Abstracts tagged "dendritic cells and systemic sclerosis"

Abstract Number: 1123 • ACR/ARHP Annual Meeting 2018
Plasmacytoid Dendritic Cells in Bronchoalveolar Lavage Correlate with Pulmonary Artery Diameter and Infiltrate Perivascular Areas in the Lungs from Patients with Systemic Sclerosis Associated Pulmonary Hypertension
Isela Valera¹, Anagha Divekar², Dinesh Khanna³, Fereidoun Abtin⁴, Rajan Saggar⁴ and Ram R. Singh⁴, ¹Autoimmunity and Tolerance Laboratory, Division of Rheumatology, Department of Medicine, UCLA, Los Angeles, CA, ²Biolegend, Sa Diego, CA, ³Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, University of Michigan, Ann Arbor, MI, ⁴UCLA, Los Angeles, CA
Background/Purpose: In patients with systemic sclerosis (SSc), plasmacytoid dendritic cells (pDCs) increase in the bronchoalveolar lavage (BAL) and lung tissues (Kafaja S, et al, JCI…
Abstract Number: 950 • ACR/ARHP Annual Meeting 2017
Identification of Naturally Processed Immunodominant Topoisomerase I Epitopes in Patients with Systemic Sclerosis
Eleni Tiniakou¹, Andrea Fava², Tara Guhr³, Francesco Boin⁴ and Erika Darrah⁵, ¹Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³University of North Carolina, Chapel Hill, NC, ⁴Rheumatology, University California, San Francisco, San Francisco, CA, ⁵Department of Medicine/Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Identification of immunodominant T cell epitopes of autoantigens is crucial to understanding the pathogenesis of autoimmune diseases and developing disease-specific diagnostic and therapeutic tools.…