Abstracts tagged "Epidemiology"

Abstract Number: 1881 • ACR Convergence 2025
Silent Impact: Two Decades of Sjögren’s Syndrome Mortality in the United States
Aziz-ur-Rahman Khalid¹, Ghassan Makhoul², Hasan Munshi², Islam Rajab², MD Walid Akram Hussain², Reshma John², Elvira Assaf², Amer Al Badawy², Barbare Khatiashvili², Rouba Isshak², John Salama², Ibrahim Sabah² and Robert Lahita³, ¹St. Joseph's University Medical Center, wayne, ²St. Josephs University Medical Center, Paterson, ³St. Josephs University Medical Center, Wayne, NJ
Background/Purpose: Sjögren’s syndrome is a chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands with potential systemic involvement. Despite its known complications, population-level mortality…
Abstract Number: 1409 • ACR Convergence 2025
The impact of depression in axial spondyloarthritis: Epidemiological insights from the Ankylosing Spondylitis Registry of Ireland (ASRI)
Conall Mac Gearailt¹, Rebecca O'Farrell², Mohamed Eltahir³, Brian Hallahan³, Andrew Smyth⁴, Finbar O'Shea⁵ and Gillian Fitzgerald³, ¹Galway University Hospital, Galway, Galway, Ireland, ²Sligo University Hospital, Sligo, Ireland, ³Galway University Hospital, Galway, Ireland, ⁴University of Galway, Galway, Ireland, ⁵St James's Hospital and Trinity College Dublin, Dublin, Dublin, Ireland
Background/Purpose: The burden of comorbidities in Axial Spondyloarthritis (axSpA) is increasingly recognised and contributes to the concept of difficult-to-treat axSpA (D2T-axSpA). The need to assess…
Abstract Number: 1156 • ACR Convergence 2025
Incidence and Prevalence of Interstitial Pneumonia with Autoimmune Features in a Population-Based Cohort
elena Joerns¹, Sara Achenbach¹, Cynthia Crowson², eva carmona¹, Robert Vassallo³, John Joerns¹, Vanessa Kronzer³, John Davis³ and Elena myasoedova³, ¹Mayo Clinic, Rochester, ²Mayo Clinic, Stewartvillle, MN, ³Mayo Clinic, Rochester, MN
Background/Purpose: Interstitial pneumonia with autoimmune features (IPAF) is a type of interstitial lung disease (ILD) with features of autoimmunity, yet patients do not fulfill criteria…
Abstract Number: 1010 • ACR Convergence 2025
Confounding by Indication in Observational Studies Investigating Glucocorticoid-Associated Adverse Events in Patients with Rheumatoid Arthritis: A Systematic Literature Review
Andriko Palmowski¹, Anne Elisabeth Beenken², Anne Pankow², Judith Oldenkott², Henriette Käding², Edgar Wiebe³, Zhivana Boyadzhieva⁴, Eric L Matteson⁵, Ioanna Minopoulou⁶, Thorben Witte², David Simon⁷, Arnd Kleyer⁶ and FRANK BUTTGEREIT⁸, ¹Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ²Charité, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Berlin, Germany, ⁴Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Berlin, Germany, ⁵Mayo Clinic College of Medicine and Science, Rochester, MN, ⁶Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Germany, ⁷Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Germany, ⁸Charité University Medicine Berlin, Berlin, Berlin, Germany
Background/Purpose: Observational studies investigating glucocorticoids (GCs) and related adverse events (AEs) in patients with rheumatoid arthritis (RA) can suffer from bias by indication if confounders…
Abstract Number: 0541 • ACR Convergence 2025
Inflammatory Back Pain Is Not Associated With HLA-B27 Positivity or CRP Levels in a Nationally Representative U.S. Population
Mark Hwang¹, Seokhun Kim², Charles Green¹, Charles Dillon³, Shervin Assassi⁴, Michael Weisman⁵ and John Reveille⁶, ¹UTHealth Houston, Houston, TX, ²UTHealth Houston, Houston, ³NIH, Bethesda, MD, ⁴Division of Rheumatology, UTHealth Houston, Houston, Texas, USA, Houston, TX, ⁵Cedars-Sinai Medical Center, LOS ANGELES, CA, ⁶Department of Medicine, University of Texas Medical Center, Houston, TX
Background/Purpose: Inflammatory back pain (IBP) is a hallmark symptom of axial spondyloarthritis (axSpA) and is frequently used as a clinical entry point for further evaluation,…
Abstract Number: 0164 • ACR Convergence 2025
Online Patient Survey on the Impact of Extreme Weather Events on Autoimmune and Rheumatic Diseases
Iazsmin Ventura¹, Tamiko Katsumoto², Natasha Powell³, Elena Adams⁴ and Olivia Casey⁵, ¹Section of Rheumatology, University of Chicago, Chicago, ²Division of Immunology and Rheumatology, Stanford University, Millbrae, CA, ³University of Chicago Pritzker School of Medicine, Chicago, ⁴New Rochelle High School, New Rochelle, ⁵Autoimmune Association, Eastpointe
Background/Purpose: The impact of climate change on autoimmune and rheumatic diseases remains poorly understood. However, emerging evidence suggests extreme weather events, often related to climate…
Abstract Number: 2645 • ACR Convergence 2025
Age-specific Incidence of Systemic Lupus Erythematosus in the United States: A Meta-Analysis of Data from the Centers for Disease Control and Prevention Lupus Registries
Peter Izmirly¹, Elizabeth Ferucci², Aimee Hersh³, Mary Beth Son⁴, Cristina Drenkard⁵, S. Sam Lim⁶, Cynthia Crowson⁷, Ali Duarte-Garcia⁸, Jill Buyon⁹, Heather Gold⁹, Maria Dall'Era¹⁰, Patti Katz¹¹, Laura Plantinga¹², Jinoos Yazdany¹³, Jennifer Reihm¹⁴, Emily Somers¹⁵ and Hilary Parton¹⁶, ¹New York University Grossman School of Medicine, New York, NY, ²Alaska Native Tribal Health Consortium, Anchorage, AK, ³University of Utah, Salt Lake City, UT, ⁴Boston Children's Hospital, Boston, MA, ⁵Rollins School of Public Health, Emory University, Atlanta, Georgia, USA, Acworth, GA, ⁶Emory University School of Medicine, Atlanta, GA, ⁷Mayo Clinic, Stewartvillle, MN, ⁸Mayo Clinic, Rochester, MN, ⁹NYU Grossman School of Medicine, New York, NY, ¹⁰Division of Rheumatology, University of California, San Francisco, CA, ¹¹UCSF, San Rafael, CA, ¹²University of California, San Francisco, San Francisco, CA, ¹³UCSF, San Francisco, CA, ¹⁴University of California, San Francisco, San Francisco, ¹⁵University of Michigan, Ann Arbor, MI, ¹⁶New York City Department of Health and Mental Hygiene, New York
Background/Purpose: Current estimates for age of SLE onset are limited, particularly for males and racial/ethnic groups in the United States. Leveraging five Centers for Disease…
Abstract Number: 2113 • ACR Convergence 2025
Mortality rate in patients with hip fracture: is it recommendable to establish fracture units?
Esther Monleon Acosta¹, Alicia Pérez González², José Andrés Rodríguez Fernández², Pedro José Manuel Hernández², María del Rosario Oliva Ruiz², José María Andreu Ubero², Paloma Valentina Castillo Dayer², Gloria Albaladejo Paredes³, Carlos Fernández Díaz⁴, Angela Egea Fuentes², Montserrat Fernández Salamanca² and Vicente Cogolludo Campillo⁵, ¹Hospital Santa Lucia, Cartagena, Spain, ²Hospital General Universitario Santa Lucia, Cartagena, Spain, ³Hospital General Universitario Santa Lucía, CARTAGENA, Spain, ⁴H.U. Santa Lucia, Murcia, Spain, ⁵Hospital General Universitario Santa Lucia, Santa Lucia, Cartage, Spain
Background/Purpose: Hip fracture is the second most common osteoporotic fracture and the one with the highest socio-economic cost. It is associated with high morbidity and…
Abstract Number: 1906 • ACR Convergence 2025
The incidence and mortality of connective tissue diseases in England: a population-level cohort study from 2012 to 2023
Samir Patel¹, Mark Russell¹, Katie Bechman¹, Maryam Adas¹, Zijing Yang¹, Edward Alveyn¹, Chris Wincup², Alexandru Dregan¹, Kate Bramham¹, Sam Norton¹, James Galloway¹ and Patrick Gordon¹, ¹King's College London, London, United Kingdom, ²King's College Hospital, London, United Kingdom
Background/Purpose: The reported incidence and mortality of connective tissue diseases (CTDs) in England has been inconsistent in the literature. Our objective was to describe current…
Abstract Number: 1880 • ACR Convergence 2025
Rheumatoid Arthritis Mortality in the U.S. (1999–2020): A Decline in Rates, But Not in Disparities
Aziz-ur-Rahman Khalid¹, Ghassan Makhoul², Hasan Munshi², Islam Rajab², Emmanuel Olumuyide³, MD Walid Akram Hussain², Aqsa Sorathia², Elvira Assaf², Amer Al Badawy², John Salama² and Robert Lahita⁴, ¹St. Joseph's University Medical Center, wayne, ²St. Josephs University Medical Center, Paterson, ³Advocate Illinois Masonic Medical Center, Chicago, ⁴St. Josephs University Medical Center, Wayne, NJ
Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease associated with increased morbidity and mortality. While treatments have evolved, national trends and sociodemographic disparities in…
Abstract Number: 1394 • ACR Convergence 2025
Burden of Comorbidities Across EULAR Sjögren’s Syndrome Disease Activity Index (ESSDAI) Domains: Treatment Prevalence Among Commercially Insured Sjögren’s Patients in the United States
Minoti Ganguli, Annie Kilby, Ahva Shahabi and Tsu-Chieh Jay Lin, Amgen Inc., Thousand Oaks, CA
Background/Purpose: Sjögren’s disease (SjD) is a systemic disorder characterized by exocrine gland inflammation, leading to dry eyes/mouth, and multiple organ systems involvement1. The European League…
Abstract Number: 1099 • ACR Convergence 2025
Safety and Effectiveness of Hydroxychloroquine in the Treatment of Rheumatic Immune-Related Adverse Events
Grace Haeun Lee¹, Gregory Challener², Janeth Yinh³, Jeffrey Sparks⁴, Kerry L. Reynolds⁵, Donald P. Lawrence⁵, Meghan J. Mooradian⁵, Ryan J. Sullivan⁵, Hyon K. Choi⁶ and Minna Kohler⁷, ¹Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, ²Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, ³Massachusetts General Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston, MA, ⁵Massachusetts General Hospital, Boston, ⁶MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, ⁷Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Hydroxychloroquine (HCQ) has been recommended [1-3] as a steroid-sparing agent for immune checkpoint inhibitor-inflammatory arthritis (ICI-IA), preferred due to its low immunosuppressive effect. However,…
Abstract Number: 1009 • ACR Convergence 2025
Pregnancy Outcomes and Comorbidities Among Individuals with Systemic Lupus Erythematosus: A Nationwide Study Using Publicly Funded Health Insurance Claims Data
Amadeia Rector¹, Sadaf Sediqi², Alyssa Howren² and Julia F Simard³, ¹Stanford University, San Francisco, CA, ²Stanford University, Palo Alto, CA, ³Stanford Medicine, Stanford, CA
Background/Purpose: Individuals with SLE are at increased risk for pregnancy complications such as preeclampsia and preterm delivery. As SLE is commonly diagnosed and active during…
Abstract Number: 0522 • ACR Convergence 2025
The Incidence Rate and Risk Factors of Arrhythmias in Patients with Psoriatic Arthritis
Abdulrahman Y Almansouri¹, Jiayi Li², Ali Alhadri³, Keith Colaco⁴, Paula Harvey⁵, Shadi Ahktari⁶, Vinod Chandran⁷, Dafna D. Gladman⁸, Richard Cook² and Lihi Eder⁷, ¹King Faisal Specialist Hospital and Research Centre, University of Toronto and Women's College Hospital, Toronto, Canada, ²University of Waterloo, Waterloo, Canada, ³King Fahad Hospital, University of Toronto and Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, Canada, ⁴University of Toronto, Toronto, Canada, ⁵University of Toronto Department of Medicine and Women's College Hospital, Toronto, ON, Canada, ⁶University of Toronto Department of Medicine and Women's College Hospital, Toronto, Canada, ⁷University of Toronto, Toronto, ON, Canada, ⁸Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada
Background/Purpose: Patients with psoriatic arthritis (PsA) are at increased risk of developing cardiovascular diseases, including arrhythmias. Given that traditional cardiovascular disease risk factors are prevalent…
Abstract Number: 0161 • ACR Convergence 2025
Risk Factors and Clinical Predictors of Lung Cancer in Systemic Sclerosis: A Matched Case-Control Study from a Michigan Cohort
Madiha Naqsh Siddiqui¹, Yen Chen¹, Rosemary Gedert², Suiyuan Huang², Dinesh Khanna² and John Varga², ¹University of Michigan, Ann Arbor, ²University of Michigan, Ann Arbor, MI
Background/Purpose: Malignancies are one of the leading causes of non-systemic sclerosis-related mortality in patients with systemic sclerosis (SSc)1, with lung cancer being the most common…

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