Abstracts tagged "Disease Activity"

Abstract Number: 2879 • 2013 ACR/ARHP Annual Meeting
Prognostic Value Of Minor Salivary Gland Assessments In Primary Sjögren’s Syndrome
Anna Risselada¹, A.a. Kruize², J.A.G. van Roon³, F.P.J.G. Lafeber⁴ and J.W.J. Bijlsma⁴, ¹Clinical immunology and Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ²Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ³Rheumatology & Clinical Immunology/Lab Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Salivary gland assessment is important for diagnosing primary Sjögren’s syndrome (pSS), as the lymphocytic focus score (LFS) is part of pSS classification criteria. Quantitative…
Abstract Number: 2511 • 2013 ACR/ARHP Annual Meeting
Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification
Majed M. Khraishi¹, Rana Aslanov², Sanjay Dixit³, Krista Fudge⁴, Vandana Ahluwalia⁵ and Sarah Khraishi⁶, ¹Nexus Clinical Research, St John's, NF, Canada, ²Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada, ⁵Past President, Ontario Rheumatology Association, Brampton, ON, Canada, ⁶Nexus Clinical Research, Memorial University of Newfoundland, St.John's, NF, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic immune modulated disease with variable clinical manifestations. New advances in the management of SLE mandated closer monitoring…
Abstract Number: 2241 • 2013 ACR/ARHP Annual Meeting
Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort
Susan J. Bartlett^1,2, Clifton O. Bingham III³, Ernest Choy⁴, Juan Xiong⁵, Gilles Boire⁶, Boulos Haraoui⁷, Janet E. Pope^8,9, J. Carter Thorne¹⁰, Carol A. Hitchon¹¹, Diane Tin¹², Edward C. Keystone¹³ and Vivian P. Bykerk^13,14, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁷Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ⁸St Joseph Health Care, London, ON, Canada, ⁹Univ of Western Ontario, London, ON, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ¹⁴Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) flares are common, poorly defined, and understudied. A tool is needed to measure significant RA flares that may signal need for…
Abstract Number: 1667 • 2013 ACR/ARHP Annual Meeting
Serum S100A8/S100A9 and S100A12 As a Marker Of Disease Activity In Giant Cell Arteritis
Jason Springer¹, Dirk Holzinger², Gary S. Hoffman³, Paul A. Monach⁴, Thomas Hamilton⁵, Carol A. Langford⁶, Dirk Foell⁷, David Cuthbertson⁸, Colin O'Rourke⁹, Simon Carette¹⁰, Nader A. Khalidi¹¹, Carol McAlear¹², Christian Pagnoux¹⁰, Philip Seo¹³, Kenneth J. Warrington¹⁴, Steven R. Ytterberg¹⁵, Thomas Vogl¹⁶, Peter A. Merkel¹⁷, Johannes Roth¹⁸ and Rula Hajj-Ali¹⁹, ¹Division of Allergy, Clinical Immunology and Rheumatology, University of Kansas Medical Center, Kansas City, KS, ²Institute of Immunology, University Muenster, Muenster, Germany, ³Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ⁴Rheumatology, Boston University, Boston, MA, ⁵Cleveland Clinic, Cleveland, OH, ⁶Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ⁷Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ⁸Department of Biostatistics, University of South Florida, Tampa, FL, ⁹Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ¹⁰Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ¹¹Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, ¹²University of Pennsylvania, Philadelphia, PA, ¹³Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ¹⁴Division of Rheumatology, Mayo Clinic, Rochester, MN, ¹⁵Rheumatology Division, Mayo Clinic, Rochester, MN, ¹⁶Institute of Immunology, University of Muenster, Muenster, Germany, ¹⁷Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, ¹⁸Immunology, Institute of Immunology University of Muenster, Muenster, Germany, ¹⁹Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: The S100 proteins (S100A8/9 complex and S100A12) are calcium binding proteins expressed during myeloid differentiation. S100 proteins are phagocyte-specific proteins that have been demonstrated…
Abstract Number: 1341 • 2013 ACR/ARHP Annual Meeting
Significantly Less Glucocorticoids and Better Patient-Reported Outcomes In Women With Early Inflammatory Arthritis Using Oral Contraceptives Compared To Never Users
Gisela Westhoff¹, Rainer H. Straub², Frank Buttgereit³, Johanna Callhoff⁴ and Angela Zink⁵, ¹Epidemiology Unit, German Rheumatism Research Center Berlin, Berlin, Germany, ²Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany, ³Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴German Rheumatism Research Center, Berlin, Germany, ⁵German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany
Background/Purpose: Data on the effects of oral contraceptives (OC) on the course of inflammatory arthritis (IA) are controversial. However, a recent analysis of data from…
Abstract Number: 792 • 2013 ACR/ARHP Annual Meeting
Methotrexate Polyglutamates in Erythrocytes Are Associated With Lower Disease Activity in Juvenile Idiopathic Arthritis Patients
Maja Bulatovic Calasan¹, Ethan den Boer², Maurits C.F.J. De Rotte³, S.J. Vastert⁴, Sylvia Kamphuis⁵, Robert De Jonge³ and Nico M. Wulffraat⁶, ¹Paediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ²Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, Netherlands, ³Clinical Chemistry, Erasmus Medical Center, Rotterdam, Netherlands, ⁴Pediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Pediatric Rheumatology, Eramus MC Sophia Children's Hospital, Rotterdam, Netherlands, ⁶Pediatric Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Methotrexate polyglutamates (MTX-PG) could be biomarkers of MTX response and adverse effects and could thus be used as a therapeutic drug monitoring (TDM) tool to steer tailor-made therapeutic…
Abstract Number: 306 • 2013 ACR/ARHP Annual Meeting
Responsiveness To Change Of a Global Ultrasound Assessment Score In Psoriatic Arthritis Patients
Maria Laura Acosta Felquer¹, Santiago Ruta¹, Javier Rosa², David A. Navarta³, Carla Saucedo¹, Ricardo Garcia-Monaco⁴, Mirtha Sabelli² and Enrique R. Soriano⁵, ¹Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Radiology and Imagenology Department, Hospital italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: Psoriatic arthritis (PsA) manifests clinically in several ways, including arthritis, enthesitis, and dactylitis,. Assessment of disease activity in PsA should ideally record each feature.…
Abstract Number: 2883 • 2013 ACR/ARHP Annual Meeting
Clinical Characteristics of Rheumatoid Arthritis Patients with Secondary Sjögren’s Syndrome and Association with Joint Damage
Lindsay E. Brown¹, Michelle A. Frits², Christine K. Iannaccone², Michael E. Weinblatt², Nancy A. Shadick³ and Katherine P. Liao⁴, ¹Internal Medicine, Massachusetts General Hospital, Boston, MA, ²Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ³Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Secondary Sjögren's syndrome (sSS) is a common extra-articular manifestation of rheumatoid arthritis (RA). However, the clinical characteristics of this subgroup of patients are not…
Abstract Number: 2456 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Overweight and Obesity and The Relation To Disease Activity, Physical Function and Quality Of Life In Patients With Axial Spondyloarthritis
Fiona Maas¹, Anneke Spoorenberg¹, Eveline van der Veer², Reinhard Bos³, Monique Efde³, Hendrika Bootsma⁴, Elisabeth Brouwer⁵ and Suzanne Arends^3,4, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ²Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, ³Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, ⁴Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ⁵Dept. of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Obesity is a growing problem in Western society. It is associated with an increased risk for many disorders, impaired functional capacity, and impaired quality…
Abstract Number: 2246 • 2013 ACR/ARHP Annual Meeting
Patients’ Assessment of the Disease Greatly Influences the Determination of Disease Activity and Remission in Rheumatoid Arthritis
Kenrin Shi^1,2, Kenji Miki^1,3, Masao Yukioka¹, Kosuke Ebina², Shoichi Kaneshiro² and Hideki Yoshikawa², ¹Department of Orthopaedic Surgery, Yukioka Hospital, Osaka, Japan, ²Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan, ³Department of Orthopaedic Surgery, Amagasaki Central Hospital, Amagasaki, Japan
Background/Purpose: Recently defined remission criteria of rheumatoid arthritis (RA), Boolean criteria or Simplified Disease Activity Index (SDAI)
Abstract Number: 1669 • 2013 ACR/ARHP Annual Meeting
The Birmingham Vasculitis Activity Score As a Measure Of Disease Activity In Patients With Giant Cell Arteritis
Tanaz A. Kermani¹, David Cuthbertson², Simon Carette³, Gary S. Hoffman⁴, Nader A. Khalidi⁵, Curry L. Koening⁶, Carol A. Langford⁷, Kathleen McKinnon-Maksimowicz⁸, Carol McAlear⁹, Paul A. Monach¹⁰, Philip Seo¹¹, Kenneth J. Warrington¹², Steven R. Ytterberg¹³, Peter A Merkel¹⁴ and Eric L. Matteson¹⁵, ¹Rheumatology, University of California Los Angeles, Los Angeles, CA, ²Department of Biostatistics, University of South Florida, Tampa, FL, ³Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ⁴Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ⁵Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, ⁶Internal Medicine, Salt Lake City Veterans Administration, Salt Lake City, UT, ⁷Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ⁸Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁹University of Pennsylvania, Philadelphia, PA, ¹⁰Rheumatology, Boston University, Boston, MA, ¹¹Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ¹²Division of Rheumatology, Mayo Clinic, Rochester, MN, ¹³Rheumatology Division, Mayo Clinic, Rochester, MN, ¹⁴Division of Rheumatology, University of Pennsylvania and VA Medical Center, Philadelphia, PA, ¹⁵Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: To evaluate the performance of the Birmingham Vasculitis Activity Score (BVAS), a validated tool for assessment of vasculitis disease activity, in a cohort…
Abstract Number: 1343 • 2013 ACR/ARHP Annual Meeting
Are There Differences Between Young and Older Onset Early Rheumatoid Arthritis and Does This Impact Outcomes? An Analysis From The Canadian Early Arthritis Cohort
Michael Arnold¹, Vivian P. Bykerk², Gilles Boire³, Boulos Haraoui⁴, Carol A. Hitchon⁵, J. Carter Thorne⁶, Edward Keystone⁷ and Janet E. Pope⁸, ¹Medicine/Rheumatology, University College Dublin, Ireland, Dublin, Ireland, ²Divison of Rheumatology, Hospital for Special Surgery, New York, NY, ³Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology, Institut de Rhumatologie de Montréal, Montreal, QC, Canada, ⁵Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ⁶Southlake Regional Health Centre, Newmarket, ON, Canada, ⁷Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, ⁸Medicine, Divsion of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada
Background/Purpose: To determine the impact of age on disease and remission in early rheumatoid arthritis (ERA). Methods: Data from the Canadian Early Arthritis Cohort (CATCH)…
Abstract Number: 798 • 2013 ACR/ARHP Annual Meeting
Targeting Ultrasound Remission In Early Rheumatoid Arthritis – Results Of The Taser Study
James Dale¹, Anne Stirling², Iain B. McInnes¹ and Duncan Porter³, ¹Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Gartnavel General Hospital, Glasgow, United Kingdom, ³Rheumatology, Gartnavel General Hospital, Glasgow, United Kingdom
Background/Purpose: The TaSER study (NCT00920478) is an open label randomized clinical trial with blinded assessments of outcome. It was designed to test whether the efficacy…
Abstract Number: 219 • 2013 ACR/ARHP Annual Meeting
Contrast-Enhanced Ultrasound Of The Sovraortic Arteries: The Potential Role In Monitoring Disease Activity and Response To Treatment In Large Vessel Vasculitis
Giuseppe Germanò¹, Pierluigi Macchioni¹, Niccolò Possemato² and Carlo Salvarani³, ¹Rheumatology Service, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ²S.C. Reumatologia, Arcispedale Santa Maria Nuova, I.R.C.C.S., Reggio Emilia, Italy, ³Rheumatology, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy
Background/Purpose: promising data has been recently published about the role of contrast-enhanced ultrasound (CEU) in the diagnosis and follow up of Takayasu arteritis (TA) -1,2-…
Abstract Number: 2869 • 2013 ACR/ARHP Annual Meeting
Changes In Patient-Reported Joint Counts and Composite Indices Can Identify Flare Of Disease Activity In Recent Onset Rheumatoid Arthritis
Karen Visser¹, Susan J. Bartlett^2,3, Clifton O. Bingham III⁴, Ernest Choy⁵, Daming Lin⁶, Juan Xiong⁷, Gilles Boire⁸, Boulos Haraoui⁹, Carol A. Hitchon¹⁰, Edward Keystone¹¹, Janet E. Pope¹², J. Carter Thorne¹³, Diane Tin¹⁴ and Vivian P. Bykerk¹⁵, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Epidemiology, McGill University, Montreal, QC, Canada, ³Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Division of Rheumatology, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁶Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁷Mount Sinai Hospital, Toronto, ON, Canada, ⁸Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁹Department of Medicine, Centre Hospitalier de l’Université de Montréal, Montréal, QC, Canada, ¹⁰Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹¹Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, ¹²St Joseph Health Care, London, ON, Canada, ¹³Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁴The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁵Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Patient-reported joint counts (JCs) have been identified as core domains for assessment of flare in rheumatoid arthritis (RA).[1] To assess the responsiveness and discriminative…

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