Abstracts tagged "Fatigue"

Abstract Number: 2557 • ACR Convergence 2025
Relationship Between Sleep Quality and Psychiatric Symptoms in Autoimmune Rheumatic Diseases
Karen Yaresi Ramos-Reza¹, Maria Eugenia Corral-Trujillo², Eva Abigaid Galindo-Calvillo¹, Joselyn Aracely Alvarez Meza¹, Fatima Adriana Marin.Muñoz¹, Santiago S. Heredia-Gonzalez¹, Laura Patricia Gallegos-Gloria¹, Norberto Luna-Mireles¹, Estefania Escamilla-Barrientos¹, Alicia Abigail Treviño-Arreola¹, Fatima Humphrey-Escamilla¹, Jesus Alberto Cardenas-de la Garza³, Miguel Villarreal-Alarcón⁴, Ivan de Jesús Hernandez-Galarza¹ and Dionicio A. Galarza-Delgado⁵, ¹Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Nuevo Leon, Mexico, ²Universidad Autónoma de Nuevo León, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, México., Monterrey, Nuevo Leon, Mexico, ³Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, ⁴Hospital Universitario UANL, Monterrey, Nuevo León, Mexico, ⁵Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico
Background/Purpose: Autoimmune Rheumatic Diseases (ARDs) commonly present with psychiatric symptoms such as chronic fatigue, depression, and anxiety, and often linked to poor sleep quality. Prolonged…
Abstract Number: 0644 • ACR Convergence 2025
Improvement of Fatigue, Musculoskeletal Pain, and Morning Stiffness in Patients with Systemic Lupus Erythematosus Treated with Dapirolizumab Pegol: 48-Week Results from a Phase 3 Trial
Ioannis Parodis¹, Caroline Gordon², Joan Merrill³, Matthias Schneider⁴, Zahi Touma⁵, Teri Jimenez⁶, Thomas Morel⁷, Mina Nejati⁸, Christian Stach⁹, Christine de La Loge¹⁰ and Laurent arnaud¹¹, ¹Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology, Stockholm, Sweden, ²Department of Inflammation and Ageing, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom, ³Oklahoma Medical Research Foundation, Oklahoma City ⁷³¹⁰⁴, OK, ⁴Clinic of Rheumatology and Hiller Research Unit, Heinrich-Heine-University, Düsseldorf, Germany, ⁵University of Toronto, Toronto, ON, Canada, ⁶UCB, Raleigh, NC, ⁷UCB, Basel, Switzerland, ⁸Biogen, Cambridge, MA, ⁹UCB, Monheim am Rhein, Germany, ¹⁰UCB, Brussels, Belgium, ¹¹Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, INSERM UMR-S ¹¹⁰⁹, Strasbourg, France, Strasbourg, France
Background/Purpose: Fatigue, musculoskeletal pain, and joint stiffness are common manifestations of SLE, presenting considerable treatment challenges, particularly in addressing chronic fatigue. Dapirolizumab pegol (DZP) is…
Abstract Number: 2536 • ACR Convergence 2025
High Levels of Fatigue and Poor Sleep Quality in Behçet’s Disease: a Cross-sectional Study from a Non-endemic Area
Mateus Augusto Rangel Nunes, Carlos Teixeira, Laurie Kumano, Gabriela Gutierrez, Vitor Grotti, Ana Paula Toledo Del Rio, Ibsen Coimbra, Alisson Pugliesi and Zoraida Sachetto, UNICAMP, Campinas, Brazil
Background/Purpose: Behçet's disease (BD) is a chronic systemic inflammatory disease classified as a variable vessel vasculitis of unknown etiology. It is marked by recurrent oral…
Abstract Number: 0517 • ACR Convergence 2025
Gut Microbiota Dysbiosis and Clinical Predictors of Fatigue in Primary Sjögren’s Syndrome: A Multi-Omics Study
Qiguo Cui¹, Pan Wang², Bin Zhou¹ and QIn Huang³, ¹Southern Medical Univercity Nanfang Hospital, guang zhou, China (People's Republic), ²southern medical university Nanfang Hospital, Guangzhou, China (People's Republic), ³Nanfang Hospital, Guangzhou, China (People's Republic)
Background/Purpose: Fatigue affects 70% of primary Sjögren's syndrome (pSS) patients, but its mechanisms remain unclear. We investigated clinical predictors and gut microbiota associations in pSS-related…
Abstract Number: 2437 • ACR Convergence 2025
Bupropion for Lupus-Induced Fatigue Treatment (B-LIFT): A Retrospective Analysis
Aaron Smith¹, Thuyvan Phan², Leah Luizza³, Anthony Trujillo³, Becki Cleveland¹, Shruti Saxena Beem⁴, Tessa Englund⁵, Claire Timon⁴ and Saira Sheikh⁵, ¹University of North Carolina, Chapel Hill, NC, ²UNC Health, Chapel Hill, NC, ³University of North Carolina, Chapel Hill, ⁴University of North Carolina at Chapel Hill, Chapel Hill, ⁵University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, multi-system autoimmune disease with heterogenous presentation. Most patients with SLE report fatigue or brain fog, which often…
Abstract Number: 0380 • ACR Convergence 2025
Multidimensional Health Assessment Questionnaire (MDHAQ)/RAPID3, is an Useful Tool to Assess Comorbid and Residual Fatigue in Rheumatoid Arthritis Patients
Rosa Maria Morlà Novell¹, Beatriz Frade Sosa², Maria López-Lasanta³, Meritxell Sallés Lizarzáburu⁴, Noemí Busquets Pérez⁵, Georgina Salvador Alarcón⁶, Marta Valls Roc⁷, Virginia Ruiz-Esquide⁸, Lola Tobalina Mastre⁹, Raimon Sanmartí⁸ and José Gomez-Puerta¹⁰, ¹Hospital Clínic de Barcelona, Barcelona, Spain, ²Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ³Hospital Universitari Vall d´Hebron, Barcelona, Spain, ⁴Xarxa Sanitària Althaia Manresa, Manresa, Spain, ⁵Hospital de Granollers, Granollers, Spain, ⁶Hospital Universitari Mùtua Terrassa, Terrassa, Spain, ⁷Hospital Universitari Dr Trueta, Girona, Sudan, ⁸Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, ⁹IDIBAPS. Hospital Clinic de Barcelona, Barcelona, ¹⁰Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain
Background/Purpose: Fatigue is a highly prevalent (40%-70%)1 comorbidity in rheumatoid arthritis (RA) patients, and residual fatigue has been described in a significant proportion of patients…
Abstract Number: 2429 • ACR Convergence 2025
mHealth-enabled Peer Coaching for Fatigue in Systemic Lupus Erythematosus (SLE): Preliminary Results from the Restore Energy, Activity Can Help (REACH) Pilot Randomized Controlled Trial
Shanthini Kasturi¹, Erin Morrissey¹, Anna Deck², Nina Gulati², Zoe Gilbard², Kiran Singh¹, Monique Gore-Massy³, Faye Chiu⁴, Priscilla Calvache⁵, Jillian Rose-Smith⁵, Andre Ogura⁶, Lucas Ogura Dantas⁶, Wambui Machua⁷, Julia Nguyen⁸, Lisa Mandl⁵, Hocine Tighiouart¹, Ludovic Trinquart², Iris Navarro-Millan⁹ and Sara Folta¹⁰, ¹Tufts Medical Center, Boston, MA, ²Tufts University School of Medicine, Boston, MA, ³N/A, West Orange, NJ, ⁴N/A, New York, NY, ⁵Hospital for Special Surgery, New York, NY, ⁶Ambulomics, Arlington, MA, ⁷Piedmont Healthcare, Atlanta, GA, ⁸Hospital for Special Surgery, New York, ⁹Weill Cornell Medicine, Hospital for Special Surgery, Poughkeepsie, NY, ¹⁰Tufts Friedman School of Nutrition, Boston, MA
Background/Purpose: Fatigue is a highly prevalent and debilitating symptom affecting up to 90% of individuals living with systemic lupus erythematosus (SLE). Despite its significant impact,…
Abstract Number: 0379 • ACR Convergence 2025
Do Rheumatoid Arthritis Patients have Residual Fatigue Without Swollen Joints and Laboratory Inflammation? A Multicenter Study
Rosa Maria Morlà Novell¹, Enrique González-Dávila², Beatriz Frade Sosa³, Maria López-Lasanta⁴, Noemí Busquets Pérez⁵, Marta Valls Roc⁶, Meritxell Sallés Lizarzáburu⁷, Georgina Salvador Alarcón⁸, Virginia Ruiz-Esquide⁹, Lola Tobalina Mastre¹⁰, José Gomez-Puerta¹¹ and Raimon Sanmartí⁹, ¹Hospital Clínic de Barcelona, Barcelona, Spain, ²Departamento de Matemáticas. Universidad de La Laguna, Tenerife, Spain, ³Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ⁴Hospital Universitari Vall d´Hebron, Barcelona, Spain, ⁵Hospital de Granollers, Granollers, Spain, ⁶Hospital Universitari Dr Trueta, Girona, Sudan, ⁷Xarxa Sanitària Althaia Manresa, Manresa, Spain, ⁸Hospital Universitari Mùtua Terrassa, Terrassa, Spain, ⁹Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, ¹⁰IDIBAPS. Hospital Clinic de Barcelona, Barcelona, ¹¹Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain
Background/Purpose: Residual fatigue highlights an unmet prevalent1 need in rheumatoid arthritis (RA) patients despite achieving remission of disease activity according to activity indices (DAS28).We examine…
Abstract Number: 2378 • ACR Convergence 2025
Factors Associated With Fatigue In Systemic Lupus Erythematosus: Data From The Almenara Lupus Cohort
Alvaro Oyarce-Calderón¹, Rocío Gamboa-Cárdenas², Victor Pimentel-Quiroz³, Samira Garcia-Hirsh⁴, Zoila Rodríguez-Bellido⁵, Cesar Pastor-Asurza⁶, Risto Perich-Campos⁷, Graciela Alarcón⁸ and Manuel Ugarte-Gil⁹, ¹Hospital Nacional Guillermo Almenara Irigoyen, San Miguel, Lima, Peru, ²Universidad Científica del Sur, Lima, Peru, ³Universidad Científica del Sur, San Isidro, Peru, ⁴Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru, ⁵Hospital Nacional Guillermo Almenara Irigoyen; Universidad Nacional Mayor de San Marcos, Lima, Peru, ⁶Hospital Nacional Guillermo Almenara Irigoyen, Lima, Pakistan, ⁷Hospital Nacional Guillermo Almenara Irigoyen; Universidad Nacional Mayor de San Marcos, La Molina, Peru, ⁸The University of Alabama at Birmingham, Oakland, CA, ⁹Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Científica del Sur, Lima, Peru; Hospital Guillermo Almenara Irigoyen, EsSalud, Lima, Peru, Lima, Peru
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a wide spectrum of clinical manifestations, fatigue being one of them; it is…
Abstract Number: 0295 • ACR Convergence 2025
Multidimensional Analysis of Fatigue in Idiopathic Inflammatory Myopathies: Clinical, Psychological, and Sociodemographic Determinants
Manali Sarkar¹, Meera Shah², Vincenzo Venerito³, Vikas Agarwal⁴ and Latika Gupta⁵, ¹Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, ²Indraprastha Apollo Hospital, New Delhi, Mumbai, Maharashtra, India, ³Univeristy of Bari "Aldo Moro", Italy, Bari, Bari, Italy, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, ⁵School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom
Background/Purpose: Fatigue significantly impacts quality of life in idiopathic inflammatory myopathies (IIM) but remains poorly understood. This study aimed to identify the key determinants of…
Abstract Number: 2254 • ACR Convergence 2025
Association of disease activity with insomnia, depression, and fatigue in patients with rheumatoid arthritis: a multicenter prospective observational study
Misako Higashida-Konishi¹, Keisuke Izumi², Shuntaro Saito Saito³, Hiroki Tabata⁴, Satoshi Hama⁴, Tatsuhiro Oshige⁴, Yutaka Okano⁴, Hisaji Oshima⁴, Katsuya Suzuki⁴, Jiro Sakamoto⁵, Toshikazu Fukami⁵, Kazumichi Minato⁵, Nobuhiko Kajio⁶, Yasushi Kondo³, Hiroaki Taguchi⁶ and Yuko Kaneko³, ¹NHO Tokyo Medical Center, Tokyo Meguroku, Japan, ²Division of Rheumatology, Department of Medicine, NHO Tokyo Medical Center/Keio University School of Medicine/TechDoctor, Inc., Tokyo, Japan, ³Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ⁴Division of Rheumatology, Department of Medicine, NHO Tokyo Medical Center, Tokyo, Japan, ⁵TechDoctor, Inc., Tokyo, Japan, ⁶Department of Rheumatology, Kawasaki Municipal Hospital, Kanagawa, Japan
Background/Purpose: Patients with rheumatoid arthritis (RA) often experience not only joint-related symptoms but also systemic issues such as insomnia, depression, and fatigue [1–3]. These symptoms…
Abstract Number: 0207 • ACR Convergence 2025
The Feasibility and Clinical Effects of Anti-Inflammatory Diet Intervention In Patients Diagnosed With Long COVID (Post-Acute Sequelae of SARS CoV-2, PASC)
Suzi Hong¹, Marcos Monteon², Kathleen Bundy³, Chloe Delgado Ramirez³, Phoebe Senowitz³, Monica Guma⁴, Nina Acebo⁵, Chris Pruitt⁶, Tanya Shekhtman³, Shahrokh Golshan⁷ and Susan Lee⁸, ¹Herbert Wertheim School of Public Health and Human Longevity Science UCSD; Department of Psychiatry UCSD, San Diego, ²University of California, San Diego, San Diego, ³Department of Family Medicine, Center for Integrative Health, Krupp Endowment Fund, UCSD, La Jolla, ⁴University of California San Diego, San Diego, CA, ⁵University of California, San Diego, La Jolla, ⁶Herbert Wertheim School of Public Health and Human Longevity Science, UCSD, La Jolla, ⁷Department of Pyschiatry, UCSD, La Jolla, ⁸Department of Medicine, University of California, San Diego, La Jolla, CA
Background/Purpose: There have been over 777 million cases of acute COVID-19 infections worldwide as of April 2025. Although many patients recover, an estimated 10-30% of…
Abstract Number: 1854 • ACR Convergence 2025
Resting-State Functional Magnetic Resonance Imaging Analysis Revealed Altered Functional Connectivity Associated with Fatigue in Systemic Lupus Erythematosus
Yujie Song¹, Nobuya Abe¹, Yuichiro Fujieda², Kodai Sakiyama¹, Yuta Inoue¹, Kenichi Miyamoto¹, Kazuro Kamada¹, Yotaro Oki¹, Maria Tada¹, Shuhei Takeyama¹, Ryo Hisada², Michihito Kono² and Tatsuya Atsumi², ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
Background/Purpose: Fatigue is one of the most frequent constitutional symptoms in systemic lupus erythematosus (SLE), usually accompanied with impaired quality of life. Resting-state functional magnetic…
Abstract Number: 1711 • ACR Convergence 2025
Dysfunctional Neurobiology Of The Insula Characterizes Fatigue In Psoriatic Arthritis
Andrew McGucken¹, Flavia Sunzini², Kristian Stefanov¹, Joel Parkinson¹, Salim Al-Wasity¹, John McLean¹, Gordon Waiter³, Stefan Siebert¹ and Neil Basu⁴, ¹University of Glasgow, Glasgow, United Kingdom, ²Glasgow University, Glasgow, United Kingdom, ³University of Aberdeen, Aberdeen, United Kingdom, ⁴Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Fatigue is a pervasive and burdensome symptom for people with psoriatic arthritis (PsA). The mechanisms underlying PsA related fatigue are unknown. In other clinical…
Abstract Number: 1551 • ACR Convergence 2025
Disease Burden and Treatment Preferences for Systemic Lupus Erythematosus: Results from a Global Real-World Survey
Zahi Touma¹, Christopher Saffore², Karim Masri³, Jerry Clewell³, Emily Goddard⁴, Grace O'Neill⁴, Madelane Foxall⁴ and Karen H. Costenbader⁵, ¹University of Toronto, Toronto, ON, Canada, ²AbbVie Inc., waukegan, IL, ³AbbVie Inc., North Chicago, IL, ⁴Adelphi Real World, Bollington, United Kingdom, ⁵Harvard Medical School and Brigham and Women's Hospital, Boston, MA
Background/Purpose: As new treatment options for systemic lupus erythematosus (SLE) become available, understanding patient burden and preferences is key to optimizing shared decision-making. This study…

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