Abstracts tagged "Fatigue"

Abstract Number: 0462 • ACR Convergence 2021
Remotely Delivered Cognitive Behavioural and Personalised Exercise Interventions Reduce Fatigue Severity and Impact in Inflammatory Rheumatic Diseases: Results from a Multi-centre Randomised Controlled Parallel Group Trial
Eva-Maria Bachmair¹, Kathryn Martin Remmes¹, Lorna Aucott¹, Emma Dures², Richard Emsley³, Stuart Gray⁴, Elizabeth Kidd⁵, Vinod Kumar⁶, Karina Lovell⁷, Graeme MacLennan¹, Paul McNamee¹, John Norrie⁸, Lorna Paul⁹, Jon Packham¹⁰, Stuart Ralston¹¹, Stefan Siebert⁴, Alison Wearden⁷, Gary Macfarlane¹² and Neil Basu⁴, ¹University of Aberdeen, Aberdeen, United Kingdom, ²University of West of England, Bristol, United Kingdom, ³King's College London, London, United Kingdom, ⁴University of Glasgow, Glasgow, United Kingdom, ⁵Newcastle Hospitals NHS Foundation Trust, Newcastle, United Kingdom, ⁶NHS Tayside, Dundee, United Kingdom, ⁷University of Manchester, Manchester, United Kingdom, ⁸Usher Institute – University of Edinburgh, Edinburgh, United Kingdom, ⁹Glasgow Caledonian University, Glasgow, Scotland, United Kingdom, ¹⁰Midlands Partnership NHS Foundation Trust, Stoke-on-Trent, United Kingdom, ¹¹University of Edinburgh, Edinburgh, Scotland, United Kingdom, ¹²Epidemiology Group, Institute of Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom
Background/Purpose: Inflammatory rheumatic disease (IRD) related fatigue is pervasive and disabling, even in otherwise stable disease. Although cognitive-behavioural approaches (CBAs) and personalised exercise programmes (PEP)…
Abstract Number: 0655 • ACR Convergence 2021
Depression and Fatigue: Two Forgotten Associated Comorbidities in Patients with Rheumatoid Arthritis
Rosa Morlà¹, Beatriz Frade-Sosa², Núria Sapena³, Roberto Gumucio², Raimon Sanmarti² and Jose A Gomez-Puerta², ¹Hospital Universitari Clinic de Barcelona, Barcelona, Spain, ²Hospital Clínic de Barcelona, Barcelona, Spain, ³Rheumatology Department, Hospital Clínic, Barcelona, Spain
Background/Purpose: Rheumatoid arthritis (RA) is frequently associated with different comorbidities. Depression and fatigue are common in RA patients with a prevalence of 17-39-%(1) and 40%(2)…
Abstract Number: 0717 • ACR Convergence 2021
Association of Fatigue with Disease Activity in Myositis
Tissa Bijoy George¹, Anjana Chandrasekhara Pillai², Siamak Moghadam-Kia³, Nicole Neiman⁴, Dana Ascherman³, Chester Oddis³, Dianxu Ren⁴ and Rohit Aggarwal³, ¹UPMC McKeesport, Monroeville, PA, ²UPMC, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA
Background/Purpose: The Idiopathic inflammatory myopathies are a heterogeneous group of rare systemic autoimmune diseases with muscle as the primary target. Fatigue is one of the…
Abstract Number: 0854 • ACR Convergence 2021
Confirmatory Factor Analysis of the Fatigue Assessment Instrument and Fatigue Severity Scale in Systemic Sclerosis
Alyssa Choi¹, Chelsea Rapoport², Erin Merz³, Marka Lyons⁴, Maureen Mayes⁵, Shervin Assassi⁶ and Vanessa Malcarne⁷, ¹SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, ²SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology, La Jolla, CA, ³Department of Psychology, California State University, Dominguez Hills, Carson, CA, ⁴Division of Rheumatology, University of Texas McGovern Medical School at Houston, Houston, TX, ⁵Division of Rheumatology and Clinical Immunogenetics, University of Texas McGovern Medical School, Houston, TX, ⁶University of Texas McGovern Medical School at Houston, Houston, TX, ⁷SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology; Department of Psychology, San Diego State University, San Diego, CA
Background/Purpose: Fatigue is a prevalent, debilitating symptom across chronic diseases that is difficult to treat and negatively impacts patients' quality of life. Patients with rheumatologic…
Abstract Number: 0860 • ACR Convergence 2021
Associations Between Tricarboxylic Acid Cycle Plasma Metabolites and Fatigue Phenotypes in Black Females with Systemic Lupus Erythematosus: An Untargeted Metabolomics Analysis
Laura Kimble¹, Arezou Khosroshahi¹, Glenna Brewster¹, Nicole Carlson¹, Ronald Eldridge¹ and Elizabeth Corwin², ¹Emory University, Atlanta, GA, ²Columbia University, New York, NY
Background/Purpose: Systemic lupus erythematosus (SLE) occurs predominantly in women and Black women have disproportionately poorer health outcomes across the trajectory of their disease compared to…
Abstract Number: 1150 • ACR Convergence 2021
Use of Energy Conversation Strategies as a Result of the Fatigue Management Education for Individuals with Systemic Sclerosis (FAME-iSS)
Janet Poole¹, Deirdre Connolly² and Kristine Carandang³, ¹University of New Mexico, Albuquerque, NM, ²Trinity Centre for Health Sciences, Dublin, Ireland, ³Independent, San Diego, CA
Background/Purpose: Fatigue remains an understudied symptom of systemic sclerosis (SSc). For other diagnoses, increasing the use of energy conservation strategies, especially pacing. has been associated…
Abstract Number: 1235 • ACR Convergence 2021
Treatment Effect of Baricitinib on Fatigue: Mediation Analysis Results from Two Phase 3 Trials
Bruno Fautrel¹, Bochao Jia², Jianmin Wu³, Ju Ji², Julie Birt², Ewa Haladyj² and Tsutomu Takeuchi⁴, ¹Pitié Salpêtrière Hospital, APHP, Sorbonne Université, Paris, France, ²Eli Lilly and Company, Indianapolis, IN, ³Eli Lilly and Company, Indianaplolis, IN, ⁴Div. Rheumatology, Keio University, Tokyo, Japan
Background/Purpose: Fatigue is very common in rheumatoid arthritis (RA) and impairs patient quality of life. Baricitinib (BARI) improved fatigue, pain and other patient-reported outcomes (PROs)…
Abstract Number: 1273 • ACR Convergence 2021
A 12-week Aerobic Exercise Training Program in Women with Systemic Lupus Erythematosus (SLE) Improves Fatigue, Mitochondrial Dysfunction and Associated Interferon Gene Signature
Sarfaraz Hasni¹, Marquis Chapman², Rebekah Feng¹, Anam Ahmad¹, Sarthak Gupta³, Mohammad Naqi¹, Adam Munday¹, Shajia Lu¹, Massimo Gadina², Zerai Manna¹, Xiaobai Li⁴, Yinghui Shi¹, Kalyani Mishra-Thakur¹, Michael Davis⁵, Jun Chu³, Elaine Poncio⁶, Yenealem Temesgen-Oyelakin⁷, Jonathan Martinez¹, Zoe Morris¹, Isabel Ochoa⁶, Shuichiro Nakabo⁸, Bart Drinkard¹, Gayle McCrossin¹, Marybeth Stockman¹, Mariana Kaplan¹, Leorey Saligan¹, Randall Keyser⁹, Leighton Chan¹ and Lisa Chin¹, ¹National Institutes of Health, Bethesda, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, ³National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, ⁴Clinical Center, National Institutes of Health, Bethesda, MD, ⁵NIAMS, Bethesda, MD, ⁶NIH/NIAMS, Bethesda, MD, ⁷National Institutes of Health (NIH), Bethesda, MD, ⁸NIAMS/NIH, Bethesda, MD, ⁹George Mason University, Bethesda
Background/Purpose: Fatigue in SLE patients is ubiquitous and is reported as one of the most debilitating symptoms. Yet mechanisms underlying the pathophysiology of SLE-related fatigue…
Abstract Number: 0118 • ACR Convergence 2021
Multidimensional Phenotypes of Sleep Quality Using the Pittsburg Quality Sleep Index and Associations Among Sleep Dimensions and Symptoms in Women Diagnosed with Fibromyalgia
Victoria Menzies, Debra Lynch Kelly and Miichael Weaver, University of Florida, Gainesville, FL
Background/Purpose: There are over 10 million people in the United States suffering with fibromyalgia syndrome (FMS). Individuals with FMS typically report multiple concurrent symptoms including…
Abstract Number: 1371 • ACR Convergence 2021
Symptom Management in Systemic Sclerosis: A Pilot Study of a Web-based Intervention Using Peer-Health Coaches
Susan Murphy¹, Yen Chen², Mary Alore², Sheri Hicks² and Dinesh Khanna², ¹University of Michigan, Grosse Ile, MI, ²University of Michigan, Ann Arbor, MI
Background/Purpose: People with systemic sclerosis (SSc) have a high burden of chronic symptoms that have dramatic effects on function and quality of life. Fatigue, along…
Abstract Number: 0119 • ACR Convergence 2021
Worsened Depression but Improved Fatigue Were the Main Impacts of Severe Lockdown in Non- COVID Infected Australian Fibromyalgia Patients
Benjamin Worcester¹, Emma Guymer² and Geoffrey Littlejohn², ¹Monash Health, Melbourne, Australia, ²Monash University, Melbourne, Australia
Background/Purpose: To gauge the impact of severe COVID-19 related lockdown restrictions on the mental and physical wellbeing of Australian fibromyalgia patients and their recovery following…
Abstract Number: 1605 • ACR Convergence 2021
Health Related Quality of Life in Rheumatology Outpatients with COVID-19 from New York City over the Course of the Pandemic
Lisa Mandl¹, Jonah Levine¹, Vivian Bykerk² and Medha Barbhaiya¹, ¹Hospital for Special Surgery, New York, NY, ²Division of Rheumatology, Hospital for Special Surgery, New York City, NY
Background/Purpose: The impact of the COVID-19 pandemic on the mental and physical well-being of patients with systemic rheumatic diseases (SRDs) remains to be quantified. We…
Abstract Number: 0229 • ACR Convergence 2021
The Effects of Self-efficacy on Fatigue and Pain Interference in Black Women with Systemic Lupus Erythematosus: The Role of Depression, Age, and Education
Cristina Drenkard¹, Kirk Easley¹, Gaobin Bao¹, Charmayne Dunlop-Thomas¹, Teresa Brady² and S Sam Lim³, ¹Emory University, Atlanta, GA, ²Clarity Consulting and Communications, Atlanta, GA, ³Department of Medicine, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA
Background/Purpose: Fatigue and pain are pervasive symptoms that cause escalating distress in patients with SLE, particularly among Black women and other high-risk groups. While these…
Abstract Number: 1699 • ACR Convergence 2021
The “ITIS” Diet Improves Fatigue in Patients with Rheumatoid Arthritis and Is Associated with Changes in Metabolome and Fecal Microbiome
Roxana Coras¹, Cameron Martino¹, Julia Gauglitz¹, Alan Jarmusch¹, Anupriya Tripathi¹, Francesca Cedola², Marta Fernandez-Bustamante¹, Meritxall Agustín-Perez¹, Maram Alharthi¹, Susan Lee¹, Abha Singh¹, Soo In Choi¹, Tania Rivera¹, Katherine Nguyen³, Tatyana Shekhtman¹, Tiffany Holt¹, Shahrokh Golshan¹, Rob Knight¹, Pieter C Dorrestein¹ and Monica Guma¹, ¹University of California San Diego, La Jolla, CA, ²University of California San Diego, Rome, CA, Italy, ³University of California San Diego, San Diego, CA
Background/Purpose: Fatigue is common symptom in rheumatoid arthritis (RA), associated with decreased quality of life and productivity. Fatigue mechanisms have not been well studied, hence,…
Abstract Number: 0230 • ACR Convergence 2021
Fatigue and Inflammation in Rheumatoid Arthritis Are Already Disconnected Before Clinical Arthritis Develops
Sarah J.H. Khidir¹, Annette H.M van der Helm-van Mil¹ and Elise van Mulligen², ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Fatigue is disabling and common in Rheumatoid Arthritis (RA); the causation of fatigue in RA is multidimensional and only partially explained by inflammation. The…

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