ACR Meeting Abstracts

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Abstracts tagged "Epidemiology"

  • Abstract Number: 1454 • ACR Convergence 2022

    A High Genetic Risk of SLE Is Associated with an Increased Risk of Myocardial Infarction; A Combined Observational and Mendelian Randomization Study

    Sarah Reid1, Johanna K Sandling1, Pascal Pucholt1, Ahmed Sayadi1, Christopher Sjöwall2, Karoline Lerang3, Andreas Jönsen4, Anders A Bengtsson4, Øyvind Molberg3, Anna Rudin5, Solbritt Rantapää-Dahlqvist6, Lars Ronnblom7 and Dag Leonard1, 1Rheumatology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, 2Department of Biomedical and Clinical Sciences, Division of Inflammation and Infection, Linköping University, Linköping, Sweden, 3Department of Rheumatology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, 4Department of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Lund and Skåne University Hospital, Lund, Sweden, 5Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy of University of Gothenburg, Gothenburg, Sweden, 6Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, 7Uppsala University, Uppsala, Sweden

    Background/Purpose: The reasons for the high cardiovascular morbidity in patients with SLE are not fully understood. Here, we combine a mendelian randomization (MR) approach and…
  • Abstract Number: 1668 • ACR Convergence 2022

    Rheumatic Toxicities of Immune Checkpoint Inhibitors Predict Favourable Tumour Responses in Patients with Advanced Melanoma

    Alana Bruce1, Alexander M Menzies2, Georgina V Long2, Brian Fernandes3 and Fredrick Joshua4, 1Macquarie University, Balaclava, Victoria, Australia, 2Melanoma Institute Australia, The University of Sydney, Royal North Shore and Mater Hospitals, Sydney, Australia, 3Royal Prince Alfred Hospital, Sydney, Australia, 4Macquarie University, Integrated Specialist Medical Care, Sydney, Australia

    Background/Purpose: To estimate the frequency of rheumatic toxicities of immune checkpoint inhibitors (ICI) presenting as de novo or exacerbations of pre-existing rheumatic disease in patients…
  • Abstract Number: 1857 • ACR Convergence 2022

    Increasing Proportion of MDA-5 Associated Conditions in a Tertiary Myositis Centre Following Onset of the Covid-19 Pandemic

    Jennifer Hannah1, Saadia Sasha Ali1, Sloni Arora1, John Cazabon1, James Galloway1 and Patrick Gordon2, 1King's College London, London, United Kingdom, 2King’s College Hospital NHS Foundation Trust, London, United Kingdom

    Background/Purpose: Anti-MDA5 dermatomyositis is a clinical subtype of DM that is strongly associated with a rapidly progressive phenotype of interstitial lung disease resulting in a…
  • Abstract Number: 2250 • ACR Convergence 2022

    Genetic and Environmental Risk Factors in Rheumatoid Arthritis-Associated Interstitial Lung Disease

    Austin Wheeler1, Yangyuna Yang1, Joshua Baker2, Jill Poole1, Dana Ascherman3, Gail Kerr4, Andreas Reimold5, Gary Kunkel6, Grant Cannon7, Katherine Wysham8, Namrata Singh9, Deana Lazaro10, Paul Monach11, S. Louis Bridges, Jr.12, Ted Mikuls13 and Bryant England1, 1University of Nebraska Medical Center, Omaha, NE, 2University of Pennsylvania, Philadelphia, PA, 3University of Pittsburgh, Pittsburgh, PA, 4Washington DC VAMC/Georgetown and Howard Universities, Washington, DC, 5University of Texas Southwestern Medical Center, Dallas, TX, 6University of Utah, Salt Lake City, UT, 7Retired, Salt Lake City, UT, 8VA Puget Sound/University of Washington, Seattle, WA, 9University of Washington, Bellevue, WA, 10VA New York Harbor Healthcare system, Short Hills, NJ, 11VA Boston Healthcare System, Boston, MA, 12Hospital for Special Surgery, New York, NY, 13Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: RA-associated interstitial lung disease (RA-ILD) is an extra-articular manifestation of RA causing substantial morbidity and mortality. Genetic risk variants, such as the MUC5B rs35705950…
  • Abstract Number: 0458 • ACR Convergence 2022

    Predictive Models for Thromboembolic Events in Giant Cell Arteritis: A US Veterans Health Administration Population-Based Study

    Despina Michailidou1, Tianyu Zhang2, Andreas Diamantopoulos3, Pavlos Stamatis4 and Bernard Ng5, 1Division of Rheumatology, University of Washington, Seattle, WA, 2Department of Biostatistics, University of Washington, Seattle, WA, 3Akershus University Hospital, Lørenskog, Norway, 4Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden, Larissa, Larisa, Greece, 5Rheumatology Section, VA Puget Sound Healthcare System, Seattle, WA

    Background/Purpose: Giant cell arteritis (GCA) is an independent risk factor for thromboembolic events. The purpose of our study was to identify prognostic factors for thromboembolic…
  • Abstract Number: 0709 • ACR Convergence 2022

    Population Based Prevalence and Incidence of Mixed Connective Tissue Disease from the Manhattan Lupus Surveillance Program

    Ghadeer Hasan1, Elizabeth Ferucci2, Jill Buyon3, H Michael Belmont4, Sara Sahl5, Jane Salmon6, Anca Askanase7, Joan Bathon7, Laura Geraldino-Pardilla8, Yousaf Ali9, Ellen M. Ginzler10, Chaim Putterman11, Caroline Gordon12, Hilary Parton13 and Peter Izmirly3, 1New York University, New York, NY, 2Alaska Native Tribal Health Consortium, Anchorage, AK, 3NYU Grossman School of Medicine, New York, NY, 4NYU School of Medicine, New York, NY, 5Harbor-University of California Medical Center, Los Angeles, CA, 6Hospital for Special Surgery, New York, NY, 7Columbia University Medical Center, New York, NY, 8Columbia University, New York, NY, 9Icahn School of Medicine at Mount Sinai, New York, NY, 10SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 11Albert Einstein College of Medicine, Bronx, NY, 12Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, 13New York City Department of Health and Mental Hygiene, New York, NY

    Background/Purpose: The epidemiology of mixed connective tissue disease (MCTD) is not well described. Leveraging data from the Manhattan Lupus Surveillance Program (MLSP), a racially/ethnically diverse…
  • Abstract Number: 0898 • ACR Convergence 2022

    Risk of Aortic Stenosis and Undergoing Aortic Valve Replacement in Rheumatoid Arthritis: An Underrecognized Cardiovascular Complication

    Tate Johnson1, Yangyuna Yang2, Chetaj Mahabir2, Andrew Goldsweig2, Punyasha Roul3, Joshua Baker4, Brian Sauer5, Grant Cannon6, Ted Mikuls7 and Bryant England2, 1University of Nebraska Medical Center, Elkhorn, NE, 2University of Nebraska Medical Center, Omaha, NE, 3UNMC, Omaha, NE, 4University of Pennsylvania, Philadelphia, PA, 5Salt Lake City VA/University of Utah, Salt Lake City, UT, 6Retired, Salt Lake City, UT, 7Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Valvular carditis is reported as a rare extra-articular manifestation of rheumatoid arthritis (RA). In animal models with coexistent inflammatory arthritis, pro-inflammatory infiltrates of T…
  • Abstract Number: 1206 • ACR Convergence 2022

    Association Between Different Alcoholic Beverages and Serum Urate Level: A Cross-Sectional Study Using Large Medical Checkup Data

    Sho Fukui1, Masato Okada2, Mahbubur Rahman3, Takehiro Nakai2, Hiromichi Tamaki2, Hiroki Matsui4, Atsushi Shiraishi5, Mitsumasa Kishimoto6, Hiroshi Hasegawa7, Takeaki Matsuda7 and Kazuki Yoshida8, 1Kyorin University Hospital, Tokyo, Japan, 2St. Luke's International Hospital, Tokyo, Japan, 3Graduate School of Public Health, St. Luke’s International University, Tokyo, Japan, 4Clinical Research Support Office, Kameda Medical Center, Kamogawa, Japan, 5Emergency and Trauma Center, Kameda Medical Center, Kamogawa, Japan, 6Kyorin University School of Medicine, Yokohama, Japan, 7Kyorin University, Tokyo, Japan, 8Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Alcohol consumption is associated with increased serum urate levels. However, data regarding the differences in the extent of the association between various types of…
  • Abstract Number: 1471 • ACR Convergence 2022

    Trends and Predictors of Hospitalizations Due to Acute Myocardial Infarction in Systemic Lupus Erythematosus Patients

    Izza Bazigh1, Uzair Khan2, Achint Patel3, Aaparna Singh3, Neha Ghalib3, Ghazi Farman4, Salman Muddassir3, Farrukh Zaidi5, Sami Mughni3 and Adam Grunbaum6, 1HCA Florida Oak Hill Hospital, Spring Hill, FL, 2HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Odessa, FL, 3HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Spring Hill, FL, 4Rehman Medical College, Spring Hill, FL, 5HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Port Richey, FL, 6Gulf Coast Rheumatology, Trinity, FL

    Background/Purpose: Cardiovascular events occur more frequently and with earlier onset in patients with Systemic Lupus Erythematosus (SLE) compared with healthy individuals. Several studies have concluded…
  • Abstract Number: 1750 • ACR Convergence 2022

    Association Between Appendicitis and the Risk of Systemic Lupus Erythematosus: A Population-based, Case-control Study

    Yun-Wen Chen, Taichung Veterans General Hospital, Taichung, Taiwan

    Background/Purpose: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by diverse clinical manifestations. The risk factors of SLE included genetic factors and environmental…
  • Abstract Number: 1912 • ACR Convergence 2022

    Associations of Nociceptive Dysfunction with Physical Activity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

    Deepak Kumar1, Na Wang2, Kaveh Torabian1, Kosaku Aoyagi3, Joshua Stefanik4, Laura Frey-Law5, Lisa Carlesso6, Jeffrey Hausdorff7, Eran Gazit7, Neil Segal8, Cora E. Lewis9, Michael Nevitt10 and Tuhina Neogi2, 1Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Boston University, Quincy, MA, 4Northeastern University, Boston, MA, 5University of Iowa, Iowa City, IA, 6McMaster University, Hamilton, ON, Canada, 7Tel Aviv Suarasky Medical Center, Tel Aviv, Israel, 8University of Kansas, Kansas City, KS, 9University of Alabama at Birmingham, Birmingham, AL, 10University of California San Francisco, Orinda, CA

    Background/Purpose: Individuals with chronic pain due to knee osteoarthritis (OA) are insufficiently physically active and increasing physical activity is the first line recommendation for management…
  • Abstract Number: 2275 • ACR Convergence 2022

    Three Dose SARS-CoV-2 Vaccination Is Associated with Reduced Risk of Breakthrough COVID-19 During Omicron Wave in Patients with Autoimmune Diseases

    Caoilfhionn Connolly1, Rachel Wallwork1, Teresa Po-Yu Chiang1, Mayan Teles1, Jennifer Alejo1, Allan Massie2, Ami Shah3, Jemima Albayda1, Lisa Christopher-Stine1, Dorry Segev2, William Werbel1 and Julie Paik1, 1Johns Hopkins University, Baltimore, MD, 2NYU Langone Health, New York, NY, 3Johns Hopkins Rheumatology, Baltimore, MD

    Background/Purpose: While SARS-CoV-2 vaccination mitigates the risk of severe COVID-19, vaccinated patients with autoimmune diseases are more susceptible to infection despite vaccination ("breakthrough" COVID-19) and…
  • Abstract Number: 0459 • ACR Convergence 2022

    The Use of Intravenous Methylprednisolone in Patients with Giant Cell Arteritis: A Population-Based Study

    Hampus Henningson1, Björn Hammar2, Carl Turesson3 and Aladdin Mohammad1, 1Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden, 2Ophthalmology, Department of Clinical Sciences, Lund University, Lund, Sweden, 3Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden

    Background/Purpose: Giant cell arteritis (GCA) is the most common vasculitis in the age-group 50 years and older. Cranial involvement is common and can lead to…
  • Abstract Number: 0711 • ACR Convergence 2022

    Improvement in Excess Mortality in Patients with Rheumatoid Arthritis over the Last Two Decades: A Danish Population-based Matched Cohort Study

    Bolette Soussi1, Kirsten Duch1, René Cordtz1, Christian Bork2, Salome Kristensen1, Erik Schmidt2, Jesper Lindhardsen3 and Lene Dreyer1, 1Center of Rheumatic Research Aalborg, Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, 2Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark, 3Lupus and Vasculitis Clinic, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark

    Background/Purpose: Results from previous studies investigating mortality trends in patients with rheumatoid arthritis (RA) have been inconsistent, most likely due to varying cohort sizes and…
  • Abstract Number: 0905 • ACR Convergence 2022

    Predicting Disease Activity in Rheumatoid Arthritis Patients Using Machine Learning: Data from the ACR’s RISE Registry

    Eren-Ajani Tshimanga1, Milena Gianfrancesco2, Stefanos Giampanis3, Jing Li2, Emma Kersey4, Jinoos Yazdany5, Beau Norgeot6, Gabriela Schmajuk7 and Zara Izadi4, 1University of California, Berkeley, Berkeley, CA, 2University of California, San Francisco, San Francisco, CA, 3Anthem, San Francisco, 4University of California San Francisco, San Francisco, CA, 5UCSF, San Francisco, CA, 6Anthem, Oakland, CA, 7UCSF / SFVA, San Francisco, CA

    Background/Purpose: Predicting the trajectory of disease in individuals with RA is difficult, with numerous factors influencing whether a patient may experience higher or lower disease…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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