Abstracts tagged "Disease Activity"

Abstract Number: 1722 • ACR Convergence 2021
Risk of Pre-eclampsia and Impact of Disease Activity and Anti-rheumatic Treatment in Women with Rheumatoid Arthritis, Axial Spondylarthritis, and Psoriatic Arthritis – A Collaborative Matched Cohort Study from Sweden and Denmark
Anne Emilie Secher¹, Karin Hellgren², Bente Glintborg³, Ane Rom⁴, Merete Hetland⁵ and Fredrik Granath², ¹COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Frederiksberg, Denmark, ²Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden, ³COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ⁴The Juliane Marie Centre, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁵DANBIO and COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark
Background/Purpose: Pre-eclampsia is a pregnancy-related syndrome with potentially fatal outcomes. In RA, high disease activity has been associated to adverse pregnancy outcomes such as preterm…
Abstract Number: 1912 • ACR Convergence 2021
Meteorological Variables Have Different Effect on Core Measures of Disease Activity in Patients with Rheumatoid Arthritis
Peter Mandl¹, Paul Studenic², Farideh Alasti¹, Rainer Kaltenberger³, Andreas Kerschbaumer¹, Thomas Krennert³, Josef Smolen¹ and Daniel Aletaha⁴, ¹Medical University of Vienna, Vienna, Austria, ²Karolinska Institute; & Medical University of Vienna, Stockholm, Sweden, ³Central Institute for Meteorology and Geodynamics, Vienna, Austria, ⁴Medical University Vienna, Vienna, Austria
Background/Purpose: The notion that weather conditions may influence the symptoms and course of rheumatic and musculoskeletal diseases goes back to ancient times. We aimed to…
Abstract Number: 0042 • ACR Convergence 2020
Racial and Ethnic Differences in a Multiple Biochemical Measure of Rheumatoid Arthritis Disease Activity
Rahaf Baker¹, Jonathan Graf², Laura Trupin², Sarah Goglin³, Patricia Katz⁴, Jennifer Barton⁵, Jean Liew⁶ and Katherine Wysham⁷, ¹Highland Hospital Internal Medicine, Oakland, CA, ²UCSF, San Francisco, CA, ³University of California San Francisco, Burlingame, CA, ⁴University of California, San Francisco, Novato, CA, ⁵VAPORHCS/OHSU, Portland, OR, ⁶University of Washington, Seattle, WA, ⁷VA Puget Sound/University of Washington, Seattle, WA
Background/Purpose: Although management of RA has improved greatly over the past two decades with the advent of novel therapeutics, racial/ethnic and socioeconomic disparities persist. Traditional…
Abstract Number: 0266 • ACR Convergence 2020
The Correlation Between Pregnancy, Disease Activity and Adverse Pregnancy Outcomesin Patients with Systemic Lupus Erythematosus
Cigdem Cetin¹, Tugba Sarac Sivrikoz¹, Muge Ates Tıkız¹, Ege Sinan Torun¹, Sibel Zarali¹, Yasemin Yalcinkaya¹, Ahmet Gül¹, Murat İnanç¹, Mahdume Lale Öcal², İbrahim Kalelioğlu¹ and Bahar Artim Esen¹, ¹İstanbul Faculty of Medicine, İstanbul, Turkey, ²Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey
Background/Purpose: Patients with systemic lupus erythematosus (SLE) can present with acute disease flares/exacerbations during pregnancy and postpartum period1. These flares can cause adverse pregnancy outcomes…
Abstract Number: 0428 • ACR Convergence 2020
Enrichment of Clinical Trial Recruitment Using Advanced Molecular Imaging in Takayasu’s Arteritis
Kaitlin Quinn¹, Mark Ahlman², Emily Rose³, Peter Merkel⁴ and Peter C. Grayson⁵, ¹Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, ²National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD, ³Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴University of Pennsylvania, Philadelphia, PA, ⁵Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD
Background/Purpose: Definitions of disease activity are not standardized in Takayasu’s arteritis (TAK), which can lead to difficulty in determining whether a patient should be enrolled…
Abstract Number: 0795 • ACR Convergence 2020
Minimum Clinically Important Improvement in Patients with Rheumatoid Arthritis Associates with Gut Microbiome
Vinod Gupta¹, Kevin Cunningham², Benjamin Hur¹, John Davis¹ and Jaeyun Sung¹, ¹Mayo Clinic, Rochester, MN, ²University of Minnesota, Minneapolis, MN
Background/Purpose: Within the past decade, there have been several major discoveries in cross-sectional gut microbiome studies suggesting that dysbiosis of the gut microbiota is a…
Abstract Number: 0900 • ACR Convergence 2020
Achievement of Low Disease Activity According to BASDAI with Ixekizumab in Patients with Axial Spondyloarthritis: 16-Week Results from the COAST Trials
Denis Poddubnyy¹, Xavier Juanola², Clément Prati³, Hagen Russ⁴, Yves Schymura⁴, Soyi Liu-Leage⁵, Mani Haschemi Nassab⁴ and Jean Dudler⁶, ¹Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Rheumatology Service, University Hospital Bellvitge, IDIBELL, Barcelona, Spain, Barcelona, Spain, ³Service de Rhumatologie, Hôpital Jean-Minjoz , Besançon, France, Besançon, France, ⁴Eli Lilly and Company, Indianapolis, Indiana, USA, Indianapolis, IN, ⁵Eli Lilly and Company, Indianapolis, IN, ⁶Department of Rheumatology, HFR Fribourg - Hospital Cantonal, Fribourg, Switzerland, Fribourg, Switzerland
Background/Purpose: The efficacy of ixekizumab (IXE), a selective interleukin-17A antagonist, was assessed in patients (pts) with axial SpA (axSpA) in three Phase 3, randomized, double-blind,…
Abstract Number: 1180 • ACR Convergence 2020
External Validation of a Multi-biomarker-Based Cardiovascular Disease Risk Prediction Score for Rheumatoid Arthritis Patients
Jeffrey R Curtis¹, Eric Sasso², Elena Hitraya², Cheryl Chin³, Richard Bamford³, Rotem Ben-Shachar³, Alexander Gutin³, Darl Flake³, Brent Mabey³ and Jerry Lanchbury³, ¹Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Myriad Autoimmune, South San Francisco, CA, ³Myriad Genetics, Inc., Salt Lake City, UT
Background/Purpose: A novel score for predicting 3-year risk for CVD events in RA patients combines age, four traditional CVD risk factors (diabetes, hypertension, smoking, history…
Abstract Number: 1308 • ACR Convergence 2020
The Presence of Spondyloarthritis Is Associated with Higher Clinical Disease Activity in Patients with Early Crohn’s Disease: Results of a Prospective Cohort Study
Valeria Rios Rodriguez¹, Mikhail Protopopov¹, Fabian Proft¹, Susanne Lüders¹, Judith Rademacher¹, Hildrun Haibel¹, Maryna Verba¹, Joachim Sieper¹, Elena Sonnenberg¹, Lea Isabell Kredel¹, Michael Schumann¹, Britta Siegmund¹ and Denis Poddubnyy², ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Inflammatory bowel disease (IBD) and specifically Crohn’s disease (CD) is known to be associated with spondyloarthritis (SpA) (1). However, only little is known about…
Abstract Number: 1603 • ACR Convergence 2020
P4 Index Correlates with RAPID3 and Disease-Specific Indices in Rheumatoid Arthritis (RA) and Axial Spondyloarthritis (axSpA)
Abhijeet Danve¹, Betty Hsiao² and Phillip Zhang³, ¹Yale University, Rocky Hill, CT, ²Yale Rheumatology, New Haven, ³Yale University, New Haven, CT
Background/Purpose: RAPID3 scores correlate well with disease-specific indices, including the Clinical Disease Activity Index (CDAI) in RA and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)…
Abstract Number: 1770 • ACR Convergence 2020
Lupus Low Disease Activity State Protects Against Pre-Term Birth
Michelle Petri¹, Jessica Li² and Daniel Goldman³, ¹Johns Hopkins University School of Medicine, Baltimore, ²Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University School of Medicine, Timonium, MD
Background/Purpose: Lupus low disease activity state (LLDAS) (Ann Rheum Dis. 2016;75:1615–21.) combine both low disease activity (SLEDAI score of ≤4, PGA >=1 no flare, no…
Abstract Number: 1890 • ACR Convergence 2020
Daily Management of Patients with Axial Spondyloarthritis: Self-monitoring of Disease Activity with a Smartphone App Is Feasible – a Proof of Concept Study
Uta Kiltz¹, Robin Kempin¹, Jutta Richter², Anna Schlegel¹, Xenofon Baraliakos¹, Styliani Tsiami³, Ioana Andreica¹, Bjoern Buehring⁴, David Kiefer¹ and Juergen Braun¹, ¹Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, ²Rheumatology and Hiller Research Unit, Heinrich-Heine-University Duesseldorf, Medical Faculty, Duesseldorf, Germany, Duesseldorf, Germany, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, ⁴Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Velbert, Germany
Background/Purpose: Assessment and monitoring of disease activity and functioning is of major importance for the course of axial spondyloarthritis (axSpA). This is equally important for…
Abstract Number: 0139 • ACR Convergence 2020
Routine Assessment of Patient Index Data (RAPID) 3 as a Predictor of Weight Reduction in Rheumatology Patients Undergoing Bariatric Surgery
John Byun¹, Meenakshi Jolly², Todd Beck¹ and Sobia Hassan², ¹Rush University, Chicago, ²Rush University, Chicago, IL
Background/Purpose: Obesity is associated with higher disease activity in many rheumatologic diseases with evidence of improvement following bariatric surgery. Despite the impressive average weight loss…
Abstract Number: 0275 • ACR Convergence 2020
Paradoxical Relationship Between Disease Activity and Satisfaction with Care in Lupus
Sana Afroz¹, Ailda Nika², Winston Sequeira³, Joel Block⁴, Patricia Katz⁵ and Meenakshi Jolly², ¹RUMC, chicago, IL, ²Rush University, Chicago, IL, ³Rush University Medical Center, Oak Brook, IL, ⁴Rush University Medical Center, Chicago, ⁵University of California, San Francisco, Novato, CA
Background/Purpose: Satisfaction with care (SC) is increasingly being used as a surrogate of QOC, with growing emphasis on optimizing SC/patient experience in health care. We…
Abstract Number: 0459 • ACR Convergence 2020
Autologous Hematopoietic Stem Cell Transplantation for Behçet’s Disease: A Retrospective Survey of Patients Treated in Europe, on the Behalf of the Autoimmune Diseases Working Party of the European Society for Blood and Bone Marrow Transplantation
Mathieu Puyade¹, Patel Amit², Yeong Jer Lim³, Norbert Blank⁴, Manuela Badoglio⁵, Francesca Gualandi⁶, David D Ma⁷, Raffaella Greco⁸, Natalia Maximova⁹, Tobias Alexander¹⁰ and John A Snowden¹¹, ¹Service de Médecine Interne et Maladies Infectieuses ,CIC-1402 Centre Hospitalier Universitaire de Poitiers, Poitiers, France, ²The Christie NHS Foundation Trust, Manchester, United Kingdom, ³University of Liverpool, Liverpool, United Kingdom, ⁴Department of Hematology, Oncology and Rheumatology, Internal Medicine V, University Hospital of Heidelberg, Eppelheim, Germany, ⁵EBMT ADWP Office, Paris, France, ⁶U.O. EMATOLOGIA Centro Trapianti Midollo - OSPEDALE POLICLINICO SAN MARTINO, GENOVA, Italy, ⁷Department of Haematology and BM Transplantation, St Vincent’s Hospital Sydney and St Vincent’s Clinical School, Faculty of Medicine, Sidney, New South Wales, Australia, ⁸Ematologia Trapianto Midollo San Raffaele, Milano, Italy, ⁹Institute for Maternal and Child Health – IRCCS Burlo Garofolo, Trieste, Italy, ¹⁰Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Rheumatology and Clinical Immunology, Berlin, Deutsches Rheuma-Forschungszentrum, Berlin, Germany, ¹¹Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom
Background/Purpose: Behçet’s Disease (BD) is a rare autoimmune disease mostly presenting with recurrent oral and genital aphtosis, ulcers, and uveitis. Rare patients are refractory to…

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