Abstracts tagged "Epidemiology"

Abstract Number: 2645 • ACR Convergence 2025
Age-specific Incidence of Systemic Lupus Erythematosus in the United States: A Meta-Analysis of Data from the Centers for Disease Control and Prevention Lupus Registries
Peter Izmirly¹, Elizabeth Ferucci², Aimee Hersh³, Mary Beth Son⁴, Cristina Drenkard⁵, S. Sam Lim⁶, Cynthia Crowson⁷, Ali Duarte-Garcia⁸, Jill Buyon⁹, Heather Gold⁹, Maria Dall'Era¹⁰, Patti Katz¹¹, Laura Plantinga¹², Jinoos Yazdany¹³, Jennifer Reihm¹⁴, Emily Somers¹⁵ and Hilary Parton¹⁶, ¹New York University Grossman School of Medicine, New York, NY, ²Alaska Native Tribal Health Consortium, Anchorage, AK, ³University of Utah, Salt Lake City, UT, ⁴Boston Children's Hospital, Boston, MA, ⁵Rollins School of Public Health, Emory University, Atlanta, Georgia, USA, Acworth, GA, ⁶Emory University School of Medicine, Atlanta, GA, ⁷Mayo Clinic, Stewartvillle, MN, ⁸Mayo Clinic, Rochester, MN, ⁹NYU Grossman School of Medicine, New York, NY, ¹⁰Division of Rheumatology, University of California, San Francisco, CA, ¹¹UCSF, San Rafael, CA, ¹²University of California, San Francisco, San Francisco, CA, ¹³UCSF, San Francisco, CA, ¹⁴University of California, San Francisco, San Francisco, ¹⁵University of Michigan, Ann Arbor, MI, ¹⁶New York City Department of Health and Mental Hygiene, New York
Background/Purpose: Current estimates for age of SLE onset are limited, particularly for males and racial/ethnic groups in the United States. Leveraging five Centers for Disease…
Abstract Number: 2113 • ACR Convergence 2025
Mortality rate in patients with hip fracture: is it recommendable to establish fracture units?
Esther Monleon Acosta¹, Alicia Pérez González², José Andrés Rodríguez Fernández², Pedro José Manuel Hernández², María del Rosario Oliva Ruiz², José María Andreu Ubero², Paloma Valentina Castillo Dayer², Gloria Albaladejo Paredes³, Carlos Fernández Díaz⁴, Angela Egea Fuentes², Montserrat Fernández Salamanca² and Vicente Cogolludo Campillo⁵, ¹Hospital Santa Lucia, Cartagena, Spain, ²Hospital General Universitario Santa Lucia, Cartagena, Spain, ³Hospital General Universitario Santa Lucía, CARTAGENA, Spain, ⁴H.U. Santa Lucia, Murcia, Spain, ⁵Hospital General Universitario Santa Lucia, Santa Lucia, Cartage, Spain
Background/Purpose: Hip fracture is the second most common osteoporotic fracture and the one with the highest socio-economic cost. It is associated with high morbidity and…
Abstract Number: 1906 • ACR Convergence 2025
The incidence and mortality of connective tissue diseases in England: a population-level cohort study from 2012 to 2023
Samir Patel¹, Mark Russell¹, Katie Bechman¹, Maryam Adas¹, Zijing Yang¹, Edward Alveyn¹, Chris Wincup², Alexandru Dregan¹, Kate Bramham¹, Sam Norton¹, James Galloway¹ and Patrick Gordon¹, ¹King's College London, London, United Kingdom, ²King's College Hospital, London, United Kingdom
Background/Purpose: The reported incidence and mortality of connective tissue diseases (CTDs) in England has been inconsistent in the literature. Our objective was to describe current…
Abstract Number: 1880 • ACR Convergence 2025
Rheumatoid Arthritis Mortality in the U.S. (1999–2020): A Decline in Rates, But Not in Disparities
Aziz-ur-Rahman Khalid¹, Ghassan Makhoul², Hasan Munshi², Islam Rajab², Emmanuel Olumuyide³, MD Walid Akram Hussain², Aqsa Sorathia², Elvira Assaf², Amer Al Badawy², John Salama² and Robert Lahita⁴, ¹St. Joseph's University Medical Center, wayne, ²St. Josephs University Medical Center, Paterson, ³Advocate Illinois Masonic Medical Center, Chicago, ⁴St. Josephs University Medical Center, Wayne, NJ
Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease associated with increased morbidity and mortality. While treatments have evolved, national trends and sociodemographic disparities in…
Abstract Number: 1394 • ACR Convergence 2025
Burden of Comorbidities Across EULAR Sjögren’s Syndrome Disease Activity Index (ESSDAI) Domains: Treatment Prevalence Among Commercially Insured Sjögren’s Patients in the United States
Minoti Ganguli, Annie Kilby, Ahva Shahabi and Tsu-Chieh Jay Lin, Amgen Inc., Thousand Oaks, CA
Background/Purpose: Sjögren’s disease (SjD) is a systemic disorder characterized by exocrine gland inflammation, leading to dry eyes/mouth, and multiple organ systems involvement1. The European League…
Abstract Number: 1099 • ACR Convergence 2025
Safety and Effectiveness of Hydroxychloroquine in the Treatment of Rheumatic Immune-Related Adverse Events
Grace Haeun Lee¹, Gregory Challener², Janeth Yinh³, Jeffrey Sparks⁴, Kerry L. Reynolds⁵, Donald P. Lawrence⁵, Meghan J. Mooradian⁵, Ryan J. Sullivan⁵, Hyon K. Choi⁶ and Minna Kohler⁷, ¹Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ²Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, ³Massachusetts General Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston, MA, ⁵Massachusetts General Hospital, Boston, ⁶MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, ⁷Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Hydroxychloroquine (HCQ) has been recommended [1-3] as a steroid-sparing agent for immune checkpoint inhibitor-inflammatory arthritis (ICI-IA), preferred due to its low immunosuppressive effect. However,…
Abstract Number: 1009 • ACR Convergence 2025
Pregnancy Outcomes and Comorbidities Among Individuals with Systemic Lupus Erythematosus: A Nationwide Study Using Publicly Funded Health Insurance Claims Data
Amadeia Rector¹, Sadaf Sediqi², Alyssa Howren² and Julia F Simard³, ¹Stanford University, San Francisco, CA, ²Stanford University, Palo Alto, CA, ³Stanford Medicine, Stanford, CA
Background/Purpose: Individuals with SLE are at increased risk for pregnancy complications such as preeclampsia and preterm delivery. As SLE is commonly diagnosed and active during…
Abstract Number: 0522 • ACR Convergence 2025
The Incidence Rate and Risk Factors of Arrhythmias in Patients with Psoriatic Arthritis
Abdulrahman Y Almansouri¹, Jiayi Li², Ali Alhadri³, Keith Colaco⁴, Paula Harvey⁵, Shadi Ahktari⁶, Vinod Chandran⁷, Dafna D. Gladman⁸, Richard Cook² and Lihi Eder⁷, ¹King Faisal Specialist Hospital and Research Centre, University of Toronto and Women's College Hospital, Toronto, Canada, ²University of Waterloo, Waterloo, Canada, ³King Fahad Hospital, University of Toronto and Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, Canada, ⁴University of Toronto, Toronto, Canada, ⁵University of Toronto Department of Medicine and Women's College Hospital, Toronto, ON, Canada, ⁶University of Toronto Department of Medicine and Women's College Hospital, Toronto, Canada, ⁷University of Toronto, Toronto, ON, Canada, ⁸Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada
Background/Purpose: Patients with psoriatic arthritis (PsA) are at increased risk of developing cardiovascular diseases, including arrhythmias. Given that traditional cardiovascular disease risk factors are prevalent…
Abstract Number: 0161 • ACR Convergence 2025
Risk Factors and Clinical Predictors of Lung Cancer in Systemic Sclerosis: A Matched Case-Control Study from a Michigan Cohort
Madiha Naqsh Siddiqui¹, Yen Chen¹, Rosemary Gedert², Suiyuan Huang², Dinesh Khanna² and John Varga², ¹University of Michigan, Ann Arbor, ²University of Michigan, Ann Arbor, MI
Background/Purpose: Malignancies are one of the leading causes of non-systemic sclerosis-related mortality in patients with systemic sclerosis (SSc)1, with lung cancer being the most common…
Abstract Number: 2633 • ACR Convergence 2025
Comparative 3-year Safety Outcomes in Patients with Ankylosing Spondylitis Initiating JAK Inhibitor or TNF Inhibitor Therapy
Hsin-Hua Chen, Taichung Veterans General Hospital, Taichung, Taiwan (Republic of China)
Background/Purpose: To compare safety outcomes in patients with ankylosing spondylitis (AS) initiating Janus kinase inhibitors (JAKi) versus tumor necrosis factor inhibitors (TNFi).Methods: This retrospective cohort…
Abstract Number: 2118 • ACR Convergence 2025
Risks of Fracture in Current and Previous Anticonvulsant Users, An Observational Study
Grace Hyeyeon Lee¹, Hamzah Amin² and marwan Bukhari¹, ¹University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom, ²Lancaster University, Lancaster, United Kingdom
Background/Purpose: Anticonvulsants are commonly used to manage neurological and psychiatric disorders such as epilepsy, migraines and bipolar disorder. These medications are often prescribed long-term, and…
Abstract Number: 1905 • ACR Convergence 2025
Exploring the Association Between Environmental Quality Index and Rheumatoid Arthritis Mortality in the United States
Rohan Sharma¹, Eric Yen² and Ram Singh³, ¹UCLA, Bakersfield, CA, ²UCLA, Los Angeles, CA, ³UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Environmental factors such as smoking, pollutants, diet, and geography as well as sex, race/ethnicity, and genetics have been linked with rheumatoid arthritis (RA) pathogenesis…
Abstract Number: 1879 • ACR Convergence 2025
Infections in Hospitalized Patients With and Without Psoriatic Arthritis (2016–2021): A National Inpatient Sample Study
Ayema Haque, Ana Salas, Bruna Diniz, Harshank Patel and Philip Kroth, Western Michigan University School of Medicine, Kalamazoo, MI
Background/Purpose: Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory disorder affecting up to 30% of psoriasis patients and is associated with increased infection risk. This…
Abstract Number: 1393 • ACR Convergence 2025
Prevalence of Sjögren’s Disease in the United States – A Retrospective Cohort Study Among a Commercially Insured Population (2019-2023)
Minoti Ganguli, Annie Kilby, Ahva Shahabi and Tsu-Chieh Jay Lin, Amgen Inc., Thousand Oaks, CA
Background/Purpose: Sjögren’s disease (SjD) is a systemic autoimmune condition characterized by diverse clinical manifestations, which often complicates diagnosis and disease management1. Previous epidemiological estimates of…
Abstract Number: 1087 • ACR Convergence 2025
Impact of Neighborhood-Level Social Vulnerability on Disease Severity, Clinical Manifestations, and Early Mortality in Systemic Lupus Erythematosus
Zoe Reed¹, Catriona Wagner², Xana Howard¹, Alexandre Cammarata-Mouchtouris¹, Study Team ALE⁰⁶ Clinical¹, Wade DeJager³ and Judith James¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Santa Cruz, CA, ³Oklahoma Medical Research Foundation, Oklahoma City
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with considerable clinical and molecular heterogeneity. Significant disparities exist in SLE, with minority populations experiencing…

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