ACR Meeting Abstracts

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Abstracts tagged "Fracture"

  • Abstract Number: 0544 • ACR Convergence 2020

    Risk Factors for Lumbar Vertebral Osteoporosis Do Not Reflect Factors Traditionally Associated with Osteoporosis at the Hip

    Marwan Bukhari1 and Mrinalini Dey2, 1Rheumatology Department, University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom, 2Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom

    Background/Purpose: The most common site of osteoporotic fragility fractures is the thoracic spine. However, bone mineral density (BMD) measurements at the hip are used to…
  • Abstract Number: 0650 • ACR Convergence 2020

    Risk of Vertebral Fractures at Lateral Chest Radiographies in Patients with Gout

    Marco Ferrández-Jiménez1, Irene Calabuig2, Maria Luisa Peral2, Miguel Gómez-Garberí1 and Mariano Andrés2, 1Universidad Miguel Hernández de Elche, Alicante, Spain, 2Hospital General Universitario de Alicante-ISABIAL and Universidad Miguel Hernández de Elche, Alicante, Spain

    Background/Purpose: Osteoporosis causes significant morbidity and mortality through the development of fragility fractures, including vertebral fractures (VF). Patients with gout may show an increased risk…
  • Abstract Number: 0023 • ACR Convergence 2020

    Hypophosphatasia May Be Misdiagnosed as Fibromyalgia: A Single Center Experience

    Patil Injean1, Sandy Lee1 and Christina Downey1, 1Loma Linda University Medical Center, Redlands, CA

    Background/Purpose: Hypophosphatasia (HPP) is a rare disease characterized by incomplete or defective bone mineralization due to a mutation in the alkaline phosphatase gene (ALPL).  Given…
  • Abstract Number: 0926 • ACR Convergence 2020

    Risk Factors for Fractures and Osteoporosis Among Patients with Systemic Sclerosis in a United States Cohort

    Sina Famenini1, Jamie Perin2, Kristin Wipfler3, Kaleb Michaud4 and Zsuzsanna McMahan5, 1Johns Hopkins School of Medicine, Baltimore, MD, 2JHUSPH, Baltimore, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Johns Hopkins University, Baltimore

    Background/Purpose:Systemic sclerosis (SSc) is associated with several risk factors for osteoporosis and fractures due to malabsorption or malnutrition, physical disability, chronic inflammation, and use of…
  • Abstract Number: 0090 • ACR Convergence 2020

    110 Patients with Monoclonal Gammopathy of Undetermined Significance (MGUS) in a Rheumatology Disease Unit: Fracture, Neuropathy, and Pernicious Anemia Are Clues to Recognition

    Michael Lovy1 and Andrew Dulalia1, 1Desert Oasis Healthcare, Palm Springs, CA

    Background/Purpose: Monoclonal gammopathy of undetermined significance (MGUS) has been associated with osteoporosis, neuropathy, pernicious anemia, and low vitamin B12, and may precede multiple myeloma and…
  • Abstract Number: 1005 • ACR Convergence 2020

    Risk of Non-vertebral Fractures Among Rheumatoid Arthritis Patients Treated with Biologic or Targeted-Synthetic DMARDs: A Multi-Database Comparative Safety Study

    Ajinkya Pawar1, Rishi Desai1, Mengdong He1, Lily Bessette1 and Seoyoung Kim2, 1Brigham and Women's hospital, Boston, 2Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Rheumatoid arthritis (RA) increases risk of osteoporosis and fractures. However, limited head-to-head comparative data exists on the risk of non-vertebral osteoporotic fractures (NVFs) among…
  • Abstract Number: 0091 • ACR Convergence 2020

    Helicobacter Pylori Infection, Autoimmune Disease and Paraproteinemia Influence the Presentation of a Cohort of 150 Pernicious Anemia Patients Diagnosed in a Rheumatology Clinic

    Michael Lovy1, Norma Daniela Aguirre Vega1 and Crystal Escobar1, 1Desert Oasis Healthcare, Palm Springs, CA

    Background/Purpose: The most familiar presentation of pernicious anemia is an elderly Northern European woman with hematologic and neurologic manifestations.  More recently the influence of Helicobacter…
  • Abstract Number: 1134 • ACR Convergence 2020

    Prevalence of Frailty and Associated Factors in a National Observational Cohort of Rheumatic Diseases

    Katherine Wysham1, Joshua Baker2, Kristin Wipfler3, Sarah Lieber4, Sebastian Sattui4, Patricia Katz5 and Kaleb Michaud6, 1VA Puget Sound/University of Washington, Seattle, WA, 2University of Pennsylvania, Philadelphia, PA, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4Hospital for Special Surgery, New York, NY, 5University of California, San Francisco, Novato, CA, 6University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Frailty is associated with poor health outcomes in the general population, and recent studies have highlighted its importance in rheumatic musculoskeletal diseases (RMDs). Prior…
  • Abstract Number: 0102 • ACR Convergence 2020

    Bone Health in Patients with Psoriatic Arthritis in the National Swiss Cohort: A Cross-sectional Study

    Diana Camelia Dan1, Youssef Ibrahimy2, Berengere Aubry-Rozier3 and Daniel Aeberli4, 1Lausanne University Hospital, Lausanne, Switzerland, 2University of Lausanne, Lausanne, Switzerland, 3Hôpital orthopédique, Lausanne, Switzerland, 4University Hospital of Bern, Bern, Switzerland

    Background/Purpose: There is much controversy surrounding the loss of bone mass in patients with psoriasis arthritis (PsA). We wanted to evaluate the prevalence of osteoporosis…
  • Abstract Number: 1897 • ACR Convergence 2020

    Trends in Hospitalizations for Vertebral Compression Fractures in Ankylosing Spondylitis: Data from the National Inpatient Sample 2001-2014

    Anish Paudel1, Rashmi Dhital2, Dilli Poudel3, Anthony Donato1 and Paras Karmacharya4, 1Reading Hospital and Medical Center, West Reading, PA, 2Reading Hospital and Medical Center, West Reading, 3University of Pennsylvania, Philadelphia, PA, 4Mayo Clinic, Rochester MN, ROCHESTER, MN

    Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease predominantly affecting the spine, leading to syndesmophyte formation, ankylosis, and osteoporosis. These factors have been associated…
  • Abstract Number: 0103 • ACR Convergence 2020

    The Association of Methotrexate, Sulfasalazine and Hydroxychloroquine Use with Incident Fractures in Postmenopausal Women with Rheumatoid Arthritis: Findings from the Women’s Health Initiative

    Rachel Elam1, Sandeepkumar Gupta2, Omar Tolaymat2, Sowmya Vasan3, Carolyn Crandall4, Jean Wactawski-Wende5, Karen Johnson6 and Laura Carbone2, 1Augusta University, Evans, GA, 2Augusta University, Augusta, GA, 3WHI, Seattle, WA, 4UCLA, Los Angeles, CA, 5University of Buffalo, Buffalo, NY, 6University of Tennessee Health Sciences Center, Memphis, TN

    Background/Purpose: This study was conducted to evaluate the extent to which disease modifying antirheumatic medications (DMARDs) used as part of triple therapy for treatment of…
  • Abstract Number: 1974 • ACR Convergence 2020

    Validation of a Deep Learning Based Algorithm to Diagnose Vertebral Compression Fractures

    John Page1, Franklin Moser2, Marcel Maya3, Ravi Prasad3 and Barry Pressman2, 1Amgen, Inc, Thousand Oaks, CA, 2Cedars-Sinai Medical Center, Los Angeles, CA, 3Cedars-Sinai Medical Center, Los Angeles

    Background/Purpose: Vertebral Compression Fractures are common in patients above age 50, but are often undiagnosed.  Patients with one VCF are at higher risk of other…
  • Abstract Number: 0116 • ACR Convergence 2020

    The in Vitro 3D Fracture Gap Model: A Tool for Preclinical Testing

    Moritz Pfeiffenberger1, Alexandra Damerau1, Paula Hoff2, Annemarie Lang1, Frank Buttgereit3 and Timo Gaber1, 1Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Rheumatology and Clinical Immunology, Berlin, Germany, 2Endokrinologikum Berlin, Rheumatologie, Berlin, Germany, 3Charité University Medicine, Berlin, Germany

    Background/Purpose: Approximately 10% of fractures lead to significant fracture healing disorders. Of note, especially immunosuppressed patients with ongoing inflammation show difficulties in the correct course…
  • Abstract Number: 1976 • ACR Convergence 2020

    High Disease Activity Is Associated with Incident Osteoporotic Fractures Among Veterans with Rheumatoid Arthritis

    Katherine Wysham1, Ted Mikuls2, Bryant England2, Dolores Shoback3, Patricia Katz4, Jose Garcia1, Brian Sauer5, Beth Wallace6, John Richards7, Paul Monach8, Grant Cannon9 and Joshua Baker10, 1VA Puget Sound/University of Washington, Seattle, WA, 2University of Nebraska Medical Center, Omaha, NE, 3San Francisco VA/University of California, San Francisco, San Francisco, CA, 4University of California, San Francisco, Novato, CA, 5University of Utah, Omaha, NE, 6Michigan Medicine, VA Ann Arbor Healthcare System Center for Clinical Management Research, Ann Arbor, MI, 7Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, 8Brigham and Women's, Boston, 9Salt Lake City VA Medical Center and University of Utah, Salt Lake City, 10University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Rheumatoid arthritis (RA) is a risk factor for osteoporosis and fractures yet the disease specific contributions to osteoporotic fractures (OFX) are not well understood.…
  • Abstract Number: 0118 • ACR Convergence 2020

    Indicators of Effectiveness After 6 Years of Follow-up in a Fracture Liaison Service

    Antonio Naranjo Hernandez1, Amparo Molina2, Cristina Sepúlveda2, Francisco Rubiño3, Adrian Quevedo3 and Soledad Ojeda3, 1Hospital Universitario Dr Negrin, Las Palmas, Canarias, Spain, 2Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas, Spain, 3Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas

    Background/Purpose: Data on the effectiveness of FLS in the medium and long term are needed. The objetive of this study was to analyze the indicators of…
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