Abstracts tagged "functional status"

Abstract Number: 2398 • 2018 ACR/ARHP Annual Meeting
Children with Enthesitis Have Worse Quality of Life, Function, and Pain, Irrespective of Their Juvenile Arthritis Category
Dax G. Rumsey¹, Jaime Guzman², Alan Rosenberg³, Adam Huber⁴, Rosie Scuccimarri⁵, Natalie J. Shiff⁶, Alessandra Bruns⁷, Brian M. Feldman⁸ and Dean Eurich⁹, ¹Paediatrics, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ³Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ⁴Dalhousie University, Halifax, NS, Canada, ⁵Department of Pediatrics, McGill University Health Centre, Montreal, QC, Canada, ⁶University of Florida, Gainesville, FL, ⁷Hospitalier de l’Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁸Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁹University of Alberta, Edmonton, AB, Canada
Background/Purpose: To estimate the impact of enthesitis on patient reported outcomes (PROs) in children with juvenile idiopathic arthritis (JIA), irrespective of their JIA category. Methods:…
Abstract Number: 2489 • 2018 ACR/ARHP Annual Meeting
In Clinical Practice a Substantial Group of Rheumatoid Arthritis (RA) Patients on Biologic Therapy (bDMARDs) Has Persistent Moderate Disease Activity Despite Treatment Switches That Correlates with Unfavourable Long-Term Outcome
Irini Genitsaridi^1,2, Irini Flouri³, Argyro Repa², Nestor Avgoustidis², Nikolaos Kougkas², Ioannis Papalopoulos², Styliani Polia², Konstantinos Marias¹, Dimitris Plexousakis⁴, George Bertsias² and Prodromos Sidiropoulos², ¹Computational BioMedicine Laboratory, Institute of Computer Science, Foundation for Research and Technology-Hellas, Heraklio, Greece, ²Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, School of Medicine, Heraklion, Greece, ³Department of Rheumatology, Clinical Immunology and Allergy, University of Crete, School of Medicine, Heraklio, Greece, ⁴Information Systems Laboratory, Institute of Computer Science, Foundation for Research and Technology-Hellas, Heraklio, Greece
Background/Purpose: Registry data have shown that treatment with bDMARDs induces remission or LDA (RLDA) in up-to 50% of RA patients. Approximately 30-50% of patients have…
Abstract Number: 223 • 2018 ACR/ARHP Annual Meeting
The Effect of Concomitant Diabetes on RA-Related Outcomes: Results from the Acr’s RISE Registry
Huifeng Yun¹, Fenglong Xie¹, Lang Chen¹, Shuo Yang¹, Leticia Ferri², Evo Alemao², Tammy Curtice² and Jeffrey R. Curtis¹, ¹University of Alabama at Birmingham, Birmingham, AL, ²Bristol-Myers Squibb, Princeton, NJ
Background/Purpose: The impact of concomitant comorbidities on RA outcomes is of high interest, and some evidence suggests that patients (pts) with RA and diabetes may…
Abstract Number: 381 • 2018 ACR/ARHP Annual Meeting
Muscle Endurance Deficits in Myositis Patients Despite Normal Manual Muscle Testing Scores
David Amici^1,2, Iago Pinal-Fernandez^3,4, Ruben Pagkatipunan⁵, Albert Mears⁵, Rebecca De Lorenzo⁶, Eleni Tiniakou⁷, Jemima Albayda³, Julie J. Paik⁷, Thomas E. Lloyd⁸, Lisa Christopher-Stine⁹, Andrew Mammen^8,10 and Tae Chung¹¹, ¹National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Muscle Diseases Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases. National Institutes of Health, Bethesda, MD, ⁵Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ⁷Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁸Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁹Medicine and Neurology, Johns Hopkins University, Baltimore, MD, ¹⁰National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ¹¹Johns Hopkins University, Baltimore, MD
Background/Purpose: To assess muscle function in myositis patients, clinicians typically use manual muscle testing (MMT), a measure of maximal isometric strength. However, patients with high…
Abstract Number: 1137 • 2018 ACR/ARHP Annual Meeting
Prediction Models for Poor Function Outcomes over 10 Years in Persons at High Risk for Knee Osteoarthritis
Leena Sharma¹, Orit Almagor¹, Alison H. Chang¹, C. Kent Kwoh², Michael C. Nevitt³, Marc C. Hochberg⁴, Rebecca D. Jackson⁵, Charles B. Eaton⁶, Jane A. Cauley⁷, Julie Szymaszek⁸ and Joan S. Chmiel¹, ¹Northwestern University, Chicago, IL, ²University of Arizona, Tucson, AZ, ³UCSF, San Francisco, CA, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Ohio State University, Columbus, OH, ⁶Family Medicine, Memorial Hospital of Rhode Island, Pawtucket, RI, ⁷University of Pittsburgh, PIttsburgh, PA, ⁸Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Among persons at high risk for knee osteoarthritis (OA), identifying those who will have function decline is important; instituting prevention strategies in all…
Abstract Number: 1169 • 2018 ACR/ARHP Annual Meeting
Association between Depressive Symptom Subtypes and Disease Severity in Knee Osteoarthritis
Alan Rathbun¹, Megan Schuler², Elizabeth Stuart³, Michelle Shardell⁴, Michelle S. Yau⁵, Joseph Gallo⁶ and Marc C. Hochberg⁷, ¹Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ²Rand Coportation, Boston, MA, ³Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, ⁵Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ⁶Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁷University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Latent and modifiable factors, such as depressive symptoms, may affect the course of knee OA. Depression is clinically heterogeneous, and effects on pain and…
Abstract Number: 1179 • 2018 ACR/ARHP Annual Meeting
Achieving Important Improvement in WOMAC Pain and Function By Three Months Post-Surgery Influences Satisfaction 1 Year Following Total Knee Replacement (TKR)
Aileen Davis¹, Selahadin Ibrahim², Sheilah Hogg-Johnson³, Rosalind Wong⁴, Dorcas Beaton⁵, Bert Chesworth⁶, Rajiv Gandhi⁷, Nizar Mahomed⁸, Anthony V. Perruccio⁹, Vai Rajgopal¹⁰ and James Waddell¹¹, ¹Health Care and Outcomes Research, Krembil Research Institute, University Health Network, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, ²Institute for Work and Health, Toronto, ON, Canada, ³Canadian Memorial Chiropractic College, Toronto, ON, Canada, ⁴Krembil Research Institute, Health Care and Outcomes Research, Toronto, ON, Canada, ⁵University of Toronto, Department of Occupational Science and Occupational Therapy, Rehabilitation Sciences Institute, and the Institute for Health Policy Management and Evaluation, Toronto, ON, Canada, ⁶Western University, London, ON, Canada, ⁷Department of Surgery - Orthopedics, Toronto Western Hospital, Assistant Professor, Department of Surgery, University of Toronto, Toronto, ON, Canada, ⁸Orthopaedics, University Health Network, Toronto, ON, Canada, ⁹Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada, ¹⁰Orthopaedics, Middle Sex Hospital Alliance, Strathroy, ON, Canada, ¹¹Orthopaedics, Saint Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Understanding the impact of the time of achievement of important improvement (II) in pain and function may further understanding of outcome and inform care…
Abstract Number: 1367 • 2018 ACR/ARHP Annual Meeting
Efficacy of Intra-Articular Cntx-4975 for Knee OA Pain Varies with Radiographic Presence of OA in the Opposite Knee
Randall Stevens¹, James Campbell¹, Kimberly Guedes¹, Robin Burges¹, Valerie Smith² and Peter Hanson¹, ¹Centrexion Therapeutics, Boston, MA, ²Premier Research, Durham, NC
Background/Purpose: Nearly 60% of patients with knee OA have unilateral OA; most of those patients develop bilateral OA. CNTX-4975 is a highly purified, synthetic trans-capsaicin…
Abstract Number: 1381 • 2018 ACR/ARHP Annual Meeting
Association of Omeract Core Domains of Pain and Function with Patient Satisfaction after Total Joint Replacement
Susan M. Goodman¹, Bella Y. Mehta², Lisa A. Mandl³, Jackie Szymonifka¹, Mark P. Figgie⁴, Iris Navarro-Millán⁵, Mathias Bostrom⁶, Michael L. Parks⁷, Alexander McLawhorn⁸, Stephen Lyman⁷ and Jasvinder A. Singh⁹, ¹Hospital for Special Surgery, New York, NY, ²Hospital for Special Surgery/Weill Cornell Medicine/Mailman School of Public Health, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Surgery, Hospital for Special Surgery, New York, NY, ⁵Weill Cornell Medicine, New York, NY, ⁶Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, ⁷Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁸Hospital for Special Surgey, New York, NY, ⁹Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Up to 20% of Total Joint Replacement (TJR) patients are dissatisfied, but this is difficult to study as it is challenging to pool data…
Abstract Number: 2171 • 2017 ACR/ARHP Annual Meeting
Functional Measures and Patient Home Self-Assessments in the Idiopathic Inflammatory Myopathies
Amanda Kocoloski¹, Courtney Ward², Diane Koontz², Chester V. Oddis³ and Rohit Aggarwal⁴, ¹Internal Medicine, Division of Rheumatology, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Internal Medicine Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ³Rheumatology/Clinical Immunology, Unviersity of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA, ⁴Medicine / Rheumatology, University of Pittsburgh/University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: Myositis leads to significant morbidity and loss of function. Currently, simple objective measures of patient functional outcomes are lacking. Our aims were to a)…
Abstract Number: 2218 • 2017 ACR/ARHP Annual Meeting
Concurrent Change in Quadriceps Strength and Physical Function over 5 Years in the Multicenter Osteoarthritis Study
Kathryn Bacon¹, Neil Segal², BE Øiestad³, Cora E. Lewis⁴, Michael C. Nevitt⁵, Carrie Brown⁶ and David T. Felson⁷, ¹Clinical Epidemiology Research & Training Unit, Boston University School of Medicine, Boston, MA, ²University of Kansas, Shawnee, KS, ³Oslo and Akershus University College of Applied Sciences, Oslo, Norway, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶Boston University School of Public Health, Boston, MA, ⁷Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Quadriceps weakness is associated with functional limitations and a target in the treatment of knee osteoarthritis (OA). There are limited data on the effect…
Abstract Number: 2263 • 2017 ACR/ARHP Annual Meeting
Obesity Independently Associates with Worse Patient Reported Outcomes in Women with Systemic Lupus Erythematosus
Sarah L. Patterson¹, Gabriela Schmajuk², Kashif Jafri³, Katherine D. Wysham³ and Patricia P. Katz⁴, ¹Division of Rheumatology, University of California, San Francisco, San Francisco, CA, ²San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, ³University of California, San Francisco, San Francisco, CA, ⁴Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Obesity has been shown to exacerbate systemic inflammation in the general population and contributes to worse disease-related outcomes in rheumatoid arthritis. The impact of…
Abstract Number: 2305 • 2017 ACR/ARHP Annual Meeting
Efficacy of Function-Based Exercise Program on Functional Ability, Pain and Quality of Life in Children with Juvenile Idiopathic Arthritis
Ela Tarakci¹, Saime Nilay Baydogan¹, Sezgin Sahin², Amra Adrovic², Kenan Barut² and Ozgur Kasapcopur², ¹Istanbul University, Faculty of Health Science, Division of Physiotherapy and Rehabilitation, Istanbul, Turkey, ²Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases in childhood, affecting at least 1 in 1000 children. Children with JIA,…
Abstract Number: 2372 • 2017 ACR/ARHP Annual Meeting
Obesity and the Impact on Treat to Target Goals and Functional Ability in RA. Results from Two Multi-Centre UK Inception Cohorts
Elena Nikiphorou¹, Sam Norton², Patrick Kiely³ and Adam Young⁴, ¹Academic Rheumatology Department, King's College London, London, United Kingdom, ²Academic Rheumatology, King´s College London, London, United Kingdom, ³St George's Hospital, London, United Kingdom, ⁴University of Hertfordshire, Hertford, United Kingdom
Background/Purpose: The links between inflammation, obesity and joint dysfunction are well established. How these translate into clinical disease activity and functional disability in rheumatoid arthritis…
Abstract Number: 2384 • 2017 ACR/ARHP Annual Meeting
Incidence and Predictors of Dyspnea on Exertion in a Prospective Cohort of Patients with Rheumatoid Arthritis
Jeffrey A. Sparks¹, Tracy Doyle², Beatrice Pan³, Christine Iannaccone⁴, Michelle Frits³, Paul Dellaripa⁵, Ivan Rosas⁵, Bing Lu⁶, Michael Weinblatt⁶, Nancy A. Shadick⁷ and Elizabeth Karlson⁵, ¹Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Pulmonary Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁶Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose : Dyspnea on exertion symptoms often prompt clinical evaluation related to respiratory, cardiovascular, and functional status. However, the incidence and predictors of clinically significant…

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