Abstracts tagged "Disability"

Abstract Number: 2540 • 2016 ACR/ARHP Annual Meeting
The Longitudinal Impact of Biologic Use on Disability within a RA Registry
N A Shadick¹, Nicole Gerlanc², M Frits¹, Bradley S. Stolshek³, Brenna Brady², Christine Iannaccone⁴, David Collier⁵, Jing Cui⁶, Alex Mutebi⁷ and Michael Weinblatt⁴, ¹Brigham and Women's Hospital, Boston, MA, ²Health Analytics, LLC, Columbia, MD, ³Amgen, Thousand Oaks, CA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁵Amgen Inc., Thousand Oaks, CA, ⁶Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁷Global Health Economics, Amgen, Thousand Oaks, CA
Background/Purpose: Biologics have become the standard of care for treating moderate to severe rheumatoid arthritis (RA) in patients with an inadequate response to small molecule…
Abstract Number: 2922 • 2016 ACR/ARHP Annual Meeting
Disability, Fatigue, and Their Associates in Early Diffuse Cutaneous Systemic Sclerosis
Ariane L. Herrick¹, Sébastien Peytrignet², Xiaoyan Pan³, Roger Hesselstrand⁴, Luc Mouthon⁵, László Czirják⁶, Madelon C. Vonk⁷, Oliver Distler⁸, Joerg H.W Distler⁹, Edith Brown³, Kim Fligelstone³, Rachel Ochiel¹⁰, William Gregory¹¹, Alan Silman¹², Mark Lunt¹³ and Christopher Denton¹⁴, ¹Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Manchester, United Kingdom, ²Manchester Academic Health Sciences Centre, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ³Manchester Academic Health Science Centre, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ⁴Department of Rheumatology, Lund University, Lund, Sweden, ⁵Internal Medicine, Hopital Cochin, Paris, France, ⁶Department of Rheumatology and Immunology, University of Pécs, Faculty of Medicine, Pécs, Hungary, ⁷Department of the Rheumatic Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁸Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁹Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, ¹⁰Royal Free London NHS Foundation Trust, London, United Kingdom, ¹¹Rehabilitation Services, Salford Royal NHS Foundation Trust, Salford, United Kingdom, ¹²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ¹³Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ¹⁴Centre for Rheumatology, Royal Free Hospital, London, Great Britain
Background/Purpose: ESOS (European Scleroderma Observational Study) was a prospective observational study of 326 patients with early diffuse cutaneous systemic sclerosis (dcSSc) from 50 centres. Here…
Abstract Number: 2091 • 2015 ACR/ARHP Annual Meeting
Influence of Increasing Physical Activity on Longitudinal Changes in Disability Status Among Inactive Older Adults
Jing Song¹, Abigail Gilbert², Rowland W. Chang³, Christine Pellegrini⁴, Linda S. Ehrlich-Jones⁵, Julia (Jungwha) Lee⁶, Daniel Pinto⁷, Pamela Semanik⁸, Leena Sharma⁹, C. Kent Kwoh¹⁰, Rebecca D. Jackson¹¹ and Dorothy D. Dunlop¹², ¹Institute for Healthcare Studies, Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Dept Preventive Med, Northwestern Univ, Chicago, IL, ⁴Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Research CROR, Rehabilitation Institute Chicago, Chicago, IL, ⁶Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, ⁸College of Nursing, Rush University, Chicago, IL, ⁹Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ¹⁰Rheumatology, University of Arizona, Tucson, AZ, ¹¹Ohio State University, Columbus, OH, ¹²Inst Hlthcare Studies, Northwestern Univ, Chicago, IL
Background/Purpose: An estimated 21% of disability attributed to arthritis is related to inactivity. This study analyzed data from the Osteoarthritis Initiative (OAI) to evaluate the…
Abstract Number: 2413 • 2015 ACR/ARHP Annual Meeting
Contributors to Walking Disability in People with Osteoarthritis: Results from a Population-Based Cohort
Lauren King¹, Tetyana Kendzerska^1,2,3 and Gillian Hawker^1,2,3, ¹Department of Medicine, University of Toronto, Toronto, ON, Canada, ²Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ³Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Osteoarthritis (OA) is associated with functional limitations, including difficulty walking. However, comorbid disease is common in people with OA and may also be associated…
Abstract Number: 438 • 2015 ACR/ARHP Annual Meeting
Comparison of the Stanford and Indian Health Assessment Questionnaires for Disability Outcomes in a Phase 3, Randomized, Double-Blind, Active Comparator Study of Infliximab and Biosimilar Infliximab BOW15 in Rheumatoid Arthritis
Arvind Chopra¹, Manjit Saluja², Alastair Knight³, Lucy Shneyer⁴, Cheryl Lassen⁵, Michael Wyand⁶ and Jonathan Kay⁷, ¹Rheumatology, Centre for Rheumatic Diseases, Pune 411001, India, ²Centre for Rheumatic Diseases, Pune 411001, India, ³Data Management, Evicom Ltd, Twickenham, United Kingdom, ⁴Shneyer Statistics, Denville, NJ, ⁵Epirus Biopharmaceuticals, Zug, Switzerland, ⁶Epirus Biopharmaceuticals, Boston, MA, ⁷University of Massachussets Medical School, Worcester, MA
Background/Purpose: The Stanford Health Assessment Questionnaire (HAQ) includes several questions that are more relevant to rheumatoid arthritis (RA) patients in Western countries than to those…
Abstract Number: 907 • 2015 ACR/ARHP Annual Meeting
The Natural History of an Inception Cohort of Patients with Inflammatory Polyarthritis Followed for 20 Years: Disease Activity, Disability and Surgery
James Gwinnutt¹, Deborah P.M. Symmons¹, Alex J Macgregor², Jacqueline Chipping², Tarnya Marshall² and Suzanne M. Verstappen¹, ¹ARC Epidemiology, Stopford Building, ARC Epidemiology Unit, the University of Manchester, Manchester, United Kingdom, ²Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom
Background/Purpose: There is little data on the 20 year outcome of patients with inflammatory polyarthritis (IP). Hence the aim of this study was to describe…
Abstract Number: 1434 • 2015 ACR/ARHP Annual Meeting
Neuropathic Pain in Patients with Rheumatoid Arthritis: Relation with Clinical Variables
Ferda Kaygisiz¹, Pinar Borman² and Aynur Karagoz³, ¹Dept of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey, ²Department of Physical Medicine and Rehabilitation, University of Hacettepe Faculty of Medicine, Ankara, Turkey, ³Dept of Physical Medicine and Rehabilitation, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey
Background/Purpose: There are few studies in the literature indicating that neuropathic pain occurs in rheumatoid arthritis (RA). The aim of this cross sectional study was…
Abstract Number: 1536 • 2015 ACR/ARHP Annual Meeting
Sensorineural Hearing Impairment and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients without Traditional Cardiovascular Risk Factors
Hector Macias Reyes¹, Sergio Duran-Barragan^2,3, Cynthia Cardenas Contreras⁴, Cesar Chavez Martin⁴, Eduardo Gomez², Rosa Navarro Hernandez², Jorge Aguilar Arreola^2,5, Paul Perez-Cruz^2,5, Carlos Yanowsky Gonzalez² and Monica Vazquez-Del Mercado^2,5, ¹1. Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, ²Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Instituto de Investigación en Reumatología y del Sistema Musculoesquelético, Guadalajara, Mexico, ³Clinica de Investigación en Reumatología y Obesidad, Guadalajara, Mexico, ⁴Hospital Civil Fray Antonio Alcalde, Guadalajara, Mexico, ⁵Servicio de Reumatología, División de Medicina Interna, Hospital Civil Dr. Juan I. Menchaca, Guadalajara, Mexico
Background/Purpose: Rheumatoid arthritis (RA) is characterized by inflammation of the synovial membrane of the diarthrodial joints which include arthrodesis of the middle ear, (incudomalleolar and…
Abstract Number: 1557 • 2015 ACR/ARHP Annual Meeting
The Impact of Hindfoot Deformity on Disability of Korean Patients with Rheumatoid Arthritis
Hye-Jin Jeong¹, Il Woong Sohn¹, Seung Lee¹, Seung Taek Song¹, Soo-Kyung Cho² and Yoon-Kyoung Sung², ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Rheumatoid arthritis (RA) commonly involves the hindfoot, but this part is frequently overlooked when caring for patients with multiple joints pain and deformity. For…
Abstract Number: 1729 • 2015 ACR/ARHP Annual Meeting
Predictors and Clinical Factors Associated with Change in Spinal Inflammation Assessed on MRI over 2 Years: Data from Tasmanian Ankylosing Spondylitis Study
Hussain Ijaz Khan¹, Louisa Chou², Patricia Lewis³, Anitra Wilson³, Janet Millner⁴ and Jane Zochling³, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, Hobart, Australia, ⁴Physiotherapy, Royal Hobart Hospital, Hobart, Australia
Background/Purpose: Ankylosing Spondylitis (AS) is debilitating disease affecting the axial skeleton which is often difficult to diagnose in early stages. Magnetic Resonance Imaging (MRI) is…
Abstract Number: 2053 • 2015 ACR/ARHP Annual Meeting
Adjustment of Skeletal Muscle Mass Estimates for the Extent of Adiposity Strengthens Relationships with Functional Outcomes in Rheumatoid Arthritis
Joshua Baker¹, Jon Giles², Mary Leonard³, David Weber⁴, Jin Long⁵, Erik Jorgenson⁶ and Patricia P. Katz⁷, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Rheumatology, Columbia University Medical Center, NY, NY, ³Stanford University, Palo Alto, CA, ⁴Rochester University, Rochester, NY, ⁵Children's Hospital of Philadelphia, Philadelphia, PA, ⁶University of Pennsylvania, Philadelphia, PA, ⁷Rheumatology, UCSF, SF, CA
Background/Purpose: Skeletal muscle loss in rheumatoid arthritis (RA) has been described in association with poor physical functioning. Greater adiposity is simultaneously associated with both greater…
Abstract Number: 2975 • 2014 ACR/ARHP Annual Meeting
Residual Large Joint Synovitis By Power Doppler Ultrasonography Is Associated with Higher Disease Activity and Significant Impact of Disease in Multi-Ethnic Asian Patients with Established Rheumatoid Arthritis
Yu Xiao Guo¹, Manjari Lahiri^2,3 and Peter Cheung^2,3, ¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, ²Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, ³Division of Rheumatology, National University Hospital, Singapore, Singapore
Background/Purpose Regular monitoring of disease activity with appropriate modification of disease-modifying anti-rheumatic drug (DMARD) therapy results in improved radiographic and functional outcomes in patients with…
Abstract Number: 2944 • 2014 ACR/ARHP Annual Meeting
Sedentary Time Is an Independent Risk Factor for Disability Onset Among Adults at Elevated Risk: Prospective Cohort Study
Jungwha Lee¹, Jing Song², Barbara Ainsworth³, Rowland W. Chang⁴, Linda S. Ehrlich-Jones⁵, Christine Pellegrini⁶, Pamela Semanik⁷, Dorothy D. Dunlop² and Leena Sharma⁸, ¹Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Arizona State University, Pheonix, AZ, ⁴Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Rehabilitation Institute of Chicago, Chicago, IL, ⁶Center for Behavioral Health, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Rush University, Chicago, IL, ⁸Northwestern University, Chicago, IL
Background/Purpose: Disability threatens personal independence and is a major driver of health care costs. Physical activity has been shown to prevent disability. Sedentary behavior, already…
Abstract Number: 2525 • 2014 ACR/ARHP Annual Meeting
Infliximab Versus Conventional Combination Treatment and Work Loss in Early RA over 7 Years: A Randomized Trial
Jonas K Eriksson¹, Heather Miller², Johan A Karlsson³, Ingemar F Petersson⁴, Sofia Ernestam⁵, Pierre Geborek³, Ronald F van Vollenhoven² and Martin Neovius¹, ¹Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ²ClinTRID, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ³Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ⁴Section of Orthopedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden, ⁵Department of Learning, Informatics and Medical Education (LIME), Karolinska Institutet, Stockholm, Sweden
Background/Purpose: The introduction of TNF inhibitors has improved the treatment of RA, but at a substantial cost. The randomized Swefot trial compared the addition of…
Abstract Number: 2273 • 2014 ACR/ARHP Annual Meeting
Does a Standardized Multidisciplinary Approach Improve Outcomes for Children with NMDA Receptor Antibody Encephalitis? : A Preliminary Assessment of a Single Center Experience
Mered Parnes¹, Amber Stocco², Trung Nguyen³, Jun Teruya⁴, Jeanine Graf³ and Eyal Muscal⁵, ¹Child Neurology, Baylor College of Medicine, Houston, TX, ²Integris Pediatric Neurology, Oklahoma City, OK, ³Pediatrics-critical care, Baylor College of Medicine, Houston, TX, ⁴Pathology, Baylor College of Medicine, Houston, TX, ⁵Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Houston, TX
Background/Purpose: NMDA receptor antibody encephalitis (NMDAR) is a potentially devastating isolated autoimmune condition affecting children and young adults that was mostly unrecognized prior to 2007.…

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