Abstracts tagged "Elderly"

Abstract Number: 2176 • 2018 ACR/ARHP Annual Meeting
The Association of Gout with Incident Giant Cell Arteritis in Older Adults
Jasvinder A. Singh and John Cleveland, Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Giant cell arteritis (GCA) is a vasculitis that affects large and medium sized arteries in people 50 years or older. Gout, the most common…
Abstract Number: 2226 • 2018 ACR/ARHP Annual Meeting
Gout and the Risk of Incident Dementia in the Elderly: A Medicare Claims Study
Jasvinder A. Singh¹ and John Cleveland², ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The pursuit of a link between gout/hyperuricemia and dementia has led to contradictory results. Most observational studies, including population-based studies, showed that hyperuricemia was…
Abstract Number: 2324 • 2018 ACR/ARHP Annual Meeting
Predictors of Refracture in Patients with Hip Fragility Fracture
Sara Ganhão^1,2, Miguel Guerra³, Francisca Aguiar^1,2, Georgina Terroso¹, Romana Vieira³, Diana Gonçalves⁴, Teresa Martins-Rocha^2,5, Raquel Ferreira^1,2, Ana Águeda^2,6, Tiago Meirinhos⁷, Eva Mariz^1,2, Raquel Lucas⁸, Miguel Bernardes^1,2, Carlos Vaz^1,2 and Lúcia Costa¹, ¹Rheumatology, Centro Hospitalar de São João, Oporto, Portugal, ²Faculty of Medicine, Oporto University, Oporto, Portugal, ³Rheumatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal, ⁴Rheumatology, Centro Hospitalar de Trás-os-Montes e Alto Douro, Vila Real, Portugal, ⁵Rheumatology Department, Centro Hospitalar de São João, Porto, Portugal, Oporto, Portugal, ⁶Rheumatology, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, ⁷Serviço de Reumatologia, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal, Aveiro, Portugal, ⁸Public Health, Centro Hospitalar de São João, Oporto, Portugal
Background/Purpose: Hip fractures are associated with substantially elevated morbidity and mortality and thus represent a serious public health problem. The purpose of this study is…
Abstract Number: 2409 • 2017 ACR/ARHP Annual Meeting
Older Age and Male Gender Are Independent Predictors of Quantiferon Positivity Among Adult Rheumatic Patients in a Tertiary Care Center from a BCG Vaccinated Country: Hur-BIO Single Center Real Life Results
Emrah Seyhoglu¹, Oguz Abdullah Uyaroglu¹, Abdulsamet Erden², Levent Kilic², Berkan Armagan², Alper Sari², Omer Karadag², Sule Apras Bilgen², Ali Akdogan², Ihsan Ertenli², Umut Kalyoncu² and Sedat Kiraz², ¹Internal Medicine, Hacettepe University Faculty of Medicine, Ankara, Turkey, ²Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey
Background/Purpose: TNF-α inhibitors increase the risk of emergence of active tuberculosis (TB). Screening rheumatic patients for latent TB is a necessity before initiation of biological…
Abstract Number: 2494 • 2017 ACR/ARHP Annual Meeting
Analysis of the Efficacy, Safety and Continuation Rate of Abatacept in Elderly Patients with Rheumatoid Arthritis
Mayumi Matsuda¹, Yu Funakubo Asanuma², Noritsune Kouzu³ and Toshihide Mimura², ¹Department of Rheumatology and Applied Immunology, Saitama Medical University, Moroyama-machi, Japan, ²Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, ³Saitama Medical University, Moroyama, Japan
Background/Purpose: The elderly rheumatoid arthritis (RA) patients have declined physical performances and various complications. The efficacy of the biological DMARDs may decrease in elderly RA…
Abstract Number: 303 • 2017 ACR/ARHP Annual Meeting
Outcomes after Hip Fracture in the Elderly: Does Social Isolation Matter?
Lisa A. Mandl¹, Omar Halawa², Jackie Szymonifka³, Kirsten Grueter⁴ and Joseph Lane⁵, ¹Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY, ⁴Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, ⁵Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY
Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
Abstract Number: 540 • 2017 ACR/ARHP Annual Meeting
Being Elderly Is Not a Predictive Factor of Discontinuation of Abatacept Due to Adverse Events in Rheumatoid Arthritis Patients with Concomitant Methotrexate: A Retrospective Observational Study Based on Data from a Japanese Multicenter Registry Study
Nobunori Takahashi, Toshihisa Kojima, Shuji Asai, Tatsuo Watanabe, Takuya Matsumoto, Nobuyuki Asai, Yasumori Sobue and Naoki Ishiguro, Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
Background/Purpose: Abatacept is a new class of biologic agent for the treatment of rheumatoid arthritis (RA) that inhibits T cell activation by binding to CD80/86.…
Abstract Number: 1770 • 2017 ACR/ARHP Annual Meeting
ANCA-Associated Vasculitis (AAV) in Younger Vs Older Patients: Comparison of Clinical, Serologic and Outcome Differences and Their Implications for Management
Priya Chokshi¹, Olufemi Aina², Naveed Masani², Melissa Fazzari³, Elise Belilos¹, Kristina Belostocki¹, Gary Rosenblum¹, Tobin Abraham⁴, Daniil Shimonov⁴, Zinal Patel⁴ and Steven E. Carsons¹, ¹Rheumatology, NYU Winthrop Hospital, Mineola, NY, ²Nephrology, NYU Winthrop Hospital, Mineola, NY, ³Biostatistics, NYU Winthrop Hospital, Mineola, NY, ⁴Medicine, NYU Winthrop Hospital, Mineola, NY
Background/Purpose: ANCA-associated vasculitis (AAV) is a cause of multi-organ disease in all ages, but peaks at ages 65-74. Limited data is available on the characteristics…
Abstract Number: 1852 • 2017 ACR/ARHP Annual Meeting
Validating Patient Reported Outcomes in Older Veterans with Chronic Back Pain
Rabih Nayfe¹, Matthieu Chansard², Thiru Annaswamy³, Katharine McCallister², Liana Fraenkel⁴, Eric Mortensen⁵ and Una E. Makris⁶, ¹Department of Medicine, UT Southwestern Medical Center, Dallas, TX, ²Clinical Sciences, UT Southwestern Medical Center, Dallas, TX, ³Physical Medicine & Rehabilitation,, VA North Texas Health Care System, Dallas, TX, ⁴Rheumatology, Rheumatology, Yale University School of Medicine, New Haven, CT, New Haven, CT, ⁵Department of Medicine, University of Connecticut, Farmington, CT, ⁶Department of Medicine, VA North Texas Health Care System, Dallas, TX
Background/Purpose: Chronic back pain is the second most common reason for a physician’s visit and results in significant physical and psychosocial consequences in older adults.…
Abstract Number: 1961 • 2017 ACR/ARHP Annual Meeting
Risk Factors for Low Muscle MASS in Community-Dwelling Older Women: A Population-Based Prospective Cohort Study in Brazil. the São Paulo Ageing & Health Study
Ketty Machado¹, Diogo S Domiciano², Luana G Machado³, Jaqueline B Lopes⁴, Camille P Figueiredo⁵, Valéria F. Caparbo³, Liliam Takayama³, Paulo Menezes⁶ and Rosa M R Pereira², ¹Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil, ³Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, ⁵Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil, ⁶Preventive medicine, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Sarcopenia is a syndrome characterized by progressive loss of skeletal muscle mass, which results in decreased muscle strength and impairment of functional capacity. Moreover,…
Abstract Number: 201 • 2016 ACR/ARHP Annual Meeting
Allopurinol Reduces the Risk of Myocardial Infarction (MI) in the Elderly: A Study of Medicare Claims
Jasvinder A. Singh¹ and Shaohua Yu², ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To assess whether allopurinol use reduces the risk of myocardial infarction (MI) in the elderly. Methods: We used the 2006-2012 5% random sample of…
Abstract Number: 1605 • 2016 ACR/ARHP Annual Meeting
Pooled Safety and Efficacy of Sarilumab in Rheumatoid Arthritis Patients 65 Years of Age and Older
Roy Fleischmann¹, Mark C. Genovese², Janet van Adelsberg³, Erin Mangan⁴, Melitza Iglesias-Rodriguez⁵, Deborah Dukovic⁶ and TWJ Huizinga⁷, ¹Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ²Stanford University Medical Center, Palo Alto, CA, ³Clinical Science, Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁴Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ⁵Sanofi Genzyme, Cambridge, MA, ⁶Sanofi Genzyme, Bridgewater, NJ, ⁷Leiden University Medical Centre, Leiden, Netherlands
Background/Purpose: Sarilumab is a human mAb blocking the IL-6Rα. Sarilumab (150 or 200 mg every 2 weeks [q2w] subcutaneously) + MTX demonstrated efficacy vs placebo…
Abstract Number: 1613 • 2016 ACR/ARHP Annual Meeting
Safe and Effective Tocilizumab Therapy in Elderly Patients with Rheumatoid Arthritis
Christof Specker¹, Jörg Kaufmann², Herbert Kellner³, Peter Kaestner⁴, Christoph Volberg⁵, Verena Braunewell⁶, Martin Aringer⁷, Maren Sieburg⁸, Lothar Meier⁹, Michael Hofmann¹⁰, Jan-Paul Flacke¹¹, Hans-Peter Tony¹² and Gerhard Fliedner¹³, ¹Rheumatology & Clinical Immunology, University Hospital Essen, Essen, Germany, ²Ambulant Centres for Rheumatology, Ludwigsfelde, Germany, ³Specialist Practice for Rheumatology and Gastroenterology, Munich, Germany, ⁴Outpatient department of Rheumatology, MVZ Ambulantes Rheumazentrum, Erfurt, Germany, ⁵Rheumazentrum Neuss, Neuss, Germany, ⁶Schwerpunktpraxis Rheumatologie, Moenchengladbach, Germany, ⁷Rheumatology, Medicine III, University Clinical Center Technical University of Dresden, Dresden, Germany, ⁸Rheumatologische Gemeinschaftspraxis, Magdeburg, Germany, ⁹Gemeinschaftspraxis für Innere Medizin - Rheumatologie, Hofheim am Taunus, Germany, ¹⁰Rheumatology, Chugai Pharma Europe Ltd., Frankfurt, Germany, ¹¹Rheumatology, Roche Pharma AG, Grenzach-Wyhlen, Germany, ¹²Rheumatology/Immunology, Medical Clinic II, University Clinic Wuerzburg, Würzburg, Germany, ¹³Internal Med/Rheumatology, Rheumatological Practice, Osnabrueck, Germany
Background/Purpose: The non-interventional study ICHIBAN was set up in 2010 to evaluate the effectiveness and safety of intravenously administered Tocilizumab (TCZ IV) in patients (pts)…
Abstract Number: 2672 • 2016 ACR/ARHP Annual Meeting
Elderly Patients Risk a False Positive Diagnosis of Primary Sjogren’s Syndrome If a Positive Labial Gland Biopsy Is Solely Based on Focus Score
Erlin A. Haacke^1,2, Jolien F. van Nimwegen¹, Martha S. van Ginkel¹, Suzanne Arends¹, Fred K.L. Spijkervet³, Gwenny M. Verstappen¹, Nicole Sillevis Smitt-Kamminga⁴, Arjan Vissink⁵, Frans G.M. Kroese¹, Bert van der Vegt⁶ and Hendrika Bootsma⁷, ¹Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ²Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ³Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁴Opthalmology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁵Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁶Pathology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁷Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic auto-immune disease affecting the exocrine glands leading to sicca complaints. For the diagnosis of pSS, a positive…
Abstract Number: 3070 • 2016 ACR/ARHP Annual Meeting
Effect of Sarcopenia, Subcutaneous Adipose Tissue and Abdominal Visceral Fat on Mortality Risk of Community-Dwelling Older Adults: A Population-Based Prospective Cohort Study
Felipe M Santana¹, Michel A Gonçalves², Diogo S Domiciano³, Luana G Machado³, Jaqueline B Lopes³, Camille P Figueiredo³, Valéria Caparbo³, Liliam Takayama³ and Rosa M R Pereira⁴, ¹Deparment of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Department of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Faculdade de Medicina da USP, São Paulo, Brazil
Background/Purpose: Body composition changes resulting from ageing (decreased muscle mass and increased fat tissue) are frequently not accompanied by concomitant changes in body mass index…

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