ACR Meeting Abstracts

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Abstracts tagged "giant cell arteritis"

  • Abstract Number: 0696 • ACR Convergence 2023

    Association of Large-vessel Vasculitis with Inflammatory Bowel Diseases: A European Case-control Study

    Francois Maillet1, Yann Nguyen2, Olivier Espitia3, Laurent Perard4, Carlo Salvarani5, Etienne Rivière6, Cécile-Audrey Durel7, Philippe GUILPAIN8, Luc Mouthon9, Anna Kernder10, Javier Loricera11, Pascal Cohen12, Isabelle Melki13, Claire De Moreuil14, Nicolas Limal15, Arsène Mekinian16, Nathalie Costedoat-Chalumeau17, Nathalie Morel12, Jonathan Boutemy18, Loic Raffray19, Jean-Sébastien Allain20, Valerie Devauchelle21, Isabelle Kone-Paut22, Marc Fabre23, Marie Durel24, Antoine Dossier25, Sébastien Abad26, Marcella Visentini27, Adrien Bigot28, Halil Yildiz29, Olivier Fain30, Maxime Samson31, Guillaume Gondran32, Vered Abitbol1 and Benjamin Terrier33, 1Cochin Hospital, Paris, France, 2Department of Internal Medicine, Hôpital Beaujon, AP-HP, Clichy, France., Montmorency, France, 3CHU de Nantes, Nantes, France, 4CH Saint Hoseph Saint Luc, Lyon, France, 5Azienda USL -IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia, Reggio Emilia, Italy, 6CHU Bordeaux, Bordeaux, France, 7CHU Lyon, Lyon, France, 8University of Montpellier, Montpellier, France, 9Hopital Cochin - Paris University, Paris, France, 10HHU Düsseldorf, Düsseldorf, Germany, 11Hospital Universitario Marqués de Valdecilla, Santander, Spain, 12CHU Cochin, Paris, France, 13Hopital Robert Debré, Sérurier, France, 14CHU de Brest, Brest, France, 15AP-HP, Créteil, France, 16Department of Internal Medicine, Hôpital Saint-Antoine, AP-HP, Paris, France, 17Inserm DR Paris 5, Paris, France, 18CHU de Caen, Caen, France, 19CHU la Réunion, La Réunion, France, 20CHU Rennes, Rennes, France, 21UBO, Brest, France, 22Department of Pediatric Rheumatology, Reference Centre for Autoinflammatory Disorders CEREMAIA, Bicêtre Hospital, APHP, University of Paris Saclay, Paris, France, 23CH Bourgoin-Jallieu, Bourgoin-Jallieu, France, 24CH Metz, Metz, France, 25AP-HP, Paris, France, 26Avicenne Hospital, Bobigny, France, 27Rome Hospital, Rome, France, 28Tours Hospital, Tours, France, 29Saint Luc Hospital, Bruxelles, Belgium, 30Hopital SAINT ANTOINE APHP, Paris, France, 31Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, 32Limoges Hospital, Limoges, France, 33Department of Internal Medicine, Hôpital Cochin, AP-HP, Paris, France

    Background/Purpose: The association of large vessel vasculitis (LVV), whether Takayasu arteritis (TA) or giant cell arteritis (GCA), with inflammatory bowel disease (IBD) is a rare…
  • Abstract Number: 1645 • ACR Convergence 2023

    Aortic Dilatation and PET/CT Vascular Activity at Diagnosis and 5 Years in an Inception Giant Cell Arteritis (GCA) Cohort

    Anthony Sammel1, Ivan Ho Shon2, Daniel Moses1, Fredericks Stacey1, Gita Mathur1, Claudia Hillenbrand3, Edward Hsiao4, Schembri Geoffrey4, Rodger Laurent4 and Eva Wegner2, 1Prince of Wales Hospital, Randwick, Australia, 2The Prince of Wales Hospital, Sydney, Australia, 3University of NSW, Randwick, Australia, 4Royal North Shore Hospital, St. Leonards, Australia

    Background/Purpose: Aortic dilatation is typically a late complication of giant cell arteritis (GCA) but there are no tools to risk stratify patients at the time…
  • Abstract Number: 2391 • ACR Convergence 2023

    Epidemiology and Predictors of Relapse in Giant Cell Arteritis: Results of the ARTESER Register

    Javier Narvaez1, Jesús Sanchez-Costa2, Iñigo Hernández-Rodríguez3, Rafael Benito Melero-Gonzalez4, Eugenio De Miguel5, Irene Monjo6, Maite silva díaz7, LUCIA SILVA FERNANDEZ8, Joaquin Maria Belzunegui Otano9, Jesus Alejandro Valero-Jaimes10, Clara Moriano Morales11, Ismael González12, Julio Sanchez Martin13, Tomas Almorza Hidalgo14, Judit Lluch15, Eva Galindez-Agirregoikoa16, Itziar Calvo-Zorrilla16, Vicente Aldasoro17, Javier Mendizabal18, LYDIA ABASOLO19, PIA LOIS20, Javier Loricera13, Noemi Garrido-Puñal21, ALBERTO MARIANO RUIZ ROMAN22, Santos Castañeda23, Cristina Valero23, Patricia Moya Albarado24, Hector Corominas25, Maria J. García-Villanueva26, Carmen Larena27, Paula V. Estrada-Alarcón28, Vanessa Navarro29, Carles Galisteo30, Anne Riveros-Frutos31, Francisco Miguel Ortiz Sanjuan32, Selene Labrada-Arrabal33, María Alcalde34, Clara Molina Almela35, Carlos Garcia Porrua36, Maria García-González37, Margarida Rocha38, Antonio Juan Mas39, Miguel A Gonzalez-Gay40 and Ricardo Blanco41, 1Hospital Universitario de Bellvitge, Barcelona, Spain, 2Unidad de Investigación de la Sociedad Española de Reumatología, Madrid, Spain, 3Hospital do Meixoeiro. Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 4CHU Vigo, O Carballino, Spain, 5Hospital Universitario La Paz, Madrid, Spain, 6University Hospital La Paz, Madrid, Spain, 7Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC)., A Coruña, Spain, 8Complejo Hospitalario Universitario de la Coruña, Pontevedra, Spain, 9University Hospital Donostia, Donostia-San Sebasti, Spain, 10Hospital Bidasoa, Irún, Spain, 11Rheumatology, Hospital Universitario de León, León, Spain, 12Hospital Universitario de León, León, Spain, 13Hospital Universitario Marqués de Valdecilla, Santander, Spain, 14Hospital Universitario 12 de Octubre, Madrid, Spain, 15Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 16Basurto University Hospital, Bilbao, Spain, 17Hospital Universitario de Navarra, Pamplona, Spain, 18Complejo Hospitalario de Navarra, Pamplona, Spain, 19Hospital Clínico San Carlos, Madrid, Spain, 20Hospital Clinico San Carlos, Madrid, Spain, 21Hospital Universitario Virgen del Rocío, Sevilla, Spain, 22Department of Rheumatology, Hospital Universitario Virgen del Rocío, Sevilla, Spain, 23Hospital Universitario de la Princesa, Madrid, Spain, 24Hospital Universitario de Sant Pau, Barcelona, Spain, 25Hospital Universitario Sant Pau, Rheumatology, Barcelona, Spain, 26Hospital Ramón y Cajal, Madrid, Spain, 27Hospital Universitario Ramon y Cajal, Madrid, Spain, 28Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, 29Hospital de Sant Joan Despí – Moises Broggi, Barcelona, Spain, 30Hospital Universitario Parc Taulí, Sabadell, Spain, 31Hospital Universitario Germans Trias i Pujol, Barcelona, Spain, 32Hospital Universitario y Politecnico La Fe, Valencia, Spain, 33Hospital del Mar, Barcelona, Spain, 34Hospital Severo Ochoa, Madrid, Spain, 35Hospital General de Valencia, Valencia, Spain, 36Hospital Universitario Lucus Augusti, Lugo, Spain, 37Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 38Osakidetza, Bilbo, Spain, 39Hospital Universitario Son Llàtzer, Mallorca, Spain, 40IDIVAL and School of Medicine, UC, Santander; Department of Rheumatology, IIS-Fundación Jiménez Díaz, Madrid, Santander, Spain, 41Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: The relapse rate of treated patients with giant cell arteritis (GCA) varied widely in observational series and randomized controlled trials. This study aimed to…
  • Abstract Number: 2408 • ACR Convergence 2023

    The Use of the Southend GCA Probability Score (GCAPS) in Assessing the Risk of Giant Cell Arteritis in Australian Ophthalmological and General Medical Hospital Cohorts

    Eloise Norman1, Clare Fraser2, Mitchell Lawlor3 and Anthony Sammel4, 1Prince of Wales Hospital, Randwick, Australia, 2Save Sight Institute, The University of Sydney, Sydney, Australia, 3Sydney and Sydney Eye Hospital, Sydney, Australia, 4The Prince of Wales Hospital, Sydney, Australia

    Background/Purpose: The rate of positive temporal artery biopsies (TAB) in patients with suspected giant cell arteritis (GCA) varies widely, indicating the need for better pre-test…
  • Abstract Number: 2558 • ACR Convergence 2023

    Aortic Aneurysms in a Multicenter Cohort of 196 Patients with Aortitis Related to Giant Cell Arteritis Treated with Tocilizumab

    Fernando López1, Javier Loricera2, Adrián Martín-Gutiérrez3, Carmen Secada3, Santos Castañeda4, Clara Moriano Morales5, Javier Narvaez6, Vicente Aldasoro7, Olga Maiz8, Rafael Benito Melero-Gonzalez9, PALOMA VELA10, Susana Romero Yuste11, Eugenio De Miguel12, Eva Galindez-Agirregoikoa13, Jesús Carlos Fernández López14, Ivan Ferraz Amaro15, Julio Sánchez-Martín3, Jose L. Callejas16, Patricia Moya Albarado17 and Ricardo Blanco18, 1Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, 4Hospital Universitario de la Princesa, Madrid, Spain, 5Rheumatology, Hospital Universitario de León, León, Spain, 6Hospital Universitario de Bellvitge, Barcelona, Spain, 7Hospital Universitario de Navarra, Pamplona, Spain, 8Hospital Universitario de Donostia. San Sebastián, Spain., Donosti, Spain, 9CHU Vigo, O Carballino, Spain, 10Rheumatology, Hospital General Universitario Alicante, Alicante, Spain, 11Complexo Hospitalario Universitario, Pontevedra, Spain, 12Hospital Universitario La Paz, Madrid, Spain, 13Basurto University Hospital, Bilbao, Spain, 14Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 15Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 16Unit of Systemic Autoimmune Diseases, Hospital San Cecilio, Granada, Spain, 17Hospital Universitario de Sant Pau, Barcelona, Spain, 18Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Aortic aneurysms is a serious complication that can occur in patients with giant cell arteritis (GCA) (1-2). Tocilizumab (TCZ) is approved for GCA. Nevertheless,…
  • Abstract Number: 0468 • ACR Convergence 2022

    Ultrasound Wall Thickness in the Differential Diagnosis of Atherosclerosis and Large Vessel Giant Cell Arteritis

    Eugenio De Miguel1, Jose Maria Mostaza2, Carlos Lahoz2, Juan Molina3, Elisa Fernandez-Fernandez1 and Irene Monjo4, 1Hospital Universitario La Paz, Madrid, Spain, 2Hospital Carlos III, Madrid, Spain, 3Hospital General Universitario Gregorio Marañón, Madrid, Spain, 4Hospital Universitario La Paz - IdiPAZ, Madrid, Spain

    Background/Purpose: Giant cell arteritis (GCA) is the most common vasculitis in the elderly and large vessel involvement (LV-GCA) occurs in up to 50% of cases.…
  • Abstract Number: 0484 • ACR Convergence 2022

    Epidemiology and Predictors of Relapse in Giant Cell Arteritis: A Systematic Review and Meta-analysis

    Lien Moreel1, Albrecht Betrains1, Geert Molenberghs2, Steven Vanderschueren1 and Daniel Blockmans1, 1University Hospitals Leuven, KU Leuven, Leuven, Belgium, 2KU Leuven, Leuven, Belgium

    Background/Purpose: The aim of this study was to estimate the timing of relapse, the prevalence of multiple relapses and the predictors of relapse in patients…
  • Abstract Number: 1202 • ACR Convergence 2022

    Clinical Profile and Trend of Vasculitis in Patients with Acute Coronary Syndrome – Insight from National Database 2010 to 2019

    Palak Shah1, Ana Arevalo2, Rasha Alaameri3, Brinda Basida4, Urja Nagadia5, Sanket Basida5, shobhana Chaudhari6 and Monil Majmundar7, 1Metropolitan Hospital Center, New York Medical College, New York, NY, 2University of Chicago, Chicago, IL, 3New York Medical College/ Metropolitan Program, New York, NY, 4DMC/Sinai Grace Hospital, Detroit, MI, 5University of Missouri, Columbia, MO, 6NYC Health and Hospital/Metropolitan Hospital, New York, NY, 7University of Kansas Medical Center, Kansas City, KS

    Background/Purpose: Vasculitides are characterized by inflammation of vessel walls with reactive damage to mural structures leading to compromise of the lumen. Vasculitides also accelerate atherosclerosis…
  • Abstract Number: 0469 • ACR Convergence 2022

    Factors Associated with Corticosteroid Dosing in the Management of Giant Cell Arteritis

    Loukas Kakoullis and Shiv Sehra, Mount Auburn Hospital, Cambridge, MA

    Background/Purpose: Corticosteroids are the cornerstone of therapy in patients with giant cell arteritis (GCA). Tapering regiments vary considerably in both dose and duration, while relapses…
  • Abstract Number: 0485 • ACR Convergence 2022

    Assessing the Effectiveness of Tocilizumab in Newly Diagnosed Giant Cell Arteritis versus Refractory/recurrent Giant Cell Arteritis in Clinical Practice

    Julio Sánchez-Martín1, Javier Loricera2, Clara Moriano3, Santos Castañeda4, F. Javier Narváez5, Vicente Aldasoro6, Olga Maiz7, Rafael Melero8, Juan Ignacio Villa Blanco9, Paloma Vela-Casasempere10, Susana Romero Yuste11, José Luis Callejas12, Eugenio De Miguel13, Eva Galíndez-Agirregoikoa14, Francisca Sivera15, Jesus Fernandez16, Carles Galisteo17, Ivan Ferraz Amaro18, Lara Sánchez-Bilbao1, Monica Calderon-Goercke19, Miguel Ángel González-Gay20 and Ricardo Blanco2, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Complejo Asistencial Universitario de León, León, Spain, 4Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 5Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, 6Hospital Universitario de Navarra, Pamplona, Spain, 7Hospital Universitario de Donostia, San Sebastián, Spain, 8Complexo Hospitalario Universitario de Vigo, Vigo, Spain, 9Sierrallana Hospital, Torrelavega, Spain, 10Hospital General Universitario Alicante, Alicante, Spain, 11Complexo Hospitalario Universitario, Pontevedra, Spain, 12Hospital San Cecilio, Granada, Spain, 13Hospital Universitario La Paz, Madrid, Spain, 14Basurto University Hospital, Bilbao, Spain, 15Hospital Universitario de Elda, San Vicente del Raspeig, Spain, 16Hospital de La Coruña, La Coruña, Spain, 17Hospital Parc Tauli,, Sabadel, Spain, 18Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 19Hospital de Sierrallana, Torrelavega, Spain, 20Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: Tocilizumab (TCZ) is the only biologic drug approved in giant cell arteritis (GCA), based in two clinical trials (CT) (1,2). CT included selected patients…
  • Abstract Number: 1245 • ACR Convergence 2022

    Imaging Use and Medication Management in Giant Cell Arteritis

    Aradhna Agarwal1, Reid Weisberg1, Jiby Mathew2, Andreas Reimold3 and Kyawt Shwin1, 1UT Southwestern, Dallas, TX, 2VA North Texas Health Care System/Dallas VA Medical Center, Dallas, TX, 3University of Texas Southwestern Medical Center, Dallas, TX

    Background/Purpose: Giant cell arteritis (GCA) affects medium and large arteries. Although temporal artery biopsy (TAB) remains the gold standard for patients with cranial GCA, patients…
  • Abstract Number: 0470 • ACR Convergence 2022

    Long-term Efficacy of Tocilizumab Monotherapy After Ultra-short Glucocorticoid Administration to Treat Giant Cell Arteritis – One Year Follow-up of the GUSTO Trial

    Lisa Christ1, Luca Seitz2, Godehard Scholz1, Lukas Buetikofer3, Florian Kollert1, Stephan Reichenbach4 and Peter Villiger5, 1Department of Rheumatology and Immunology, University of Bern, Inselspital, Bern, Switzerland, 2Department of Rheumatology and Immunology, University of Bern, Inselspital, Switzerland, 3CTU Bern, University of Bern, Bern, Switzerland, 4University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland, 5Medical Center Monbijou, Rheumatology and Immunology, Bern, Switzerland

    Background/Purpose: Two randomised controlled trials (RCT) [1, 2] demonstrated a glucocorticoid (GC)-sparing effect of tocilizumab (TCZ) of at least 50% in the treatment of giant…
  • Abstract Number: 0486 • ACR Convergence 2022

    Gene Expression Profile of Temporal Artery Tissue and Whole Blood in Giant Cell Arteritis

    Marcia Friedman1, Daniel Albert2, Dongseok Choi3, Hillary Stiefel2, Colin Oglesbee-Venghaus2, Kimberly Ogle2, Christina Harrington4, David Wilson2 and James T. Rosenbaum5, 1Oregon Health and Science University, Division of Arthritis and Rheumatic Diseases, Portland, OR, 2Casey Eye Institute, Portland, OR, 3OHSU-PSU School of Public Health, Portland, OR, 4Oregon Health & Science University, Portland, OR, 5Legacy Devers Eye Institute, Portland, OR

    Background/Purpose: Diagnosing giant cell arteritis GCA is notoriously challenging, as there are no reliable blood biomarkers and temporal artery biopsy (TAB) has a sensitivity of…
  • Abstract Number: 1257 • ACR Convergence 2022

    Assessing the Effectiveness of Tocilizumab in Giant Cell Arteritis by PET: Multicenter Study of 101 Patients of Clinical Practice

    Julio Sánchez-Martín1, Javier Loricera1, Santos Castañeda2, Clara Moriano3, F. Javier Narváez4, Vicente Aldasoro5, Olga Maiz6, Rafael Melero7, Juan Ignacio Villa Blanco8, Paloma Vela-Casampere9, Susana Romero Yuste10, José Luis Callejas11, Eugenio De Miguel12, Eva Galíndez-Agirregoikoa13, Francisca Sivera14, Jesus Fernandez15, Carles Galisteo16, Ivan Ferraz Amaro17, Lara Sánchez-Bilbao1, Monica Calderon-Goercke18, Miguel Ángel González-Gay19 and Ricardo Blanco20, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 3Complejo Asistencial Universitario de León, León, Spain, 4Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, 5Hospital Universitario de Navarra, Pamplona, Spain, 6Hospital Universitario de Donostia, San Sebastián, Spain, 7Complexo Hospitalario Universitario de Vigo, Vigo, Spain, 8Sierrallana Hospital, Torrelavega, Spain, 9Hospital General Universitario Alicante, Alicante, Spain, 10Complexo Hospitalario Universitario, Pontevedra, Spain, 11Hospital San Cecilio, Granada, Spain, 12Hospital Universitario La Paz, Madrid, Spain, 13Basurto University Hospital, Bilbao, Spain, 14Hospital Universitario de Elda, San Vicente del Raspeig, Spain, 15Hospital de La Coruña, La Coruña, Spain, 16Hospital Parc Tauli,, Sabadel, Spain, 17Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 18Hospital de Sierrallana, Torrelavega, Spain, 19Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 20Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Positron emission tomography (PET) is one of the tools available for the diagnosis of extracranial large-vessel vasculitis (1-5). Tocilizumab (TCZ) has shown efficacy in…
  • Abstract Number: 0471 • ACR Convergence 2022

    Serum Proteomics in Giant Cell Arteritis: Findings of the Giant Cell Arteritis Treatment with Ultra-short Glucocorticoids and Tocilizumab Trial (The GUSTO Trial)

    Lisa Christ1, Andrea Gloor2, Florian Kollert1, Timo Gaber3, Frank Buttgereit3, Stephan Reichenbach4 and Peter Villiger5, 1Department of Rheumatology and Immunology, University of Bern, Inselspital, Bern, Switzerland, 2Department of Internal Medicine, University of Bern, Inselspital, Bern, Switzerland, 3Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin / DRFZ Berlin, Berlin, Germany, 4University of Bern, Institute for Social and Preventive Medicine, Bern, Switzerland, 5Medical Center Monbijou, Rheumatology and Immunology, Bern, Switzerland

    Background/Purpose: Measuring disease activity in patients with giant cell arteritis (GCA) remains challenging since appropriate biomarkers are missing, particularly, if tocilizumab (TCZ) is prescribed which…
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