Abstracts tagged "diabetes and osteoarthritis"

Abstract Number: 2178 • 2017 ACR/ARHP Annual Meeting
Metabolic Osteoarthritis: Relation of Cardiovascular Disease and Diabetes to Knee Osteoarthritis
Laura Kuusalo¹, David T. Felson², Carrie Brown³, Cora E. Lewis⁴, James Torner⁵ and Tuhina Neogi², ¹University of Turku and Turku University Hospital, Turku, Finland, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Boston University School of Public Health, Boston, MA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA
Background/Purpose: Metabolic changes or low-grade inflammation related to cardiovascular disease (CVD) and diabetes have been hypothesized to contribute to the development of OA. Prior studies…
Abstract Number: 1128 • 2015 ACR/ARHP Annual Meeting
Insulin-Induced Cartilage Degradation in Osteoarthritis Is Associated to Defective Autophagy
Beatriz Carames¹, Madalena Ribeiro^1,2, Paloma Lopez de Figueroa¹, Alexandrina Mendes² and Francisco J. Blanco¹, ¹Cartilage Biology Group. Rheumatology Division, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, ²Centre for Neuroscience and Cell Biology, University of Coimbra; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal
Background/Purpose: Autophagy, a key cellular quality control mechanism, is defective in Osteoarthritis (OA) and Type 2 Diabetes (T2D). T2D has been proposed as a risk…

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