Abstracts tagged "Fatigue"

Abstract Number: 1033 • ACR Convergence 2022
Risk of Mood Disorders in SpA Patients and Correlations with Disease Activity, Quality of Life and Working Ability: Analysis of a Monocentric Cohort
Cosimo Cigolini¹, Federico Fattorini¹, Linda Carli², Andrea Delle Sedie³, Marta Mosca² and Gabriele Marchetti⁴, ¹Rheumatology Unit, University of Pisa, Pisa, Toscana, Italy, ²Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, PISA, Italy, ³University of Pisa, Pisa, Pisa, Italy, ⁴University of Pisa, Pisa, Toscana, Italy
Background/Purpose: Spondyloarthropathies (SpA) are chronic inflammatory arthritides, characterized by both peripheral and axial skeletal involvement and some typical extra-articular marks; they tend to associate with…
Abstract Number: 1220 • ACR Convergence 2022
Autonomic Dysfunction in Sjogren’s Disease
Ardy Fenando¹, Jordan Estes¹, Maha Mohamad¹, Sareena Shah², John Lee², Duaa Jabari¹, Joshua Baker³ and Ghaith Noaiseh¹, ¹University of Kansas Medical Center, Kansas City, KS, ²University of Missouri-Kansas City, Kansas City, MO, ³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Sjogren's Disease (SjD) is a heterogenous autoimmune disease associated with debilitating symptoms. Autonomic dysfunction (AD) is common in SjD and may contribute to symptom…
Abstract Number: 1270 • ACR Convergence 2022
MDHAQ/RAPID3 Is a Feasible Tool to Estimate High Comorbid Fatigue and Residual Fatigue in Rheumatoid Arthritis Patients
Rosa M. Morlà¹, Beatriz Frade-Sosa¹, Nuria Sapena¹, Jose A Gomez-Puerta¹, Raimon Sanmarti¹ and Theodore Pincus², ¹Hospital Clínic de Barcelona, Barcelona, Spain, ²Rush University Medical Center, Chicago, IL
Background/Purpose: Fatigue is a major symptom for rheumatoid arthritis (RA) patients with a high prevalence (40%-70%)1 measured by different validated questionnaires and scales. A 0-10…
Abstract Number: 1344 • ACR Convergence 2022
Patient-reported Outcomes in Lupus Low Disease Activity State: Impact of Fatigue
Rodrigo De Moura Rodrigues, Alexandre Moura dos Santos, Daniel Sampaio Cardoso, Emily Figueiredo Neves Yuki, Danieli Castro Oliveira de Andrade, Sandra Gofinet Pasoto, Eduardo Ferreira Borba Neto, Eloisa Silva Dutra de Oliveira Bonfa and Luciana Seguro, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Patient Reported Outcomes (PROs) can be assessed by self-administered questionnaires and can lead to better decision-making by physicians. The aim of this study was…
Abstract Number: 1458 • ACR Convergence 2022
Systemic Lupus Erythematosus (SLE) Patients with Cognitive Impairment Experience More Fatigue Compared to Patients Without Impairment
Delansie Lawrence¹, Jiandong Su¹, Andrea Knight², Kathleen Bingham³, Mahta Kakvan¹, Maria Carmela Tartaglia⁴, Leslet Ruttan⁵, Joan Wither⁶, May Choi⁷, Simone Appenzeller⁸, Nicole Anderson¹, Dennisse Bonilla¹, Patricia Katz⁹, Dorcas Beaton¹⁰, Robin Green⁵, Zahi Touma¹ and Michelle Barraclough¹¹, ¹Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, ²The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, ³Centre for Mental Health, University Health Network; Department of Psychiatry, University of Toronto, Toronto, ON, Canada, ⁴University of Toronto Krembil Neurosciences Centre, Toronto, ON, Canada, ⁵University Health Network-Toronto Rehabilitation Institute, Toronto, ON, Canada, ⁶Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada, ⁷Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, ⁸Unicamp, Campinas, São Paulo, Brazil, ⁹UCSF, San Rafael, CA, ¹⁰Institute for Work & Health, Toronto, ON, Canada, ¹¹Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, University of Toronto, Centre for Epidemiology Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Toronto, ON, Canada
Background/Purpose: Cognitive impairment (CI) is highly prevalent in patients with systemic lupus erythematosus (SLE). Objective prevalence rates are reported as 38% [range: 20% to 80%]…
Abstract Number: 1847 • ACR Convergence 2022
Differences in Key Patient-reported Outcome Domains Identified by the Patient Acceptable Symptom State in the Adult SAPHO and Chronic Nonbacterial Osteomyelitis Observational Study (The SAPHO-CNO Study)
Aleksander Lenert¹, Robyn Domsic², Karmela Kim Chan³, Melissa Oliver⁴, Jisna Paul⁵, Courtney Kremer⁶, Emma Leisinger¹, Svjetlana Dolovcak⁷, Sandy D. Hong⁸, Aruni Jayatilleke⁹, Petar Lenert⁷, T. Shawn Sato¹, Samir Shah¹⁰, Shima Yasin¹¹, Yongdong (Dan) Zhao¹², Daniel Solomon¹³, Jonathan Templin¹ and Polly Ferguson¹¹, ¹University of Iowa, Iowa City, IA, ²University of Pittsburgh, Pittsburgh, PA, ³Hospital for Special Surgery, New York, NY, ⁴Indiana University School of Medicine, Indianapolis, IN, ⁵Ohio State University Hospital, Dublin, OH, ⁶University of Iowa Stead Family Children's Hospital, Solna, IA, ⁷University of Iowa Hospitals and Clinics, Iowa City, IA, ⁸University of Iowa Stead Family Children's Hospital, Iowa City, IA, ⁹Temple University, PHILADELPHIA, PA, ¹⁰Tufts Medical Center, Boston, MA, ¹¹University of Iowa Carver College of Medicine, Iowa City, IA, ¹²University of Washington, Redmond, WA, ¹³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Incorporating patient perspectives of their disease state is needed for disease activity assessment in adults with SAPHO syndrome and chronic nonbacterial osteomyelitis (CNO). The…
Abstract Number: 1945 • ACR Convergence 2022
Determinants of Patient’s Global Assessment of Disease Severity and Predictors of Disease Course in Juvenile Fibromyalgia
Clara Malattia¹, Claudio Lavarello¹, Alessandra Alongi², Benedetta Mori², Anna Ronchetti³, Lino Nobili⁴, Lorenzo Chiarella⁵, Elena Pescio⁶, Angelo Ravelli⁷ and Marco Gattorno⁸, ¹Pediatric Clinic and Rheumatology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy,Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (DINOGMI) University of Genoa, Genova, Italy, ²Department of Pediatric Emergency, ARNAS Civico-Di Cristina-Benfratelli, Palermo, Italy, ³Physical Medicine and Rehabilitation Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁴Child Neuropsychiatry Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy,Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (DINOGMI) University of Genoa, Genova, Italy, ⁵Child Neuropsychiatry Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy,Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (DINOGMI) University of Genoa, Genova, ⁶Psychology Unit, IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁷Department of Neurosciences, Rehabilitation, Ophthalmology, Genetic and Maternal Infantile Sciences (DINOGMI) University of Genoa, Italy,Scientific Direction, IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁸Pediatric Clinic and Rheumatology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy
Background/Purpose: Juvenile Fibromyalgia Syndrome (JFS) is a disabling condition characterized by widespread musculoskeletal pain, fatigue and mood disturbances, which impact significantly on patients' quality of…
Abstract Number: 0230 • ACR Convergence 2021
Fatigue and Inflammation in Rheumatoid Arthritis Are Already Disconnected Before Clinical Arthritis Develops
Sarah J.H. Khidir¹, Annette H.M van der Helm-van Mil¹ and Elise van Mulligen², ¹Leiden University Medical Center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Fatigue is disabling and common in Rheumatoid Arthritis (RA); the causation of fatigue in RA is multidimensional and only partially explained by inflammation. The…
Abstract Number: 1807 • ACR Convergence 2021
Relationships Between Fatigue and Hemoglobin/C-Reactive Protein Levels and Associations Between Fatigue and Clinical Response in Patients with Active Psoriatic Arthritis: Results from Two Randomized Controlled Trials of Guselkumab (TREMFYA®)
Proton Rahman¹, Philip Mease², Atul Deodhar³, Laure Gossec⁴, Arthur Kavanaugh⁵, Soumya Chakravarty⁶, Alexa Kollmeier⁷, Yan Liu⁸, Xiwu Lin⁸, May Shawi⁹ and Chenglong Han⁸, ¹Department of Medicine, Eastern Health and Memorial University of Newfoundland, St John's, NL, Canada, ²Swedish Medical Center/Providence St. Joseph Health and University of Washington, Seattle, WA, ³Oregon Health & Science University, Portland, OR, ⁴Sorbonne Université; APHP, Rheumatology Department, Pitié-Salpêtrière Hospital, Paris, France, ⁵University of California San Diego, La Jolla, CA, ⁶Janssen Scientific Affairs, LLC and Drexel University College of Medicine, Horsham, PA, ⁷Janssen Research & Development, LLC, La Jolla, CA, ⁸Janssen Research & Development, LLC, Spring House, PA, ⁹Janssen Immunology Global Commercial Strategy Organization, Toronto, ON, Canada
Background/Purpose: Fatigue is a key patient (pt)-reported symptom of psoriatic arthritis (PsA).1,2 Utilizing data from the Phase 3 DISCOVER-1 (D1) and -2 (D2) studies, these…
Abstract Number: 0239 • ACR Convergence 2021
Work Disability Associated with Fatigue in Patients with Psoriatic Arthritis – a Retrospective Study Using Claims Data, 2009-2019
Elaine Husni¹, Steven Peterson², Natalie Dennis³, Feifei Yang⁴, Iris Lin⁴, Yiting Wang⁵, Soumya Chakravarty⁶, Claire Fischer³, May Shawi⁷, Arthur Quenéchdu³ and Joseph Merola⁸, ¹Cleveland Clinic, Cleveland, OH, ²Janssen Immunology Global Commercial Strategy Organization, Raritan, NJ, ³Amaris, Health Economics and Market Access, Paris, France, ⁴Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, ⁵Janssen R&D, LLC, Titusville, NJ, ⁶Janssen Scientific Affairs, LLC and Drexel University College of Medicine, Horsham, PA, ⁷Janssen Immunology Global Commercial Strategy Organization, Toronto, ON, Canada, ⁸Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Fatigue is a complex symptom affecting physiological, psychological, and social factors and is commonly seen in psoriatic arthritis (PsA). Fatigue has been shown to…
Abstract Number: 0240 • ACR Convergence 2021
Economic Burden of Fatigue Among Patients with Psoriatic Arthritis – a Retrospective Study Using Claims Data, 2009-2019
Joseph Merola¹, Feifei Yang², Natalie Dennis³, Steven Peterson⁴, Iris Lin², Yiting Wang⁵, Soumya Chakravarty⁶, Arthur Quenéchdu³, May Shawi⁷, Claire Fischer³ and Elaine Husni⁸, ¹Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ²Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, ³Amaris, Health Economics and Market Access, Paris, France, ⁴Janssen Immunology Global Commercial Strategy Organization, Raritan, NJ, ⁵Janssen R&D, LLC, Titusville, NJ, ⁶Janssen Scientific Affairs, LLC and Drexel University College of Medicine, Horsham, PA, ⁷Janssen Immunology Global Commercial Strategy Organization, Toronto, ON, Canada, ⁸Cleveland Clinic, Cleveland, OH
Background/Purpose: Fatigue is a complex symptom affecting physiological, psychological, and social factors and is commonly seen in psoriatic arthritis (PsA). The objectives of this study…
Abstract Number: 0304 • ACR Convergence 2021
Renal Involvement in Sjőgren’s Syndrome: Predictors and Impact on Patient Outcome
Rudrarpan Chatterjee¹, Anu Balakrishnan², Rajat Kharbanda¹, Upendra Rathore¹, Latika Gupta¹, Durga P Misra¹, Vikas Agarwal², Amita Aggarwal¹ and Able Lawrence², ¹Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India, ²Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Background/Purpose: Renal disease in primary Sjogren's syndrome (pSS) can occur in form of tubulointerstitial nephritis (TIN) or glomerulonephritis (GN). Data from India on pSS is…
Abstract Number: 0315 • ACR Convergence 2021
Sjögren’s Syndrome Symptom Diary (SSSD) and Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) as Assessments of Symptoms in Sjögren’s Syndrome: A Qualitative Exploration of Content Validity and Meaningful Change
Samantha Wratten¹, Natasha Griffiths², Carl Cooper², Jessica Flynn², Rebecca Hall³, Linda Abetz-Webb², Wolfgang Hueber⁴, Briana Ndife⁵ and Pushpendra Goswami⁴, ¹Adelphi Values, Macclesfield, United Kingdom, ²Adelphi Values, Bollington, United Kingdom, ³Adelphi Values Ltd, Bollington, United Kingdom, ⁴Novartis Pharma AG, Basel, Switzerland, ⁵Novartis, East Hanover, NJ
Background/Purpose: The aim of this study was to gain qualitative patient feedback on the appropriateness of two Patient Reported Outcome (PRO) measures as assessments of…
Abstract Number: 0462 • ACR Convergence 2021
Remotely Delivered Cognitive Behavioural and Personalised Exercise Interventions Reduce Fatigue Severity and Impact in Inflammatory Rheumatic Diseases: Results from a Multi-centre Randomised Controlled Parallel Group Trial
Eva-Maria Bachmair¹, Kathryn Martin Remmes¹, Lorna Aucott¹, Emma Dures², Richard Emsley³, Stuart Gray⁴, Elizabeth Kidd⁵, Vinod Kumar⁶, Karina Lovell⁷, Graeme MacLennan¹, Paul McNamee¹, John Norrie⁸, Lorna Paul⁹, Jon Packham¹⁰, Stuart Ralston¹¹, Stefan Siebert⁴, Alison Wearden⁷, Gary Macfarlane¹² and Neil Basu⁴, ¹University of Aberdeen, Aberdeen, United Kingdom, ²University of West of England, Bristol, United Kingdom, ³King's College London, London, United Kingdom, ⁴University of Glasgow, Glasgow, United Kingdom, ⁵Newcastle Hospitals NHS Foundation Trust, Newcastle, United Kingdom, ⁶NHS Tayside, Dundee, United Kingdom, ⁷University of Manchester, Manchester, United Kingdom, ⁸Usher Institute – University of Edinburgh, Edinburgh, United Kingdom, ⁹Glasgow Caledonian University, Glasgow, Scotland, United Kingdom, ¹⁰Midlands Partnership NHS Foundation Trust, Stoke-on-Trent, United Kingdom, ¹¹University of Edinburgh, Edinburgh, Scotland, United Kingdom, ¹²Epidemiology Group, Institute of Applied Health Sciences, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom
Background/Purpose: Inflammatory rheumatic disease (IRD) related fatigue is pervasive and disabling, even in otherwise stable disease. Although cognitive-behavioural approaches (CBAs) and personalised exercise programmes (PEP)…
Abstract Number: 0655 • ACR Convergence 2021
Depression and Fatigue: Two Forgotten Associated Comorbidities in Patients with Rheumatoid Arthritis
Rosa Morlà¹, Beatriz Frade-Sosa², Núria Sapena³, Roberto Gumucio², Raimon Sanmarti² and Jose A Gomez-Puerta², ¹Hospital Universitari Clinic de Barcelona, Barcelona, Spain, ²Hospital Clínic de Barcelona, Barcelona, Spain, ³Rheumatology Department, Hospital Clínic, Barcelona, Spain
Background/Purpose: Rheumatoid arthritis (RA) is frequently associated with different comorbidities. Depression and fatigue are common in RA patients with a prevalence of 17-39-%(1) and 40%(2)…

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