Abstracts tagged "Fatigue"

Abstract Number: 1548 • 2014 ACR/ARHP Annual Meeting
Treatment Effect of Ustekinumab on Fatigue in Patients with Psoriatic Arthritis: Results from a Phase 3 Clinical Trial
Christopher T. Ritchlin¹, Proton Rahman², Lluís Puig Sanz³, Alice B. Gottlieb⁴, Arthur Kavanaugh⁵, Iain B. McInnes⁶, Shu Li⁷, Yuhua Wang⁷, Rita Ganguly⁸, Alan M. Mendelsohn⁹ and Chenglong Han⁸, ¹Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ²Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ³Dermatology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁴Tufts Medical Center, Boston, MA, ⁵University of California San Diego, La Jolla, CA, ⁶Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ⁷Janssen Research & Development, LLC., Spring House, PA, ⁸Janssen Global Services, LLC., Malvern, PA, ⁹Immunology, Janssen Research & Development, LLC., Spring House, PA
Background/Purpose: To assess the treatment effect of ustekinumab on fatigue using data from PSUMMIT 2. Methods: Adult patients with active psoriatic arthritis (PsA) despite DMARD…
Abstract Number: 1382 • 2014 ACR/ARHP Annual Meeting
The Longitudinal Course of Fatigue in Rheumatoid Arthritis – Results from the Norfolk Arthritis Register
Katie L Druce¹, Gareth T Jones², Gary J. Macfarlane¹, Suzanne M. Verstappen³ and Neil Basu¹, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Musculoskeletal Research Collaboration (Epidemiology Group),, University of Aberdeen, Aberdeen, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Fatigue is common and burdensome in Rheumatoid Arthritis (RA). Though RA fatigue progression varies significantly between individuals, to date, published analyses have only considered…
Abstract Number: 1058 • 2014 ACR/ARHP Annual Meeting
Levels of Fatigue Are Dependent on Country of Residence in Rheumatoid Arthritis: An Analysis Among 3920 Patients from 17 Countries
Monika Hifinger^1,2, Polina Putrik^3,4, Sofia Ramiro^5,6, Maxime Dougados⁷, Laure Gossec⁸, Andras Keszei⁹, Ihsane Hmamouchi¹⁰ and Annelies Boonen¹¹, ¹Rheumatology, University of Maastricht, Maastricht, Netherlands, ²Rheumatology, MUMC, University Hospital Maastricht, Maastricht, Netherlands, ³Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Health Promotion, Maastricht University, Maastricht, Netherlands, ⁵Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center/University of Amsterdam, Amsterdam, Netherlands, ⁶Rheumatology, Hospital Garcia de Orta, Almada, Portugal, ⁷Cochin Hospital, Paris Descartes University, Paris, France, ⁸Rheumatology, Pierre et Marie Curie University, Paris, France, ⁹Medical Informatics, Uniklinik RWTH Aachen University, Aachen, Germany, ¹⁰Biostatistics, Epidemiology LBRCE, Mohamed V Souissi University, Rabat, Morocco, ¹¹Internal Medicine-Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: For patients with rheumatoid arthritis (RA), fatigue is an important aspect of disease which impacts quality of life. However the complex relationship between fatigue…
Abstract Number: 351 • 2014 ACR/ARHP Annual Meeting
Doctor, Will My Fatigue be Better If I’m in Remission? an Exploratory Analysis of 1284 Rheumatoid Arthritis (RA) Patients Indicates Fatigue Is the Only Aspect of Patient-Perceived Impact to Remain Significant in ACR/EULAR Boolean Remission
Laure Gossec^1,2,3, Bruno Fautrel^2,4, John Kirwan¹, Andra Balanescu¹, Maarten de Wit³, Ben A.C. Dijkmans¹, Matthias Englbrecht¹, Philippe Gaudin⁴, Feride Gogus¹, Turid Heiberg³, Tore Kristian Kvien¹, Emilio Martín-Mola⁵, Marco Matucci-Cerinic¹, Kati Otsa³, Adeline Ruyssen-Witrand⁴, Tuulikki Sokka-Isler¹, Martin Soubrier⁴ and Maxime Dougados^1,4, ¹RAID working group for EULAR, Zurich, Switzerland, ²Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France, ³PsAID taskforce, EULAR, Zurich, Switzerland, ⁴COMEDRA trial group, Paris, France, ⁵Rheumatology, Hospital Universitario La Paz, Madrid, Spain
Background/Purpose Fatigue is an important issue for patients with rheumatoid arthritis (RA). The ACR/EULAR Boolean definition of remission comprises values 1/10) is a status which…
Abstract Number: 126 • 2013 ACR/ARHP Annual Meeting
Subgrouping Of Rheumatoid Arthritis Patients Based On Pain, Fatigue, Inflammation and Psychosocial Factors
Yvonne C. Lee¹, Michelle A. Frits¹, Christine K. Iannaccone¹, Michael E. Weinblatt¹, Nancy A. Shadick², David A. Williams³ and Jing Cui¹, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA, ³Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI
Background/Purpose: Among rheumatoid arthritis (RA) patients, pain may be due to peripheral inflammation or other causes, such as central pain mechanisms. The objective was to…
Abstract Number: 135 • 2013 ACR/ARHP Annual Meeting
Evaluation Of The Quality Of Life and Sleep In Patients With Benign Joint Hypermobility Syndrome
Ilknur Albayrak¹, Halim Yilmaz¹, Ekrem Akkurt², Ali Salli³ and Gulten Karaca⁴, ¹The Department of Physical Medicine and Rehabilitation, Konya Education and Research Hospital, MD, Konya, Turkey, ²The Department of Physical Medicine and Rehabilitation, Konya Education and Research Hospital, Konya, Turkey, MD, Konya, Turkey, ³The Department of Physical Medicine and Rehabilitation, Necmettin Erbakan University, Meram Faculty of Medicine, MD, KONYA, Turkey, ⁴1The Department of Physical Medicine and Rehabilitation, Konya Education and Research Hospital, Konya, Turkey, MD, Konya, Turkey
Background/Purpose: Traction injuries at tendon or ligament attachment sites, joint instability, low back, back and neck pain can be seen in patients with benign joint…
Abstract Number: 2273 • 2013 ACR/ARHP Annual Meeting
Patient Survey Challenges Conventional Notions Regarding Symptoms and Experiences Of People Living With Rheumatoid Arthritis
Kelly O'Neill Young¹, Cynthia S. Crowson² and Dana M. Symons¹, ¹Rheumatoid Patient Foundation, Cocoa, FL, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: While rheumatoid arthritis (RA) has been studied for decades, many aspects of the disease are not well understood. Like systemic lupus erythematosus, RA manifests…
Abstract Number: 2243 • 2013 ACR/ARHP Annual Meeting
How Well Do The Three Generic Patient Reported Outcomes Measurement Information System Fatigue Instruments Perform In Rheumatoid Arthritis?
Susan J. Bartlett^1,2, Ana-Maria Orbai³, Trisha Duncan³ and Clifton O. Bingham III³, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD
Background/Purpose: NIH Patient-Reported Outcomes Measurement Information System (PROMIS) has created highly precise and efficient instruments to measure patient-reported outcomes across health domains relevant to chronic…
Abstract Number: 751 • 2013 ACR/ARHP Annual Meeting
Fatigue, Pain, and Functional Disability Among Patients With Vasculitis
Antoine G. Sreih^1,2, Narender Annapureddy³ and Osama Elsallabi⁴, ¹Medicine/Division of Rheumatology, The University of Pennsylvania, Philadelphia, PA, ²Medicine/Rheumatology, Rush University Medical Center, Chicago, IL, ³Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Medicine, Creighton University, Omaha, NE
Background/Purpose: Vasculitis is a heterogeneous group of diseases often resulting in severe morbidity affecting patients’ quality of life. These morbidities are generally attributed to disease…
Abstract Number: 2689 • 2012 ACR/ARHP Annual Meeting
Quality of Sleep, Physical Activity and Fatigue in Patients with Rheumatoid Arthritis. A Cross-Sectional Study
Katrine Loeppenthin¹, Bente Appel Esbensen¹, Poul Jennum², Mikkel Østergaard³, Tanja Thomsen¹ and Julie Midtgaard⁴, ¹Nursing and Health Science Research Unit, DK-2600 Glostrup, Denmark, ²Danish Centre for Sleep Medicine, Department of Clinical Neurophysiology, DK-2600 Glostrup, Denmark, ³Copenhagen University Hospital Glostrup, Copenhagen, Denmark, ⁴Health Care Research Centre, Copenhagen, Denmark
Background/Purpose: Sleep disturbances and fatigue are frequently experienced (40-70 %) in patients with rheumatoid arthritis (RA) and contribute to decreased quality of life and adverse…
Abstract Number: 557 • 2012 ACR/ARHP Annual Meeting
Effect of Certolizumab Pegol On the Multiple Facets of Psoriatic Arthritis As Reported by Patients: 24 Week Patient Reported Outcome Results of a Phase 3 Double Blind Randomized Placebo-Controlled Study
Dafna D. Gladman¹, Roy Fleischmann², Geoffroy Coteur³, Franz Woltering⁴ and Philip J. Mease⁵, ¹Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, Canada, ²University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ³UCB Pharma, Brussels, Belgium, ⁴UCB Pharma, Monheim, Germany, ⁵Seattle Rheumatology Associates, Seattle, WA
Background/Purpose: RAPID-PsA (NCT01087788) reports efficacy and safety of certolizumab pegol (CZP), a PEGylated Fc-free anti-TNF, in psoriatic arthritis (PsA).1 The effect of different imputation methodologies…
Abstract Number: 2411 • 2012 ACR/ARHP Annual Meeting
Obesity Is Associated with Higher Levels of Fatigue in RA
Patricia P. Katz¹, Vladimir Chernitskiy² and Mary Margaretten², ¹Medicine, University of California San Francisco, San Francisco, CA, ²Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Fatigue is recognized as a major problem for individuals with rheumatoid arthritis (RA), yet the causes of fatigue are not well defined. Obesity appears…
Abstract Number: 367 • 2012 ACR/ARHP Annual Meeting
Improved Fatigue-Related Quality of Life in CAPRA-2, a 12 Week Study of 5-Mg Modified (Delayed) Release Prednisone in Rheumatoid Arthritis
Rieke Alten¹, Amy Grahn², Patricia Rice³ and Frank Buttgereit⁴, ¹Department of Internal Medicine II, Schlosspark-Klinik, University Medicine, Berlin, Germany, ²Clinical Development, Horizon Pharma, Inc, Deerfield, IL, ³Statistics, CliniRx Research, Naperville, IL, ⁴Charité - Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Quality of life in rheumatoid arthritis (RA) patients can be improved by reducing the common symptom of fatigue caused by disease related factors such…
Abstract Number: 2414 • 2012 ACR/ARHP Annual Meeting
Multisite Joint Pain and Fatigue: the Role of Pain Severity and Sleep Problems in Adults with Arthritis
Mayilee Canizares¹ and E.M. Badley², ¹Arthritis Care Research and Evaluation Unit, Division of Health Care and Outcomes Research. Toronto Western Research Institute, Toronto, ON, Canada, ²Division of Health Care and Outcomes Research, Toronto Western Research Institute;Dalla Lana School of Public Health,University of Toronto, Toronto, ON, Canada
Background/Purpose: Little is known about the severity and determinants of fatigue in adults with arthritis. We hypothesize that the number of joint sites affected is…
Abstract Number: 95 • 2012 ACR/ARHP Annual Meeting
Smoking Is Associated with Worse and More Widespread Pain, Worse Disease Activity, Function, Fatigue and Health Related Quality of Life in Patients with Axial Spondyloarthritis –Results From a Population Based Cohort
Ann B. I. Bremander¹, Ingemar F. Petersson², Emma Haglund³, Stefan Bergman⁴ and Lennart TH Jacobsson⁵, ¹Department of Exercise Physiology, Biomechanics and Health, Halmstad University School of Business and Engineering, Halmstad, Sweden, ²Lund University, Lund, Sweden, ³Research and Development Centre, Spenshult Hospital for Rheumatic Diseases, Halmstad, Sweden, ⁴Spenshult Research and Development Center, Halmstad, Sweden, ⁵Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden
Background/Purpose: In subjects with early axial Spondyloarthritis (SpA) smoking has recently been associated with earlier onset of disease, worse lesions of the sacroiliac joints and…

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