Abstracts tagged "Fatigue"

Abstract Number: 2335 • 2015 ACR/ARHP Annual Meeting
How Much Does Fatigue Contribute to the Physician and Patient Global Estimates in Different Rheumatic Diseases? Analysis from Routine Care on a Multidimensional Health Assessment Questionnaire (MDHAQ)
Isabel Castrejón¹, Elena Nikiphorou², Ruchi Jain¹, Annie Huang¹, Joel A. Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, Addenbrooke's Hospital, Cambridge, United Kingdom, ³Rush University Medical Center, Chicago, IL
Background/Purpose: Fatigue is an important problem for many patients with rheumatic diseases. Fatigue is associated with disease severity, psychological distress, and a poorer quality of…
Abstract Number: 2337 • 2015 ACR/ARHP Annual Meeting
Depression, Bad Sleep Quality, and Functional Deficit Are Independently Associated with Persistent Fatigue in Arthritic Patients with Low Disease Activity Under Biological Dmards
Vitalie Nizeica¹, Myriam Normand², Delphine Denarie¹, Béatrice Pallot Prades¹, Philippe Collet¹, Adamah Amouzougan¹, Hervé Locrelle^1,2, Thierry Thomas^1,2 and Hubert Marotte^1,2, ¹Rheumatology Department, University Hospital of Saint-Etienne, Saint-Etienne, France, ²INSERM U1059/LBTO, Université de Lyon - Université Jean Monnet, Saint-Etienne, France
Background/Purpose: In rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA) patients, fatigue has been mainly related to disease activity. Current management of rheumatic inflammatory diseases aims…
Abstract Number: 2637 • 2015 ACR/ARHP Annual Meeting
Prevalence of Unacceptable Pain and the Risk of Fatigue and Sleeping Problems in Early Rheumatoid Arthritis Patients
Joakim Lindqvist¹, Maria Sandberg^2,3, Saedis Saevarsdottir⁴, Reem Altawil⁴, Lars Klareskog⁵, Lars Alfredsson⁶ and Jon Lampa⁷, ¹Rheumatology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden, ²Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, ³The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁵Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁶Unit of Cardiovascular Epidemiology, Institute of Enviornmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, ⁷Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Pain is a commonly reported cause of affliction in RA-patients, also after adequate anti-rheumatic treatment. The objective of this study was to investigate the…
Abstract Number: 2638 • 2015 ACR/ARHP Annual Meeting
Multiple Psychosocial Factors Influence Subjective Assessments of Disease Activity in Rheumatoid Arthritis
Ying L. Liu¹, Joan M. Bathon^2,3 and Jon T. Giles⁴, ¹Internal Medicine, Columbia University Medical Center, New York, NY, ²Medicine, Columbia University, College, New York, NY, ³Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁴Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Measuring disease activity in rheumatoid arthritis (RA) is important in evaluating efficacy of treatments, but many tests are subjective and lead to discordance in…
Abstract Number: 2681 • 2015 ACR/ARHP Annual Meeting
Physical Function, Sleep, Depression but Not CRP Level Is Associated with Fatigue in Patients with Established Rheumatoid Arthritis
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio³ and Larry W. Moreland⁴, ¹Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ³Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ⁴Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Rheumatoid arthritis (RA) is characterized by inflammation of the joints and fatigue. Although many studies have identified risk factors for RA-associated fatigue, few studies…
Abstract Number: 2883 • 2015 ACR/ARHP Annual Meeting
Relationship Between Improvements in Fatigue and Signs & Symptoms of Active Psoriatic: Arthritis a Sub-Analysis of a Phase 3 Study with Secukinumab
Laure Gossec¹, Tore K. Kvien², Philip G. Conaghan³, Mikkel Østergaard⁴, Juan D. Cañete⁵, C. Gaillez⁶, Shephard Mpofu⁶, Bintu Sherif⁷ and Steffen Jugl⁸, ¹Rheumatology Department, Paris 06 University,Hôpital Pitié Salpêtrière, Paris, France, ²Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ⁴Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ⁵Rheumatology, Hospital Clinic and IDIBAPS, Barcelona, Spain, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷RTI Health Solutions, Durham, NC, ⁸BF I&D GPA, Health Economics and Outcomes Research, Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Fatigue is highly important to patients (pts) with psoriatic arthritis (PsA). Secukinumab, an anti-interleukin-17A monoclonal antibody, significantly improved the signs and symptoms of active…
Abstract Number: 3243 • 2015 ACR/ARHP Annual Meeting
A Randomized Controlled Trial for a Physical Activity Intervention for RA Fatigue
Patricia P. Katz¹, Mary Margaretten², Steven Gregorich¹, Sandi Kaplan³, Stephanie Rush⁴ and Laura Trupin¹, ¹Medicine, University of California San Francisco, San Francisco, CA, ²Medicine, University of California, San Francisco, San Francisco, CA, ³Arthritis Research Group, University of California, San Francisco, CA, ⁴University of California, San Francisco, San Francisco, CA
Background/Purpose: Fatigue is a major problem for people with RA. Physical inactivity is an indirect risk factor for fatigue1. We tested the effect of a…
Abstract Number: 388 • 2015 ACR/ARHP Annual Meeting
Pain, Fatigue and the Psychological Impact on Health-Related Quality of Life in Childhood-Onset Lupus
Jordan T. Jones¹, Natoshia Cunningham², Catherine Donnelly³, Susmita Kashikar-Zuck⁴ and Hermine I. Brunner⁵, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Internal Medicine, University of Cincinnati, Cincinnati, OH, ⁴Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Childhood-onset lupus (cSLE) is a chronic autoimmune disease that has negative impact on health-related quality of life (HRQoL), especially when increased disease activity and…
Abstract Number: 741 • 2015 ACR/ARHP Annual Meeting
Satisfaction and Impact Associated with the Addition of Belimumab to Systemic Lupus Erythematosus (SLE) Treatment: A Cross-Sectional Survey of US Rheumatologists and Their Patients
Katie Pascoe¹, Steve Lobosco², David Bell³, Ben Hoskin³, Sulabha Ramachandran⁴, Bonnie Pobiner⁵ and David Chang⁶, ¹Value Evidence and Outcomes, GlaxoSmithKline, Uxbridge, United Kingdom, ²Adelphi Real World Ltd., Macclesfield, United Kingdom, ³Autoimmune, Adelphi Real World Ltd., Manchester, United Kingdom, ⁴Value Evidence and Outcomes, GlaxoSmithKline, Renaissance Centre, PA, ⁵Immuno-Inflammation Therapy Area, GlaxoSmithKline, Triangle Park, NC, ⁶US Medical Affairs, GlaxoSmithKline, Philadelphia, PA
Background/Purpose: Patient and physician treatment satisfaction influences long-term adherence with a treatment regimen. The primary objective was to identify factors linked to satisfaction with the…
Abstract Number: 1192 • 2015 ACR/ARHP Annual Meeting
The F-Word: Why Is Talking about Fatigue so Hard?
Ruth Hart¹, Katie Hackett², Julia Newton³, Wan-Fai Ng^3,4 and Ben Thompson^4,5, ¹Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom, ²Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ³Newcastle University, Newcastle upon Tyne, United Kingdom, ⁴Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom, ⁵Newcastle University, Newcastle-upon-Tyne, United Kingdom
Background/Purpose: Fatigue is a common symptom for people with inflammatory arthritis and associated auto-immune conditions. Its impact is wide-ranging and significantly reduces health-related quality of…
Abstract Number: 2397 • 2014 ACR/ARHP Annual Meeting
Improvement of Fatigue in Patients with Rheumatoid Arthritis Treated with Biologics: Relationship with Sleep Disorders, Depression and Clinical Efficacy. a Prospective, Multicenter Study
Marlène Genty¹, Marie Kostine², Elodie Ardouin³, Bernard Combe⁴ and Cédric Lukas⁵, ¹RHEUMATOLOGY, CHU LAPEYRONIE, MONTPELLIER, France, ²Rheumatology, CHU Pellegrin, Bordeaux, France, ³Rheumatology, Limoges University Hospital, Limoges, France, ⁴Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, ⁵Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France
Background/Purpose The functional burden of disease in Rheumatoid arthritis (RA) patients, mainly caused by inflamed joints, is often worsened by extra-articular manifestations, among which asthenia remains…
Abstract Number: 2330 • 2014 ACR/ARHP Annual Meeting
Construct Validity of the Adult Myopathy Assessment Tool in Individuals with Inclusion Body Myositis
Michael Harris-Love¹, Galen Joe², Todd Davenport³, Joseph Shrader², Beverly McElroy⁴, Goran Rakocevic⁵, Olavo Vasconcelos⁶ and Marinos Dalakas⁵, ¹Geriatrics Service, VA Medical Ctr, Washington, DC, ²Rehabilitation Medicine Department, National Institutes of Health, Bethesda, MD, ³Department of Physical Therapy, University of the Pacific, Stockton, CA, ⁴National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, ⁵Department of Neurology, Thomas Jefferson University, Philadelphia, PA, ⁶Department of Neurology, Richmond Veterans Affairs Medical Center, Richmond, VA
Background/Purpose The Adult Myopathy Assessment Tool (AMAT) is a 13-item performance-based battery developed to assess function and anaerobic endurance in adults with muscle disease. The…
Abstract Number: 2227 • 2014 ACR/ARHP Annual Meeting
Physical Impairment in Patients with Idiopathic Inflammatory Myopathies Is Predicted By the American College of Rheumatology Functional Status Measure
Laura Cleary¹, Leslie J. Crofford², Archana Srinivas¹, Heather Bush¹, Catherine Starnes¹, Qian Fan¹, Jidan Duan¹, Kirk Jenkins¹, Natasha Fraser¹, Matthew Rutledge¹ and Beatriz Hanaoka³, ¹University of Kentucky, Lexington, KY, ²Div of Rheumatology & Immunology, Vanderbilt University, Nashville, TN, ³Rheumatology, University of Kentucky, Lexington, KY
Background/Purpose The American College of Rheumatology classification criteria of functional status (ACR-FS) in Rheumatoid Arthritis is used as a measure of the consequences of impairment…
Abstract Number: 2081 • 2014 ACR/ARHP Annual Meeting
Ehlers-Danlos Hypermobile (EDS-HT) Patients and Postural Instability : Another Clue to Explain Pain and Fatigue ?
Roland Jaussaud¹, Elodie Vlamynck², Rami Haidar³, Dorothée Lambert⁴, Violaine Laurant-Noel⁵ and Amélie Servettaz⁵, ¹Médecine interne, maladies infectieuses, immunologie clinique, CHU de Reims, REIMS, France, ²Cabinet d'Orthopédie, Versailles, France, ³Cabinet d'Orthopédie, Lille, France, ⁴Médecine interne, maladies infectieuses, Immunologie clinique, CHU Reims, Reims, France, ⁵Médecine interne, maladies infectieuses, immunologie clinique, Hôpital Robert Debré. CHU de Reims, Reims, France
Background/Purpose Postural instability was found in several functional disorders including dyslexia, chronic pain and fibromyalgia. Furthermore, the link between vertical heterophoria (VH) and postural control…
Abstract Number: 1548 • 2014 ACR/ARHP Annual Meeting
Treatment Effect of Ustekinumab on Fatigue in Patients with Psoriatic Arthritis: Results from a Phase 3 Clinical Trial
Christopher T. Ritchlin¹, Proton Rahman², Lluís Puig Sanz³, Alice B. Gottlieb⁴, Arthur Kavanaugh⁵, Iain B. McInnes⁶, Shu Li⁷, Yuhua Wang⁷, Rita Ganguly⁸, Alan M. Mendelsohn⁹ and Chenglong Han⁸, ¹Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ²Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ³Dermatology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁴Tufts Medical Center, Boston, MA, ⁵University of California San Diego, La Jolla, CA, ⁶Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ⁷Janssen Research & Development, LLC., Spring House, PA, ⁸Janssen Global Services, LLC., Malvern, PA, ⁹Immunology, Janssen Research & Development, LLC., Spring House, PA
Background/Purpose: To assess the treatment effect of ustekinumab on fatigue using data from PSUMMIT 2. Methods: Adult patients with active psoriatic arthritis (PsA) despite DMARD…

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