Abstracts tagged "Environmental factors"

Abstract Number: 2141 • 2012 ACR/ARHP Annual Meeting
Effects of Cigarette Smoking On EARLY Arthritis (CONAART)
Maria Haye Salinas¹, Ana C. Alvarez¹, Rafael Chaparro del Moral², Mariana Benegas², Christian A. Waimann³, Rodolfo Perez Alamino⁴, Rodrigo Garcia Salinas⁵, Ana Lucía Barbaglia⁶, Veronica Bellomio⁷, Josefina Marcos⁸, Adrian Salas⁹, Cristian Quiroz¹⁰, Federico Ceccato¹¹, Sergio Paira¹¹, Dora Lia Vazquez¹², Gabriela Salvatierra¹³, M. Crespo¹⁴, Edson Javier Velozo¹⁵, Oscar L. Rillo¹⁶, Enrique Soriano¹⁷, Antonio Catalan Pellet⁵, Alberto Berman Sr.¹⁸, Juan Carlos Marcos¹⁹, Gustavo Citera²⁰ and Francisco Caeiro²¹, ¹Rheumatology, Hospital Privado, Córdoba, Argentina, ²Rheumatology, Hospital Tornu, Buenos Aires, Argentina, ³Rheumatology section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Rheumatology, Louisiana State University, New Orleans, LA, ⁵Rheumatology, Hospital Rivadavia, Buenos Aires, Argentina, ⁶Rheumatology, Hospital Padilla, Tucuman, Argentina, ⁷Centro Medico Privado de Reumatologia, Tucuman, Argentina, ⁸Rheumatology Unit, HIGA San Martín La Plata, La Plata, Argentina, ⁹Hospital San Martin, La Plata, Argentina, ¹⁰Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹¹Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, ¹²Rheumatology, Centro Integral de Reumatologia, Santiago del Estero, Argentina, ¹³Rheumatology, Centro de enfermedades Reumaticas, Santiago Del Estero, Argentina, ¹⁴Rheumatology, Hospital Señor del Milagro, Salta, Argentina, ¹⁵Rheumatology, Sanatorio Adventista del Plata, Entre Rios, Argentina, ¹⁶Rheumatology, Hospital General de Agudos "Dr. E. Tornú", Buenos Aires, Argentina, ¹⁷Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ¹⁸Internal Medicine, Hospital Padilla, Tucuman, Argentina, ¹⁹Rheumatology, Hospital San Martin, La Plata, Argentina, ²⁰Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ²¹Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina
Background/Purpose: According to recent reports the cigarette smoking persons have 2-4 times greater risk of developing rheumatoid arthritis (RA). The cigarette smoking is associated with…
Abstract Number: 1692 • 2012 ACR/ARHP Annual Meeting
Lung Microbiome Differs in Subjects with Rheumatoid Arthritis-Related Autoimmunity without Inflammatory Arthritis Compared to Healthy Seronegative Controls
M. Kristen Demoruelle¹, Jill M. Norris², V. Michael Holers³, Kevin D. Deane¹ and J. Kirk Harris⁴, ¹Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ²Epidemiology, Colorado School of Public Health, Aurora, CO, ³Rheumatology Division, University of Colorado School of Medicine, Aurora, CO, ⁴University of Colorado Anschutz Medical Campus, Aurora, CO
Background/Purpose: Emerging data suggest that microorganisms and mucosal inflammation may play a role in the etiology of rheumatoid arthritis (RA). Furthermore, our published findings…
Abstract Number: 1210 • 2012 ACR/ARHP Annual Meeting
Effect of HLA-DRB1*0901 Suggest Distinctive Mechanisms of Rheumatoid Arthritis Susceptibility
So-Young Bang¹, Hye-Soon Lee², Kyung Wha Lee³ and Sang-Cheol Bae⁴, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ³Hallym Institute for Genome Application,Hallym University Sacred Heart Hospital, Anyang, South Korea, ⁴Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Although HLA-DRB1 shared epitope (SE) alleles and DRB1*0901 have repeatedly been shown to be associated with RA susceptibility, the effect of each allele on…
Abstract Number: 976 • 2012 ACR/ARHP Annual Meeting
Effect of Interactions Between Validated Rheumatoid Arthritis Genetic Factors and Environmental Factors On Rheumatoid Arthritis Risk
Chia-Yen Chen¹, Linda T. Hiraki², Susan Malspeis³, Jing Cui⁴, Bing Lu⁴, Robert M. Plenge⁵, Karen H. Costenbader⁴ and Elizabeth W. Karlson⁶, ¹Department of Epidemiology, Harvard School of Public Health, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, ³Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁴Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy and Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ⁶Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Studies have shown associations between environmental factors and rheumatoid arthritis (RA) risk. Also, genome-wide association studies (GWAS) have identified genetic markers associated with RA…

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