Abstracts tagged "Epidemiology"

Abstract Number: 2679 • ACR Convergence 2025
Early-Life Nutrition and Gene-Environment Interactions Influencing Juvenile Idiopathic Arthritis Risk: Results from a Pregnancy Cohort
Vilde Øverlien Dåstøl¹, Ida Henriette Caspersen², Kristine Løkås Haftorn³, Sigrid Hestetun⁴, Siri Eldevik Håberg⁵, Karen H. Costenbader⁶, Marin Strøm⁷, Sjurdur Frodi Olsen⁸, Anne Lise Brantsæter⁹, Ketil Størdal¹⁰ and Helga Sanner¹, ¹Oslo University Hospital, Oslo, Norway, ²Norwegian Institute of Public Health, Centre for Fertility and Health/Oslo University Hospital, Oslo, Norway, ³Oslo University Hospital, Department of Rheumatology, Oslo, Norway, ⁴Oslo University Hospital, Department of Rheumatology/University of Oslo, Oslo, Norway, ⁵Norwegian Institute of Public Health, Centre for Fertility and Health/University of Bergen, Oslo, Norway, ⁶Harvard Medical School and Brigham and Women's Hospital, Boston, MA, ⁷Statens Serum Institut, Department of Epidemiology Research, Copenhagen, Denmark, ⁸Statens Serum Institut,Biobank, congenital disorders, and vaccines preparedness/Harvard T.H. Chan School of Public Health, Copenhagen, Denmark, ⁹Norwegian Institute of Public Health, Department of Food Safety and Centre for Sustainable Diets, Oslo, Norway, ¹⁰Oslo University Hospital, Department of Pediatric and Adolescent Medicine/University of Oslo, Oslo, Norway
Background/Purpose: Early-life nutrition may influence the risk of immune-mediated diseases like juvenile idiopathic arthritis (JIA). The benefits of breastfeeding are well established, but findings related…
Abstract Number: 2270 • ACR Convergence 2025
ACKR1 and Leukopenia in Patients with Rheumatoid Arthritis Treated with Disease Modifying Antirheumatic Drugs
Daniela Chavez de Paz Solis¹, Puran Nepa², Laura Daniel³, Yan Guo⁴, Jonathan Mosley⁵, Michael Stein⁶ and Cecilia Chung⁴, ¹University of Maine, Caribou, ME, ²University of Miami, Research Service, Miami VA Healthcare System, Miami, FL, ³University of Miami, Nashville, TN, ⁴University of Miami, Miami, ⁵UT Southwestern Medical Center, Dallas, ⁶Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Disease-modifying antirheumatic drugs (DMARDs) such as methotrexate, sulfasalazine, and leflunomide arecommonly prescribed for RA treatment but carry the risk of leukopenia. The ACKR1 promoter…
Abstract Number: 1909 • ACR Convergence 2025
Trends of venous thromboembolism after total joint replacement in the United Kingdom after the introduction of NICE guidelines.
Subhashisa Swain¹, Nadja Leith², Sarah Brown², Cynthia Wright Drakesmith², Jonathan Rees³, Clare Bankhead⁴ and John Powell⁴, ¹Keele University, University of Oxford, Keele, United Kingdom, ²University of Oxford, Oxford, United Kingdom, ³NDORMS, University of Oxford, Oxford, United Kingdom, ⁴NDPCHS, University of Oxford, Oxford, United Kingdom
Background/Purpose: Joint replacement (JR) surgery is one of the preferred management for end-stage arthritis. Venous Thromboembolism (VTE) is one of the major post-surgical complications after…
Abstract Number: 1883 • ACR Convergence 2025
Temporal Patterns of Cardiometabolic Comorbidities Before and After Psoriatic Arthritis Diagnosis: A Nationwide Retrospective Study from Poland.
Batko Bogdan¹, Mateusz Szeląg², Krzysztof Batko³, Magdalena Krajewska-Włodarczyk⁴, Zbigniew Żuber⁵, Marcin Stajszczyk⁶, Brygida Kwiatkowska⁷ and Tomasz Guzik⁸, ¹Department of Rheumatology and Immunology, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski University, Krakow, Poland, Kraków, Poland, ²Ministry of Health, Warsaw, Poland, ³Department of Dermatology, University Hospital in Krakow, Poland, Krakow, Poland, ⁴University of Warmia & Mazury, Olsztyn, Poland, ⁵Department of Pediatrics, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski University, Krakow, Poland, Krakow, Poland, ⁶Department of Rheumatology and Autoimmune Diseases, Silesian Center for Rheumatology, Orthopedics and Rehabilitation, Ustroń, Poland, Ustron, Poland, ⁷Clinic of Early Arthritis, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland, Warsaw, Poland, ⁸BHF Centre for Research Excellence, Centre for Cardiovascular Sciences, The University of Edin-burgh, Edinburgh, UK, Edinburgh, United Kingdom
Background/Purpose: While the association between psoriatic arthritis (PsA) and cardiometabolic disorders is established, the temporal sequence and progression of these comorbidities remain poorly characterized. To…
Abstract Number: 1500 • ACR Convergence 2025
Prognostic Impact of Thrombocytopenia on Morbidity and Mortality in Systemic Lupus Erythematosus: A Retrospective Single-Center Study
Milad Heydari-Kamjani¹, Amir Daneshvar², Dana Nachawati², Elleson Harper², Keri Ann Pfeil², Meghan Gump², Lindsay Frumker³ and Omer Pamuk¹, ¹University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, ²University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, ³University hospitals Cleveland medical center, Highland Heights, OH
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with heterogeneous hematologic manifestations. Thrombocytopenia (TP) in SLE may be associated with major organ involvement…
Abstract Number: 1247 • ACR Convergence 2025
Relation of Measures of Pain Sensitization to Widespread Pain
ZHIQIANG WANG¹, Sarah Tilley², Laura Frey Law³, Cora Lewis⁴, Michael Nevitt⁵, Kosaku Aoyagi⁶, Chunyi Wen⁷, Changhai Ding¹ and Tuhina Neogi⁸, ¹Zhujiang Hospital, Southern Medical University, Guangzhou, China (People's Republic), ²Boston University School of Medicine, Somerville, MA, ³Department of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, Iowa City, IA, ⁴The University of Alabama at Birmingham, Birmingham, AL, ⁵University of California, San Francisco, San Francisco, CA, ⁶University of Texas at El Paso, El Paso, TX, ⁷The Hong Kong Polytechnic University, Hong Kong, China (People's Republic), ⁸Boston University School of Medicine, Boston, MA
Background/Purpose: Widespread pain (WSP) is thought to be related to alterations in nociceptive signaling such as pain sensitization. Whether pain sensitization predisposes to an increase…
Abstract Number: 1015 • ACR Convergence 2025
Refining Administrative Algorithms For Accurate Identification of Patients with Systemic Sclerosis In Trinetx Research Network
Gulsen Ozen¹, Michael O'Rorke², Paul Romitti² and Robyn Domsic³, ¹University of Iowa, Carver College of Medicine, Division of Immunology, Coralville, IA, ²University of Iowa College of Public Health, Department of Epidemiology, Iowa City, IA, ³University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Large data-driven medical research is invaluable in answering questions about epidemiology, genetics, therapeutics, and outcomes of rare diseases. Systemic sclerosis (SSc) is rare yet…
Abstract Number: 0728 • ACR Convergence 2025
Incidence and Clinical Characteristics of ANCA-Associated Vasculitis: A Nationwide Study in Spain
Susana Romero-Yuste¹, Marta Domínguez-Álvaro², Antonio Fernández-Nebro³, Miquel Blasco⁴, Beatriz Ventosa⁵, Javier Narváez⁶, Gema Fernández⁷, Iñigo Rúa-Figueroa⁸, Desirée Luis-Rodríguez⁹ and Manuel Macía¹⁰, ¹University Hospital Complex of Pontevedra, Pontevedra, Spain, ²Sociedad Española de Reumatología, Madrid, Spain, ³Hospital Regional Universitario de Malaga, Malaga, Spain, Malaga, Spain, ⁴Hospital clinic Barcelona, Barcelona Spain, Spain, ⁵Spanish Society of Rheumatology, Madrid, Spain, ⁶Hospital Universitario de Bellvitge, Barcelona, Spain, ⁷Hospital la Paz, Madrid, Madrid, Spain, ⁸Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain, ⁹Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain, ¹⁰Hospital Universitario Nuestra Señora de Candelaria,, Tenerife, Spain
Background/Purpose: ANCA-associated vasculitides (AAV)—granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA)are rare but severe systemic vasculitides with significant morbidity and…
Abstract Number: 0245 • ACR Convergence 2025
Predictors of Arterial Stiffness in Connective Tissue Diseases: Insights from the Lupus Extended Autoimmune Phenotype (LEAP) Cohort Study
cristiana Sieiro¹, Sarah Dyball², Ellen Bruce³, Ben Parker⁴ and Ian Bruce⁵, ¹Univrsity of Manchester, Manchester, United Kingdom, ²University of Manchester, Manchester, United Kingdom, ³Manchester University NHS FT, The Kellgren Centre of Rheumatology, Manchester, United Kingdom, Manchester, ⁴NIHR Manchester CRF, Manchester Royal Infirmary, Manchester, United Kingdom, ⁵Centre for Public Health, Faculty of Medicine, Health and Life Sciences, Queen's University, Belfast, Manchester, United Kingdom
Background/Purpose: Connective tissue diseases (CTDs), including systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and Sjögren’s disease (SjD), are associated with an increased risk of cardiovascular…
Abstract Number: 2661 • ACR Convergence 2025
Heterogeneity of RA-ILD by Longitudinal Forced Vital Capacity Measurements Is Associated with Survival and Respiratory Hospitalization
Bryant England¹, Yangyuna Yang¹, Punyasha Roul², Tate Johnson¹, Scott Matson³, Grant Cannon⁴, Brian Sauer⁵, Jeffrey Curtis⁶, Joshua Baker⁷ and Ted Mikuls¹, ¹University of Nebraska Medical Center, Omaha, NE, ²UNMC, Omaha, NE, ³University of Kansas, Kansas City, MO, ⁴University of Utah and Salt Lake City VA, Salt Lake City, UT, ⁵Salt Lake City VA/University of Utah, Salt Lake City, UT, ⁶Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, ⁷University of Pennsylvania, Philadelphia, PA
Background/Purpose: Forced vital capacity (FVC) is one of the primary disease measures monitored in RA-associated interstitial lung disease (RA-ILD). While prior studies have suggested a…
Abstract Number: 2221 • ACR Convergence 2025
Racial Differences in Cardiovascular Events and Adverse Pregnancy Outcomes Among Pregnant Individuals With Systemic Lupus Erythematosus
Rashmi Dhital¹, Rebecca Baer² and Christina Chambers³, ¹Vanderbilt University Medical Center, Brentwood, TN, ²University of California San Diego, San Diego, CA, ³University of California, San Diego, La Jolla, CA
Background/Purpose: Pregnant individuals with systemic lupus erythematosus (SLE) face an increased risk of cardiovascular events (CVEs) as well as adverse pregnancy outcomes (APOs). While racial…
Abstract Number: 1908 • ACR Convergence 2025
Clinical and Imaging Features of Haemochromatosis Arthropathy – a Systematic Literature Review and Meta- Analysis
Svenja Engelhardt¹, Sabine Buroh², Guido Schwarzer³, Andreas Kerschbaumer⁴, Axel Braner⁵, Mathilde Herber⁶, Pedro Machado⁷, Patrick Kiely⁸ and Stephanie Finzel⁹, ¹University of Freiburg, Freiburg im Breisgau, Germany, ²Library of the Medical Center - University of Freiburg, Faculty of Medicine, Library of the Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany, ³University of Freiburg, Freiburg, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany, Freiburg, Germany, Freiburg, Germany, ⁴Stanford University / Medical University of Vienna, Stanford, CA, ⁵MVZ Aschaffenburg, Aschaffenburg, Germany, Frankfurt, Germany, ⁶Strasbourg Centre University, Strasbourg, France, Department of Internal Medicine, Strasbourg, France, Strasbourg, France, ⁷Department of Rheumatology, University College London, and Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ⁸St George's University Hospitals NHS Foundation Trust, London, United Kingdom, ⁹Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Background/Purpose: Haemochromatosis arthropathy (HA) has been little researched to date. Arthropathy frequently is amongst thefirst clinical manifestations of haemochromatosis, but might be overlooked or misdiagnosed…
Abstract Number: 1882 • ACR Convergence 2025
Vessels Under Fire: National Mortality Trends in Systemic Vasculitides in the United States, 1999–2020
Aziz-ur-Rahman Khalid¹, Ghassan Makhoul², Hasan Munshi², Islam Rajab², Emmanuel Olumuyide³, MD Walid Akram Hussain², Ahmed Huzien² and Robert Lahita⁴, ¹St. Joseph's University Medical Center, wayne, ²St. Josephs University Medical Center, Paterson, ³Advocate Illinois Masonic Medical Center, Chicago, ⁴St. Josephs University Medical Center, Wayne, NJ
Background/Purpose: Systemic vasculitides are rare but potentially life-threatening inflammatory disorders affecting blood vessels. Despite therapeutic advances, national mortality trends across vasculitis subtypes remain poorly defined.…
Abstract Number: 1429 • ACR Convergence 2025
Survival Outcomes in Elderly Patients with Axial Spondyloarthritis and Concomitant Cancer
Savannah Bowman¹, Mei Li², Xiudong Lei³, Hui Zhao³, Juan Ruiz⁴, Sharon H. Giordano³, Alexis Ogdie⁵ and Maria Suarez-Almazor⁶, ¹Baylor College of Medicine, Houston, ²The University of Texas Health Science Center at Houston, Houston, ³The University of Texas MD Anderson Cancer Center, Houston, ⁴Hospital Alemán, Buenos Aires, Argentina, ⁵University of Pennsylvania, Philadelphia, PA, ⁶MD Anderson Cancer Center, Houston, TX
Background/Purpose: Axial spondyloarthritis (axSpA) is associated with several comorbidities, including cancer. Prior studies have shown that elderly patients with rheumatoid arthritis and concomitant breast or…
Abstract Number: 1190 • ACR Convergence 2025
IgG4-related disease with comorbid autoimmune diseases: a retrospective study from a large cohort
Xinli Yang¹, Wen Zhang², Jiaxin zhou³ and Yuxue Nie⁴, ¹Peking Union Medical College, Dong Cheng Qu, China (People's Republic), ²Peking Union Medical College Hospital, Dong Cheng Qu, China (People's Republic), ³Peking Union Medical College Hospital, Beijing, China (People's Republic), ⁴Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China, Dong Cheng Qu, China (People's Republic)
Background/Purpose: This study aimed to explore the clinical characteristics, treatment, and prognosis of IgG4-related disease (IgG4-RD) patients with comorbid autoimmune diseases (AIDs).Methods: A total of…

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