Abstracts tagged "Disease Activity"

Abstract Number: 529 • 2016 ACR/ARHP Annual Meeting
The Relationship Between Promis and CDAI Scores, Disease Duration, Age and Gender in Patients with Rheumatoid Arthritis
Alicia Lieberman¹, Judith Baumhauer², Chris Dasilva² and Allen P. Anandarajah³, ¹Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²Orthopedic surgery, University of Rochester Medical Center, Rochester, NY, ³Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY
Background/Purpose: PROMIS (Patient-Reported Outcomes Measurement Information System) is a self-reported and parent-reported measure of global, physical, mental, and social health for the general population…
Abstract Number: 794 • 2016 ACR/ARHP Annual Meeting
Development and Initial Validation of a Novel Lupus Disease Activity Index to Account for Glucocorticoids: Sledai-2K Glucocorticoids Index (SGI)
Zahi Touma¹, Dafna D Gladman², Jiandong Su³ and Murray Urowitz¹, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: It is challenging to describe disease activity in SLE in the context of multiple levels of glucocorticoids (GC) treatment. We aim to develop and…
Abstract Number: 1367 • 2016 ACR/ARHP Annual Meeting
Long-Term Outcomes and Their Predictors in Patients with Juvenile Idiopathic Inflammatory Myopathies of Adult Age: A Referral Population Study
Sam Serafi¹, Vladislav Tsaltskan², Anna Yakovleva³, Heidi Sami¹, Frederick W. Miller⁴, Rodolfo Curiel¹, Olcay Y. Jones^1,5 and Lisa G. Rider^1,4, ¹Rheumatology, George Washington University, Washington, DC, ²Internal Medicine, George Washington University, Washington, DC, ³Department of Microbiology, Immunology, and Tropical Medicine., George Washington University, Washington, DC, ⁴Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD, ⁵Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD
Background/Purpose: To investigate the long-term outcomes and prognostic factors for pts with juvenile-onset idiopathic inflammatory myopathies (JIIM) who are currently adults. Methods: Adults with JIIM…
Abstract Number: 1538 • 2016 ACR/ARHP Annual Meeting
Lower Ratings of Pain Intensity in Older Adults Lead to Underestimation of Disease Activity By Disease Activity Score 28-C-Reactive Protein (DAS28-CRP) in Patients with Rheumatoid Arthritis
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio² and Larry W. Moreland¹, ¹Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology, University of Pittsburgh, School of Public Health, Pittsburgh, PA
Background/Purpose: To investigate the influence of age on the components of the 28-joint Disease Activity Score (DAS28)-C-reactive protein (CRP) in patients with rheumatoid arthritis…
Abstract Number: 1817 • 2016 ACR/ARHP Annual Meeting
A Longitudinal Analysis of Change in Lupus Disease Activity Pattern in Hopkins Lupus Cohort Using a Multistate Markov Model Approach
Wei Fu¹ and Michelle Petri², ¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a multi-systemic inflammatory disease with extreme variability of its activity over time. We have described three main patterns: long…
Abstract Number: 2466 • 2016 ACR/ARHP Annual Meeting
Remission According to RAPID3 (routine assessment of patient index data 3) in Patients with Rheumatoid Arthritis: A Cross-Sectional 3 Center Study from Routine Care
Isabel Castrejón¹, Martin J. Bergman², Kathryn Gibson^3,4, Yusuf Yazici⁵, Joel Block⁶ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, Taylor Hospital, Ridley Park, PA, ³Liverpool Hospital, Sydney, Sydney, Australia, ⁴Ingham Research Institute, Liverpool, Australia, ⁵Division of Rheumatology, NYU Hospital for Joint Diseases, New York, NY, ⁶Division of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Remission rates in patients with rheumatoid arthritis (RA) according to RAPID3 (routine assessment of patient index data) are reported at 25% in France1 and…
Abstract Number: 2675 • 2016 ACR/ARHP Annual Meeting
Essdai, Clinessdai and DAS Scoring at Diagnosis of Primary Sjogren Syndrome: Association with the Development of Hematologic and Solid Neoplasias in 1301 Patients
Soledad Retamozo^1,2, Belchin Kostov³, Guadalupe Fraile⁴, Daniel Caravia-Durán⁵, Brenda Maure⁶, Francisco Javier Rascón⁷, Mónica Zamora⁸, Arnau Casanovas⁹, Miguel Lopez-Dupla¹⁰, Mar Ripoll¹¹, Blanca Pinilla¹², Eva Fonseca¹³, Miriam Akasbi¹⁴, Gloria De la Red¹⁵, Miguel-Angel Duarte-Millán¹⁶, Patricia Fanlo Mateo¹⁷, Pablo Guisado¹⁸, Roberto Pérez-Alvarez¹⁹, Sandra Rodríguez-Rodríguez²⁰, César Morcillo²¹, Iratxe Jiménez-Heredia²², Alberto Gato²³, Jordi Gratacós¹, Isabel Sánchez-Berná¹, Manuel Ramos-Casals^24,25, Pilar Brito-Zerón^1,26 and SS Registry GEAS-SEMI, ¹Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Barcelona, Spain, ²Rheumatology Unit, Hospital Privado Centro Médico de Córdoba, Argentina, Córdoba, Argentina, ³Primary Care Research Group, IDIBAPS, ABS Les Corts, CAPSE, Barcelona, Barcelona, Spain, ⁴Department of Internal Medicine, Hospital Ramón y Cajal, Madrid, Spain, Madrid, Spain, ⁵Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, ⁶Department of Internal Medicine, Complejo Hospitalario Universitario, Vigo, Vigo, Spain, ⁷Department of Internal Medicine, Hospital Son Espases, Palma de Mallorca, Palma de Mallorca, Spain, ⁸Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Granada, Spain, ⁹Department of Internal Medicine, Hospital Parc Taulí, Sabadell, Sadabell, Spain, ¹⁰Department of Internal Medicine, Hospital Joan XXIII, Tarragona, Tarragona, Spain, ¹¹Department of Internal Medicine, Hospital Infanta Sofía, Madrid, Madrid, Spain, ¹²Department of Internal Medicine, Hospital Gregorio Marañón, Madrid, Madrid, Spain, ¹³Department of Internal Medicine, Hospital de Cabueñes, Gijón, Gijón, Spain, ¹⁴Department of Internal Medicine, Hospital Infanta Leonor, Madrid, Madrid, Spain, ¹⁵Department of Internal Medicine, Hospital Esperit Sant, Badalona, Badalona, Spain, ¹⁶Department of Internal Medicine, Hospital de Fuenlabrada, Fuenlabrada, Spain, ¹⁷Department of Internal Medicine, Hospital Virgen del Camino, Pamplona, Spain, ¹⁸Department of Internal Medicine, Complejo Hospitalario Ruber Juan Bravo, Madrid, Madrid, Spain, ¹⁹Department of Internal Medicine, Hospital Alvaro Cunqueiro, Vigo, Vigo, Spain, ²⁰Department of Internal Medicine, Hospital de Salamanca, Salamanca, Salamanca, Spain, ²¹Department of Medicine, Hospital CIMA-Sanitas, Barcelona, Barcelona, Spain, ²²Department of Internal Medicine, Hospital de Sagunto, Valencia, Valencia, Spain, ²³Department of Internal Medicine, Complejo Hospitalario Albacete, Albacete, Albacete, Spain, ²⁴Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain, ²⁵Department of Medicine, University of Barcelona, Barcelona, Spain., Barcelona, Spain, ²⁶Autoimmune Diseases Unit, Department of Medicine, Hospital CIMA- Sanitas, Barcelona., Bacelona, Spain
Background/Purpose: To score systemic activity at diagnosis of primary Sjogren syndrome (pSS) using the European systemic activity indexes ESSDAI, clinESSDAI and DAS in order to…
Abstract Number: 2833 • 2016 ACR/ARHP Annual Meeting
Low Plasma Concentrations of Apolipoprotein M Correlate to Disease Activity and Endothelial Dysfunction in SLE
Helena Tydén¹, Christian Lood², Andreas Jönsen³, Birgitta Gullstrand⁴, Bjorn Dahlback⁵ and Anders A. Bengtsson³, ¹Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, ²Department of Clinical Sciences, Section of Rheumatology, Lund University and Skane University Hospital Lund Sweden, Lund University, Lund, Sweden, ³Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ⁴Department of Clinical Sciences, Division of Rheumatology, Lund University, Lund, Sweden, ⁵Department of Translational Medicine, Division of Clinical Chemistry, Lund University, Skane University Hospital Malmö, Malmö, Sweden
Background/Purpose: Human apoM is a 25kDa apolipoprotein present in 5% of HDL particles in plasma. In mouse models, apoM is antiatherogenic and vasculoprotective and…
Abstract Number: 3186 • 2016 ACR/ARHP Annual Meeting
Determinants of Patient-Physician Discordance in Global Assessment in Psoriatic Arthritis and Levels of Discordance According to Disease Activity: A Multicenter European Study
Carole Desthieux¹, Benjamin Granger², Andra Rodica Balanescu³, P Balint⁴, Jürgen Braun⁵, Juan Canete⁶, Turid Heiberg⁷, Philip S. Helliwell⁸, Umut Kalyoncu⁹, Tore K Kvien¹⁰, Uta Kiltz⁵, Dora Niedermayer¹¹, Kati Otsa¹², Rossana Scrivo¹³, Josef Smolen¹⁴, Tanja A. Stamm¹⁵, Douglas J. Veale¹⁶, Kurt de Vlam¹⁷, Maarten de Wit¹⁸ and Laure Gossec¹, ¹Rheumatology, Pitié Salpêtrière Hospital, Paris, France, ²Biostatistics, Pitié Salpêtrière Hospital, Paris, France, ³Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁴Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, ⁵Rheumazentrum Ruhrgebiet, Herne, Germany, ⁶Rheumatology, Hospital Clínic and IDIBAPS, Barcelona, Spain, ⁷Oslo University Hospital, Oslo, Norway, ⁸NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁹Hacettepe University, Ankara, Turkey, ¹⁰Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ¹¹PsAID taskforce, EULAR, Zurich, Switzerland, ¹²Rheumatology, Tallinn Central Hospital, Tallinn, EE, ¹³Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, ¹⁴Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ¹⁵Internal Medicine III, Vienna Medical University, Vienna, Austria, ¹⁶Consultant Rheumatologist, Centre for Arthritis and Rheumatic Disease, St. Vincent’s University Hospital and University College Dublin, Dublin 4, Ireland, ¹⁷Katholieke Universiteit Leuven, Leuven, Belgium, ¹⁸Medical Humanities, VU Medical Centre, Amsterdam, Netherlands
Background/Purpose: In the management of chronic diseases, recommendations insist on the need to work in partnership with the patient. Patient-physician discordance in global assessment of…
Abstract Number: 175 • 2016 ACR/ARHP Annual Meeting
Suppressor of Cytokine Function One (SOCS1) Is Elevated in Non-Classical Monocytes and Correlates with Disease Activity in Systemic Lupus Erythematosus Patients
Talha Khawar¹, Jessica Cooke², Nasim Daoud³, Vaneet Sandhu⁴, Willie Davis², Warren Peters⁵, Karina Marianne D. Torralba⁶, Michelle T. Ngo⁶, Sheila Lezcano¹, Kimberly J. Payne^7,8 and Abby Jones Weldon⁹, ¹Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ²Department of Pharmaceutical and Administrative Sciences, School of Pharmacy, Loma Linda University, Loma Linda, CA, ³Division of Rheumatology, Loma Linda University Medical Center, Loma Linda, CA, ⁴Division of Rheumatology, Loma Linda University, Loma Linda, CA, ⁵Department of Preventative Medicine, School of Medicine, Loma Linda University, Loma Linda, CA, ⁶Rheumatology, Loma Linda University, Loma Linda, CA, ⁷Center of Health Disparities and Molecular Medicine, Loma Linda University, Loma Linda, CA, ⁸Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA, ⁹Loma Linda University, Loma Linda, CA
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease resulting from dysregulated innate and adaptive immune components that result in an inflammatory response. Cytokines produced…
Abstract Number: 540 • 2016 ACR/ARHP Annual Meeting
The Importance of Outcome Measures in Rheumatoid Arthritis – Validity of the Routine Assessment of Patient Index Data 3 in a Real World Setting
Sergio Schwartzman¹, Keith Knapp^2,3, Gary Craig^2,3, Karen Ferguson^2,3 and Discus Analytics, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Arthritis Northwest PLLC., Spokane, WA, ³Discus Analytics LLC., Spokane, WA
The Importance of Outcome Measures in Rheumatoid Arthritis - Validity of the RAPID3 (Routine Assessment of Patient Index Data 3) in a United States “Real…
Abstract Number: 797 • 2016 ACR/ARHP Annual Meeting
Randomized Clinical Trials of Systemic Lupus Erythematosus: Evaluating Differences in the Enrolled Populations
Niti Goel^1,2, Brandon Barrett³, Ann Duncan⁴, Margaret-Beth Gallagher¹ and Marsha Mackey³, ¹Quintiles, Inc., Durham, NC, ²Duke University School of Medicine, Durham, NC, ³Quintiles, Inc., Rockville, MD, ⁴Quintiles, Inc., Reading, Berkshire, United Kingdom
Background/Purpose: Background/Purpose: Randomized controlled trials (RCTs) in SLE identify specific populations of interest for eligibility, but still vary in the recruited populations. These differences may…
Abstract Number: 1370 • 2016 ACR/ARHP Annual Meeting
Development and Validation of a Composite Disease Activity Score for Juvenile Dermatomyositis
Silvia Rosina¹, Alessandro Consolaro¹, Pieter van Dijkhuizen¹, Kiran Nistala², Nicola Ruperto¹, Clarissa Pilkington³ and Angelo Ravelli¹, ¹Rheumatology, Giannina Gaslini Institute, Genova, Italy, ²Centre for Rheumatology, University College London, London, United Kingdom, ³Paediatric Rheumatology, Great Ormond Street Hospital NHS Trust, London, United Kingdom
Background/Purpose: JDM is a multisystem vasculopathic disease that primarily affects the skin and muscles. Most tools for assessment of disease activity in JDM are lenghty,…
Abstract Number: 1545 • 2016 ACR/ARHP Annual Meeting
Vitamin D Insufficiency in Patients with Rheumatoid Arthritis and Healthy Controls and Correlation Between Vitamin D Levels and Disease Activity and Disability in RA Patients
Bhupendra Vaishnav^1,2, Bhowmik Meghnathi^1,3, Abhishek Patil¹, Sundeep Upadhyaya¹, S J Gupta¹ and Rohini Handa¹, ¹Rheumatology, Indraprastha Apollo Hospitals, New Delhi, India, ²Rheumatology, Rajiv Gandhi Superspeciality Hospital, Delhi, India, ³Rheumatology B, Groupe Hospitalier Cochin-Saint Vincent de Paul, Paris, France
Background/Purpose: Lower serum vitamin D levels have been shown to be associated with various autoimmune disorders including Rheumatoid Arthritis (RA). We undertook this study to…
Abstract Number: 1823 • 2016 ACR/ARHP Annual Meeting
African American and European American SLE Patients with Variable Disease Activity Reveal Distinct Differences in CD4+ T Cell and Monocyte Pathways
Samantha Slight-Webb¹, Rufei Lu², Krista M. Bean¹, Holden T. Maecker³, Paul J. Utz⁴, Joel M. Guthridge⁵ and Judith A. James⁶, ¹Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁴Medicine, Stanford University School of Medicine, Stanford, CA, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disorder with both genetic and environmental contributions to disease etiology. Patients with different ancestral backgrounds have different…

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