Abstracts tagged "fibromyalgia"

Abstract Number: 2299 • 2015 ACR/ARHP Annual Meeting
Association Between Catechol-O-Methyl Transferase Gene Polymorphisms and Fibromyalgia in a Korean Population: A Case-Control Study
Yi-Rang Yim¹, Dong-Jin Park², Seong-Ho Kim³, Seong-Su Nah⁴, Ji Hyun Lee⁵, Seong-Kyu Kim⁶, Yeon-Ah Lee⁷, Seung-Jae Hong⁸, Hyun-Sook Kim⁹, Hye-Soon Lee¹⁰, Hyoun-Ah Kim¹¹, Chung-Il Joung¹², Sang-Hyon Kim¹³ and Shin-Seok Lee¹, ¹Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ³Inje University Haeundae Paik Hospital, Busan, South Korea, ⁴Soonchunhyang University, College of Medicine, Cheonan, South Korea, ⁵Internal Medicine, Maryknoll Medical Center, Busan, South Korea, ⁶Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, South Korea, ⁸Dept. of Rheumatology, #1 Hoeg, KyungHee University Medical Center, SEOUL, South Korea, ⁹Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea, ¹⁰Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ¹¹Ajou University Hospital, Suwon, South Korea, ¹²Internal Medicine, Konyang University Medical School, Daejeon, South Korea, ¹³Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: Although polymorphisms of the catechol-O-methyl transferase (COMT) gene have been implicated in altered pain sensitivity, results concerning the association between COMT gene polymorphisms and…
Abstract Number: 3091 • 2015 ACR/ARHP Annual Meeting
A Randomized, Controlled Trial of Pregabalin in Adolescent Patients (12-17 years) with Fibromyalgia
Lesley Arnold¹, Lucinda Bateman², Kenneth N. Schikler³, Tahira Khan⁴, Lynne Pauer⁴, Pritha Bhadra Brown⁵, Marci L. Chew⁴, Andrew Clair⁵ and Joseph Scavone⁴, ¹University of Cincinnati, Cincinnati, OH, ²Bateman Horne Center, Salt Lake City, UT, ³Pediatrics, University of Louisville, Louisville, KY, ⁴Pfizer Inc, Groton, CT, ⁵Pfizer Inc., New York, NY
Background/Purpose: :Fibromyalgia (FM) is characterized by chronic widespread pain, sleep disturbance, and fatigue. Pregabalin is approved in the US in adults for the management of…
Abstract Number: 76 • 2015 ACR/ARHP Annual Meeting
Evaluating Weather’s Effect on Fibromyalgia Patients Using the Revised Fibromyalgia Impact Questionnaire and the Brief Pain Inventory
Daniel Kim¹, Ruth Chan¹, Marcal Plans² and Kevin Hackshaw¹, ¹Rheumatology & Immunology, Ohio State University, Columbus, OH, ²Food Science and Technology Department, Ohio State University, Columbus, OH
Background/Purpose: The objective of this study was to evaluate whether weather had an affect on fibromyalgia symptoms as measured by the Revised Fibromyalgia Impact Questionnaire…
Abstract Number: 2300 • 2015 ACR/ARHP Annual Meeting
Polymorphisms of Transient Receptor Potential Vanilloid (TRPV) 2 and TRPV3 Gene Polymorphisms Were Associated with Fibromyalgia in a Korean Population
Yi-Rang Yim¹, Dong-Jin Park², Seong-Ho Kim³, Seong-Su Nah⁴, Ji Hyun Lee⁵, Seong-Kyu Kim⁶, Yeon-Ah Lee⁷, Seung-Jae Hong⁸, Hyun-Sook Kim^9,10, Hye-Soon Lee¹¹, Hyoun-Ah Kim¹², Chung-Il Joung¹³, Sang-Hyon Kim¹⁴ and Shin-Seok Lee¹, ¹Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ³Inje University Haeundae Paik Hospital, Busan, South Korea, ⁴Soonchunhyang University, College of Medicine, Cheonan, South Korea, ⁵Internal Medicine, Maryknoll Medical Center, Busan, South Korea, ⁶Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, School of Medicine, Kyung Hee University, Seoul, South Korea, ⁸Dept. of Rheumatology, #1 Hoeg, KyungHee University Medical Center, SEOUL, South Korea, ⁹Internal Medicine, College of Medicine, Chosun University, Gwangju, South Korea, ¹⁰Division of Rheumatology, Department of Internal Medicine, Soonchunhyang University of Korea, Seoul, South Korea, ¹¹Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ¹²Ajou University Hospital, Suwon, South Korea, ¹³Internal Medicine, Konyang University Medical School, Daejeon, South Korea, ¹⁴Division of Rheumatology, Department of Internal Medicine, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: Fibromyalgia (FM) is a chronic pain syndrome characterized by lowered pain thresholds and other FM-related symptoms such as fatigue, anxiety and depression. Recent studies…
Abstract Number: 78 • 2015 ACR/ARHP Annual Meeting
Exploratory Analysis of Somatic Symptoms in Fibromyalgia By Multidimensional Scaling and Latent Class Analysis
Marco Antivalle¹, Michele Battellino¹, Alberto Batticciotto¹, MariaChiara Ditto¹, Alessandra Mutti¹, Valentina Varisco¹, Federica Rigamonti¹, Fabiola Atzeni¹ and Piercarlo Sarzi-Puttini², ¹Rheumatology, L. Sacco University Hospital, Milano, Italy, ²Rheumatology Unit, L. Sacco University Hospital, Milano, Italy
Background/Purpose: Attempts to individuate subsets of fibromyalgia patients based on the aggregation of different symptoms have so far produced conflicting results. The 2010 preliminary diagnostic…
Abstract Number: 2301 • 2015 ACR/ARHP Annual Meeting
Facing Fibromyalgia; How Patients Describe Their Symptoms Based on a Retrospective Evaluation of a Patient Survey and Vitality Assessment in Clinical Trials
Andrew Clair¹, Lynne Pauer² and Elizabeth Masters¹, ¹Pfizer Inc., New York, NY, ²Pfizer Inc, New London, CT
Background/Purpose: Fibromyalgia (FM) is a common chronic widespread pain disorder with comorbid symptoms of fatigue, sleep disturbance, cognitive dysfunction and depression. It is believed to…
Abstract Number: 80 • 2015 ACR/ARHP Annual Meeting
Paresthesias in Fibromyalgia Patients
Robert S. Katz¹, Lauren Kwan², Kelli Davis² and Jessica L. Polyak², ¹Rush University Medical Center, Chicago, IL, ²Rheumatology Associates S.C., Chicago, IL
Background/Purpose: Paresthesias are common in patients with fibromyalgia. We evaluated the symptoms of numbness and tingling in fibromyalgia patients and rheumatic disease controls without…
Abstract Number: 2302 • 2015 ACR/ARHP Annual Meeting
The Impact of Prior Fibromyalgia Treatment on the Response to Pregabalin in Fibromyalgia Clinical Trials
Lynne Pauer¹, Andrew Clair², Pritha Bhadra Brown², Marie Ortiz² and Joseph Scavone¹, ¹Pfizer Inc, Groton, CT, ²Pfizer Inc., New York, NY
Background/Purpose: Fibromyalgia (FM) is a chronic, widespread pain disorder for which Lyrica is an approved treatment. Antidepressants, gabapentin, muscle relaxants, and opioids are frequently used…
Abstract Number: 84 • 2015 ACR/ARHP Annual Meeting
Sexual Dimorphism in the Association Between Multi-Site Pain and Other Fibromyalgia Features: an Analysis of Data from Three UK Population-Based Studies
Linda E. Dean¹, Lesley Arnold², Robert Bennett³, Leslie J. Crofford⁴, Don Goldenberg⁵, Elisa Flüß¹, Daniel J. Clauw⁶, Mary-Ann Fitzcharles⁷, Eduardo Paiva⁸, Roland Staud⁹ and Gary J. Macfarlane¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²University of Cincinnati, Cincinnati, OH, ³SN-Office of Research & Development, Oregon Health & Science Univ, Portland, OR, ⁴Medicine, Vanderbilt University, Nashville, TN, ⁵Newton-Wellesley Hospital, Newton, MA, ⁶Anesthesiology, University of Michigan, Ann Arbor, MI, ⁷MGH, Montreal, QC, Canada, ⁸Rheumatology, Universidade Federal do Parana, Curitiba Parana, Brazil, ⁹University of Florida, Gainesville, FL
Background/Purpose: The 2011 modification of the preliminary 2010 American College of Rheumatology criteria for fibromyalgia require the self-report of multi-site pain in addition to a…
Abstract Number: 2305 • 2015 ACR/ARHP Annual Meeting
Relationship Between Anxiety, Depression, Sleep, Fibromyalgia and BMI in Patients with Rheumatic Disease
Shazia Bég¹ and Ali Ahmad², ¹Rheumatology, University of Central Florida, Orlando, FL, ²University of Central Florida, Orlando, FL
Background/Purpose: Patients with rheumatic diseases often have comorbidities that complicate their psychological well-being and affect prognosis. In this study, we looked at 216 patients with…
Abstract Number: 119 • 2015 ACR/ARHP Annual Meeting
Triage in Chronic Rheumatic Diseases: Quantitative Physician Estimates for Inflammation (Reversible), Damage (Irreversible), and Distress in Patients with Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia Seen in Usual Care
Isabel Castrejón¹, Kathryn A. Gibson², Ruchi Jain¹, Annie Huang¹, Joel A. Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Liverpool, Australia, ³Rush University Medical Center, Chicago, IL
Background/Purpose: A physician estimate of a patient’s global status (DOCGL) often is most often the most efficient of all 7 rheumatoid arthritis (RA) core data…
Abstract Number: 2307 • 2015 ACR/ARHP Annual Meeting
Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL)
Harvey Moldofsky¹, R Michael Gendreau², Daniel J. Clauw³, Judith Gendreau⁴, Benjamin Vaughn⁵, Bruce Daugherty⁴, Amy Forst⁶, Gregory Sullivan⁷ and Seth Lederman⁸, ¹Ctr for Sleep & Chronobiology, Centre for Sleep/Chronobiology, Toronto, ON, Canada, ²Gendreau Consulting LLC, Poway, CA, ³Anesthesiology, University of Michigan, Ann Arbor, MI, ⁴Tonix Pharmaceuticals, New York, NY, ⁵Statistics, Rho, Chapel Hill, NC, ⁶Clinical Development, Tonix Pharmaceuticals, San Jose, CA, ⁷Clinical Development, Tonix Pharmaceuticals, NEW YORK, NY, ⁸Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: The importance of nonrestorative sleep in the pathophysiology of fibromyalgia (FM) suggests that treatments that improve sleep quality would address global symptoms. TNX-102 SL1a…
Abstract Number: 154 • 2015 ACR/ARHP Annual Meeting
Clinical Features of Fibromyalgia in Patients with Rheumatoid Arthritis Predict Lower Power Doppler Scores on Ultrasound
Aneela Mian¹, Khaldoun Chaabo², Julekha Wajed³, Bruce W. Kirkham⁴ and Toby Garrood⁵, ¹Academic Rheumatology, King's College London, London, United Kingdom, ²Rheumatology, Guy's and St Thomas NHS Trust, London, United Kingdom, ³Rheumatology, Guys' and St Thomas' NHS Trust, London, United Kingdom, ⁴Rheumatology, Guy's and St. Thomas' Foundation Hospital NHS Trust, London, United Kingdom, ⁵Rheumatology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom
Background/Purpose: Up to 20% of patients with RA have coexisting fibromyalgia(FM). This can make treatment decisions challenging in clinical practice as disease activity scores can…
Abstract Number: 2308 • 2015 ACR/ARHP Annual Meeting
Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL)
R Michael Gendreau¹, Daniel J. Clauw², Judith Gendreau³, Bruce Daugherty³ and Seth Lederman⁴, ¹Gendreau Consulting LLC, Poway, CA, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Tonix Pharmaceuticals, New York, NY, ⁴Research and Development, Tonix Pharmaceuticals, Inc., New York, NY
Background/Purpose: Fibromyalgia (FM) is characterized by symptoms that include widespread pain and sleep disruption. Clinical studies that rely on patient self-reported outcome measures such as pain…
Abstract Number: 1090 • 2015 ACR/ARHP Annual Meeting
Characteristics and Trajectories of Child Pain, Function, and Psychological Outcomes Associated with Conversion Disorder in Intensive Interdisciplinary Pediatric Pain Rehabilitation
Cara Hoffart¹ and Dustin Wallace², ¹Rheumatology and Integrative Pain Management, Children's Mercy Hospital, Kansas City, MO, ²Integrative Pain Management and Developmental and Behavioral, Children's Mercy Hospital, Kansas City, MO
Background/Purpose: Given the degree of compromise in quality of life, there is a critical need to identify the natural history of pain and disability in…

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