ACR Meeting Abstracts

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Abstracts tagged "dermatomyositis"

  • Abstract Number: 2221 • 2014 ACR/ARHP Annual Meeting

    Reduction of Ovarian Reserve in Adult Patients with Dermatomyositis

    Fernando Henrique Carlos de Souza1, Samuel Katsuyuki Shinjo1, Lucas Yugo Shiguehara Yamakami2, Vilma dos Santos Trindade Viana1, Edmund Chada Baracat3, Eloisa Bonfa4 and Clovis Artur Almeida Silva5, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Gynecology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 3Gynecology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 5Pediatric Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Dermatomyositis (DM) affects female gender during reproductive age, in which ovarian reserve and future fertility are major topics of interest. However, there is no…
  • Abstract Number: 2229 • 2014 ACR/ARHP Annual Meeting

    How Often Are Clinically Amyopathic Dermatomyositis Patients Truly Amyopathic?

    Edward J. Oberle1,2, Michelle Bayer3,4, Dominic O. Co4,5 and Yvonne Chiu4,5, 1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, 2Rheumatology, Children's Hospital of Wisconsin, Milwaukee, WI, 3Dermatology, Medical College of Wisconsin, Milwaukee, WI, 4Children's Hospital of Wisconsin, Milwaukee, WI, 5Pediatrics, Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Juvenile dermatomyositis (JDM) is a chronic inflammatory disorder primarily involving the skin and striated muscle.  Classic JDM presents with rash, proximal muscle weakness, and…
  • Abstract Number: 1272 • 2014 ACR/ARHP Annual Meeting

    Myositis-Specific and Myositis Associated Autoantibodies in Indian Patients with Inflammatory Myositis

    Puja Srivastava, Ramnath Misra, Able Lawrence, Amita Aggarwal and Vikas Agarwal, Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

    Background/Purpose Recently, idiopathic inflammatory myositis (IIM) has been categorised into distinct subsets based on myositis specific autoantibodies (MSA) and myositis associated autoantibodies (MAA). However, there is…
  • Abstract Number: 1266 • 2014 ACR/ARHP Annual Meeting

    Anti-MDA5 Is Associated with Rapidly-Progressive Interstitial Lung Disease and Poor Survival in U.S. Patients with Amyopathic and Myopathic Dermatomyositis

    Siamak Moghadam-Kia1, Chester V. Oddis2, Shinji Sato3, Masataka Kuwana4 and Rohit Aggarwal1, 1Medicine, University of Pittsburgh, Pittsburgh, PA, 2Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan, 4Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose : Clinically amyopathic dermatomyositis (CADM) is a subset of dermatomyositis (DM) presenting with the characteristic rash(es) of DM without objective muscle weakness. Asian studies…
  • Abstract Number: 2083 • 2013 ACR/ARHP Annual Meeting

    Environmental Factors Associated With Disease Flare In Juvenile and Adult Dermatomyositis

    Gulnara Mamyrova1, Lisa G. Rider2, Olcay Jones3, Alison Ehrlich4, Lauren M. Pachman5, Robert Nickeson6, Lisa G. Criscione-Schreiber7, Frederick W. Miller2, Lawrence K. Jung8 and James D. Katz1, 1Rheumatology, George Washington University, Washington, DC, 2Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 3Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, 4Dermatology, The George Washington University, Washington, DC, 5Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Pediatrics, All Children's Hospital, St Petersburg, FL, 7Dept of Med/Rheum Div, Duke University School of Medicine, Durham, NC, 8Pediatric Rheumatology, Children's National Medical Center, Washington, DC

    Background/Purpose: To assess environmental factors in relationship to increased disease activity (flare) in juvenile and adult dermatomyositis (DM). Methods: An online survey was conducted for…
  • Abstract Number: 1981 • 2013 ACR/ARHP Annual Meeting

    Developing International Consensus Definitions Of Improvement For Adult and Juvenile Dermatomyositis and Polymyositis

    Saad Feroz1, Nicolino. Ruperto2, Jiri Vencovsky3, Peter A. Lachenbruch1, Brian Erman4, Adam Huber5, Brian M. Feldman6, Ingrid E. Lundberg7, Angela Pistorio8, Howard Rockette9, Frederick W. Miller1, Rohit Aggarwal10, Lisa G. Rider1, for The ACR-EULAR Myositis Response Criteria Project Group11, Angelo Ravelli12, Clarissa Pilkington13 and Sheila K. Oliveira14, 1Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 2PRINTO, IRCCS G. Gaslini, Genoa, Italy, 3Institute of Rheumatology, Department of Clinical and Experimental Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 4SRA International, Research Triangle Park, NC, 5IWK Health Centre, Halifax, NS, Canada, 6Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 7Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, 8PRINTO, Genoa, Italy, 9University of Pittsburgh, Pittsburgh, PA, 10Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, 11NIEHS, NIH, Bethesda, MD, 12Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, 13Rheumatology Department, Great Ormond Street Hospital, London, United Kingdom, 14Pediatric Rheumatology, Instituto de Pediatria e Puericultura Martagão Gesteira (IPPMG) da Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

    Background/Purpose: IMACS and PRINTO have developed preliminary core set activity measures and definitions of improvement (DOIs). However, these were developed from small and partially retrospective…
  • Abstract Number: 1277 • 2013 ACR/ARHP Annual Meeting

    A Pilot Study Of Young Adults With Juvenile Dermatomyositis With Decreased Nailfold Capillary End Row Loops:  Brachial Artery Reactivity and Oxidized Lipids

    Lauren M. Pachman1,2, Maureen A. McMahon3, Tamar Polonsky4, Gabrielle A. Morgan1, Maria Amoruso5 and Chiang-Ching Huang6, 1Cure JM Myositis Center, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, IL, 2Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 4Cardiology, University of Chicago Medicine, Chicago, IL, 5Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Cure JM Myositis Center, Chicago, IL, 6Zilber School of Public Health, University of Wisconsin at Milwaukee, Milwaukee, WI

    Background/Purpose: Our center previously reported increased carotid intima media thickness, and lower high-density lipoprotein (HDL) levels in young or middle-age adults with a history of…
  • Abstract Number: 1271 • 2013 ACR/ARHP Annual Meeting

    Longitudinal Disease Trajectory Of Juvenile Dermatomyositis

    Lily Siok Hoon Lim1,2, Eleanor Pullenayegum3, Dafna D. Gladman4, Earl D. Silverman5 and Brian M. Feldman6, 1Pediatric Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 2Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada, 3Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, 4Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 6Rheumatology, Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: 1) To determine the longitudinal disease activity trajectory of an inception cohort of Juvenile Dermatomyositis (JDM) patients, 2) To identify predictor(s) for longitudinal disease…
  • Abstract Number: 853 • 2013 ACR/ARHP Annual Meeting

    Capillaroscopy Compared With Color Doppler Ultrasound Of Digital Arteries For Distinguishing Primary From Secondary Raynaud’s Phenomenon

    Wolfgang A. Schmidt1, Katharina Pagel2, Bernd Schicke3 and Andreas Krause4, 1Med Ctr Rheumatology Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 2Medical Ctr Rheumatol Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 3Tumorzentrum Berlin, Berlin, Germany, 4Immanuel Krankenhaus Berlin, Berlin, Germany

    Background/Purpose: Raynaud’s phenomenon (RP) is commonly seen in rheumatology practice. Differentiating primary from secondary RP is important for disease management and prognosis. How does capillaroscopy…
  • Abstract Number: 222 • 2013 ACR/ARHP Annual Meeting

    Comparison Of Whole Body Versus Targeted Magnetic Resonance Imaging For Assessing Disease Activity and Damage In Idiopathic Inflammatory Myopathies

    Adam Schiffenbauer1, Evrim Turkbey2, Lisa G. Rider1, Suvimol Hill2, Irene Z. Whitt3, Songtao Liu2, David A. Bluemke2 and Frederick W. Miller1, 1Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 2NIH, Bethesda, MD, 3Rheumatology and Immunology, Duke, Durham, NC

    Background/Purpose: In the idiopathic inflammatory myopathies (IIM) MRI imaging is traditionally focused on the proximal upper or lower extremities.  Whole body MRI (WBMRI) is a…
  • Abstract Number: 228 • 2013 ACR/ARHP Annual Meeting

    The Composition and Structure Of Calcifications In Juvenile Dermatomyositis Differs From Calcified Aortic Valves Removed From Adults Without JDM

    Lauren M. Pachman1,2, Gabrielle A. Morgan1, Patrick M. McCarthy3, Anna Huskin3, S. Chris Malaisrie3, Lyudmila Spevak4, Stephen Doty4 and Adele Boskey4, 1Cure JM Myositis Center, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, IL, 2Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Northwestern University Feinberg School of Medicine Bluhm Cardiovascular Institute, Chicago, IL, 4Hospital for Special Surgery, New York, NY

    Background/Purpose: Juvenile Dermatomyositis (JDM) is a systemic vasculopathy, primarily involving the micro vasculature. Soft tissue calcification occurs in 15-30% of cases, and is associated with…
  • Abstract Number: 210 • 2012 ACR/ARHP Annual Meeting

    An Analysis of Metabolic Syndrome in Adult Dermatomyositis with a Focus On Cardiovascular Disease

    Mariana T. Moraes1, Fernando H.C. Souza2, Thiago B. M. Barros1 and Samuel K. Shinjo1, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Metabolic syndrome (MetS) is a cluster of metabolic abnormalities associated with increased cardiovascular risk. MetS has been systematically evaluated in all systemic autoimmune rheumatic…
  • Abstract Number: 206 • 2012 ACR/ARHP Annual Meeting

    Clinical, Laboratory, and Cellular Responses in the Rituximab in Myositis Trial in Patients Enrolled At the National Institutes of Health

    Lisa G. Rider1, Adrienne L. Yip2, Iren Horkayne-Szakaly3, Rita Volochayev2, Joseph A. Shrader4, Maria L. Turner5, Heidi H. Kong5, Minal S. Jain4, Anna V. Jansen1, Chester V. Oddis6, Thomas A. Fleisher7 and Frederick W. Miller1, 1Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, 2National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, 3Joint Pathology Center, Silver Spring, MD, 4Rehabilitation Medicine, Rehab Medicine, NIH Clinical Center, Bethesda, MD, 5Dermatology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD, 6Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 7Laboratory Medicine, Laboratory Medicine, NIH Clinical Center, Bethesda, MD

    Background/Purpose: To assess changes in myositis core set measures, clinical and laboratory data, and paired muscle biopsies from NIH patients enrolled in the Rituximab in…
  • Abstract Number: 1955 • 2012 ACR/ARHP Annual Meeting

    Is the Pattern of Capillary Deposition of Complement Membrane Attack COPMLEX  Useful in the Differential Diagnosis of Inflammatory?

    Patrick Gordon1, Nuria Villagra2, Istvan Bodi2, Andrew King2, Stefan Buk2, Tibor Hortobagyi2 and Safa Al-Sarraj2, 1Department of Rheumatology, King's College London, London, United Kingdom, 2Department of Clinical Neuropathology, King's College Hospital, London, United Kingdom

    Background/Purpose: Inflammatory myopathies are a heterogeneous group of diseases. We investigated if the location and pattern of deposition of complement membrane attack complex (MAC) can…
  • Abstract Number: 1937 • 2012 ACR/ARHP Annual Meeting

    HLA-DRB1*0101/*0405 Is Associated with Susceptibility to Anti-MDA5 Antibody-Positive Dermatomyositis in the Japanese Population

    Takahisa Gono1, Yasushi Kawaguchi1, Masataka Kuwana2, Tomoko Sugiura1, Takefumi Furuya1, Kae Takagi1, Hisae Ichida1, Yasuhiro Katsumata1, Masanori Hanaoka1, Yuko Okamoto1, Yuko Ota1, Sayuri Kataoka1 and Hisashi Yamanaka1, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

    Background/Purpose: The complication of interstitial lung disease (ILD) is associated with the anti-aminoacyl tRNA synthetase antibody (ARS ab) or the anti-melanoma differentiation-associated gene 5 antibody…
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