ACR Meeting Abstracts

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Abstracts tagged "Disease Activity"

  • Abstract Number: 2608 • 2015 ACR/ARHP Annual Meeting

    The “Rheumatoid Arthritis Impact of Disease”� Score Correlates with Other Patient Reported Outcomes and with Disease Activity Scores in Patients with RA and Its Patient Acceptable Symptom State Is More Stringent Than DAS28-Remission

    Ricardo J.O. Ferreira1,2, Cátia Duarte1,3, Sylvie Batista3, Catarina Medeiros3, J.P. Sousa3, Gisela Eugénio1, Carlos Costa1, Pedro Carvalho1, Joana F. Ferreira1, Margarida Coutinho1,4, Maria J. Salvador1,4, Laure Gossec5 and J.A.P. da Silva3,6, 1Rheumatology, Centro Hospitalar e Universitário de Coimbra - Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal, 2Health Sciences Research Unit: Nursing (UICISA: E), Coimbra, Portugal, 3Faculty of Medicine, Universidade de Coimbra, Coimbra, Portugal, 4Clínica Universitária de Reumatologia, Faculty of Medicine, Universidade de Coimbra, Coimbra, Portugal, 5Rheumatology, Pitié Salpetriere Hospital, Paris, France, 6Centro Hospitalar e Universitário de Coimbra - Hospitais da Universidade de Coimbra, EPE, Coimbra, Portugal

    Background/Purpose: The "Rheumatoid Arthritis Impact of Disease" (RAID) score is a Patient Reported Outcome (PRO) that comprises seven domains of disease[1], that may reflect the…
  • Abstract Number: 2863 • 2015 ACR/ARHP Annual Meeting

    Discontinuation of Anti-TNF Therapy in Patients with Axial Spondyloarthritis. a Systematic Literature Review

    Victoria Navarro-Compán1, Chamaida Plasencia-Rodriguez2, Eugenio De Miguel1, Alejandro Balsa3, Emilio Martín-Mola1, Daniel Seoane-Mato4 and Juan D. Cañete5, 1Rheumatology, University Hospital La Paz, Madrid, Spain, 2Rheumatology Department, La Paz University Hospital-Rheumatology Department, Madrid, Spain, 3Rheumatology, La Paz University Hospital-Rheumatology Department, Madrid, Spain, 4Research Unit, Spanish Society of Rheumatology, Madrid, Spain, 5Rheumatology, Hospital Clinic and IDIBAPS, Barcelona, Spain

    Background/Purpose: In patients with axial spondyloarthritis (axSpA), anti-TNF therapy is successful for clinically improving signs and symptoms of the disease. However, there is no clear…
  • Abstract Number: 3184 • 2015 ACR/ARHP Annual Meeting

    Is Treat-to-Target Really Working? a Longitudinal Analysis in Biodam

    Sofia Ramiro1, Robert B.M. Landewé2, Désirée van der Heijde1, Oliver FitzGerald3, Mikkel Østergaard4,5, Joanne Homik6, Ori Elkayam7, J Carter Thorne8, Margaret Larche9, Gianfranco Ferraccioli10, Marina Backhaus11, Gilles Boire12, Bernard Combe13, Thierry Schaeverbeke14, Alain Saraux15, Maxime Dougados16, Silvano Adami17, Marcello Govoni18, Luigi Sinigaglia19, Alain G. Cantagrel20, Cornelia F. Allaart1, Cheryl Barnabe21, Clifton O. Bingham III22, Paul P. Tak23, Dirkjan van Schaardenburg24, Hilde Berner Hammer25, Rana Dadashova26, Edna Hutchings26, Joel Paschke26 and Walter Maksymowych27, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 3Rheumatology, St Vincent's University Hospital, Dublin, Ireland, 4Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, 5Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Glostrup, Denmark, 6Rheumatology, University of Alberta, Edmonton, AB, Canada, 7Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 8University of Toronto, Toronto, ON, Canada, 9Rheumatology, McMaster University, Hamilton, ON, Canada, 10Rheumatology and Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy, 11Rheumatology/Immunology, Charite University Hospital, Berlin, Germany, 12Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, 13Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, 14Rheumatology, Pellegrin University Hospital, Bordeaux, France, 15Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, 16Cochin Hospital, Paris Descartes University, Paris, France, 17University of Verona, Verona, Italy, 18University of Ferrara, Ferrara, Italy, 19Department of Rheumatology, Gaetano Pini Institute, Milan, Italy, 20Dept of Rheumatology, Centre Hospitalier Universitaire de Toulouse, Toulouse, France, 21Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 22Rheumatology, Johns Hopkins University, Baltimore, MD, 23Division of Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 24Rheumatology, Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, 25Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 26CaRE Arthritis, Edmonton, AB, Canada, 27Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: A Treat-to-Target approach (T2T), treating patients with RA towards a target, either remission or low disease activity (T2T-REM or T2T-LDA), is nowadays recommended. However…
  • Abstract Number: 405 • 2015 ACR/ARHP Annual Meeting

    Anti-C1q Antibodies As Potential Diagnostic and Prognostic Biomarkers in Juvenile Systemic Lupus Erythematosus

    Thaschawee Arkachaisri1,2, Justin Hung Tiong Tan1, Manasita Tanya1, Sook Fun Hoh3, Lena Das4 and Jing Yao Leong5,6, 1Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, 2Paediatrics, Duke-NUS Graduate Medical School, Singapore, Singapore, 3Nursing, KK Women's and Children's Hospital, Singapore, Singapore, 4Dept of Rheumatology, Cincinnati Children`s Hospital Medical Center, Cincinnati, OH, 5Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, 6SingHealth Translational Immunology and Inflammation Centre, Singapore Health Services Pte Ltd, Singapore, Singapore

    Background/Purpose: Anti-C1q antibodies (AC1q) were shown to strongly correlate with the occurrence and activity of lupus nephritis in adult SLE. Data of the antibodies in…
  • Abstract Number: 606 • 2015 ACR/ARHP Annual Meeting

    Impaired Kidney Function Improves Treatment Response after 6 Months of Methotrexat Treatment in Rheumatoid Arthritis Patients

    Paul Studenic1, Farideh Alasti1, Josef S. Smolen2,3, Helmuth Haslacher4 and Daniel Aletaha5, 1Department of Internal Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 2Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, 32nd Department of Medicine, Hietzing Hospital, Vienna, Austria, 4Laboratory Medicine, Medical University Vienna, Vienna, Austria, 5Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria

    Background/Purpose: Methotrexate (MTX) and leflunomide are categorized as DMARDs of first choice in treating rheumatoid arthritis patients. MTX should be used cautiously in patients with…
  • Abstract Number: 997 • 2015 ACR/ARHP Annual Meeting

    Feasibility and Influential Factors in Performing Self-Evaluation of DAS28 with Smart System of Disease Management (SSDM) By RA Patient in China

    Mu Rong1, Fei Xiao2, Chun Li3, Jianlong Guan4, Yan Shen4, Dongbao Zhao5, Xia Xu6, Lindi Jiang7, Huiyong Chen7, Li Su8, Yuhua Jia2, Li Zhang2, Yuan Liu2 and Zhan-Guo Li3, 1Department of Rheumatology and Immunology, People's Hospital, Beijing University Medical School, Beijing, China, 2Gothic Internet Technology Corporation, Shanghai, China, 3Department of Rheumatology & Immunology, People's Hospital, Beijing University Medical School, Beijing, China, 4Huadong Hospital Affiliated to Fudan University, Shanghai, China, 5ShangHai ChangHai Hospital, ShangHai ChangHai Hospital, ShangHai, China, 6Department of Rheumatology and Immunology, Changhai Hospital,Second Military Medical University,, Shanghai, China, 7Zhongshan Hospital, Fudan University, Shanghai, China, 8Longhua Hospital Shanghai University of TCM, Shanghai, China

    Background/Purpose: Regular evaluations of rheumatoid arthritis (RA) disease activities with disease activity score in 28 joints (DAS28) are critical steps to reach the goal of…
  • Abstract Number: 1689 • 2015 ACR/ARHP Annual Meeting

    Cross Sectional Study Investigating the Effect of the Presence of Fibromyalgia on Common Clinical Disease Activity Indices in Patients with Psoriatic Arthritis

    Shay Brikman1, Victoria Furer2, Yonatan Wolman3, Sara Borok Lev-Ran4, Ari Polachek5, Ofir Elalouf2, Amir Sharabi6, Ilana Kaufman1, Daphna Paran5 and Ori Elkayam6, 1Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, 3Medicine B, Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 4Tel Aviv Sourasky Medical Center, Tel AViv, Israel, 5Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 6Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Background/Purpose: To study the effect of the presence of fibromyalgia (FMS) on common clinical disease activity indices in patients with psoriatic arthritis (PsA). Methods: Seventy…
  • Abstract Number: 2479 • 2015 ACR/ARHP Annual Meeting

    The Association Between Social Networks, Disease Activity, and Pain in Rheumatoid Arthritis

    Taysir G. Mahmoud1, Christine Iannaccone2, Jing Cui2, Yvonne C. Lee3, Michael Weinblatt4 and N Shadick5, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, 3Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology, Immunology & Allergy, Brigham and Women's Hosp, Boston, MA

    The Association between Social Network, Disease Activity, and Pain in Rheumatoid ArthritisBackground/Purpose: Current research suggests that high social network status is related to lower levels…
  • Abstract Number: 2615 • 2015 ACR/ARHP Annual Meeting

    Changes in a Patient-Reported Measure of Physical Function, PF-10a, Are Most Strongly Associated with Changes in the Patient Global Assessment Portion of a Composite Measure of RA Disease Activity

    Elizabeth R. Wahl1,2, Andrew Gross2, Vladimir Chernitskiy2, Patricia P. Katz2 and Jinoos Yazdany3, 1Medicine/Rheumatology, San Francisco Veterans Affairs Medical Center, San Francisco, CA, 2Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 3University of California, San Francisco, San Francisco, CA

    Background/Purpose: A brief patient-reported measure of physical function, the PROMIS PF-10a, is sensitive to changes in disease activity among patients with rheumatoid arthritis (RA). However,…
  • Abstract Number: 2878 • 2015 ACR/ARHP Annual Meeting

    Treating Axial Spondyloarthritis to Target: Influence of the Population Characteristics and Comorbidities in Reaching Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Tnfalpha Inhibitors Agents

    Sara Monti, Veronica Codullo, Vittorio Grosso, Silvia Breda, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy

    Background/Purpose: The treat to target strategy (T2T), aiming at inactive disease (ID), has become the recommended approach also in the field of axial-SpA (axSpA) (1). …
  • Abstract Number: 3185 • 2015 ACR/ARHP Annual Meeting

    A Cluster-Randomized Trial of a Behavioral Intervention to Incorporate a Treat-to-Target Approach in the Clinical Care of Rheumatoid Arthritis Patients in the United States

    Leslie Harrold1,2, George W. Reed1,2, J. Timothy Harrington3, Christine J. Barr1, Katherine C. Saunders1, Allan Gibofsky4, Eric M. Ruderman5, Tmirah Haselkorn6, Jeffrey D. Greenberg1,7, Ani John6 and Joel M. Kremer8, 1Corrona, LLC, Southborough, MA, 2University of Massachusetts Medical School, Worcester, MA, 3Joiner Associates, LLC, Madison, WI, 4Hospital for Special Surgery, New York, NY, 5Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Genentech, Inc, South San Francisco, CA, 7NYU School of Medicine, New York, NY, 8Albany Medical College and The Center for Rheumatology, Albany, NY

    Background/Purpose: We report the results of a cluster-randomized behavioral intervention trial designed to assess the impact of implementing a treat-to-target (T2T) approach vs usual care…
  • Abstract Number: 409 • 2015 ACR/ARHP Annual Meeting

    Disease Activity, Disease Damage and Predictive Factors in Juvenile Onset Mixed Connective Tissue Disease – a Norwegian Nationwide Study

    Siri Opsahl Hetlevik1, Berit Flatø1,2, Marite Rygg3,4, Ellen Berit Nordal5 and Vibke Lilleby6, 1Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, 3Department of Pediatrics, St Olav University Hospital, Trondheim, Norway, 4Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, 5Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, 6Rheumatology, Oslo University Hospital, Oslo, Norway

    Background/Purpose: Mixed Connective Tissue Disease (MCTD) is a rare rheumatic disease with overlapping features from Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc) and Polymyositis. Juvenile…
  • Abstract Number: 620 • 2015 ACR/ARHP Annual Meeting

    Evaluation of Patients from the Non-Biologic Arms of Inflammatory Arthritis Clinical Trials Identifies Several Predictors of Remission, As Well As, Distinct Responder Subgroups

    Brian Tom1 and Deborah P.M. Symmons2, 1Biostatistics Unit, Medical Research Council, Cambridge, United Kingdom, 2NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

    Background/Purpose: The RA-MAP consortium is a UK flagship industry-academic partnership investigating clinical and biological predictors of disease outcome in patients with rheumatoid arthritis (RA). Methods:…
  • Abstract Number: 1027 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis Disease Activity Assessment Frequencies in Clinical Practices Do Not Support Treat-to-Target Care

    David Sikes1, James Bower2, Drew Johnson3, J. Timothy Harrington2, Rafia Khalil4, Edmund LaCour5, Michael Naarendorp6, Hillary Norton7 and Kathleen Thomas8, 1Rheumatology, Florida Medical Clinic PA, Zephyrhills, FL, 2Joiner Associates LLC, Madison, WI, 3Crescendo Bioscience, Inc., South San Francisco, CA, 4Rafia Khalil Arthritis & Rheumatology Center, PC, Port Huron, MI, 5Dothan Medical Associates PC, Dothan, AL, 6Harlem Rhematology, LLC, New York, NY, 7Rheumatology, Santa Fe Rheumatology, Santa Fe, NM, 8Community Rheumatology, Noblesville, IN

    Background/Purpose: Treat-to-Target (T2T) recommendations for rheumatoid arthritis (RA) care include standardized frequencies of disease activity (DA) assessment based on DA level. For this study, "on…
  • Abstract Number: 1691 • 2015 ACR/ARHP Annual Meeting

    The Presence of Fibromialgia May Influence the Clinimetric Evaluation of Patients with Ankylosing Spondylitis, but Has No Impact on Disease Activity Assessment

    Emilio Buschiazzo1, Natalia Zamora2, Fernando Andres Sommerfleck3, Romina Rojas Tessel4, Mariana Benegas5, Pablo Arturi6,7, Maria Elena Crespo4, Emilce Schneeberger8 and Gustavo Citera2, 1Rheumatology, Hospital Sr Del Milagro, Salta, Argentina, 2Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3Rheumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Hospital Sr Del Milagro, Salta, Argentina, 5Sanatorio Mitre, Buenos Aires, Argentina, 6Rheumatology, Instituto de Rehabilitacion Psicofisica and Fundacion Reumatologica Argentina, Buenos Aires, Argentina, 7Rheumatology, Hospital Italiano de La Plata, La Plata, Argentina, 8Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina

    Background/Purpose: Fibromyalgia (FM) can be present concomitantly in patients with Ankylosing Spondylitis (AS). It may overestimate the evaluation of disease activity, resulting in more intensive…
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