Abstracts tagged "Disease Activity"

Abstract Number: 731 • 2015 ACR/ARHP Annual Meeting
Damage and Mortality in SLE: Cluster Analysis of Patients from SLE Registry from the Spanish Society for Rheumatology (RELESSER)
JM Pego-Reigosa^1,2, Ana Lois-Iglesias^3,4, Francisco Javier Lopez Longo⁵, María Galindo⁶, J Calvo-Alen⁷, Jacobo de Uña⁸, Vanessa Balboa⁹, Alejandro Olivé¹⁰, Coral Mouriño-Rodríguez¹, Maria Teresa Oton Sanchez¹¹, Jesus Ibañez¹², Maria Loreto Horcada¹³, Ana Sánchez Atrio¹⁴, Carlos Alberto Montilla Morales¹⁵, Rafael-Benito Melero González¹, Ricardo Blanco¹⁶, Elvira Diez Alvarez¹⁷, Monica Fernandez Castro¹⁸, Esther Ruiz Lucea¹⁹, José Hernández Beiraín²⁰, Marian Gantes²¹, Blanca Hernández-Cruz²², Angela Pecondon-Español²³, Nuria Lozano-Rivas²⁴, Gema Bonilla²⁵, Vicente Torrente-Segarra²⁶, Iñigo Rúa-Figueroa²⁷ and RELESSER EASSER Group, ¹Rheumatology, EOXI Vigo, Vigo, Spain, ²Rheumatology, Instituto de Investigación Biomédica de Vigo(IBIV), Vigo, Spain, ³Rheumatology, Hospital Ntra Señora de La Esperanza, Santiago de Compostela, Spain, ⁴Rheumatology, University A Coruña, A Coruña, Spain, ⁵Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ⁶Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain, ⁷Rheumatology, Hospital de Sierrallana, Torrelavega, Spain, ⁸Statistics and OR, Vigo University, Vigo, Spain, ⁹Statistics and OR, Viho University, Vigo, Spain, ¹⁰Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, ¹¹Rheumatology, Hospital of Torrejón, Madrid, Spain, ¹²Rheumatology, Hospital Povisa, Vigo, Spain, ¹³Rheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain, ¹⁴University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ¹⁵Rheumatology, Hospital Universitario de Salamanca, Salamanca, Spain, ¹⁶Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ¹⁷Rheumatology, Hospital de León, León, Spain, ¹⁸Rheumatology, Hospital Puerta de Hierro, Madrid, Spain, ¹⁹Rheumatology, Hospital de Basurto, Bilbao, Spain, ²⁰Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, ²¹Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, ²²Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, ²³Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, ²⁴Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, ²⁵Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, ²⁶Hospital General Hospitalet-Sant Joan Despí Moisès Broggi, Hospitalet Llobregat, Barcelona, Spain, ²⁷Rheumatology, Hospital Universitario Dr Negrín. Las Palmas, Las Palmas de Gran Canaria, Spain
Background/Purpose: Damage in SLE is associated with mortality. Not every damage manifestation is associated in the same way. Some studies were made assessing this relation…
Abstract Number: 1505 • 2015 ACR/ARHP Annual Meeting
Carotid Artery Atherosclerosis in Patients with Active Rheumatoid Arthritis: Predictors of Plaque Occurrence and Progression over 24 Weeks
Tatiana Nevskaya¹, Janet E. Pope², Lillian Barra³ and Grace Parraga⁴, ¹Medicine, Division of Rheumatology, University of Western Ontario, London, ON, Canada, ²University of Western Ontario, London, ON, Canada, ³Medicine, Division of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ⁴University of Western Ontario, Robarts Research Institute, London, ON, Canada
Background/Purpose: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). Methods: Carotid arteries of RA patients were scanned…
Abstract Number: 1987 • 2015 ACR/ARHP Annual Meeting
Dramatic Efficacy of Tocilizumab As First Line Therapy in Patients with Recent Polymyalgia Rheumatica (PMR): Results of the First Longitudinal Prospective Study
Valerie Devauchelle¹, Alain Saraux², Jean-Marie Berthelot³, Divi Cornec⁴, Yves Renaudineau⁵, Sandrine Jousse-Joulin¹, Thierry Marhadour⁶, Solene Querellou⁷, Florent Garrigues⁸, Michel De Bandt⁹ and Maelenn Gouillou¹⁰, ¹Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ²Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ³Rheumatology, University Hospital, Nantes, France, ⁴Department of rheumatology, Brest Occidentale University, Brest, France, ⁵Immunology, Brest University Medical School Hospital, Brest, France, ⁶CHU La Cavale Blanche, Brest, France, ⁷Nuclear Medicine Department, Morvan University Hospital, Brest, France, ⁸Radiology department, Cavale Blanche Hospital and Brest Occidentale University, Brest, France, ⁹Rheumatology department, CHU Fort de France, Fort de France, France, ¹⁰Clinical Investigation Centre (CIC) 1412, CHU Cavale Blanche- Institut National de la Santé et de la Recherche Médicale (INSERM), Brest, France
Background/Purpose: Glucocorticoids (GCs) are the cornerstone treatment of polymyalgia rheumatica (PMR) but induce several adverse events. Methods: Objectives: To evaluate efficacy and safety of tocilizumab…
Abstract Number: 2531 • 2015 ACR/ARHP Annual Meeting
Hematologic Disorder during Pregnancy Associated with Adverse Pregnancy Outcomes Among Women with Systemic Lupus Erythematosus
Sara K. Tedeschi¹, Hongshu Guan², Alexander Fine², Bing Lu¹, Karen H. Costenbader¹ and Bonnie Bermas¹, ¹Rheumatology, Brigham & Women's Hospital, Boston, MA, ²Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Previous studies have found a relationship between overall systemic lupus erythematosus (SLE) activity and adverse pregnancy outcomes. We sought to investigate whether specific types…
Abstract Number: 2663 • 2015 ACR/ARHP Annual Meeting
Evaluation of Anti-Cyclic Citrullinated Peptide Autoantibody Levels in Clinical Practice and Its Association with Disease Activity
E Alemao¹, KK Gandhi¹, C Iannaccone², M Frits², JS Coblyn², N Shadick² and Michael Weinblatt², ¹Bristol-Myers Squibb, Princeton, NJ, ²Brigham and Women's Hospital, Boston, MA
Background/Purpose: Testing for anti-citrullinated peptide antibodies (ACPA) is included in the 2010 ACR classification criteria for RA. ACPA concentration, beyond ACPA positivity, is indicative of…
Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting
Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?
Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
Abstract Number: 158 • 2015 ACR/ARHP Annual Meeting
Ultrasound Score of Dominant Hand in Patients with Rheumatoid Arthritis Correlates with DAS28CRP, CDAI and SDAI but Not RAPID-3
Allen P. Anandarajah¹, Bethany Marston², Linda Grinnell-Merrick² and Ralf G. Thiele³, ¹Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, ²Rheumatology, University of Rochester Medical Center, Rochester, NY, ³University of Rochester Medical Center, Rochester, NY
Background/Purpose: Musculoskeletal ultrasound (MUS) allows for direct visualization of diverse pathologic features such as cortical bone erosions, synovial thickening, and synovial vascularity in the joints…
Abstract Number: 515 • 2015 ACR/ARHP Annual Meeting
Are Changes in Autoantibody Levels Reflecting Change in Prognosis of Rheumatoid Arthritis?
Manuel Unger¹, Farideh Alasti¹, Paul Studenic¹, Josef S. Smolen^2,3 and Daniel Aletaha¹, ¹Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ²2nd Department of Medicine, Hietzing Hospital, Vienna, Austria, ³Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria
Background/Purpose: The presence of rheumatoid factor (RF) and antibodies against citrullinated peptides (ACPA) is associated with progression of joint damage in patients with rheumatoid arthritis…
Abstract Number: 734 • 2015 ACR/ARHP Annual Meeting
Disease Patterns, Flare Incidence and Organ Damage Among Filipino Patients with Systemic Lupus Erythematosus: a One-Year Observational Study
Mary Flor Joy Edar, Leonid Zamora, Catherine Macapagal and Sandra V. Navarra, Rheumatology, University of Santo Tomas Hospital, Manila, Philippines
Background/Purpose: This study describes the disease patterns, flare incidence, hospitalizations and causes of mortality in a cohort of Filipino patients with systemic lupus erythematosus (SLE),…
Abstract Number: 1544 • 2015 ACR/ARHP Annual Meeting
Resiliency As a Predictor of Depressive Symptoms in Patients with Rheumatoid Arthritis
Matt Woo¹, Nadil Zeiadin¹, Hayley Yurgan², Dean Tripp³ and Mala Joneja¹, ¹Medicine, Queen's University, Kingston, ON, Canada, ²Psychology, Queen's University, Kingston, ON, Canada, ³Psychology, Anaesthesiology, Urology, Queen's University, Kingston, ON, Canada
Background/Purpose: Rheumatoid arthritis is a chronic, systemic, autoimmune disease affecting 0.5 – 1% of the adult population that leads to a progressive decline in functional…
Abstract Number: 2066 • 2015 ACR/ARHP Annual Meeting
Elevated Innate, Adaptive, and TNF-Superfamily Soluble Inflammatory Mediators Mark Impending Disease Flare, While Regulatory Mediators Distinguish Lack of Impending Disease Flare in African-American SLE Patients with Active Disease
Melissa E. Munroe¹, Evan G. Vista², Joan T. Merrill³, Joel M. Guthridge¹, Virginia C. Roberts¹ and Judith A. James⁴, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Rheumatology and Clinical Immunology, University of Santo Tomas, Taguig City, Philippines, ³Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Arthritis and Clinical Immunology, University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: SLE is a multifaceted disease characterized by immune dysregulation and varied disease activity. Identifying mechanistic mediators of altered disease activity would help prevent damage…
Abstract Number: 2532 • 2015 ACR/ARHP Annual Meeting
Disease Activity in Women with Systemic Lupus Erythematosus during Pregnancy and the First Year Post Partum
Carina Gotestam Skorpen^1,2, Johan Skomsvoll³, Inge-Margrethe Gilboe⁴, Stian Lydersen⁵ and Marianne Wallenius³, ¹Dept of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway, ²Dept of Rheumatology, Trondheim University Hospital, Norwegian National Advisory Unit on Pregnancy and Rheumatic Diseases, Trondheim, Norway, ³Dept of Rheumatology, Trondheim University Hospital, National Advisory Unit on Pregnancy and Rheumatic Diseases, Trondheim, Norway, ⁴Revmatologisk avdeling seksjon, Oslo universitetssykehus HF, Rikshospitalet, Oslo, Norway, ⁵Regional Center for the health of children and adolescents, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
Disease Activity in women with SLE during pregnancy and the first year post partumBackground/Purpose: Disease activity measured by validated methods has been sparsely examined during…
Abstract Number: 2672 • 2015 ACR/ARHP Annual Meeting
Determinants of Patient- Physician Discordance in Assessment of Global Disease Activity in Latinos with Rheumatoid Arthritis in the United States
George A. Karpouzas¹, Taylor Draper², Elizabeth Hernandez¹ and Sarah Ormseth¹, ¹Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Psychology, Loma Linda University, Loma Linda, CA
Background/Purpose: Patients and physicians often differ in their perceptions of disease activity in Rheumatoid arthritis (RA) as described by patients' and evaluators' global assessments (PGA…
Abstract Number: 3058 • 2015 ACR/ARHP Annual Meeting
NMR-Based Metabolomics Provides New Insights into the Inflammatory Processes in Takayasu Arteritis
Ramnath Misra¹, Anupam Guleria², Durga Prasanna Misra¹, Avadesh Pratap³, Durgesh Dubey⁴, Atul Rawat⁴, Smriti Chaurasia³, C L Khetrapal⁴, Dinesh Kumar⁴ and Paul Bacon⁵, ¹Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Centre of Biomedical Research, Lucknow, India, ³S.G.P.G.I.M.S, Department of Clinical Immunology, Lucknow, India, ⁴Centre for Biomedical Research, Lucknow, India, ⁵Rheumatology, Birmingham Universit, Birmingham, United Kingdom
Background/Purpose: Takayasu Arteritis (TA), a large vessel disease of unknown aetiology, is the orphan of the inflammatory vasculitides with no evidence base for therapy. It…
Abstract Number: 169 • 2015 ACR/ARHP Annual Meeting
Ultrasonographic Signs of Inflammation of Metatarsophalangeal Joints in Rheumatoid Arthritis Patients Who Are Treated to Target
Myrthe van der Ven¹, David F. Ten Cate², Andreas Gerards³, Johannes Jacobs⁴, Nanno Swen⁵, M.H. de Jager⁶, Natalja Basoski⁷, Cees Haagsma⁸, Mieke Hazes¹ and J.J. Luime¹, ¹Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ²Department of Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Vlietland Hospital, Schiedam, Netherlands, ⁴Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Rheumatology, Medical Center Alkmaar, Alkmaar, Netherlands, ⁶Department of Rheumatology, Albert Schweitzer Hospital, Dordrecht, Netherlands, ⁷Rheumatology, Maasstadziekenhuis, Rotterdam, Netherlands, ⁸Rheumatology, Ziekenhuisgroep Twente, Almelo, Netherlands
Background/Purpose: The feet are often involved in rheumatoid arthritis (RA), but physical examination of the metatarsophalangeal (MTP) joints to detect arthritis is challenging especially in…

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