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Abstracts tagged "dry eyes and genomics"

  • Abstract Number: 1216 • ACR/ARHP Annual Meeting 2016

    Sjogren’s Syndrome-Associated Transcripts Show Correlation with Objective Measures of Dryness

    John A. Ice1, Indra Adrianto1, Astrid Rasmussen1, Kiely Grundahl2, Michelle L. Joachims3, Graham B. Wiley1, Jennifer A. Kelly1, Glen D. Houston4, David M. Lewis4, Lida Radfar5, Donald U. Stone6,7, Barbara M. Segal8, Nelson L. Rhodus9, Joel M. Guthridge3, James Chodosh10,11, Raj Gopalakrishnan12, Andrew J.W. Huang13, Pamela J Hughes14, Michael D. Rohrer15, Judith A. James1,16,17, Courtney G. Montgomery1, R. Hal Scofield1,17,18, Patrick Gaffney1, Kathy L. Sivils3 and Christopher J. Lessard1, 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Department of Oral and Maxillofacial Pathology, University of Oklahoma College of Dentistry, Oklahoma City, OK, 5Oral Diagnosis and Radiology Department, University of Oklahoma College of Dentistry, Oklahoma City, OK, 6King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia, 7Department of Ophthalmology, Johns Hopkins University, Baltimore, MD, 8Rheumatology, Hennepin County Medical Center, Minneapolis, MN, 9Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, MN, 10Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, 11Harvard Medical School, Boston, MA, 12Diagnostic and Biological Sciences, Division of Oral Pathology, University of Minnesota School of Dentistry, Minneapolis, MN, 13Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, MO, 14Department of Oral and Maxillofacial Surgery, Oregon Health & Science University School of Dentistry, Portland, OR, 15Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, MN, 16Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 17Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 18US Department of Veterans Affairs Medical Center, Oklahoma City, OK

    Background/Purpose: Sjögren’s syndrome (SS) is a chronic autoimmune disorder in which exocrine dysfunction can lead to chronic, debilitating dryness. Expression studies in SS have identified…

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