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Abstracts tagged "diabetes and osteoarthritis"

  • Abstract Number: 2178 • ACR/ARHP Annual Meeting 2017

    Metabolic Osteoarthritis: Relation of Cardiovascular Disease and Diabetes to Knee Osteoarthritis

    Laura Kuusalo1, David T. Felson2, Carrie Brown3, Cora E. Lewis4, James Torner5 and Tuhina Neogi2, 1University of Turku and Turku University Hospital, Turku, Finland, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3Boston University School of Public Health, Boston, MA, 4University of Alabama Birmingham, Birmingham, AL, 5University of Iowa, Iowa City, IA

    Background/Purpose: Metabolic changes or low-grade inflammation related to cardiovascular disease (CVD) and diabetes have been hypothesized to contribute to the development of OA. Prior studies…
  • Abstract Number: 1128 • ACR/ARHP Annual Meeting 2015

    Insulin-Induced Cartilage Degradation in Osteoarthritis Is Associated to Defective Autophagy

    Beatriz Carames1, Madalena Ribeiro1,2, Paloma Lopez de Figueroa1, Alexandrina Mendes2 and Francisco J. Blanco1, 1Cartilage Biology Group. Rheumatology Division, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, 2Centre for Neuroscience and Cell Biology, University of Coimbra; Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

    Background/Purpose: Autophagy, a key cellular quality control mechanism, is defective in Osteoarthritis (OA) and Type 2 Diabetes (T2D). T2D has been proposed as a risk…

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