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Abstracts tagged "extraarticular manifestations"

  • Abstract Number: 645 • 2018 ACR/ARHP Annual Meeting

    Real World Secukinumab Study in Ankylosing Spondylitis and Psoriatic Arthritis – Comorbidities and Extraarticular Manifestations: Incidence and Status throughout a Non-Interventional Study in Germany

    Uta Kiltz1, Peter Kaestner2, Holger Krauel2, Ilka Schwarze3, Jan Brandt-Juergens4, Monika Maier-Peuschel5, Carolin Legeler5, Justyna Veit5 and Hans-Peter Tony6, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumatology, Ambulantes Rheumazentrum, Erfurt, Germany, 3Praxis internistische Rheumatologie, Leipzig, Germany, 4Rheumatology, Rheumatologische Schwerpunktpraxis, Berlin, Germany, 5Novartis Pharma GmbH, Nürnberg, Germany, 6Rheumatology/Immunology, Medizinische Klinik II, Universitätsklinik, Würzburg, Germany

    Background/Purpose: Patients with psoriatic arthritis (PsA) or ankylosing spondylitis (AS) may suffer from extraarticular (EA) manifestations (uveitis, psoriasis) and have higher rates of comorbidities like…
  • Abstract Number: 929 • 2018 ACR/ARHP Annual Meeting

    Transcriptional Profiling of the Subcutaneous Rheumatoid Nodule: An Insight into Pathogenic Mechanisms and Cellular Content

    Judith Marsman1, Melanie J Millier1, John Highton1, Lisa K. Stamp2 and Paul A Hessian1, 1Department of Medicine, University of Otago, Dunedin, New Zealand, 2University of Otago, Christchurch, New Zealand

    Background/Purpose: Rheumatoid nodules are the most common cutaneous manifestation in patients with RA, often associated with longstanding and a more severe disease course. Paradoxically, therapy…
  • Abstract Number: 1593 • 2018 ACR/ARHP Annual Meeting

    Extra-Articular Manifestations, Neoplasms and Cardiovascular Events in a Series of Spondyloarthritis from a Single Center

    Itziar Calvo Zorrilla1, Edurne Guerrero Basterretxea1, Oihane Ibarguengoitia1, David Montero1, Maria Luz Garcia Vivar1, Esther Ruíz Lucea2, Ignacio Torre Salaberri2, Olaia Begoña Fernandez Berrizbeitia2, Juan Maria Blanco Madrigal2, Ana Rosa Inchaurbe Pellejero1, Clara Eugenia Perez Velasquez2, Natalia Rivera-García3, Maria Jesus Allande Lopez Linares3, Iñigo Gorostiza-Hormaetxe4 and Eva Galíndez Agirregoikoa2, 1Rheumatology, Rheumatology Department; Basurto University Hospital, Bilbao, Spain, 2Rheumatology Department; Basurto University Hospital, Bilbao, Spain, 3Rheumatology, University Hospital of Basurto, Bilbao, Spain, 4Research Department, Basurto University Hospital, Bilbao, Spain

    Background/Purpose: Spondyloarthritis(SpA) is characterized by axial, peripheral and extra-articular manifestation(EAMs). Its frequency depends on the series, being the psoriasis(Ps), uveitis and inflammatory bowel disease(IBD) the…
  • Abstract Number: 1631 • 2018 ACR/ARHP Annual Meeting

    Incidence of Uveitis in Patients with Spondyloarthritis: The Impact of Biologics Era.a Multicenter Study Using Data from International ASAS-Comospa Study

    Hernán Maldonado Ficco1, Rodolfo Perez-Alamino2, Christian A. Waimann3, José A. Maldonado-Cocco4, Anna Moltó5, Maxime Dougados6, Robert B.M. Landewé7, Désirée van der Heijde8 and Filip van Den Bosch9, 1Rheumatology Section, Hospital San Antonio de Padua, Río Cuarto- Córdoba, Argentina, 2Rheumatology Department, Hospital de Clínicas Pte. Dr. Nicolás Avellaneda, Tucumán, Argentina, 3Hospital Dr. Hector Cura, Olavarria, Argentina, 4Buenos Aires University, University of Buenos Aires School of Medicine. Argentina, Buenos Aires, Argentina, 5Rheumatology Department, Hôpital Cochin, AP-HP, Paris, France, 6Hopital Cochin, Paris, France, 7Amsterdam Rheumatology & Clinical Immunology Center and Zuyderland Medical Center, Amsterdam; Heerlen, Netherlands, 8Leiden University Medical Center, Leiden, Leiden, Netherlands, 9Department of Rheumatology, University of Ghent, Ghent, Belgium, Ghent, Belgium

    Background/Purpose: Uveitis is a common extra-articular manifestation in Spondyloarthritis (SpA). The purpose of this study was to analyze incidence of uveitis in SpA patients during…
  • Abstract Number: 1638 • 2018 ACR/ARHP Annual Meeting

    Impact of Extra-Articular Manifestations on Patient-Reported Outcomes in Ankylosing Spondylitis and Psoriatic Arthritis: Interim Results from the Complete Studies

    Louis Bessette1, Majed Khraishi2,3, Brandusa Florica4, Yatish Setty5, Michelle Teo6 and Valencia P. Remple7, 1Centre Hospitalier de l'Université Laval, Quebec, QC, Canada, 2Memorial University of Newfoundland, St. John's, NF, Canada, 3Nexus Clinical Research, Memorial University of Newfoundland, St Johns, NF, Canada, 4University of Toronto, Toronto, ON, Canada, 5Grey Bruce Health Services, Owen Sound, ON, Canada, 6University of British Columbia, Penticton, BC, Canada, 7AbbVie Corporation, Montreal, QC, Canada

    Background/Purpose: Extra-articular manifestations (EAMs) in rheumatic diseases have been previously found to negatively impact health outcomes including quality of life and work capacity. Even though…
  • Abstract Number: 2506 • 2018 ACR/ARHP Annual Meeting

    The Joint Disease Burden in Patients with Secondary Sjögren’s Syndrome and RA Compared to Patients with RA Only

    Evo Alemao1, Yogesh Saini2, Ying Bao1, Aarti Rao2, Christine K Iannaccone3, Michael E Weinblatt3 and Nancy A. Shadick3, 1Bristol-Myers Squibb, Princeton, NJ, 2Mu Sigma, Bangalore, India, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Secondary Sjögren’s syndrome (sSS) is considered a poor prognostic factor in RA and is a common extra-articular manifestation of RA. We estimated prevalence of…
  • Abstract Number: 2520 • 2017 ACR/ARHP Annual Meeting

    Incidence of Extra-Articular Manifestations in Psa and As Patients Treated with Golimumab in Canadian Real-World

    Michelle Teo1, Derek Haaland2, John Kelsall3, Isabelle Fortin4, Pauline Boulos5, Raman Rai6, Sanjay Dixit7, B Haraoui8, Dalton Sholter9, Eliofotisti Psaradellis10, Emmanouil Rampakakis10, Brendan Osborne11, Francois Nantel11 and Allen J Lehman12, 1Balfour Medical Clinic, Penticton, BC, Canada, 2Rheumatology, Clinical Immunology & Allergy, McMaster University, Barrie, ON, Canada, 3Rheumatology, University of British Columbia, Vancouver, BC, Canada, 4Centre de Rhumatologie De l’Est du Quebec, Rimouski, QC, Canada, 5Rheumatology, McMaster University, Hamilton, ON, Canada, 6Private Practice, Hamilton, ON, Canada, 7Rheumatology, McMaster University Hamilton, Burlington, ON, Canada, 8Institut de Recherche en Rhumatologie de Montréal (IRRM), Montreal, QC, Canada, 9Rheumatology Associates, Edmonton, AB, Canada, 10JSS Medical Research, Montreal, QC, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada, 12Janssen Inc., Toronto, ON, Canada

    Background/Purpose: Spondyloarthropathies (SpA) encompass a heterogeneous group of chronic inflammatory diseases affecting axial and peripheral joints. Besides articular symptoms, patients also experience extra-articular manifestations (EAMs)…
  • Abstract Number: 1355 • 2016 ACR/ARHP Annual Meeting

    ASAH1 Gene Mutations Cause Acid Ceramidase Deficiency (Farber Disease), with Symptoms Including Arthritis and Subcutaneous Nodules. Patients Are Often Misdiagnosed with JIA, and Slowly Progressive Disease May Only be Diagnosed in Adulthood

    Alexander Solyom1, Calogera Simonaro2 and Edward Schuchman3, 1Roivant Sciences, New York, NY, 2Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 3Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: Mutations in the ASAH1 gene cause acid ceramidase deficiency, accumulation of the pro-inflammatory and pro-apoptotic lipid ceramide, and a distinct set of clinical features,…
  • Abstract Number: 1486 • 2016 ACR/ARHP Annual Meeting

    Associations Between Heart Rate Adjusted ST Segment and Heart Rate Variability in Patients with Rheumatoid Arthritis

    Ahmad Osailan1,2, Jet JJCS Veldhuijzen van Zanten2,3, Joan Duda1, Sally Fenton1,2, Peter Rouse4, Nikos Ntoumanis5, George D. Kitas1,2 and George Metsios2,6, 1School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, 2Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, 3School of Sport, Exercise and Rehabilitation, University of Birmingham, Dudley, United Kingdom, 4Department for Health, University of Bath, Bath, United Kingdom, 5School of Psychology & Speech Pathology, Curtin University, Perth, Australia, 6Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom

    Background/Purpose:  Patients with rheumatoid arthritis (RA) are at increased risk for myocardial infarction (MI), which is often silent. Heart rate adjusted ST segment (ST/HR index)…
  • Abstract Number: 1724 • 2016 ACR/ARHP Annual Meeting

    The Effect of Certolizumab Pegol on Skin Manifestations of Psoriatic Arthritis over 4 Years of Treatment

    Majed Khraishi1, Alice B. Gottlieb2, Bengt Hoepken3, Luke Peterson4 and Philip J. Mease5, 1Department of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2Tufts University School of Medicine, Boston, MA, 3UCB Pharma, Monheim, Germany, 4UCB Pharma, Raleigh, NC, 5Swedish Medical Center and University of Washington, Seattle, WA

    Background/Purpose: The majority of patients (pts) with psoriatic arthritis (PsA) experience psoriatic skin manifestations, which add to the already high burden of disease. The RAPID-PsA…
  • Abstract Number: 2879 • 2015 ACR/ARHP Annual Meeting

    What Is the Location of Dactylitis in Ankylosing Spondylitis and Psoriatic Arthritis Patients and How Do They Respond to Anti-TNF Treatment?

    Regan Arendse1, Proton Rahman2, Denis Choquette3, J Antonio Avina-Zubieta4, Michel Zummer5, Milton F. Baker6, Jacqueline Stewart7, Isabelle Fortin8, Michelle Teo9, Emmanouil Rampakakis10, Eliofotisti Psaradellis11, Brendan Osborne12, Cathy Tkaczyk12, Karina Maslova13, Francois Nantel14 and Allen J Lehman13, 1University of Saskatchewan, Saskatoon, SK, Canada, 2Computer Sciences, Memorial University of Newfoundland, St. John's, NF, Canada, 3Rheumatology Department, Institut de Rhumatologie de Montréal and University of Montreal, Montreal, QC, Canada, 4Medicine, University of British Columbia, Department of Medicine, Division of Rheumatology, Vancouver, BC, Canada, 5Rheumatology, Hôpital Maisonneuve-Rosemont and University of Montreal, Montreal, QC, Canada, 6VIHA, Victoria, BC, Canada, 7Penticton Regional Hospital, Penticton, BC, Canada, 8Centre de Rhumatologie de l'Est du Québec, Rimouski, QC, Canada, 9Rheumatology, Penticton Regional Hospital, Penticton, BC, Canada, 10JSS Medical Research, St-Laurent, QC, Canada, 11JSS Medical Research, Montreal, QC, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada, 13Janssen Inc., Toronto, ON, Canada, 1419 Green belt Dr, Janssen Inc., Toronto, ON, Canada

    Background/Purpose: Dactylitis is one of the most commonly reported features in spondyloarthritis. It has been hypothesized that dactylitis is a functional enthesitis at the proximal…
  • Abstract Number: 1613 • 2015 ACR/ARHP Annual Meeting

    Expression of the Genes Facilitating Methotrexate Action within Rheumatoid Subcutaneous Nodules

    Emma Houlder1, Melanie Millier2, John Highton3, Lisa K. Stamp4 and Paul Hessian2, 1Medicine, University of Otago, Dunedin, New Zealand, 2Department of Medicine, University of Otago, Dunedin, New Zealand, 3Dept of Medicine, University of Otago, Dunedin, New Zealand, 4Medicine, University of Otago, Christchurch, Christchurch, New Zealand

    Background/Purpose: Methotrexate (MTX) is the most frequently used DMARD in the treatment of rheumatoid arthritis (RA). There are known links between the use of MTX…
  • Abstract Number: 1590 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis-Related Interstitial Lung Disease (RA-ILD): Methotrexate and the Extension of Lung Disease Are Associated to Prognosis

    Jorge Rojas-Serrano1, Denisse Herrera-Bringas2, Renzo Perez-Dorame3, Mayra Mejia2 and Heidegger Mateos-Toledo4, 1Interstitial Lung Diseases Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico, 2Interstitial Lung Diseases Unit, Insituto Nacional de Enfermedades Respiratorias, Mexico, Mexico, 3Intertitial Lung Disease Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico, Mexico, 4Interstitial Lung Diseases Unit, Instituto Nacional de Enfermedades Respiratorias, Mexico, Mexico

    Background/Purpose:Interstitial lung disease (ILD) is a severe rheumatoid arthritis manifestation with a median survival of 2.6 years. Worst survival has been associated to usual interstitial…
  • Abstract Number: 1566 • 2015 ACR/ARHP Annual Meeting

    The Impact of Severe Extra-Articular Manifestations and Patient Reported Outcome Measures on Cardiovascular Disease in Rheumatoid Arthritis

    Lisa Theander1, Jan-Åke Nilsson1, Minna Willim1,2, Britt-Marie Nyhäll-Wåhlin1,3, Lennart T.H. Jacobsson1,4 and Carl Turesson1,5, 1Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 2Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, 3Department of Rheumatology, Falun Hospital, Falun, Sweden, 4Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, 5Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular disease (CVD). Disease severity, including extra-articular rheumatoid arthritis (ExRA) manifestations, has previously been demonstrated…
  • Abstract Number: 1562 • 2015 ACR/ARHP Annual Meeting

    Clinical Correlates, Outcomes and Predictors of Episcleritis and Scleritis Associated with Rheumatoid Arthritis

    Cristian Caimmi1, Wendy M. Smith2, Cynthia S. Crowson3, Eric L. Matteson4 and Ashima Makol5, 1Unit of Rheumatology, Department of Medicine,, University of Verona, Verona, Italy, 2Department of Ophthalmology, Mayo Clinic, Rochester, MN, 3Division of Rheumatology and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN

    Background/Purpose: Inflammatory ocular disease (IOD) has traditionally been regarded as a severe extra-articular manifestation of rheumatoid arthritis (RA) with high mortality. This study aims to…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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