Abstracts tagged "gender"

Abstract Number: 1153 • ACR Convergence 2022
Differentially Expressed Genes in Males and Females with Ankylosing Spondylitis (AS): Transcriptomics of IL-17-producing Cells in Patients with AS
Chan Mi Lee¹, Ricky Chan², Maricela Haghiac³ and Marina Magrey⁴, ¹University Hospitals, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH, ³Metrohealth Medical Center, Cleveland, OH, ⁴Case Western Reserve University, University Hospitals, Richfield, OH
Background/Purpose: Unlike most autoimmune diseases, ankylosing spondylitis (AS) is more frequently diagnosed in men (3:1) and with a higher radiographic progression compared to women. Th17…
Abstract Number: 1158 • ACR Convergence 2022
Differential Plasma Levels of S100 Proteins in Male versus Female Patients with Ankylosing Spondylitis
Chan Mi Lee¹, Maricela Haghiac² and Marina Magrey³, ¹University Hospitals, Cleveland, OH, ²Metrohealth Medical Center, Cleveland, OH, ³Case Western Reserve University, University Hospitals, Richfield, OH
Background/Purpose: S100 proteins are a family of 25 calcium-binding cytosolic proteins which are involved in stress and inflammatory responses. S100A4 acts as a negative regulator…
Abstract Number: 1334 • ACR Convergence 2021
How Does Gender Affect Secukinumab Treatment Outcomes and Retention Rates in Patients with Psoriatic Arthritis? – Real World Data from a German Observational Study
Uta Kiltz¹, Jan Brandt-Jrgens², Peter Kästner³, Elke Riechers⁴, Daniel Peterlik⁵ and Hans-Peter Tony⁶, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Rheumatologische Schwerpunktpraxis, Berlin, Germany, ³Ambulantes Rheumazentrum Erfurt, Erfurt, Germany, ⁴Department for Rheumatology and Immunology, Hannover Medical University, Hannover, ⁵Novartis Pharma GmbH, Nürnberg, Germany, ⁶Universitätsklinikum Würzburg, Wuerzburg, Germany
Background/Purpose: Gender disparities in PsA can affect natural course of disease, clinical presentation and response to medication1. The German non-interventional study AQUILA provides real-world data…
Abstract Number: 1799 • ACR Convergence 2021
Gender Based Differences in Clinical and Sonographic Assessment Among Patients with Psoriatic Arthritis
Victoria Furer¹, Jonathan Wollman², David levartovsky³, Valerie Aloush³, Sara Borok Lev-Ran⁴, Daphna Paran⁵, Ori Elkayam³ and Ari Polachek⁶, ¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²Tel Aviv Medical Center, Herzliya, Israel, ³Tel Aviv Medical Center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Tel AViv, Israel, ⁵Tel Aviv Sourasky Medical Center-Ichilov Hospital, Even Yehuda, Israel, ⁶Sourasky Medical Center, Petah-Tikva, Israel
Background/Purpose: Psoriatic arthritis (PsA) can affect differently women and men. Ultrasound (US) is an important tool in the evaluation of disease activity of PsA. To…
Abstract Number: 0369 • ACR Convergence 2021
High Frequency of Complications in Axial Spondyloarthropathy Pregnancies: Emerging Data from the Ankylosing Spondylitis Registry of Ireland
Sinead Maguire¹, Phil Gallagher² and Finbar (Barry) O'Shea¹, ¹St James's Hospital, Dublin, Ireland, ²St Vincent's Hospital, Dublin, Ireland
Background/Purpose: National registries are excellent sources of data to allow analysis of inflammatory arthritis such as axial spondyloarthropathy (axSpA). Our understanding of axSpA has evolved…
Abstract Number: 0383 • ACR Convergence 2021
Differences Between Male vs. Female Presenting with Back Pain in an Integrated Delivery System
Aniket Kawatkar¹, Esther Yi², Erika Estrada¹, Jose Pio¹, Cecilia Portugal¹, David Yi¹ and Steve Lee³, ¹Kaiser Permanente Southern California, Pasadena, CA, ²Novartis Pharmaceuticals Corporation, Weehawken, NJ, ³Southern California Permanente Medical Group, Fontana, CA
Background/Purpose: Back pain exerts significant economic burden and in its inflammatory form is the main clinical symptom of axial spondylarthritis. We evaluated differences in patient…
Abstract Number: 0406 • ACR Convergence 2021
Gender Differences in Clinical Features and Outcomes of Systemic Sclerosis: Analysis of Reuma.pt/SSc Registry
Raquel Freitas¹, Patrícia Martins², Eduardo Dourado², Tânia Santiago³, Francisca Guimarães⁴, Bruno Fernandes⁵, Salomé Garcia⁶, Beatriz Samões⁷, Ana Pinto⁸, Nuno Gonçalves⁹, Maria Lourenço¹⁰, Emanuel Costa¹¹, Margarida Rocha¹², Maura Couto¹³, Ana Catarina Duarte¹, Filipe Araújo¹⁴, Inês Cordeiro², Fátima Godinho¹, Catarina Resende¹⁵, Maria Joo Salvador¹⁶, Ana Cristina Cordeiro¹ and Maria José Santos¹⁷, ¹Hospital Garcia de Orta, Rheumatology department, Almada, Portugal, ²Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET); Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal, ³Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ⁴Unidade Local de Saúde do Alto Minho, Rheumatology department, Ponte de Lima, Portugal, ⁵Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Braga, Portugal, ⁶Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Porto, Portugal, ⁷Rheumatology Department, Centro Hospitalar Vila Nova de Gaia, VIla Nova de Gaia, Portugal, ⁸Local Health Unit of Guarda, Portugal, Barcelos, Portugal, ⁹Centro Hospitalar Lisboa Ocidental, Rheumatology Department; Hospital Central do Funchal, Lisboa, Portugal, ¹⁰Hospital Egas Moniz, Barcelos, Portugal, ¹¹Hospital de Braga, Braga, Portugal, ¹²Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Faro, Portugal, ¹³Centro Hospitalar Tondela - Viseu, Rheumatology Department, Linda a Velha, Portugal, ¹⁴Hospital de Sant'Ana, Rheumatology and Osteoporosis department, Parede, Portugal, ¹⁵Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Lisbon, Portugal, ¹⁶Centro Hospitalar e Universitário de Coimbra, Rheumatology Department, Coimbra, Portugal, ¹⁷Rheumatology Department, Hospital Garcia de Orta, Almada, Portugal
Background/Purpose: Systemic sclerosis (SSc) is a rare connective tissue disease of unknown etiology, with a broad spectrum of clinical and laboratory features. Evidence for the…
Abstract Number: 0578 • ACR Convergence 2021
Hyperinsulinemic Diet and Increased Risk of Female Gout: 2 Prospective Cohort Studies of US Women over 30 Years
Natalie McCormick¹, Chio Yokose², Na Lu³, Amit Joshi¹ and Hyon K. Choi⁴, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Waltham, MA, ³Arthritis Research Canada, Vancouver, BC, Canada, ⁴Massachusetts General Hospital, Lexington, MA
Background/Purpose: Gout and the metabolic (insulin resistance) syndrome frequently coexist. Intravenous insulin has been shown to raise serum urate (SU) levels in physiologic studies1 and…
Abstract Number: 0592 • ACR Convergence 2021
Gender Modifies the Effect of Rheumatoid Arthritis on All-Cause Mortality
Srikanta Banerjee¹ and Stephanie Falls², ¹Walden University, Leola, ²PA Department of Health, Leola
Background/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease which predominantly affects joints with varying severity. While RA has been found to be…
Abstract Number: 0597 • ACR Convergence 2021
Sex Differences in Multimorbidity Between Patients with Systemic Lupus Erythematosus and Comparators in a Large Nationwide US Study
Ali Duarte-Garcia¹, Herbert Heien¹, Nilay Shah¹ and Cynthia Crowson², ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have an increased burden of multimorbidity. Although many comorbidities may vary by sex and men with lupus may…
Abstract Number: 0620 • ACR Convergence 2021
Is There a Difference in Disease Activity Between Genders in Axial Spondyloarthritis? 6-year Longitudinal Data from a Large National Cohort
krystel aouad¹, Anne Tournadre², Florian LUCASSON¹, Daniel Wendling³, Anna Molto⁴, Bruno Fautrel⁵ and Laure Gossec⁶, ¹Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France, ²Rheumatology Department, Université Clermont Auvergne, CHU Clermont-Ferrand, INRAE, UNH UMR 1019, Clermont-Ferrand, France, ³Service de rhumatologie, CHU de Besançon, Besançon, France, ⁴Rheumatology department, Cochin hospital, APHP, Paris, France, ⁵Pitié Salpêtrière Hospital, APHP, Sorbonne Université, Paris, France, ⁶Sorbonne Université; APHP, Rheumatology Department, Pitié-Salpêtrière Hospital, Paris, France
Background/Purpose: Recent data suggest differences between men and women with axial spondyloarthritis (axSpA), in terms of disease activity, disease progression and treatment response [1-3]. Overall,…
Abstract Number: 0677 • ACR Convergence 2021
Pro-Inflammatory Diet and Increased Risk of Incident Female Gout: 30-Year Prospective Cohort Study of >170,000 Pre- and Post-Menopausal US Women
Natalie McCormick¹, Chio Yokose², Na Lu³, Amit Joshi¹ and Hyon K. Choi⁴, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Waltham, MA, ³Arthritis Research Canada, Vancouver, BC, Canada, ⁴Massachusetts General Hospital, Lexington, MA
Background/Purpose: Globally, the prevalence of gout is rising in females more than males,1 but data on modifiable risk factors for female gout are scarce. Emerging…
Abstract Number: 0900 • ACR Convergence 2021
The Phenomenon of Fused Sacroiliac Joints but Absent Syndesmophytes in Long Standing Ankylosing Spondylitis Patients: Data from a Prospectively Followed Cohort
Lauren Ridley¹, Mark Hwang², John Reveille³, Lianne Gensler⁴, Mariko Ishimori⁵, Matthew Brown⁶, Mohammad Rahbar⁷, Amirali Tahanan⁸, Michael Ward⁹, Michael Weisman¹⁰ and Thomas Learch¹¹, ¹McGovern Medical School, Katy, TX, ²McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ³Division of Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, ⁴Department of Rheumatology, University of California San Francisco, San Francisco, CA, ⁵Cedars-Sinai Health System, Los Angeles, CA, ⁶King's College London, London, United Kingdom, ⁷Division of Clinical and Translational Sciences, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX, ⁸McGovern Medical School, Houston, TX, ⁹Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States, Rockville, MD, ¹⁰Adjunct Professor of Medicine, Stanford University; Distinguished Professor of Medicine Emeritus, David Geffen School of Medicine at UCLA, Los Angeles, CA, ¹¹Cedars-Sinai, Los Angeles, CA
Background/Purpose: Ankylosing Spondylitis describes disorders of inflammation and damage to the spine and sacroiliac (SI) joints. Clinicians have observed, on occasion, AS subjects with fused…
Abstract Number: 0909 • ACR Convergence 2021
How Does Gender Affect Secukinumab Treatment Outcomes and Retention Rates in Patients with Ankylosing Spondylitis? – Real World Data from a German Observational Study
Uta Kiltz¹, Jan Brandt-Jrgens², Peter Kästner³, Elke Riechers⁴, Daniel Peterlik⁵ and Hans-Peter Tony⁶, ¹Rheumazentrum Ruhrgebiet Herne, Ruhr-Universität Bochum, Herne, Germany, ²Rheumatologische Schwerpunktpraxis, Berlin, Germany, ³Ambulantes Rheumazentrum Erfurt, Erfurt, Germany, ⁴Department for Rheumatology and Immunology, Hannover Medical University, Hannover, ⁵Novartis Pharma GmbH, Nürnberg, Germany, ⁶Universitätsklinikum Würzburg, Wuerzburg, Germany
Background/Purpose: Current studies suggest that the phenotype of spondyloarthritis differs between genders and that this may influence the subsequent diagnostic approach and therapeutic decisions1. The…
Abstract Number: 1322 • ACR Convergence 2021
Body Mass Index (BMI) Underestimates Obesity in Females with Axial Spondyloarthropathy
Sinead Maguire¹, Wilson Fiona², Phil Gallagher³ and Finbar (Barry) O'Shea¹, ¹St James's Hospital, Dublin, Ireland, ²Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland, ³St Vincent's Hospital, Dublin, Ireland
Background/Purpose: Worldwide prevalence of obesity has been steadily increasing, despite public health campaigns to raise awareness. In axial spondyloarthropathy (axSpA) obesity has been shown to…

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