Abstracts tagged "Epidemiology"

Abstract Number: 0898 • ACR Convergence 2022
Risk of Aortic Stenosis and Undergoing Aortic Valve Replacement in Rheumatoid Arthritis: An Underrecognized Cardiovascular Complication
Tate Johnson¹, Yangyuna Yang², Chetaj Mahabir², Andrew Goldsweig², Punyasha Roul³, Joshua Baker⁴, Brian Sauer⁵, Grant Cannon⁶, Ted Mikuls⁷ and Bryant England², ¹University of Nebraska Medical Center, Elkhorn, NE, ²University of Nebraska Medical Center, Omaha, NE, ³UNMC, Omaha, NE, ⁴University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA/University of Utah, Salt Lake City, UT, ⁶Retired, Salt Lake City, UT, ⁷Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Valvular carditis is reported as a rare extra-articular manifestation of rheumatoid arthritis (RA). In animal models with coexistent inflammatory arthritis, pro-inflammatory infiltrates of T…
Abstract Number: 1206 • ACR Convergence 2022
Association Between Different Alcoholic Beverages and Serum Urate Level: A Cross-Sectional Study Using Large Medical Checkup Data
Sho Fukui¹, Masato Okada², Mahbubur Rahman³, Takehiro Nakai², Hiromichi Tamaki², Hiroki Matsui⁴, Atsushi Shiraishi⁵, Mitsumasa Kishimoto⁶, Hiroshi Hasegawa⁷, Takeaki Matsuda⁷ and Kazuki Yoshida⁸, ¹Kyorin University Hospital, Tokyo, Japan, ²St. Luke's International Hospital, Tokyo, Japan, ³Graduate School of Public Health, St. Luke’s International University, Tokyo, Japan, ⁴Clinical Research Support Office, Kameda Medical Center, Kamogawa, Japan, ⁵Emergency and Trauma Center, Kameda Medical Center, Kamogawa, Japan, ⁶Kyorin University School of Medicine, Yokohama, Japan, ⁷Kyorin University, Tokyo, Japan, ⁸Brigham and Women's Hospital, Boston, MA
Background/Purpose: Alcohol consumption is associated with increased serum urate levels. However, data regarding the differences in the extent of the association between various types of…
Abstract Number: 1471 • ACR Convergence 2022
Trends and Predictors of Hospitalizations Due to Acute Myocardial Infarction in Systemic Lupus Erythematosus Patients
Izza Bazigh¹, Uzair Khan², Achint Patel³, Aaparna Singh³, Neha Ghalib³, Ghazi Farman⁴, Salman Muddassir³, Farrukh Zaidi⁵, Sami Mughni³ and Adam Grunbaum⁶, ¹HCA Florida Oak Hill Hospital, Spring Hill, FL, ²HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Odessa, FL, ³HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Spring Hill, FL, ⁴Rehman Medical College, Spring Hill, FL, ⁵HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Port Richey, FL, ⁶Gulf Coast Rheumatology, Trinity, FL
Background/Purpose: Cardiovascular events occur more frequently and with earlier onset in patients with Systemic Lupus Erythematosus (SLE) compared with healthy individuals. Several studies have concluded…
Abstract Number: 1750 • ACR Convergence 2022
Association Between Appendicitis and the Risk of Systemic Lupus Erythematosus: A Population-based, Case-control Study
Yun-Wen Chen, Taichung Veterans General Hospital, Taichung, Taiwan
Background/Purpose: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by diverse clinical manifestations. The risk factors of SLE included genetic factors and environmental…
Abstract Number: 1912 • ACR Convergence 2022
Associations of Nociceptive Dysfunction with Physical Activity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study
Deepak Kumar¹, Na Wang², Kaveh Torabian¹, Kosaku Aoyagi³, Joshua Stefanik⁴, Laura Frey-Law⁵, Lisa Carlesso⁶, Jeffrey Hausdorff⁷, Eran Gazit⁷, Neil Segal⁸, Cora E. Lewis⁹, Michael Nevitt¹⁰ and Tuhina Neogi², ¹Boston University, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Boston University, Quincy, MA, ⁴Northeastern University, Boston, MA, ⁵University of Iowa, Iowa City, IA, ⁶McMaster University, Hamilton, ON, Canada, ⁷Tel Aviv Suarasky Medical Center, Tel Aviv, Israel, ⁸University of Kansas, Kansas City, KS, ⁹University of Alabama at Birmingham, Birmingham, AL, ¹⁰University of California San Francisco, Orinda, CA
Background/Purpose: Individuals with chronic pain due to knee osteoarthritis (OA) are insufficiently physically active and increasing physical activity is the first line recommendation for management…
Abstract Number: 2275 • ACR Convergence 2022
Three Dose SARS-CoV-2 Vaccination Is Associated with Reduced Risk of Breakthrough COVID-19 During Omicron Wave in Patients with Autoimmune Diseases
Caoilfhionn Connolly¹, Rachel Wallwork¹, Teresa Po-Yu Chiang¹, Mayan Teles¹, Jennifer Alejo¹, Allan Massie², Ami Shah³, Jemima Albayda¹, Lisa Christopher-Stine¹, Dorry Segev², William Werbel¹ and Julie Paik¹, ¹Johns Hopkins University, Baltimore, MD, ²NYU Langone Health, New York, NY, ³Johns Hopkins Rheumatology, Baltimore, MD
Background/Purpose: While SARS-CoV-2 vaccination mitigates the risk of severe COVID-19, vaccinated patients with autoimmune diseases are more susceptible to infection despite vaccination ("breakthrough" COVID-19) and…
Abstract Number: 0459 • ACR Convergence 2022
The Use of Intravenous Methylprednisolone in Patients with Giant Cell Arteritis: A Population-Based Study
Hampus Henningson¹, Björn Hammar², Carl Turesson³ and Aladdin Mohammad¹, ¹Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden, ²Ophthalmology, Department of Clinical Sciences, Lund University, Lund, Sweden, ³Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden
Background/Purpose: Giant cell arteritis (GCA) is the most common vasculitis in the age-group 50 years and older. Cranial involvement is common and can lead to…
Abstract Number: 0711 • ACR Convergence 2022
Improvement in Excess Mortality in Patients with Rheumatoid Arthritis over the Last Two Decades: A Danish Population-based Matched Cohort Study
Bolette Soussi¹, Kirsten Duch¹, René Cordtz¹, Christian Bork², Salome Kristensen¹, Erik Schmidt², Jesper Lindhardsen³ and Lene Dreyer¹, ¹Center of Rheumatic Research Aalborg, Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, ²Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark, ³Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark
Background/Purpose: Results from previous studies investigating mortality trends in patients with rheumatoid arthritis (RA) have been inconsistent, most likely due to varying cohort sizes and…
Abstract Number: 0905 • ACR Convergence 2022
Predicting Disease Activity in Rheumatoid Arthritis Patients Using Machine Learning: Data from the ACR’s RISE Registry
Eren-Ajani Tshimanga¹, Milena Gianfrancesco², Stefanos Giampanis³, Jing Li², Emma Kersey⁴, Jinoos Yazdany⁵, Beau Norgeot⁶, Gabriela Schmajuk⁷ and Zara Izadi⁴, ¹University of California, Berkeley, Berkeley, CA, ²University of California, San Francisco, San Francisco, CA, ³Anthem, San Francisco, ⁴University of California San Francisco, San Francisco, CA, ⁵UCSF, San Francisco, CA, ⁶Anthem, Oakland, CA, ⁷UCSF / SFVA, San Francisco, CA
Background/Purpose: Predicting the trajectory of disease in individuals with RA is difficult, with numerous factors influencing whether a patient may experience higher or lower disease…
Abstract Number: 1208 • ACR Convergence 2022
Development and Validation of a Prognostic Model for Methotrexate Discontinuation with Abnormal Monitoring Blood-test Results: A Cohort Study Using Data from Clinical Practice Research Datalink Gold and Aurum
Georgina Nakafero¹, Matthew J. Grainge¹, Tim Card¹, Maarten W Taal¹, Guruprasad P Aithal¹, Christopher P Fox², Christian Mallen³, Danielle van der Windt³, Richard Riley³ and Abhishek Abhishek¹, ¹University of Nottingham, Nottingham, United Kingdom, ²Nottingham University Hospital NHS Trust, Nottingham, United Kingdom, ³Keele University, Keele, United Kingdom
Background/Purpose: Patients established on long-term low-dose weekly methotrexate treatment undergo 3-monthly monitoring blood-tests to facilitate early detection of drug-related adverse events. Regular testing may not…
Abstract Number: 1475 • ACR Convergence 2022
Epidemiology of Acute Ischemic Stroke in Patients with Systemic Lupus Erythematosus
Uzair Khan¹, Izza Bazigh², Achint Patel³, Aaparna Singh³, Neha Ghalib³, Ghazi Farman⁴, Salman Muddassir³, Farrukh Zaidi⁵, Sami Mughni³ and Adam Grunbaum⁶, ¹HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Odessa, FL, ²HCA Florida Oak Hill Hospital, Spring Hill, FL, ³HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Spring Hill, FL, ⁴Rehman Medical College, Spring Hill, FL, ⁵HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Port Richey, FL, ⁶Gulf Coast Rheumatology, Trinity, FL
Background/Purpose: Vascular events, including cerebrovascular accidents (CVA) occur earlier and more frequently in patients with Systemic Lupus Erythematosus (SLE) compared with healthy individuals. Several studies…
Abstract Number: 1751 • ACR Convergence 2022
Diagnosing the Cardiovascular Risk of VIOXX: A Place for Rofecoxib in Pain Management
Judith Boice, Mark Corrigan and Bradford Sippy, Tremeau Pharmaceuticals, Inc, Concord, MA
Background/Purpose: Traditional NSAIDs (tNSAIDs) are effective in treating arthritis pain but can be limited by GI adverse events and general bleeding related to platelet inhibition.…
Abstract Number: 1919 • ACR Convergence 2022
Underdiagnosis and Undertreatment of Knee Osteoarthritis in Persons with Type 2 Diabetes: A Cross-sectional Study
Lauren King¹, Esther Waugh¹, Ian Stanaitis², Alanna Weisman¹, Baiju Shah¹, Lorraine Lipscombe¹ and Gillian Hawker¹, ¹University of Toronto, Toronto, ON, Canada, ²Women's College Hospital, Toronto, ON, Canada
Background/Purpose: Knee osteoarthritis (OA) and type 2 diabetes commonly co-occur due to shared risk factors. Concomitant knee OA makes type 2 diabetes management, particularly engaging…
Abstract Number: 0462 • ACR Convergence 2022
Increasing Incidence of Large Artery Manifestations in Patients with Giant Cell Arteritis, a Population-based Cohort over 70 Years
Mohanad Elfishawi¹, Mahmut Kaymakci², Sara Achenbach³, Cynthia Crowson⁴, Tanaz Kermani⁵, Cornelia Weyand⁴, Matthew J. Koster¹ and Kenneth J. Warrington¹, ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Rochester, ³Mayo Clinic, Rochester, MN, Rochester, MN, ⁴Mayo Clinic, Eyota, MN, ⁵University of California Los Angeles, Los Angeles, CA
Background/Purpose: Screening for large artery manifestations has been adopted by clinicians managing patients with Giant Cell Arteritis (GCA). The contemporary effect of the increased use…
Abstract Number: 0713 • ACR Convergence 2022
The Epidemiology, Clinical Outcomes, and Healthcare Resource Utilization of IgG4-Related Disease Among Commercially Insured People in the United States
Zachary Wallace¹, Gandarvaka Miles², Ekaterina Smolkina³, Natalia Petruski-Ivleva², Duane Madziva², Claire Cook¹, Xiaoqing Fu¹, yuqing zhang⁴, John Stone⁵ and Hyon Choi⁶, ¹Massachusetts General Hospital, Boston, MA, ²Sanofi, Unknown, ³Sanofi, Amsterdam, Netherlands, ⁴Massachusetts General Hospital, Quincy, MA, ⁵Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ⁶MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA
Background/Purpose: IgG4-related disease (IgG4-RD) is an immune-mediated condition that causes fibroinflammatory lesions, often presenting as pancreatitis, cholangitis, sialoadenitis, and retroperitoneal fibrosis. The epidemiology of IgG4-RD,…

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