ACR Meeting Abstracts

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Abstracts tagged "Disease-modifying antirheumatic drugs"

  • Abstract Number: 548 • 2018 ACR/ARHP Annual Meeting

    Persistence in Low Disease Activity or Remission with Etanercept Monotherapy in Patients with Rheumatoid Arthritis: Results from the Corrona Registry

    Dimitrios A. Pappas1, Ying Shan2, Tamara Lesperance3, Sabrina Rebello2, Elaine Karis4, Greg Kricorian4, Winnie Hua5, Neil A. Accortt4 and Scott Stryker4, 1Corrona LLC, Waltham, MA, 2Corrona, LLC, Southborough, MA, 3DOCS Global, Inc., North Wales, PA, 4Amgen Inc., Thousand Oaks, CA, 5Corrona, LLC, Waltham, MA

    Background/Purpose:  Monotherapy with etanercept (ETN) may be a viable therapeutic option for maintenance of patients with rheumatoid arthritis (RA) who prefer to eliminate potential burdens…
  • Abstract Number: 979 • 2018 ACR/ARHP Annual Meeting

    Stopping Medicines for Inactive Juvenile Idiopathic Arthritis: What Do Patients and Families Consider?

    Daniel B. Horton1,2, Jomaira Salas3, Aleksandra Wec4, Timothy Beukelman5, Alexis Boneparth6, Jaime Guzman7, Ky Haverkamp8, Melanie Kohlheim9, Melissa L. Mannion5, Nandini Moorthy1, Elizabeth Stringer10, Lori Tucker7, Sarah Ringold11 and Marsha Rosenthal2, 1Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2Rutgers Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, 3Department of Sociology, Rutgers, the State University of New Jersey, New Brunswick, NJ, 4Mathematica Policy Research, Princeton, NJ, 5Pediatrics, University of Alabama at Birmingham, Birmingham, AL, 6Pediatrics, Columbia University Medical Center, New York, NY, 7Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, 8Family Medicine, University of Washington School of Medicine, Seattle, WA, 9Pediatric Rheumatology Care and Outcomes Improvement Network, Cincinnati, OH, 10IWK Health Centre, Dalhousie University, Halifax, NS, Canada, 11Pediatrics, Seattle Children's Hospital, Seattle, WA

    Background/Purpose: Prior research has focused on factors important to clinicians in decisions about withdrawing JIA therapy. Based on recent interviews with patients and caregivers about…
  • Abstract Number: 1036 • 2018 ACR/ARHP Annual Meeting

    Effects of Three Potential Anabolic Disease-Modifying Osteoarthritis Drugs – Sprifermin, Insulin-like Growth Factor 1 and Bone Morphogenetic Protein 7 – on Matrix Production and the Phenotype of Articular Chondrocytes

    Sylvia Muller, Martin Michaelis, Sven Lindemann and Anne Gigout, Merck KGaA, Darmstadt, Germany

    Background/Purpose: Disease-modifying osteoarthritis drugs with an anabolic mode of action should stimulate the growth of new hyaline cartilage. For instance, recombinant human fibroblast growth factor…
  • Abstract Number: 2142 • 2018 ACR/ARHP Annual Meeting

    Exposure to Disease Modifying Antirheumatic Drugs during Pregnancy in Women with Inflammatory Arthritis and the Risk of Serious Maternal Infection: A Population-Based Cohort Study

    Mary A. De Vera1,2,3, Nicole W. Tsao1,2,3, Eric C. Sayre2 and Alyssa Howren1,2,3, 1Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Canada, Richmond, BC, Canada, 3Collaboration for Outcomes Research and Evaluation (CORE), Vancouver, BC, Canada

    Background/Purpose: Infection risk is one of the concerns regarding therapy with conventional disease modifying antirheumatic drugs (csDMARDs) and to our knowledge no research has examined…
  • Abstract Number: 2368 • 2018 ACR/ARHP Annual Meeting

    Patient Preferences for Disease Modifying Anti-Rheumatic Drug Treatment in Rheumatoid Arthritis: A Systematic Review

    Caylib Durand1, Maysoon Eldoma1, Deborah A. Marshall2 and Glen Hazlewood1,3, 1Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2Community Health Sciences, University of Calgary, Calgary, AB, Canada, 3Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada

    Background/Purpose: Treatment choices in rheumatoid arthritis (RA) involve trade-offs in risks, benefits and other considerations such as dosing. Understanding patient preferences for these trade-offs is…
  • Abstract Number: 2861 • 2018 ACR/ARHP Annual Meeting

    Clinical Laboratory Telephone Communication Outreach to Rheumatology Patients Improves Guideline-Concordant Timeliness of Monitoring of Conventional and Biologic Disease-Modifying Anti-Rheumatic Drugs (DMARDs)

    Tyson Hagen1, Bharati Bhardwaja2, David Silverman3, Susan Shetterly4 and Marsha Raebel5, 1Rheumatology, Kaiser Permanente Colorado, Lafayette, CO, 2Pharmacy, Kaiser Permanente Colorado, Lafayette, CO, 3Kaiser Permanente Colorado, La Fayette, CO, 4Institute for health Research, Kaiser Permanente Colorado, Aurora, CO, 5Institute for Health Research, Kaiser Permanente Colorado, Aurora, CO

    Background/Purpose: The American College of Rheumatology has published guidelines for laboratory monitoring of conventional DMARDs (cDMARDs). At Kaiser Permanente Colorado (KPCO), although most patients eventually…
  • Abstract Number: 2275 • 2017 ACR/ARHP Annual Meeting

    Factors Related to Sustained Discontinuation of Medications for Well-Controlled JIA in the Childhood Arthritis & Rheumatology Research Alliance Registry

    Daniel B. Horton1, Fenglong Xie2, Melissa L. Mannion3, Sarah Ringold4, Colleen K. Correll5, Anne C. Dennos6 and Timothy Beukelman7, 1Rutgers Biomedical and Health Sciences, New Brunswick, NJ, 2Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Pediatric rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4Seattle Children's Hospital, Seattle, WA, 5Pediatrics, University of Minnesota, Minneapolis, MN, 6Duke Clinical Research Institute, Durham, NC, 7Pediatrics, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Stopping medications is a priority for many patients with well-controlled JIA, but few factors predict favorable outcomes after discontinuation. We examined factors associated with…
  • Abstract Number: 2782 • 2017 ACR/ARHP Annual Meeting

    Patient Beliefs and Preference to Initiate a Proposed Medication in Rheumatoid Arthritis

    Richard W Martin1, Rohit Nallani2, Andrew D Head1, Aaron T Eggebeen1, James D Birmingham1 and Eric T Slavin1, 1Medicine, Rheumatology, Michigan State University, College of Human Medicine, Grand Rapids, MI, 2Michigan State University, College of Human Medicine, Grand Rapids, MI

    Background/Purpose : Normative economic theory assumes that people making decisions have complete information of the options, rationally weigh the opportunity costs, expected outcomes and optimize…
  • Abstract Number: 122 • 2017 ACR/ARHP Annual Meeting

    Poor Prognostic Factors at the Start of Methotrexate Therapy Are Not Associated with Worse Treatment Response: Results from the Rheumatoid Arthritis Medication Study

    JM Gwinnutt1, Kimme L. Hyrich1, M Lunt1, Darren Plant1, M Brazil2, R Postema2, Anne Barton1 and Suzanne M Verstappen1, 1Manchester Academic Health Science Centre, Manchester, United Kingdom, 2Bristol-Myers Squibb, Uxbridge, United Kingdom

    Background/Purpose: As anti-citrullinated protein antibody positivity (+), RF+ and erosions are independently associated with poor outcomes in patients (pts) with RA, clinicians may use these…
  • Abstract Number: 448 • 2017 ACR/ARHP Annual Meeting

    Predicting Remission at 6 Months in Early Rheumatoid Arthritis Treated with Conventional Synthetic Dmards

    Michael D Wiese1, Robert Metcalf2, Mihir D Wechalekar3, Llew Spargo2, Leah McWilliams4, Michael James4,5, Catherine Hill6 and Susanna Proudman7, 1School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia, 2Rheumatology Unit, Royal Adelaide Hospital, South Australia, Adelaide, Australia, 3Royal Adelaide Hospital, Adelaide, Australia, 4Department of Rheumatology, Royal Adelaide Hospital, Adelaide, Australia, 5Department of Medicine, University of Adelaide, Adelaide, Australia, 6The Queen Elizabeth Hospital, Adelaide, Australia, 7University of Adelaide, Adelaide, Australia

    Background/Purpose: Initial treatment of RA with triple csDMARD therapy can achieve remission in a proportion of patients. Others respond poorly yet must wait at least…
  • Abstract Number: 538 • 2017 ACR/ARHP Annual Meeting

    Severe Adverse Drug Reactions Due to Disease Modifying Drugs in Patients with Incident Rheumatoid Arthritis

    Lydia A Alcazar1, Judit Font Urgelles2, Cynthia Milagros León Cárdenas2, Cristina Vadillo Font2, Dalifer Freites Núñez1, Leticia Leon1, Juan A Jover Jover2 and Zulema Rosales Rosado1,2, 1Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, 2Rheumatology, Hospital Clínico San Carlos, Madrid, Spain

    Background/Purpose: There is a well-known risk of developing adverse drug reactions (ADR) in rheumatology due, mainly, to the Disease Modifying Drugs (DMARD) used. It is…
  • Abstract Number: 1313 • 2017 ACR/ARHP Annual Meeting

    Oral Corticosteroid Use during Pregnancy and Risk of Preterm Birth in Women with Rheumatoid Arthritis

    Kristin Palmsten1, Gretchen Bandoli2, Diana L Johnson1, Ronghui Xu3,4 and Christina D Chambers1, 1Department of Pediatrics, University of California, San Diego, La Jolla, CA, 2Pediatrics, University of California, San Diego, La Jolla, CA, 3Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, 4Department of Mathematics, University of California, San Diego, La Jolla, CA

    Background/Purpose: There are limited data regarding gestational timing of oral corticosteroid (OCS) use during pregnancy and risk of preterm birth. The objective was to compare…
  • Abstract Number: 1385 • 2017 ACR/ARHP Annual Meeting

    Decisional Conflict in Doctor – Patient Discussions about Disease Modifying Anti-Rheumatic Drugs

    Rohit Nallani1 and Richard W Martin2, 1Michigan State University, College of Human Medicine, Grand Rapids, MI, 2Medicine, Rheumatology, Michigan State University, College of Human Medicine, Grand Rapids, MI

    Background/Purpose: There are few published studies describing patient-physician discussions about initiating new rheumatoid arthritis (RA) medications in real world settings. The purpose of this study…
  • Abstract Number: 1443 • 2017 ACR/ARHP Annual Meeting

    Adverse Drug Reactions Due to Disease Modifying Drugs in a Cohort of Patients with Incident Rheumatoid Arthritis

    Zulema Rosales Rosado1,2, Dalifer Freites Núñez2, Cristina Lajas Petisco1, Esperanza Pato Cour1, Leticia Leon2, Judit Font Urgelles1, Juan A Jover Jover1 and Lydia A Alcazar2, 1Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 2Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain

    Background/Purpose: There is a well-known risk of developing adverse drug reactions (ADR) in rheumatology due, mainly, to the Disease Modifying Drugs (DMARD) used. After more…
  • Abstract Number: 1469 • 2017 ACR/ARHP Annual Meeting

    Treatment Paradigms in Real-World Practice: Biologic Agent Use Prior to and after Discontinuation of Abatacept

    Rieke Alten1, H-M Lorenz2, X Mariette3, H Nüßlein4, M Galeazzi5, F Navarro6, M Chartier7, Y Elbez8, C Rauch9 and M Le Bars7, 1Schlosspark-Klinik University Medicine, Berlin, Germany, 2University Hospital, Heidelberg, Germany, 3Université Paris-Sud, Paris, France, 4University of Erlangen-Nuremberg, Nuremberg, Germany, 5University of Siena, Siena, Italy, 6Hospital Universitario Virgen Macarena, Seville, Spain, 7Bristol-Myers Squibb, Rueil-Malmaison, France, 8Excelya, Boulogne-Billancourt, France, 9Bristol-Myers Squibb, Munich, Germany

    Background/Purpose: ACTION is a 2-year, observational study of patients (pts) with moderate-to-severe RA who initiated IV abatacept in Canada and Europe (NCT02109666). The objective was…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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