1Mayo Clinic Arizona, Scottsdale, AZ, 2Mayo Clinic Arizona, Phoenix, AZ

    Background/Purpose: Cardiac involvement in systemic sclerosis (SSc) is common, underdiagnosed, and manifests variably. Myocardial involvement can manifest as left heart failure with preserved or reduced…
  • Abstract Number: 1014 • ACR Convergence 2024

    Rural-dwelling Patients with Rheumatoid Arthritis or Those with Lower Income Are More Likely to Be Admitted for Myocardial Infarction in the U.S. and Have Worse Outcomes

    Sumanth Chandrupatla1 and Jasvinder Singh2, 1University of Alabama at Birmingham, Birmingham, AL, 2Baylor College of Medicine, Birmingham, AL

    Background/Purpose: We aimed to assess whether there is a rural-urban disparity in the incidence of myocardial infarction (MI) hospitalization in patients with rheumatoid arthritis (RA).Methods:…
  • Abstract Number: 0032 • ACR Convergence 2024

    Increased Expression of Malondialdehyde-Acetaldehyde and Citrullinated Proteins in Myocardial Tissues During the Early Evolution of Collagen-Induced Arthritis

    Wenxian Zhou1, Michael Duryee2, Nozima Aripova2, Jill Poole2, Carlos Hunter2, Amy Nelson2, Tate Johnson2, Daniel Anderson3, Geoffrey Thiele2 and Ted Mikuls2, 1University of Nebraska Medical Center, Bellevue, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University of Nebraska Medical Center, Durham, NC

    Background/Purpose: The risk of heart failure (HF) is increased in patients with rheumatoid arthritis (RA), although mechanisms of myocardial dysfunction underlying HF development in RA…
  • Abstract Number: 1097 • ACR Convergence 2024

    CERT Score as a Potential Tool to Predict Cardiovascular Risk in Gout and Hyperuricemia

    Blanka Stiburkova1, Aleš Kvasnička2, Barbora Pisklakova2, Jakub Rozhon2, Karel Pavelka3 and David Friedecky2, 1Institute of Rheumatology, Prague, Czech Republic and Department of Paediatrics and Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic, Prague, Czech Republic, 2Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic, Olomouc, Czech Republic, 3Institute of Rheumatology and Charles University, Praha, Czech Republic

    Background/Purpose: Asymptomatic hyperuricemia and gout are two clinical conditions associated with a high risk of cardiovascular events and mortality. Recent data suggest that the number…
  • Abstract Number: 0173 • ACR Convergence 2024

    Systemic Lupus Erythematosus Mortality—United States, 2018–2022

    Danielle Dawson1, Kurt Greenlund2 and Kamil Barbour2, 1CDC, Atlanta, GA, 2CDC, Alpharetta, GA

    Background/Purpose: Mortality due to cardiovascular disease, infections, and renal disease is elevated in people with systemic lupus erythematosus (SLE) compared with the general population, but…
  • Abstract Number: 1559 • ACR Convergence 2024

    Vectorcardiography for Identification of Systemic Sclerosis Patients at Risk for Pulmonary Hypertension

    S. Ahmed1, Eva Hoekstra2, Katie van der Wouden2, Sum-Che Man2, Kees Swenne2, Madelon Vonk3, Anna-Maria Hoffmann-Vold4, Cosimo Bruni5, Udo Mulder6, Thomas Huizinga7, H.W. Vliegen2 and Jeska de Vries-Bouwstra2, 1Leiden University Medical Centre, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 4Oslo University Hospital, Oslo, Norway, 5University of Zurich, Zurich, Switzerland, 6Universitair Medisch Centrum Groningen, Groningen, Netherlands, 7Department of Rheumatology, Leiden University, Leiden, Netherlands

    Background/Purpose: Pulmonary hypertension (PH) in SSc causes significant disease burden and requires invasive diagnosis with right heart catheterization (RHC). Comprehensive work-up is needed to identify…
  • Abstract Number: 0177 • ACR Convergence 2024

    Rural-urban Disparities in the Myocardial Infarction Hospitalizations in People with Systemic Lupus Erythematosus in the US

    Sumanth Chandrupatla1 and Jasvinder Singh2, 1University of Alabama at Birmingham, Birmingham, AL, 2Baylor College of Medicine, Birmingham, AL

    Background/Purpose: To assess whether rural-urban disparities exist in people with SLE for hospitalization with myocardial infarction (MI)Methods: We used the 2016-2019 U.S. National Inpatient Sample…
  • Abstract Number: 1567 • ACR Convergence 2024

    Systemic Sclerosis Is Associated with Sub-Clinical Abnormalities in Myocardial Energetics, Perfusion and Increased Fibrosis

    Chin Yit Soo1, Nicholas Jex2, Stefano Di Donato3, Lucy Elizabeth Thornton4, Vishal Kakkar5, Riccardo Bixio6, Raluca Tomoaia1, Thomas Anderton2, May Lwin2, Christel Kamani2, Amrit Chowdhary2, Henry Procter1, Sharmaine Thirunavukarasu1, Sindhoora Kotha2, Marilena Giannoudi2, Eylem Levelt2, Sven Plein1, Francesco Delgado6 and Lesley-Anne Bissell7, 1Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, England, United Kingdom, 2Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 31. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 41. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 5University of Leeds, Leeds, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 7Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Primary cardiac involvement in systemic sclerosis (SSc) is heterogenous, poorly defined and associated with significant cardiac morbidity and mortality. The underlying mechanism is not…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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