ACR Meeting Abstracts

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Abstracts tagged "Elderly"

  • Abstract Number: 2324 • 2018 ACR/ARHP Annual Meeting

    Predictors of Refracture in Patients with Hip Fragility Fracture

    Sara Ganhão1,2, Miguel Guerra3, Francisca Aguiar1,2, Georgina Terroso1, Romana Vieira3, Diana Gonçalves4, Teresa Martins-Rocha2,5, Raquel Ferreira1,2, Ana Águeda2,6, Tiago Meirinhos7, Eva Mariz1,2, Raquel Lucas8, Miguel Bernardes1,2, Carlos Vaz1,2 and Lúcia Costa1, 1Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, 2Faculty of Medicine, Oporto University, Oporto, Portugal, 3Rheumatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal, 4Rheumatology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, 5Rheumatology Department, Centro Hospitalar de São João, Porto, Portugal, Oporto, Portugal, 6Rheumatology, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, 7Serviço de Reumatologia, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, Aveiro, Portugal, 8Public Health, Centro Hospitalar de São João, Oporto, Portugal

    Background/Purpose: Hip fractures are associated with substantially elevated morbidity and mortality and thus represent a serious public health problem. The purpose of this study is…
  • Abstract Number: 226 • 2018 ACR/ARHP Annual Meeting

    Representation of Elderly People and Women in Rheumatoid Arthritis and Osteoarthritis Trials: A Systematic Review and Meta-Analysis Comparing Clinical Trials with Population-Based Studies

    Andriko Palmowski1, Thomas Buttgereit1,2, Yannick Palmowski3, Sabrina Mai Nielsen4,5, Maarten Boers6, Robin Christensen4,5 and Frank Buttgereit1, 1Department of Rheumatology and Clinical Immunology, Charité – University Medicine Berlin, Berlin, Germany, 2Department of Dermatology, Venerology and Allergology, Charité – University Medicine Berlin, Berlin, Germany, 3Center for Musculoskeletal Surgery, Charité – University Medicine Berlin, Berlin, Germany, 4Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, 5Department of Rheumatology, Odense University Hospital, Odense, Denmark, 6Department of Epidemiology and Biostatistics, and Amsterdam Rheumatology and Immunology Center, VU University Medical Center, Amsterdam, Netherlands

    Background/Purpose: Elderly people (as commonly defined by an age of ≥65 years) and women have been reported to be underrepresented in clinical trials of various…
  • Abstract Number: 387 • 2018 ACR/ARHP Annual Meeting

    Increased Risk of Malignancy in Elderly Patients with Inflammatory Myositis

    Hyoungyoung Kim1, Yoon-Kyoung Sung2, Seongmi Choi3, Jinwook Kim4, Sun-Young Jung5, Eun Jin Jang6, Dae-Hyun Yoo7 and Soo-Kyung Cho1, 1Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), 2Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South), 3Statistics, Kyungpook National University, Daegu, Korea, Republic of (South), 4Department of Statistics, Kyungpook National University, Daegu, Korea, Republic of (South), 5College of Pharmacy, Chung-Ang University, Seoul, Korea, Republic of (South), 6Information Statistics, Andong National University, Andong-si, Korea, Republic of (South), 7Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of (South)

    Background/Purpose: The association between inflammatory myositis and malignancy is well established, however, the risk of malignancy in aged patients is known to be similar with…
  • Abstract Number: 303 • 2017 ACR/ARHP Annual Meeting

    Outcomes after Hip Fracture in the Elderly: Does Social Isolation Matter?

    Lisa A. Mandl1, Omar Halawa2, Jackie Szymonifka3, Kirsten Grueter4 and Joseph Lane5, 1Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 5Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
  • Abstract Number: 540 • 2017 ACR/ARHP Annual Meeting

    Being Elderly Is Not a Predictive Factor of Discontinuation of Abatacept Due to Adverse Events in Rheumatoid Arthritis Patients with Concomitant Methotrexate: A Retrospective Observational Study Based on Data from a Japanese Multicenter Registry Study

    Nobunori Takahashi, Toshihisa Kojima, Shuji Asai, Tatsuo Watanabe, Takuya Matsumoto, Nobuyuki Asai, Yasumori Sobue and Naoki Ishiguro, Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Background/Purpose: Abatacept is a new class of biologic agent for the treatment of rheumatoid arthritis (RA) that inhibits T cell activation by binding to CD80/86.…
  • Abstract Number: 1770 • 2017 ACR/ARHP Annual Meeting

    ANCA-Associated Vasculitis (AAV) in Younger Vs Older Patients:  Comparison of Clinical, Serologic and Outcome Differences and Their Implications for Management

    Priya Chokshi1, Olufemi Aina2, Naveed Masani2, Melissa Fazzari3, Elise Belilos1, Kristina Belostocki1, Gary Rosenblum1, Tobin Abraham4, Daniil Shimonov4, Zinal Patel4 and Steven E. Carsons1, 1Rheumatology, NYU Winthrop Hospital, Mineola, NY, 2Nephrology, NYU Winthrop Hospital, Mineola, NY, 3Biostatistics, NYU Winthrop Hospital, Mineola, NY, 4Medicine, NYU Winthrop Hospital, Mineola, NY

    Background/Purpose: ANCA-associated vasculitis (AAV) is a cause of multi-organ disease in all ages, but peaks at ages 65-74. Limited data is available on the characteristics…
  • Abstract Number: 1852 • 2017 ACR/ARHP Annual Meeting

    Validating Patient Reported Outcomes in Older Veterans with Chronic Back Pain

    Rabih Nayfe1, Matthieu Chansard2, Thiru Annaswamy3, Katharine McCallister2, Liana Fraenkel4, Eric Mortensen5 and Una E. Makris6, 1Department of Medicine, UT Southwestern Medical Center, Dallas, TX, 2Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, 3Physical Medicine & Rehabilitation,, VA North Texas Health Care System, Dallas, TX, 4Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, 5Department of Medicine, University of Connecticut, Farmington, CT, 6Department of Medicine, VA North Texas Health Care System, Dallas, TX

    Background/Purpose: Chronic back pain is the second most common reason for a physician’s visit and results in significant physical and psychosocial consequences in older adults.…
  • Abstract Number: 1961 • 2017 ACR/ARHP Annual Meeting

    Risk Factors for Low Muscle MASS in Community-Dwelling Older Women: A Population-Based Prospective Cohort Study in Brazil. the São Paulo Ageing & Health Study

    Ketty Machado1, Diogo S Domiciano2, Luana G Machado3, Jaqueline B Lopes4, Camille P Figueiredo5, Valéria F. Caparbo3, Liliam Takayama3, Paulo Menezes6 and Rosa M R Pereira2, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, 3Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, 5Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, 6Preventive medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Sarcopenia is a syndrome characterized by progressive loss of skeletal muscle mass, which results in decreased muscle strength and impairment of functional capacity. Moreover,…
  • Abstract Number: 2409 • 2017 ACR/ARHP Annual Meeting

    Older Age and Male Gender Are Independent Predictors of Quantiferon Positivity Among Adult Rheumatic Patients in a Tertiary Care Center from a BCG Vaccinated Country: Hur-BIO Single Center Real Life Results

    Emrah Seyhoglu1, Oguz Abdullah Uyaroglu1, Abdulsamet Erden2, Levent Kilic2, Berkan Armagan2, Alper Sari2, Omer Karadag2, Sule Apras Bilgen2, Ali Akdogan2, Ihsan Ertenli2, Umut Kalyoncu2 and Sedat Kiraz2, 1Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey

    Background/Purpose: TNF-α inhibitors increase the risk of emergence of active tuberculosis (TB). Screening rheumatic patients for latent TB is a necessity before initiation of biological…
  • Abstract Number: 2494 • 2017 ACR/ARHP Annual Meeting

    Analysis of the Efficacy, Safety and Continuation Rate of Abatacept in Elderly Patients with Rheumatoid Arthritis

    Mayumi Matsuda1, Yu Funakubo Asanuma2, Noritsune Kouzu3 and Toshihide Mimura2, 1Department of Rheumatology and Applied Immunology, Saitama Medical University, Moroyama-machi, Japan, 2Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, 3Saitama Medical University, Moroyama, Japan

    Background/Purpose: The elderly rheumatoid arthritis (RA) patients have declined physical performances and various complications. The efficacy of the biological DMARDs may decrease in elderly RA…
  • Abstract Number: 201 • 2016 ACR/ARHP Annual Meeting

    Allopurinol Reduces the Risk of Myocardial Infarction (MI) in the Elderly: A Study of Medicare Claims

    Jasvinder A. Singh1 and Shaohua Yu2, 1Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: To assess whether allopurinol use reduces the risk of myocardial infarction (MI) in the elderly. Methods: We used the 2006-2012 5% random sample of…
  • Abstract Number: 1605 • 2016 ACR/ARHP Annual Meeting

    Pooled Safety and Efficacy of Sarilumab in Rheumatoid Arthritis Patients 65 Years of Age and Older

    Roy Fleischmann1, Mark C. Genovese2, Janet van Adelsberg3, Erin Mangan4, Melitza Iglesias-Rodriguez5, Deborah Dukovic6 and TWJ Huizinga7, 1Medicine, University of Texas Southwestern Medical Center, Dallas, TX, 2Stanford University Medical Center, Palo Alto, CA, 3Clinical Science, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 4Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 5Sanofi Genzyme, Cambridge, MA, 6Sanofi Genzyme, Bridgewater, NJ, 7Leiden University Medical Centre, Leiden, Netherlands

    Background/Purpose: Sarilumab is a human mAb blocking the IL-6Rα. Sarilumab (150 or 200 mg every 2 weeks [q2w] subcutaneously) + MTX demonstrated efficacy vs placebo…
  • Abstract Number: 1613 • 2016 ACR/ARHP Annual Meeting

    Safe and Effective Tocilizumab Therapy in Elderly Patients with Rheumatoid Arthritis

    Christof Specker1, Jörg Kaufmann2, Herbert Kellner3, Peter Kaestner4, Christoph Volberg5, Verena Braunewell6, Martin Aringer7, Maren Sieburg8, Lothar Meier9, Michael Hofmann10, Jan-Paul Flacke11, Hans-Peter Tony12 and Gerhard Fliedner13, 1Rheumatology & Clinical Immunology, University Hospital Essen, Essen, Germany, 2Ambulant Centres for Rheumatology, Ludwigsfelde, Germany, 3Specialist Practice for Rheumatology and Gastroenterology, Munich, Germany, 4Outpatient department of Rheumatology, MVZ Ambulantes Rheumazentrum, Erfurt, Germany, 5Rheumazentrum Neuss, Neuss, Germany, 6Schwerpunktpraxis Rheumatologie, Moenchengladbach, Germany, 7Rheumatology, Medicine III, University Clinical Center Technical University of Dresden, Dresden, Germany, 8Rheumatologische Gemeinschaftspraxis, Magdeburg, Germany, 9Gemeinschaftspraxis für Innere Medizin - Rheumatologie, Hofheim am Taunus, Germany, 10Rheumatology, Chugai Pharma Europe Ltd., Frankfurt, Germany, 11Rheumatology, Roche Pharma AG, Grenzach-Wyhlen, Germany, 12Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Würzburg, Germany, 13Internal Med/Rheumatology, Rheumatological Practice, Osnabrueck, Germany

    Background/Purpose: The non-interventional study ICHIBAN was set up in 2010 to evaluate the effectiveness and safety of intravenously administered Tocilizumab (TCZ IV) in patients (pts)…
  • Abstract Number: 2672 • 2016 ACR/ARHP Annual Meeting

    Elderly Patients Risk a False Positive Diagnosis of Primary Sjogren’s Syndrome If a Positive Labial Gland Biopsy Is Solely Based on Focus Score

    Erlin A. Haacke1,2, Jolien F. van Nimwegen1, Martha S. van Ginkel1, Suzanne Arends1, Fred K.L. Spijkervet3, Gwenny M. Verstappen1, Nicole Sillevis Smitt-Kamminga4, Arjan Vissink5, Frans G.M. Kroese1, Bert van der Vegt6 and Hendrika Bootsma7, 1Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 4Opthalmology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 5Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 6Pathology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 7Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands

    Background/Purpose:  Primary Sjögren’s syndrome (pSS) is a systemic auto-immune disease affecting the exocrine glands leading to sicca complaints. For the diagnosis of pSS, a positive…
  • Abstract Number: 3070 • 2016 ACR/ARHP Annual Meeting

    Effect of Sarcopenia, Subcutaneous Adipose Tissue and Abdominal Visceral Fat on Mortality Risk of Community-Dwelling Older Adults: A Population-Based Prospective Cohort Study

    Felipe M Santana1, Michel A Gonçalves2, Diogo S Domiciano3, Luana G Machado3, Jaqueline B Lopes3, Camille P Figueiredo3, Valéria Caparbo3, Liliam Takayama3 and Rosa M R Pereira4, 1Deparment of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Department of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil

    Background/Purpose:  Body composition changes resulting from ageing (decreased muscle mass and increased fat tissue) are frequently not accompanied by concomitant changes in body mass index…
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