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Abstracts tagged "Disease Activity"

  • Abstract Number: 1548 • ACR Convergence 2020

    Blood Pressure, BMI and Sex Affect Optical Spectral Transmission Imaging Measurements of the Hands

    Annelies Blanken1, Conny van der Laken2 and Mike Nurmohamed3, 1Amsterdam Rheumatology and immunology Center location Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center, location Amsterdam UMC, VU medical center, Amsterdam, Netherlands, 3Amsterdam Rheumatology and immunology Center, location Reade and Amsterdam UMC, VU medical center, Amsterdam, Netherlands

    Background/Purpose: Optical spectral transmission imaging (OST) is a new imaging method designed to measure inflammation in the hands of rheumatoid arthritis (RA) patients. The device…
  • Abstract Number: 1732 • ACR Convergence 2020

    Machine Learning Coupled with Patient Reported Outcome Data to Classify & Predict RA Disease Activity

    Jeffrey R Curtis1, Fenglong Xie2, Shelly Kafka3 and Shawn Black3, 1Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Janssen Scientific Affairs, LLC, Horsham, PA

    Background/Purpose: Patient reported outcome (PRO) data have assumed increasing importance in the care of rheumatoid arthritis (RA) patients. However, physician-derived disease activity measures such as…
  • Abstract Number: 1851 • ACR Convergence 2020

    Different Disease Activity Trajectories in Early Axial Spondyloarthritis Lead to Significantly Different Long-term Outcomes : A Cluster-based Analysis of the DESIR Cohort

    Benattar Leslie1, Anna Molto2, Laure Gossec3 and Resche Rigon Matthieu4, 1Cochin Hospital, Paris, Paris, Ile-de-France, France, 2Rheumatology Department, Cochin Hospital, APHP, Paris, France, Paris, France, 3Sorbonne University, INSERM; Pitié-Salpêtrière Hospital, Paris, Ile-de-France, France, 4INSERM (UFR 1153), Saint Louis Hospital, Paris, Paris, France

    Background/Purpose:  AxSpA is a heterogeneous disease, leading to different treatment and follow-up modalities depending on the presentation, along with other elements (socio-economic, gender, etc..). In a…
  • Abstract Number: 0003 • ACR Convergence 2020

    Assessing Cytokine Profiles and COVID Serology in Patients on Immunosuppression to Guide Care Recommendations

    Quinn Pritchett1, Rebecca Overbury1, Dorota Lebiedz-Odrobina1, Julie Thomas1, Tawnie Braaten2, Stacey Clardy1, Marc Elgort3, Emily Spivak1, Patricia Slev3, Lisa Peterson3 and Tracy Frech4, 1University of Utah, Salt Lake City, UT, 2University of Utah, Salt Lake City, 3ARUP, Salt Lake City, UT, 4University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT

    Background/Purpose: The COVID-19 pandemic is especially terrifying for patients on immunosuppression for autoimmune disease. With the exception of social isolation, experts do not have clear…
  • Abstract Number: 0249 • ACR Convergence 2020

    Validation of the SIMPLE Index for Disease Activity of Systemic Lupus Erythematosus in Chinese Patients

    Chi Chiu Mok1, Ling Yin Ho1, Kar Li Chan2 and Meenakshi Jolly3, 1Tuen Mun Hospital, Hong Kong, China (People's Republic), 2Tuen Mun Hospital, Hong Kong, Hong Kong, 3Rush University, Chicago, IL

    Background/Purpose: The SIMPLE (SIMple Disease Assessment for People with Lupus Erythematosus) index is a composite numeric tool that captures disease activity from patients’ self-assessment with…
  • Abstract Number: 0361 • ACR Convergence 2020

    Response to Treatment with Ixekizumab in Patients with Active Non-Radiographic Axial Spondyloarthritis Based on HLA-B27 Status and Disease Duration

    Victoria Navarro-Compán1, Jose Maldonado-Cocco2, Proton Rahman3, Andris Kronbergs4, David Sandoval4, So Young Park4, Theresa Hunter4 and Marina Magrey5, 1Hospital Universitario La Paz IdiPaz, Madrid, Pais Vasco, Spain, 2University of Buenos Aires School of Medicine, Buenos Aires, Argentina, 3Memorial University of Newfoundland, Department of Medicine, St John's, Canada, 4Eli Lilly and Company, Indianapolis, 5Case Western Reserve University School of Medicine, Cleveland, OH

    Background/Purpose: In this analysis, we evaluate the efficacy of ixekizumab at week 16 in patients with non-radiographic axial spondyloarthritis (nr-axSpA) with or without baseline HLA-B27…
  • Abstract Number: 0751 • ACR Convergence 2020

    Serum Interferon-Alpha Levels Could Help Identify a Subgroup of Rheumatoid Arthritis with Poorer Physical Function and Higher Physician Global Assessment

    Yong Gil Hwang1, Lei Zhu2, Dongwen Wu2 and Larry Moreland3, 1University of Pittsburgh Physicians, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Colorado, Colorado

    Background/Purpose: Our objective was to identify the clinical significance of serum interferon-alpha levels in patients with established rheumatoid arthritis (RA).Methods: Serum samples and clinical data…
  • Abstract Number: 0878 • ACR Convergence 2020

    Absolute Lymphocyte Count Is Negatively Correlated with Atherosclerotic Cardiovascular Disease Risk Score and Red Cell Distribution Width in Psoriatic Arthritis and Increases with TNF-Inhibitor Therapy

    Angela Gupta1, Sofi Damjanovska2, Alyssa Lange3, Brigid Wilson4, Taissa Bej4, Maya Mattar5, David Zidar6 and Donald Anthony7, 1(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 2(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 3Case Western Reserve University, Cleveland, 4Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 5Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 6Case Western Reserve University/Cleveland VA Medical Center, Cleveland, 7Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH

    Background/Purpose: Absolute lymphocyte count (ALC) is a parameter that represents the number of lymphocytes (B, T, and NK cells) in the blood, and lymphopenia often…
  • Abstract Number: 1152 • ACR Convergence 2020

    IL-18: A Biomarker That Reflects Disease Activity, Could It Be the Next Disease Activity Measure in Systemic Juvenile Idiopathic Arthritis?

    Shima Yasin1, Thuy Do2, Sanjeev Dhakal2, Elizabeth Baker2, Alexei Grom3 and Grant Schulert4, 1Cincinnati Children's Hospital Medical Center, Liberty twp, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnati, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with prominent innate immune activity. Disease presentation and flares could largely mimic infections with fever…
  • Abstract Number: 1291 • ACR Convergence 2020

    Depressed Symptomatology Persists over Time in the Majority of Systemic Lupus Erythematosus Patients and Is Independent of Disease Activity

    Sara Kellahan1, Xinliang Huang1, Daphne Lew2, Hong Xian3, Seth Eisen1 and Alfred Kim4, 1Division of Rheumatology, Washington University in St. Louis School of Medicine, St. Louis, 2Division of Biostatistics, Washington University in St. Louis School of Medicine, St. Louis, 3Department of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, St. Louis, 4Washington University School of Medicine, St. Louis, MO

    Background/Purpose: Depression is a prevalent (24-30%) and significant comorbidity in patients with systemic lupus erythematosus (SLE) (1).  As the American College of Rheumatology (ACR) classifies…
  • Abstract Number: 1549 • ACR Convergence 2020

    Joint Damage and Malalignment Determine Articular Tenderness More Than Inflammation in Rheumatoid Arthritis, Psoriatic Arthritis or Osteoarthritis in Established Disease

    Mihaela Popescu1, Victoria Schimpl2, Gabriela Supp3, Martina Durechova3, Paul Studenic3, Michael Zauner3, Josef Smolen3, Daniel Aletaha4, Peter Mandl3 and Irina Gessl3, 1Hôpital Maisonneuve-Rosemont, Montreal, Canada, 2Medical University of Vienna, Vienna, Austria, 3Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, 4Division of Rheumatology, Department of Medicine III, Medical University of Vienna,, Vienna, Austria

    Background/Purpose: To determine whether clinical tenderness can be considered a sign of inflammatory joint activity in patients with rheumatoid arthritis (RA), osteoarthritis (OA) or psoriatic…
  • Abstract Number: 1738 • ACR Convergence 2020

    Promote Treat-to-Target for RA via Empowering Patients: A Cohort Study from China by Smart System of Disease Management (SSDM)

    Jing Yang1, Rong Mu2, Chun Li3, Bin Wu4, Hongzhi Wang5, Wenqiang Fan6, Jinmei Zou7, Yu Zhang1, Fen Li8, Xiaofeng Rong9, Jianhong Wu10, Yong Wang11, Shengguang Li12, Yi Zhao13, Xiaoqiang Hou14, Hui Xiao15, Yuhua Jia16, Bing Wu16, Miaomiao Song16, Fei Xiao16 and Zhanguo Li17, 1Department of Rheumatology, Mianyang Central Hospital, Mianyang, China (People's Republic), 2People's Hospital, Beijing University Medical School, Beijing, Beijing, China (People's Republic), 3People's Hospital, Beijing University Medical School, beijing, China (People's Republic), 4Chongqing Hospital of Traditional Chinese Medicine, chongqing, China (People's Republic), 5The First Hospital of Jiaxing, Jiaxing, China (People's Republic), 6Central Hospital of XinXiang, Xinxiang, China (People's Republic), 7Department of Rheumatology, Mianyang Central Hospital, Mianyang, Sichuan, China (People's Republic), 8The Second Xiangya Hospital of Central South University, hunan, China (People's Republic), 9The First Affiliated Hospital of Chongqing Medical University, chongqing, China (People's Republic), 10Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 11The first Hospital Affiliated to AMU (Southernwest Hospital), chongqing, China (People's Republic), 12Peking University International Hospital, Beijing, China (People's Republic), 13Xuanwu Hospital, Capital Medical University, Beijing, China, Beijing, China (People's Republic), 14Yichang Central People's Hospital, Beijing, China (People's Republic), 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 16Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 17Peking University People’s Hospital, Xicheng, Beijing, China (People's Republic)

    Background/Purpose: Treat-to-Target (T2T) strategy are critical for the treatment of RA, but Chinese rheumatologists can hardly provide patients with a complete assessment in the clinic…
  • Abstract Number: 1853 • ACR Convergence 2020

    Association of Gut Dysbiosis with Radiographic and Enthesis Involvement, Disease Activity and Duration in Axial Spondyloarthritis. Data from CASTRO Registry

    Ignacio Gómez-García1, Isabel Moreno-Indias2, María-Carmen Abalos-Aguilera1, Clementina Lopez-Medina3, Lourdes Ladehesa-Pineda4, Concepción Aranda-Valera4, Carolina Gutierrez-Repiso2, Yolanda Jimenez-Gomez5, Nuria Barbarroja1, Chary Lopez-Pedrera1, Francisco-Jose Tinahones2, Eduardo Collantes-Estévez4, Alejandro Escudero-Contreras4 and Patricia Ruiz-Limon6, 1Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 2Biomedical Research Institute of Malaga (IBIMA)/ Endocrinology and Nutrition Department, Virgen de la Victoria Hospital, Malaga, Spain/ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain, Malaga, Spain, 3Rheumatology Department, Cochin Hospital, Paris, Paris, France, 4Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 5Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 6Biomedical Research Institute of Málaga (IBIMA)/ Endocrinology and Nutrition Department, Virgen de la Victoria Hospital, Malaga, Spain, Malaga, Spain

    Background/Purpose: The etiopathogenesis of axial spondyloarthritis (AxSpA) is multifactorial. The possible role of alteration in gut microbiome (dysbiosis) has been recently suggested. However, the association…
  • Abstract Number: 0022 • ACR Convergence 2020

    Association Between Changes in Pain Sensitization and Changes in Disease Activity After 12 Weeks of Disease Modifying Anti-Rheumatic Drug Therapy in Rheumatoid Arthritis

    Andrew Heisler1, Jing Song2, Lutfiyya Muhammad3, Alyssa Wohlfahrt4, Wendy Marder5, Marcy Bolster6, Clifton Bingham III7, Daniel Clauw8, Dorothy Dunlop9, Tuhina Neogi10 and Yvonne Lee3, 1Northwestern University Feinberg School of Medicine, Oak Park, IL, 2Northwestern University, Chicago, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Brigham and Womans Hospital, Boston, MA, 5University of Michigan, Ann Arbor, MI, 6Massachusetts General Hospital, Concord, MA, 7Johns Hopkins University, Baltimore, MD, 8Michigan Medicine, Ann Arbor, MI, 9Northwestern University, New Haven, CT, 10Boston University School of Medicine, Boston, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have abnormalities in central nervous system regulation of pain, leading to enhanced pain sensitivity at joint sites (peripheral sensitization)…
  • Abstract Number: 0254 • ACR Convergence 2020

    LLDAS (Low Lupus Disease Activity State) and Remission Prevent Damage Accrual in Systemic Lupus Erythematosus (SLE) Patients in a Primarily Mestizo Cohort

    Manuel Ugarte-Gil1, Rocío V. Gamboa-Cárdenas2, Cristina Reátegui-Sokolova3, Victor Pimentel-Quiroz4, Mariela Medina2, Claudia Elera-Fitzcarrald4, Francisco Zevallos2, César A. Pastor-Asurza5, Jennifer Lofland6, Federico Zazzetti7, Chetan Karyekar8, Graciela Alarcón9 and Risto Perich-Campos5, 1Department of Rheumatology, Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Científica del Sur, Lima, Peru, 2Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 3Hospital Guillermo Almenara Irigoyen; Universidad San Ignacio de Loyola, Lima, Peru, 4Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Científica del Sur, Lima, Peru, 5Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Nacional Mayor de San Marcos, Lima, Peru, 6Global Commercial Strategic Organisation, Johnson and Johnson, Horsham, PA, 7Janssen Scientific Affairs, LLC, Buenos Aires, Argentina, 8Janssen Global Services, LLC, Horsham, PA, 9Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham; Department of Medicine, School of Medicine; Universidad Peruana Cayetano, Heredia, Alabama

    Background/Purpose: LLDAS and remission have been proposed as treatment goals for SLE patients. However, their impact on damage prevention in patients from Latin America has…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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