Abstracts tagged "diagnosis"

Abstract Number: 2585 • 2013 ACR/ARHP Annual Meeting
Left Ventricular Dysfunction Reflected By Higher Serum Brain Natriuretic Peptide Accounts For Poorer Prognosis Of Pulmonary Arterial Hypertension Associated With Systemic Sclerosis
Sumiaki Tanaka¹, Yoshiyuki Arinuma¹, Tatsuhiko Wada¹, Tatsuo Nagai², Jun Okada³ and Shunsei Hirohata¹, ¹Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, ²Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan, ³Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan
Background/Purpose: Recentry, development of potent effective newer drugs for pulmonary arterial hypertension (PAH) have resulted in improving survival of the patients. However, the prognosis of…
Abstract Number: 2519 • 2013 ACR/ARHP Annual Meeting
A Systemic Lupus Erythematosus (SLE) Diagnostic Test Based On DNA Methylation Signatures From Peripheral Blood Mononuclear Cells
David W. Anderson¹, Robert Shoemaker², Kurt Krummel³, Zachary Hornby⁴ and Jonathan E. Lim¹, ¹Research and Development, IGNYTA, Inc., San Diego, CA, ²Bioinformatics, IGNYTA, Inc., San Diego, CA, ³Research and Development-Assay Development, IGNYTA, Inc., San Diego, CA, ⁴Business Development, IGNYTA, Inc., San Diego, CA
Background/Purpose: The heterogeneous nature of SLE and a lack of reliable biomarkers make SLE a challenge to classify in patients. A differential diagnosis of SLE…
Abstract Number: 2288 • 2013 ACR/ARHP Annual Meeting
Novel Biomarkers From Peripheral Blood Mononuclear Cells Indicate Disease Activity In Rheumatoid Arthritis Patients
Jason Ptacek¹, Rachael Hawtin², Brent Louie¹, Erik Evensen¹, James Cordeiro¹, Barbara Mittleman¹, Michelle Atallah¹, Alessandra Cesano², Clifton O. Bingham III³, Stacey Cofield⁴, Jeffrey R. Curtis⁵, Maria I. Danila⁴, Richard A. Furie⁶, MC Genovese⁷, Marc C. Levesque⁸, Larry W. Moreland⁸, Peter A. Nigrovic⁹, James R. O'Dell¹⁰, William H. Robinson¹¹, Nancy A. Shadick⁹, E. William St Clair¹², Christopher C. Striebich¹³, Geoffrey M Thiele¹⁴, Peter K. Gregersen⁶ and S. Louis Bridges Jr.⁴, ¹Nodality, Inc., South San Francisco, CA, ²Nodality Inc., South San Francisco, CA, ³Rheumatology, Johns Hopkins University, Baltimore, MD, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Epidemiology, University of Alabama at Birmingham, School of Public Health, Birmingham, AL, ⁶The Feinstein Institute for Medical Research and North Shore-Long Island Jewish Health System, Lake Success, NY, ⁷Stanford University, Palo Alto, CA, ⁸University of Pittsburgh, Pittsburgh, PA, ⁹Brigham and Women's Hospital/Harvard University, Cambridge, MA, ¹⁰Veteran Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ¹¹VA Palo Alto Health Care System and Stanford University, Palo Alto, CA, ¹²Medicine, Duke Unversity Medical Center, Durham, NC, ¹³University of Colorado Denver, Aurora, CO, ¹⁴Omaha VA and the University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Biomarkers reflecting immune function and associating with disease activity can help stratify rheumatoid arthritis (RA) patients (pts) in practice and in clinical trials.…
Abstract Number: 2160 • 2013 ACR/ARHP Annual Meeting
The Journey to Diagnosis in As/Axial Spondyloarthritis – the Psychological Impact of Delay
Jane Martindale^1,2 and Lynne Goodacre², ¹Physiotherapy, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, United Kingdom, ²Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom
Background/Purpose: It is not uncommon for 8 to 11 years to pass between symptoms onset and definitive diagnosis of AS/axial SpA (Gran 1997, Feldtkeller, 2003).…
Abstract Number: 804 • 2012 ACR/ARHP Annual Meeting
A Comparison of the Nociceptive Flexion Reflex, Pressure Algometry and Summated Widespread Pain in the Diagnosis of Fibromyalgia
Robert M. Bennett¹, Kim D. Jones² and Janice Hoffman³, ¹Medicine & Nursing, Oregon Health & Science Univ, Portland, OR, ²Research & Develop, Oregon Health Sciences University, Portland, OR, ³Office of Research Development & Support, Oregon Health & Science University, Portland, OR
Background/Purpose: To reevaluate the usefulness of the nociceptive flexion reflex (NFR) in distinguishing between FM patients and healthy controls, compared to computerized algometry and a…
Abstract Number: 778 • 2012 ACR/ARHP Annual Meeting
Spinal MRI Has Little Incremental Diagnostic Value Compared with MRI of the Sacroiliac Joints Alone in Early Spondyloarthritis
Ulrich Weber¹, Veronika Zubler², Zheng Zhao³, Robert GW Lambert⁴, Stanley Chan⁵, Susanne Juhl Pedersen⁶, Mikkel Ostergaard⁷ and Walter P. Maksymowych⁸, ¹Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ²Radiology, Balgrist University Hospital, Zurich, Switzerland, ³Department of Rheumatology, University of Alberta and PLA General Hospital, Beijing, PR China, Beijing, AB, China, ⁴Radiology, University of Alberta, Edmonton, AB, Canada, ⁵Division of Ophthalmology, University of Alberta, Edmonton, AB, Canada, ⁶Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, ⁷Dept of Rheumatology RM, Copenhagen University Hospital, Glostrup, Denmark, ⁸Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The definition of a positive MRI as major criterion in the Assessment of SpondyloArthritis classification criteria for axial spondyloarthritis (SpA) is based on MRI…
Abstract Number: 548 • 2012 ACR/ARHP Annual Meeting
Assessment of the T1-Weighted Sequence Is Essential in Defining a Positive MRI Scan of the Sacroiliac Joints in Spondyloarthritis
Ulrich Weber¹, Veronika Zubler², Susanne Juhl Pedersen³, Kaspar Rufibach⁴, Robert GW Lambert⁵, Stanley Chan⁶, Mikkel Ostergaard⁷ and Walter P. Maksymowych⁸, ¹Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ²Radiology, Balgrist University Hospital, Zurich, Switzerland, ³Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, ⁴Institute for Social and Preventive Medicine, Division of Biostatistics, University of Zurich, Zurich, Switzerland, ⁵Radiology, University of Alberta, Edmonton, AB, Canada, ⁶Division of Ophthalmology, University of Alberta, Edmonton, AB, Canada, ⁷Dept of Rheumatology RM, Copenhagen University Hospital, Glostrup, Denmark, ⁸Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Inflammation on MRI of the sacroiliac joints (SIJ) in patients with spondyloarthritis (SpA) is a major criterion in the Assessment of SpondyloArthritis (ASAS) classification…
Abstract Number: 192 • 2012 ACR/ARHP Annual Meeting
Clinical and Laboratory Findings in A Cohort of Italian Patients with Adult Onset Still’S Disease: The Role of IL-18 As A Disease Biomarker
Roberta Priori¹, Serena Colafrancesco², Carlo Perricone², Antonina Minniti², Cristiano Alessandri², Giancarlo Iaiani³ and Guido Valesini², ¹Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, ²Rheumatology Unit, Sapienza University of Rome, Rome, Italy, ³Department of Infectious Diseases and Tropical Medicine, Sapienza University of Rome, Rome, Italy
Background/Purpose: Adult Onset Still's Disease (AOSD) is a systemic inflammatory syndrome driven by interleukin (IL)-18. Since differential diagnosis between AOSD, sepsis and other inflammatory conditions…
Abstract Number: 2579 • 2012 ACR/ARHP Annual Meeting
Novel Autoantibodies to 14-3-3 Eta Are Highly Specific for Rheumatoid Arthritis
Walter P. Maksymowych¹, Désirée van der Heijde², R. Landewe³, Vivian P. Bykerk⁴ and Anthony Marotta⁵, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ⁴Rheumatology, Hospital for Special Surgery, New York, NY, ⁵Augurex Life Sciences Corp, North Vancouver, BC, Canada
Background/Purpose: Serum 14-3-3 eta, a protein biomarker that is differentially expressed in rheumatoid arthritis (RA), has been reported to add incrementally to rheumatoid factor (RF)…
Abstract Number: 199 • 2012 ACR/ARHP Annual Meeting
Joint, Hand and Feet Swelling As a Presenting Symptom of Hereditary Angioedema
Maria J. Gutierrez¹ and Timothy J. Craig², ¹Department of Pediatrics, Division of Pediatric Rheumatology. Department of Medicine, Section of Allergy and Immunology, Penn State College of Medicine Milton S. Hershey Medical Center, Hershey, PA, ²Department of Medicine. Division of Pulmonary, Allergy and Critical Care Medicine, Penn State College of Medicine Milton S. Hershey Medical Cente, Hershey, PA
Background/Purpose: Hereditary Angioedema (HAE) is a rare disorder caused by deficiency or impaired function of C1 esterase inhibitor. Early and accurate diagnosis of HAE is…
Abstract Number: 2528 • 2012 ACR/ARHP Annual Meeting
Hypertrophic Pachymeningitis: IgG4-Related Disease Is A Common Etiology
Zachary S. Wallace¹, Mollie Carruthers², Arezou Khosroshahi², Robert Carruthers³, Shweta Shinagare⁴, Anat Stemmer-Rachamimov⁴, Vikram Deshpande⁴ and John H. Stone², ¹Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ²Rheumatology, Massachusetts General Hospital, Boston, MA, ³Department of Neurology, Massachusetts General Hospital, Boston, MA, ⁴Pathology, Massachusetts General Hospital, Boston, MA
Background/Purpose: Hypertrophic pachymeningitis (HP) is an inflammatory condition in which the dura mater of the cranium or spine becomes thickened, leading to symptoms that result…
Abstract Number: 117 • 2012 ACR/ARHP Annual Meeting
Ultrasound for Diagnosis of Carpal Tunnel Syndrome – Comparison of Different Methods to Determine Median Nerve Volume and Value of Power Doppler Sonography
Christian Dejaco¹, Martin Stradner², Dorothea Zauner², Werner Seel³, Nicole E. Simmet³, Alexander Klammer², Kerstin Brickmann², Judith Gretler², Florentine Moazedi-Fürst², Rene Thonhofer², Rusmir Husic², Josef Hermann² and Stefan Quasthoff³, ¹Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom, ²Rheumatology, Medical University Graz, Graz, Austria, ³Neurology, Medical University Graz, Graz, Austria
Background/Purpose: Routine use of sonography for the diagnosis of carpal tunnel syndrome (CTS) is hampered by the lack of consensus regarding anatomical landmarks for the…
Abstract Number: 2532 • 2012 ACR/ARHP Annual Meeting
Whole Transcriptome Analysis in Relapsing Polychondritis: A Single-Center Analysis of 35 Patients
Laurent Arnaud¹, Alexis Mathian², Bruno Faivre³, Karim Dorgham³, Julien Haroche², Nathalie Costedoat-Chalumeau¹, Jean-Charles Piette², Guy Gorochov⁴ and Zahir Amoura¹, ¹Internal Medicine, Hôpital Pitié-Salpêtrière, AP-HP & UPMC Univ Paris 06, Paris, France, ²Department of Internal Medicine 2. Referal center for SLE/APS, Hôpital Pitié-Salpêtrière, AP-HP & UPMC Univ Paris 06, Paris, France, ³Institut National de la Santé et de la Recherche Médicale, INSERM UMR-S 945, Paris, France, ⁴Inserm UMRS945, Institut National de la Santé et de la Recherche Médicale, INSERM UMR-S 945, Paris, France
Background/Purpose: Relapsing polychondritis (RP) is a severe and episodic inflammatory condition involving cartilaginous structures, predominantly those of the ears, nose, and laryngotracheobronchial tree. Other affected…
Abstract Number: 87 • 2012 ACR/ARHP Annual Meeting
Prediction of Mortality in Rheumatoid Arthritis Using a Serum Cytokine Profile
Agustin Escalante¹, Roy W. Haas¹, Daniel F. Battafarano² and Inmaculada Del Rincon³, ¹Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Medicine / MCHE-MDR, Brooke Army Medical Ctr, San Antonio, TX, ³Rheumatology, University of Texas Health Science Center, San Antonio, TX
Background/Purpose: Cytokines are important in the pathogenesis of RA. Their concentration in the serum rises immediately prior to RA onset, and may be associated with…
Abstract Number: 2372 • 2012 ACR/ARHP Annual Meeting
Efficacy of Quantitative Analysis of Brainstem Atrophy On Magnetic Resonance Imaging for Diagnosis of Chronic Progressive Neuro-Behçet’s Disease
Hirotoshi Kikuchi¹, Maki Takayama², Yoshitaka Kimura², Kurumi Asako², Hajime Kono², Yasuo Ono¹ and Shunsei Hirohata³, ¹Department of Microbiology and Immunology, Teikyo University Shool of Medicine, Tokyo, Japan, ²Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, ³Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan
Background/Purpose : CNS involvement in Behçet's disease, usually called neuro-Behçet's disease (NB), can be classified into acute NB (ANB) and chronic progressive NB (CPNB) based…

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