Abstracts tagged "Fatigue"

Abstract Number: 1528 • 2012 ACR/ARHP Annual Meeting
Assessing Fatigue in Systemic Vasculitis From the Patient’s Perspective
Peter C. Grayson¹, Naomi Amudala², Carol McAlear³, Renée Leduc⁴, Denise Shereff⁵, Rachel Richesson⁶, Liana Fraenkel⁷ and Peter A. Merkel⁸, ¹Section of Rheumatology & the Clinical Epidemiology Unit, Boston University School of Medicine, Vasculitis Center, Boston, MA, ²Rheumatology & Vasculitis, Boston University Medical Center, Boston, MA, ³Vasculitis Clinical Research Consortium, University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics Epidemiology Center, University of South Florida, Tampa, FL, ⁵Division of Bioinformatics and Biostatistics, University of South Florida, Tampa, FL, ⁶Epidemiology & Biostatistics, University of South Florida, Tampa, FL, ⁷Medicine, Section of Rheumatology, Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, New Haven, CT, ⁸University of Pennsylvania, Philadelphia, PA
Background/Purpose: Fatigue is considered an important disease burden by patients with vasculitis, yet mechanisms underlying fatigue are poorly understood. Physician-derived measures of vasculitis disease activity…
Abstract Number: 1394 • 2012 ACR/ARHP Annual Meeting
Health Status Burden and Impact of Fatigue On Patient Functioning in SLE Patients From a Phase 1b Study
Michelle Petri¹, Ariane K. Kawata², Ancilla W. Fernandes³, Kavita Gajria⁴, Warren Greth⁵ and Asha Hareendran⁶, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²United Biosource Corporation, Bethesda, MD, ³MedImmune, LLC, Gaithersburg, MD, ⁴MedImmune LLC, Gaithersburg, MD, ⁵Clinical Development, MedImmune, LLC, Gaithersburg, MD, ⁶United Biosource Corporation, London, MD, United Kingdom
Background/Purpose: Systemic Lupus Erythematosus (SLE) has a significant impact on patient's quality of life. Fatigue is the most common symptom of SLE and affects between…
Abstract Number: 1232 • 2012 ACR/ARHP Annual Meeting
Association of Actometer Assessed Physical Activity and Fatigue in Patients with Rheumatoid Arthritis: Patients with a Lower Daily Activity Have More Fatigue
Sanne van Dartel¹, Han Repping-Wuts¹, Dewy van Hoogmoed¹, Hans Knoop², Gijs Bleijenberg¹, Piet L.C. van Riel³ and J. Fransen³, ¹Reumatology 470, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Nijmegen Expert Centre of Chronic Fatigue, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Fatigue in rheumatoid arthritis (RA) is related to pain and disability, and several psycho-social factors such as coping strategies. In Chronic Fatigue Syndrome (CFS),…
Abstract Number: 954 • 2012 ACR/ARHP Annual Meeting
Diagnosis of Secondary Fibromyalgia in an Established Rheumatoid Arthritis Cohort
Yvonne C. Lee¹, Christine K. Iannaccone¹, Michelle A. Frits¹, M. Weinblatt² and Nancy A. Shadick³, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, ³Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: The prevalence of fibromyalgia (FM) is 7-10 times higher among rheumatoid arthritis (RA) patients than the general population. However, the diagnosis of FM in…
Abstract Number: 870 • 2012 ACR/ARHP Annual Meeting
To Love and to Hold: Men Describe Parenting in the Presence of Inflammatory Arthritis
Catherine L. Backman¹ and Alana Longson², ¹Occupational Science & Occupational Therapy, The University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Centre of Canada, Vancouver, BC, Canada
Background/Purpose: Inflammatory arthritis (IA) may limit participation in life roles such as parenting. Surprisingly little research has investigated the impact of IA on parenting tasks…
Abstract Number: 803 • 2012 ACR/ARHP Annual Meeting
Frontal Brain Connectivity to the Default Mode Network Is Associated with Subjective Fatigue Irrespective of Pain and Depression
Johnson P. Hampson¹, Daniel J. Clauw², Jieun Kim³, Vitaly Napadow⁴ and Richard E. Harris¹, ¹Anesthesiology, University of Michigan, Ann Arbor, MI, ²Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ³Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, ⁴Radiology, Martinos Center for Biomedical Imaging, Charlestown, MA
Background/Purpose: Chronic pain patients report increased levels of fatigue; however, very little is known about the underlying mechanisms of this symptom. Previous work by our…
Abstract Number: 2689 • 2012 ACR/ARHP Annual Meeting
Quality of Sleep, Physical Activity and Fatigue in Patients with Rheumatoid Arthritis. A Cross-Sectional Study
Katrine Loeppenthin¹, Bente Appel Esbensen¹, Poul Jennum², Mikkel Østergaard³, Tanja Thomsen¹ and Julie Midtgaard⁴, ¹Nursing and Health Science Research Unit, DK-2600 Glostrup, Denmark, ²Danish Centre for Sleep Medicine, Department of Clinical Neurophysiology, DK-2600 Glostrup, Denmark, ³Copenhagen University Hospital Glostrup, Copenhagen, Denmark, ⁴Health Care Research Centre, Copenhagen, Denmark
Background/Purpose: Sleep disturbances and fatigue are frequently experienced (40-70 %) in patients with rheumatoid arthritis (RA) and contribute to decreased quality of life and adverse…
Abstract Number: 557 • 2012 ACR/ARHP Annual Meeting
Effect of Certolizumab Pegol On the Multiple Facets of Psoriatic Arthritis As Reported by Patients: 24 Week Patient Reported Outcome Results of a Phase 3 Double Blind Randomized Placebo-Controlled Study
Dafna D. Gladman¹, Roy Fleischmann², Geoffroy Coteur³, Franz Woltering⁴ and Philip J. Mease⁵, ¹Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, Canada, ²University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ³UCB Pharma, Brussels, Belgium, ⁴UCB Pharma, Monheim, Germany, ⁵Seattle Rheumatology Associates, Seattle, WA
Background/Purpose: RAPID-PsA (NCT01087788) reports efficacy and safety of certolizumab pegol (CZP), a PEGylated Fc-free anti-TNF, in psoriatic arthritis (PsA).1 The effect of different imputation methodologies…
Abstract Number: 2411 • 2012 ACR/ARHP Annual Meeting
Obesity Is Associated with Higher Levels of Fatigue in RA
Patricia P. Katz¹, Vladimir Chernitskiy² and Mary Margaretten², ¹Medicine, University of California San Francisco, San Francisco, CA, ²Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Fatigue is recognized as a major problem for individuals with rheumatoid arthritis (RA), yet the causes of fatigue are not well defined. Obesity appears…
Abstract Number: 367 • 2012 ACR/ARHP Annual Meeting
Improved Fatigue-Related Quality of Life in CAPRA-2, a 12 Week Study of 5-Mg Modified (Delayed) Release Prednisone in Rheumatoid Arthritis
Rieke Alten¹, Amy Grahn², Patricia Rice³ and Frank Buttgereit⁴, ¹Department of Internal Medicine II, Schlosspark-Klinik, University Medicine, Berlin, Germany, ²Clinical Development, Horizon Pharma, Inc, Deerfield, IL, ³Statistics, CliniRx Research, Naperville, IL, ⁴Charité - Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Quality of life in rheumatoid arthritis (RA) patients can be improved by reducing the common symptom of fatigue caused by disease related factors such…
Abstract Number: 2414 • 2012 ACR/ARHP Annual Meeting
Multisite Joint Pain and Fatigue: the Role of Pain Severity and Sleep Problems in Adults with Arthritis
Mayilee Canizares¹ and E.M. Badley², ¹Arthritis Care Research and Evaluation Unit, Division of Health Care and Outcomes Research. Toronto Western Research Institute, Toronto, ON, Canada, ²Division of Health Care and Outcomes Research, Toronto Western Research Institute;Dalla Lana School of Public Health,University of Toronto, Toronto, ON, Canada
Background/Purpose: Little is known about the severity and determinants of fatigue in adults with arthritis. We hypothesize that the number of joint sites affected is…
Abstract Number: 95 • 2012 ACR/ARHP Annual Meeting
Smoking Is Associated with Worse and More Widespread Pain, Worse Disease Activity, Function, Fatigue and Health Related Quality of Life in Patients with Axial Spondyloarthritis –Results From a Population Based Cohort
Ann B. I. Bremander¹, Ingemar F. Petersson², Emma Haglund³, Stefan Bergman⁴ and Lennart TH Jacobsson⁵, ¹Department of Exercise Physiology, Biomechanics and Health, Halmstad University School of Business and Engineering, Halmstad, Sweden, ²Lund University, Lund, Sweden, ³Research and Development Centre, Spenshult Hospital for Rheumatic Diseases, Halmstad, Sweden, ⁴Spenshult Research and Development Center, Halmstad, Sweden, ⁵Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: In subjects with early axial Spondyloarthritis (SpA) smoking has recently been associated with earlier onset of disease, worse lesions of the sacroiliac joints and…
Abstract Number: 1869 • 2012 ACR/ARHP Annual Meeting
Predictors of Fatigue in Fibromyalgia
Ann Vincent¹, Mary O. Whipple², Debra L. Barton³, Daniel J. Clauw⁴, David A. Williams⁵, Terry H. Oh⁶ and Loren L. Toussaint⁷, ¹General Internal Medicine, Mayo Clinic, Rochester, MN, ²Fibromyalgia and Chronic Fatigue Clinic, Mayo Clinic, Rochester, MN, ³Oncology, Mayo Clinic, Rochester, MN, ⁴Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ⁵Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI, ⁶Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, ⁷Psychology, Luther College, Decorah, IA
Background/Purpose: Previous research suggests that fatigue in chronic diseases is multifactorial and that fatigue in fibromyalgia is worse than fatigue in rheumatoid arthritis or osteoarthritis.…

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