Abstracts tagged "Disease Activity"

Abstract Number: 862 • 2013 ACR/ARHP Annual Meeting
Ten-Year Incidence of Self-Reported Nonvertebral Fractures in 9,720 Japanese Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study
Kensuke Ochi¹, Takefumi Furuya¹, Eisuke Inoue², Katsunori Ikari¹, Atsuo Taniguchi², Hisashi Yamanaka¹ and Shigeki Momohara², ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan
Ten-Year Incidence of Self-reported Nonvertebral Fractures in 9,720 Japanese Patients with Rheumatoid Arthritis: A Prospective Observational Cohort Study Background/Purpose: Although rheumatoid arthritis (RA) is a…
Abstract Number: 346 • 2013 ACR/ARHP Annual Meeting
Rheumatoid Arthritis, a More Severe Disease Than Psoriatic Arthritis? A Comparison Of Disease Activity In Patients With Psoriatic Arthritis and Rheumatoid Arthritis From The Swedish Early Psoriatic Arthritis Registry (SwePsA) and The Swedish Rheumatology Registry For Early RA (SRR)
Gerd-Marie Alenius¹, Tomas Husmark², Elke Theander³, Per Larsson⁴, Mats Geijer⁵, Annika Teleman⁶ and Ulla R. C. Lindqvist⁷, ¹Department of Public Health and Clinical Medicine, Rheumatology, Umeå University, Umeå, Sweden, ²Department of Rheumatology, Falu Hospital, Falun, Sweden, ³Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁴Dept of Rheumatology, Karolinska University Hospital, Stockholm, Sweden, ⁵Skåne University Hospital, Lund, Center for Medical Imaging and Physiology, Lund, Sweden, ⁶Department of Rheumatology, Spenshult Hospital, Oskarstrom, Sweden, ⁷Department of Medical Sciences, Rheumatology, University Hospital, Uppsala university, Uppsala, Sweden
Background/Purpose: In clinical practise patients with psoriatic arthritis (PsA) seem to have milder disease expression compared with patients having rheumatoid arthritis (RA). Studies have, however,…
Abstract Number: 2905 • 2013 ACR/ARHP Annual Meeting
Demethylation of ITGAL (CD11a) regulatory sequences in CD4+T lymphocytes of Systemic Sclerosis
Yaoyao Wang¹, Ye Shu², Qing Wang¹, Ming Zhao¹, Gongping Liang¹, Qianjin Lu¹ and Rong Xiao¹, ¹Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China, ²Department of Dermatology, Hunan Children's Hospital, Changsha, China

Background/Purpose: Systemic sclerosis (SSc) is an autoimmune connective tissue disease epitomized numerous cellular and humoral immunological abnormalities. The immune system undoubtedly plays a pivotal…
Abstract Number: 2508 • 2013 ACR/ARHP Annual Meeting
Clinical and Serological Discordance In The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) Cohort
Murray B. Urowitz¹, Dafna D. Gladman¹, Nicole Anderson¹ and Systemic Lupus Erythematosus International Collaborating Clinics SLICC², ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Anti-DNA antibodies and serum complement levels are considered important biomarkers for disease activity in SLE. Despite this many SLE patients present serologically active (positive…
Abstract Number: 2238 • 2013 ACR/ARHP Annual Meeting
Comparison Of The Long-Term Outcome For Rheumatoid Arthritis Patients With persistent Moderate Disease Activity Or Disease Remission During The First Year After Diagnosis: Data From The Espoir Cohort
Bernard Combe¹, Isabelle Logeart², M. Belkacemi³, S Dadoun⁴, Jean-Pierre Daurès⁵ and Maxime Dougados⁶, ¹Rheumatology, Lapeyronie Hospital, Montpellier I university, Montpellier, France, ²Pfizer, Paris, France, ³CHRU Montpellier, Montpellier, France, ⁴Paris-Pitié Salpêtrière University Hospital, Paris, France, ⁵Service BESPIM, CHU, Nimes, France, ⁶Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France
Background/Purpose: The Treat to Target and EULAR recommendations highlighted the need for achieving and maintaining remission in patients with early RA. We investigated if early…
Abstract Number: 1708 • 2013 ACR/ARHP Annual Meeting
Can People With Rheumatoid Arthritis Self Monitor Their Disease Activity?
Noura AL Osaimi¹, Erin Carruthers², Charles H Goldsmith^3,4, Paul M Adam⁵ and Diane Lacaille^1,6, ¹Medicine, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Centre of Canada, Richmond, BC, Canada, ³Biostatistics, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁴Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁵Rheumatology Liaison, Mary Pack Arthritis Centre, Vancouver, BC, Canada, ⁶Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada
Background/Purpose: In rheumatoid arthritis (RA) the target for treatment is clinical remission or minimal disease activity. Active involvement of patients in monitoring their own disease…
Abstract Number: 1368 • 2013 ACR/ARHP Annual Meeting
The Effect Of Vitamin D On Early Rheumatoid Arthritis: A Retrospective Cohort Analysis
Faye A H Cooles¹, Arthur G Pratt^2,3,4, Wan-Fai Ng^3,5, Terry J Aspray³ and John D Isaacs², ¹Musculoskeletal Research Group, Newcastle University, Newcastle upon Tyne, United Kingdom, ²Institute of Cellular Medicine (Musculoskeletal Research Group), NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals Foundation Trust and Newcastle University, Newcastle upon Tyne, United Kingdom, ³Musculoskeletal Directorate, The Freeman Hospital, Newcastle upon Tyne, United Kingdom, ⁴Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁵Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom
Background/Purpose: There is increasing evidence that vitamin D has immunoregulatory properties in autoimmunity. In established rheumatoid arthritis (RA) there appears to be an inverse association…
Abstract Number: 812 • 2013 ACR/ARHP Annual Meeting
Alveolar Bone Loss Is Associated With Disease Activity and ACPA Expression In Rheumatoid Arthritis
Ted R. Mikuls¹, Jeffrey Payne², Fang Yu³, Geoffrey M. Thiele⁴, Shawneen Gonzalez², Jeffrey Markt⁵, Jeremy Sokolove⁶, William H. Robinson⁷, Richard J. Reynolds⁸, Grant W. Cannon⁹, David McGowan¹⁰, Gail S. Kerr¹¹, Robert Redman¹², Andreas M. Reimold¹³, Garth Griffiths¹⁴, Mark Beatty², Marian Schmid², Paul Johnson², Debra Bergman¹⁵, Bartlett C. Hamilton III¹⁶, Alan R. Erickson¹ and James R. O'Dell¹⁷, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, ⁶Stanford University, Palo Alto, CA, ⁷Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, ⁸Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁹Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ¹⁰Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, ¹¹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ¹²Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, ¹³Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹⁴Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹⁵Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ¹⁶University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ¹⁷Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Periodontitis (PD) has been implicated in rheumatoid arthritis (RA) pathogenesis including the expression of anti-citrullinated protein antibody (ACPA). ACPA, in turn, have been shown…
Abstract Number: 300 • 2013 ACR/ARHP Annual Meeting
Higher Disease Activity In Psoriatic Arthritis Is Associated With Elevated Total Cholesterol and Triglycerides
Monalyn Labitigan¹, Asha Shrestha¹, George W. Reed^2,3, Robert P. Magner⁴, Nicole Jordan⁵, Joel M. Kremer⁶, Jeffrey D. Greenberg⁷, Asena Bahce-Altuntas⁵ and Anna R. Broder¹, ¹Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²CORRONA, Inc., Southborough, MA, ³Orthopedics, University of Massachusetts Medical School, Worcester, MA, ⁴University of Massachusetts Medical School, Worcester, MA, ⁵Department of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁶Center for Rheumatology, Albany Medical College, Albany, NY, ⁷Departments of Medicine (Rheum Div) and Hospital for Joint Diseases, New York Hospital for Joint Diseases, New York, NY
Background/Purpose: Psoriatic Arthritis (PsA) is linked to both obesity and an increased cardiovascular risk. However, the relationship between PsA disease activity and lipids, a major cardiovascular…
Abstract Number: 2879 • 2013 ACR/ARHP Annual Meeting
Prognostic Value Of Minor Salivary Gland Assessments In Primary Sjögren’s Syndrome
Anna Risselada¹, A.a. Kruize², J.A.G. van Roon³, F.P.J.G. Lafeber⁴ and J.W.J. Bijlsma⁴, ¹Clinical immunology and Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ²Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ³Rheumatology & Clinical Immunology/Lab Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Salivary gland assessment is important for diagnosing primary Sjögren’s syndrome (pSS), as the lymphocytic focus score (LFS) is part of pSS classification criteria. Quantitative…
Abstract Number: 2511 • 2013 ACR/ARHP Annual Meeting
Multicenter Validation Of The Lupus Activity Scoring Tool (LAST) As Compared To The Selena Sledai (SS) Modification
Majed M. Khraishi¹, Rana Aslanov², Sanjay Dixit³, Krista Fudge⁴, Vandana Ahluwalia⁵ and Sarah Khraishi⁶, ¹Nexus Clinical Research, St John's, NF, Canada, ²Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada, ⁵Past President, Ontario Rheumatology Association, Brampton, ON, Canada, ⁶Nexus Clinical Research, Memorial University of Newfoundland, St.John's, NF, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic immune modulated disease with variable clinical manifestations. New advances in the management of SLE mandated closer monitoring…
Abstract Number: 2241 • 2013 ACR/ARHP Annual Meeting
Assessing Significant Flares In Rheumatoid Arthritis: Validity Of The Outcome Measures In Rheumatology Preliminary Flare Questions In The Canadian Early Arthritis Cohort
Susan J. Bartlett^1,2, Clifton O. Bingham III³, Ernest Choy⁴, Juan Xiong⁵, Gilles Boire⁶, Boulos Haraoui⁷, Janet E. Pope^8,9, J. Carter Thorne¹⁰, Carol A. Hitchon¹¹, Diane Tin¹², Edward C. Keystone¹³ and Vivian P. Bykerk^13,14, ¹Clinical Epidemiology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴Section of Rheumatology, Cardiff University, Institute of Infection and Immunity, Cardiff, United Kingdom, ⁵Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁷Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, ⁸St Joseph Health Care, London, ON, Canada, ⁹Univ of Western Ontario, London, ON, Canada, ¹⁰Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹Rheumatology, University of Manitoba, Winnipeg, MB, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada, ¹⁴Rheumatology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) flares are common, poorly defined, and understudied. A tool is needed to measure significant RA flares that may signal need for…
Abstract Number: 1667 • 2013 ACR/ARHP Annual Meeting
Serum S100A8/S100A9 and S100A12 As a Marker Of Disease Activity In Giant Cell Arteritis
Jason Springer¹, Dirk Holzinger², Gary S. Hoffman³, Paul A. Monach⁴, Thomas Hamilton⁵, Carol A. Langford⁶, Dirk Foell⁷, David Cuthbertson⁸, Colin O'Rourke⁹, Simon Carette¹⁰, Nader A. Khalidi¹¹, Carol McAlear¹², Christian Pagnoux¹⁰, Philip Seo¹³, Kenneth J. Warrington¹⁴, Steven R. Ytterberg¹⁵, Thomas Vogl¹⁶, Peter A. Merkel¹⁷, Johannes Roth¹⁸ and Rula Hajj-Ali¹⁹, ¹Division of Allergy, Clinical Immunology and Rheumatology, University of Kansas Medical Center, Kansas City, KS, ²Institute of Immunology, University Muenster, Muenster, Germany, ³Center for Vasculitis Care and Research, Cleveland Clinic Foundation, Cleveland, OH, ⁴Rheumatology, Boston University, Boston, MA, ⁵Cleveland Clinic, Cleveland, OH, ⁶Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, ⁷Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ⁸Department of Biostatistics, University of South Florida, Tampa, FL, ⁹Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ¹⁰Division of Rheumatology, University of Toronto, Toronto, ON, Canada, ¹¹Internal Medicine/Rheumatology, McMaster University, Hamilton, ON, Canada, ¹²University of Pennsylvania, Philadelphia, PA, ¹³Rheumatology Division, Johns Hopkins Vasculitis Center, Johns Hopkins University, Baltimore, MD, ¹⁴Division of Rheumatology, Mayo Clinic, Rochester, MN, ¹⁵Rheumatology Division, Mayo Clinic, Rochester, MN, ¹⁶Institute of Immunology, University of Muenster, Muenster, Germany, ¹⁷Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA, ¹⁸Immunology, Institute of Immunology University of Muenster, Muenster, Germany, ¹⁹Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: The S100 proteins (S100A8/9 complex and S100A12) are calcium binding proteins expressed during myeloid differentiation. S100 proteins are phagocyte-specific proteins that have been demonstrated…
Abstract Number: 1341 • 2013 ACR/ARHP Annual Meeting
Significantly Less Glucocorticoids and Better Patient-Reported Outcomes In Women With Early Inflammatory Arthritis Using Oral Contraceptives Compared To Never Users
Gisela Westhoff¹, Rainer H. Straub², Frank Buttgereit³, Johanna Callhoff⁴ and Angela Zink⁵, ¹Epidemiology Unit, German Rheumatism Research Center Berlin, Berlin, Germany, ²Department of Internal Medicine I, Laboratory of Exp. Rheumatology and Neuroendocrino-Immunology, University Hospital of Regensburg, Regensburg, Germany, ³Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴German Rheumatism Research Center, Berlin, Germany, ⁵German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany
Background/Purpose: Data on the effects of oral contraceptives (OC) on the course of inflammatory arthritis (IA) are controversial. However, a recent analysis of data from…
Abstract Number: 792 • 2013 ACR/ARHP Annual Meeting
Methotrexate Polyglutamates in Erythrocytes Are Associated With Lower Disease Activity in Juvenile Idiopathic Arthritis Patients
Maja Bulatovic Calasan¹, Ethan den Boer², Maurits C.F.J. De Rotte³, S.J. Vastert⁴, Sylvia Kamphuis⁵, Robert De Jonge³ and Nico M. Wulffraat⁶, ¹Paediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ²Clinical Chemistry, Erasmus MC University Medical Center, Rotterdam, Netherlands, ³Clinical Chemistry, Erasmus Medical Center, Rotterdam, Netherlands, ⁴Pediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Pediatric Rheumatology, Eramus MC Sophia Children's Hospital, Rotterdam, Netherlands, ⁶Pediatric Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Methotrexate polyglutamates (MTX-PG) could be biomarkers of MTX response and adverse effects and could thus be used as a therapeutic drug monitoring (TDM) tool to steer tailor-made therapeutic…

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