Abstracts tagged "Disease Activity"

Abstract Number: 1538 • 2016 ACR/ARHP Annual Meeting
Lower Ratings of Pain Intensity in Older Adults Lead to Underestimation of Disease Activity By Disease Activity Score 28-C-Reactive Protein (DAS28-CRP) in Patients with Rheumatoid Arthritis
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio² and Larry W. Moreland¹, ¹Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA
Background/Purpose: To investigate the influence of age on the components of the 28-joint Disease Activity Score (DAS28)-C-reactive protein (CRP) in patients with rheumatoid arthritis…
Abstract Number: 1817 • 2016 ACR/ARHP Annual Meeting
A Longitudinal Analysis of Change in Lupus Disease Activity Pattern in Hopkins Lupus Cohort Using a Multistate Markov Model Approach
Wei Fu¹ and Michelle Petri², ¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a multi-systemic inflammatory disease with extreme variability of its activity over time. We have described three main patterns: long…
Abstract Number: 2461 • 2016 ACR/ARHP Annual Meeting
Identifying Flare in Rheumatoid Arthritis: What Is the Threshold?
Elena Myasoedova¹, Cynthia S. Crowson², John M. Davis III³, Sherine E. Gabriel⁴ and Eric L. Matteson¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Dean's Office, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: The flare-assessment in RA (FLARE) questionnaire was developed for the detection of disease activity flares in patients with rheumatoid arthritis (RA) based on the…
Abstract Number: 2657 • 2016 ACR/ARHP Annual Meeting
Withdrawal of Nonsteroidal Anti-Inflammatory Drugs in Rheumatoid Arthritis Patients with Low Disease Activity
Dong Jin Go^1,2, Kichul Shin³, Han Joo Baek⁴, Seong-Wook Kang⁵, Young Mo Kang⁶, Jae-Bum Jun⁷, Yun Jong Lee⁸, Sung-Hwan Park⁹ and Yeong Wook Song^10,11, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, The Republic of, ²Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, SMG-SNU Boramae Medical Center, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea, ⁵Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Hospital, Daegu, South Korea, ⁷Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, The Republic of, ⁸Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea, ⁹Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea, ¹⁰Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, ¹¹Department of Molecular Medicine and Biopharmaceutical Sciences, BK21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, South Korea
Background/Purpose: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in relieving joint pain in rheumatoid arthritis (RA) patients, long-term use of NSAIDs can cause adverse effects.…
Abstract Number: 2831 • 2016 ACR/ARHP Annual Meeting
Associations of BAFF and Anti-BAFF Autoantibodies with Disease Activity in Oriental Systemic Lupus Erythematosus
Hwee-Siew Howe¹, Bernard Thong², Kok Ooi Kong³, Hiok-Hee Chng², Tsui Yee Lian², Faith Chia², Karine Tay², Tang Ching Lau⁴, Weng Giap Law², Ee Tzun Koh⁵ and Bernard Pui Lam Leung^6,7, ¹Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, SINGAPORE, Singapore, ²Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, ., Singapore, ³Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore, ⁴Yong Loo Lin School of Medicine,, National University of Singapore, ., Singapore, ⁵Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, ., Singapore, ⁶Physiology, National University of Singapore, ., Singapore, ⁷Rheumatology, Allergy & Immunology, Tan Tock Seng Hospital, ., Singapore
Background/Purpose: B cell activating factor (BAFF) is implicated in the pathogenesis of systemic lupus erythematosus (SLE). A previous small scale study reported that endogenous neutralizing…
Abstract Number: 3181 • 2016 ACR/ARHP Annual Meeting
The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis
Rennie L. Rhee¹, John C. Davis², Linna Ding³, Fernando Fervenza⁴, Gary S. Hoffman⁵, Cees G.M. Kallenberg⁶, Carol A. Langford⁷, W Joseph McCune⁸, Paul A. Monach⁹, Philip Seo¹⁰, Robert F. Spiera¹¹, Eugene William St.Clair¹², Ulrich Specks⁴, John H. Stone¹³ and Peter A. Merkel¹⁴, ¹Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Baxalta, Cambridge, MA, ³NIH, Bethesda, MD, ⁴Mayo Clinic, Rochester, MN, ⁵Rheumatology, Cleveland Clinic, Cleveland, OH, ⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁷Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ⁸Int Med/ Rheum, University of Michigan, Ann Arbor, MI, ⁹Rheumatology, Boston University School of Medicine, Boston, MA, ¹⁰Medicine, Johns Hopkins University, Baltimore, MD, ¹¹Hospital for Special Surgery, Cornell, New York, NY, ¹²Rheumatology and Immunology, Duke University, Durham, NC, ¹³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ¹⁴Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA
Background/Purpose: The significance of persistent hematuria or proteinuria in patients with ANCA-associated vasculitis (AAV) who are in clinical remission is still unclear. This study…
Abstract Number: 175 • 2016 ACR/ARHP Annual Meeting
Suppressor of Cytokine Function One (SOCS1) Is Elevated in Non-Classical Monocytes and Correlates with Disease Activity in Systemic Lupus Erythematosus Patients
Talha Khawar¹, Jessica Cooke², Nasim Daoud³, Vaneet Sandhu⁴, Willie Davis², Warren Peters⁵, Karina Marianne D. Torralba⁶, Michelle T. Ngo⁶, Sheila Lezcano¹, Kimberly J. Payne^7,8 and Abby Jones Weldon⁹, ¹Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ²Department of Pharmaceutical and Administrative Sciences, School of Pharmacy, Loma Linda University, Loma Linda, CA, ³Division of Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ⁴Division of Rheumatology, Loma Linda University, Loma Linda, CA, ⁵Department of Preventative Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, ⁶Rheumatology, Loma Linda University, Loma Linda, CA, ⁷Center of Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, ⁸Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA, ⁹Loma Linda University, Loma Linda, CA
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease resulting from dysregulated innate and adaptive immune components that result in an inflammatory response. Cytokines produced…
Abstract Number: 540 • 2016 ACR/ARHP Annual Meeting
The Importance of Outcome Measures in Rheumatoid Arthritis – Validity of the Routine Assessment of Patient Index Data 3 in a Real World Setting
Sergio Schwartzman¹, Keith Knapp^2,3, Gary Craig^2,3, Karen Ferguson^2,3 and Discus Analytics, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Arthritis Northwest PLLC., Spokane, WA, ³Discus Analytics LLC., Spokane, WA
The Importance of Outcome Measures in Rheumatoid Arthritis - Validity of the RAPID3 (Routine Assessment of Patient Index Data 3) in a United States “Real…
Abstract Number: 797 • 2016 ACR/ARHP Annual Meeting
Randomized Clinical Trials of Systemic Lupus Erythematosus: Evaluating Differences in the Enrolled Populations
Niti Goel^1,2, Brandon Barrett³, Ann Duncan⁴, Margaret-Beth Gallagher¹ and Marsha Mackey³, ¹Quintiles, Inc., Durham, NC, ²Duke University School of Medicine, Durham, NC, ³Quintiles, Inc., Rockville, MD, ⁴Quintiles, Inc., Reading, Berkshire, United Kingdom
Background/Purpose: Background/Purpose: Randomized controlled trials (RCTs) in SLE identify specific populations of interest for eligibility, but still vary in the recruited populations. These differences may…
Abstract Number: 1370 • 2016 ACR/ARHP Annual Meeting
Development and Validation of a Composite Disease Activity Score for Juvenile Dermatomyositis
Silvia Rosina¹, Alessandro Consolaro¹, Pieter van Dijkhuizen¹, Kiran Nistala², Nicola Ruperto¹, Clarissa Pilkington³ and Angelo Ravelli¹, ¹Rheumatology, Giannina Gaslini Institute, Genova, Italy, ²Centre for Rheumatology, University College London, London, United Kingdom, ³Paediatric Rheumatology, Great Ormond Street Hospital NHS Trust, London, United Kingdom
Background/Purpose: JDM is a multisystem vasculopathic disease that primarily affects the skin and muscles. Most tools for assessment of disease activity in JDM are lenghty,…
Abstract Number: 1545 • 2016 ACR/ARHP Annual Meeting
Vitamin D Insufficiency in Patients with Rheumatoid Arthritis and Healthy Controls and Correlation Between Vitamin D Levels and Disease Activity and Disability in RA Patients
Bhupendra Vaishnav^1,2, Bhowmik Meghnathi^1,3, Abhishek Patil¹, Sundeep Upadhyaya¹, S J Gupta¹ and Rohini Handa¹, ¹Rheumatology, Indraprastha Apollo Hospitals, New Delhi, India, ²Rheumatology, Rajiv Gandhi Superspeciality Hospital, Delhi, India, ³Rheumatology B, Groupe Hospitalier Cochin-Saint Vincent de Paul, Paris, France
Background/Purpose: Lower serum vitamin D levels have been shown to be associated with various autoimmune disorders including Rheumatoid Arthritis (RA). We undertook this study to…
Abstract Number: 1823 • 2016 ACR/ARHP Annual Meeting
African American and European American SLE Patients with Variable Disease Activity Reveal Distinct Differences in CD4+ T Cell and Monocyte Pathways
Samantha Slight-Webb¹, Rufei Lu², Krista M. Bean¹, Holden T. Maecker³, Paul J. Utz⁴, Joel M. Guthridge⁵ and Judith A. James⁶, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁴Medicine, Stanford University School of Medicine, Stanford, CA, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disorder with both genetic and environmental contributions to disease etiology. Patients with different ancestral backgrounds have different…
Abstract Number: 2466 • 2016 ACR/ARHP Annual Meeting
Remission According to RAPID3 (routine assessment of patient index data 3) in Patients with Rheumatoid Arthritis: A Cross-Sectional 3 Center Study from Routine Care
Isabel Castrejón¹, Martin J. Bergman², Kathryn Gibson^3,4, Yusuf Yazici⁵, Joel Block⁶ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, Taylor Hospital, Ridley Park, PA, ³Liverpool Hospital, Sydney, Sydney, Australia, ⁴Ingham Research Institute, Liverpool, Australia, ⁵Division of Rheumatology, NYU Hospital for Joint Diseases, New York, NY, ⁶Division of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Remission rates in patients with rheumatoid arthritis (RA) according to RAPID3 (routine assessment of patient index data) are reported at 25% in France1 and…
Abstract Number: 2675 • 2016 ACR/ARHP Annual Meeting
Essdai, Clinessdai and DAS Scoring at Diagnosis of Primary Sjogren Syndrome: Association with the Development of Hematologic and Solid Neoplasias in 1301 Patients
Soledad Retamozo^1,2, Belchin Kostov³, Guadalupe Fraile⁴, Daniel Caravia-Durán⁵, Brenda Maure⁶, Francisco Javier Rascón⁷, Mónica Zamora⁸, Arnau Casanovas⁹, Miguel Lopez-Dupla¹⁰, Mar Ripoll¹¹, Blanca Pinilla¹², Eva Fonseca¹³, Miriam Akasbi¹⁴, Gloria De la Red¹⁵, Miguel-Angel Duarte-Millán¹⁶, Patricia Fanlo Mateo¹⁷, Pablo Guisado¹⁸, Roberto Pérez-Alvarez¹⁹, Sandra Rodríguez-Rodríguez²⁰, César Morcillo²¹, Iratxe Jiménez-Heredia²², Alberto Gato²³, Jordi Gratacós¹, Isabel Sánchez-Berná¹, Manuel Ramos-Casals^24,25, Pilar Brito-Zerón^1,26 and SS Registry GEAS-SEMI, ¹Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Barcelona, Spain, ²Rheumatology Unit, Hospital Privado Centro Médico de Córdoba, Argentina, Córdoba, Argentina, ³Primary Care Research Group, IDIBAPS, ABS Les Corts, CAPSE, Barcelona, Barcelona, Spain, ⁴Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Spain, Madrid, Spain, ⁵Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, ⁶Department of Internal Medicine, Complejo Hospitalario Universitario, Vigo, Vigo, Spain, ⁷Department of Internal Medicine, Hospital Son Espases, Palma de Mallorca, Palma de Mallorca, Spain, ⁸Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Granada, Spain, ⁹Department of Internal Medicine, Hospital Parc Taulí, Sabadell, Sadabell, Spain, ¹⁰Department of Internal Medicine, Hospital Joan XXIII, Tarragona, Tarragona, Spain, ¹¹Department of Internal Medicine, Hospital Infanta Sofía, Madrid, Madrid, Spain, ¹²Department of Internal Medicine, Hospital Gregorio Marañón, Madrid, Madrid, Spain, ¹³Department of Internal Medicine, Hospital de Cabueñes, Gijón, Gijón, Spain, ¹⁴Department of Internal Medicine, Hospital Infanta Leonor, Madrid, Madrid, Spain, ¹⁵Department of Internal Medicine, Hospital Esperit Sant, Badalona, Badalona, Spain, ¹⁶Department of Internal Medicine, Hospital de Fuenlabrada, Fuenlabrada, Spain, ¹⁷Department of Internal Medicine, Hospital Virgen del Camino, Pamplona, Spain, ¹⁸Department of Internal Medicine, Complejo Hospitalario Ruber Juan Bravo, Madrid, Madrid, Spain, ¹⁹Department of Internal Medicine, Hospital Alvaro Cunqueiro, Vigo, Vigo, Spain, ²⁰Department of Internal Medicine, Hospital de Salamanca, Salamanca, Salamanca, Spain, ²¹Department of Medicine, Hospital CIMA-Sanitas, Barcelona, Barcelona, Spain, ²²Department of Internal Medicine, Hospital de Sagunto, Valencia, Valencia, Spain, ²³Department of Internal Medicine, Complejo Hospitalario Albacete, Albacete, Albacete, Spain, ²⁴Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ²⁵Department of Medicine, University of Barcelona, Barcelona, Spain., Barcelona, Spain, ²⁶Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona., Bacelona, Spain
Background/Purpose: To score systemic activity at diagnosis of primary Sjogren syndrome (pSS) using the European systemic activity indexes ESSDAI, clinESSDAI and DAS in order to…
Abstract Number: 2833 • 2016 ACR/ARHP Annual Meeting
Low Plasma Concentrations of Apolipoprotein M Correlate to Disease Activity and Endothelial Dysfunction in SLE
Helena Tydén¹, Christian Lood², Andreas Jönsen³, Birgitta Gullstrand⁴, Bjorn Dahlback⁵ and Anders A. Bengtsson³, ¹Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, ²Department of Clinical Sciences, Section of Rheumatology, Lund University and Skane University Hospital Lund Sweden, Lund University, Lund, Sweden, ³Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ⁴Department of Clinical Sciences, Division of Rheumatology, Lund University, Lund, Sweden, ⁵Department of Translational Medicine, Division of Clinical Chemistry, Lund University, Skane University Hospital Malmö, Malmö, Sweden
Background/Purpose: Human apoM is a 25kDa apolipoprotein present in 5% of HDL particles in plasma. In mouse models, apoM is antiatherogenic and vasculoprotective and…

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